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Cancer Research, ISSN 0008-5472, 2010, Volume 70, Issue 11, pp. 4528 - 4538
MicroRNA-21 (miR-21) was reported to be overexpressed and contributes to invasion and gemcitabine resistance in pancreatic ductal adenocarcinoma (PDAC). The... 
SURVIVAL | CELLS | INVASION | METASTASIS | INHIBITION | ONCOLOGY | PHOSPHORYLATION | POOR-PROGNOSIS | ADENOCARCINOMA | EXPRESSION PROFILES | CHEMOTHERAPY | Vascular Endothelial Growth Factor A - biosynthesis | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Humans | Middle Aged | Carcinoma, Pancreatic Ductal - metabolism | Apoptosis - genetics | Carcinoma, Pancreatic Ductal - genetics | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | RNA, Messenger - biosynthesis | Deoxycytidine - therapeutic use | Matrix Metalloproteinase 9 - genetics | Aged, 80 and over | Adult | Retrospective Studies | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Matrix Metalloproteinase 2 - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Cell Growth Processes - drug effects | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | PTEN Phosphohydrolase - biosynthesis | MicroRNAs - biosynthesis | Pancreatic Neoplasms - genetics | Treatment Outcome | Carcinoma, Pancreatic Ductal - pathology | Proto-Oncogene Proteins c-akt - biosynthesis | Carcinoma, Pancreatic Ductal - drug therapy | Matrix Metalloproteinase 2 - genetics | Antimetabolites, Antineoplastic - therapeutic use | Cell Line, Tumor | Aged | MicroRNAs - genetics | Deoxycytidine - analogs & derivatives | Index Medicus
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2009, Volume 9, Issue 1, pp. 20 - 20
Background: The metastatic disease rather than the primary tumor itself is responsible for death in most solid tumors, including breast cancer. The role of... 
KAZAL MOTIFS | MATRIX METALLOPROTEINASES | LUNG-CANCER | IN-VITRO | CYSTEINE-RICH PROTEIN | ONCOLOGY | RT-PCR | EXTRACELLULAR-MATRIX | PROGNOSTIC-SIGNIFICANCE | CARCINOMA | RNA EXPRESSION | Matrix Metalloproteinases - genetics | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Humans | Membrane Glycoproteins - biosynthesis | GPI-Linked Proteins | Tissue Inhibitor of Metalloproteinase-2 - genetics | Breast Neoplasms - metabolism | Tissue Inhibitor of Metalloproteinases - genetics | Matrix Metalloproteinase 14 - biosynthesis | RNA, Messenger - biosynthesis | Breast Neoplasms - enzymology | Neoplasm Metastasis | Matrix Metalloproteinase 9 - genetics | Tissue Inhibitor of Metalloproteinase-2 - biosynthesis | Matrix Metalloproteinase 2 - biosynthesis | Tissue Inhibitor of Metalloproteinases - biosynthesis | Matrix Metalloproteinases - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Neoplasm Invasiveness | RNA, Messenger - genetics | Reverse Transcriptase Polymerase Chain Reaction | Membrane Glycoproteins - genetics | Matrix Metalloproteinase 2 - genetics | Tissue Inhibitor of Metalloproteinase-1 - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Care and treatment | Prognosis | Enzyme inhibitors | Proteases | Breast cancer | Genetic aspects | Dosage and administration | Research | Gene expression | Health aspects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, pp. e21816 - e21816
Background: IL-17A is a pro-inflammatory cytokine that plays important role in inflammatory disease pathology and tumor microenvironment. The aim of this study... 
RHEUMATOID-ARTHRITIS | ACTIVATED MONOCYTES | MULTIDISCIPLINARY SCIENCES | IL-17 | EXPANSION | KAPPA-B | TUMOR-GROWTH | CANCER | T-CELLS | PROGRESSION | TH17 CELLS | Gene Expression Regulation, Enzymologic - drug effects | Multivariate Analysis | Prognosis | Humans | Middle Aged | Epithelial-Mesenchymal Transition - drug effects | Male | NF-kappa B - metabolism | Interleukin-17 - pharmacology | Neoplasm Metastasis | Matrix Metalloproteinase 9 - genetics | Carcinoma, Hepatocellular - genetics | Enzyme Induction - drug effects | Female | Liver Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Liver Neoplasms - enzymology | Matrix Metalloproteinase 2 - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Liver Neoplasms - genetics | Neoplasm Invasiveness | Carcinoma, Hepatocellular - enzymology | Recombinant Proteins - pharmacology | Up-Regulation - drug effects | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Carcinoma, Hepatocellular - pathology | Survival Analysis | Aged | Cell Proliferation - drug effects | Immunohistochemistry | Medical research | Interleukins | Analysis | Medicine, Experimental | Development and progression | Hepatoma | Health sciences | Transcription factors | Matrix metalloproteinases | Transcription | Leukocyte migration | Laboratories | Interleukin | Oncology | Hepatocellular carcinoma | Metastasis | Tissues | Metastases | Independent sample | Morphogenesis | Liver cancer | Signal transduction | Lymphocytes | NF-κB protein | Cytokines | Breast cancer | Gelatinase B | Gelatinase A | Medicine | Studies | Survival analysis | Signaling | Medical prognosis | Kidney cancer | Cell migration | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2006, Volume 26, Issue 43, pp. 10939 - 10948
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2003, Volume 170, Issue 6, pp. 3369 - 3376
IL-8, a member of the chemokine family, has been shown to play an important role in tumor growth, angiogenesis, and metastasis. The objective of this study was... 
CARCINOMA-CELLS | C-X-C | BCL-X | HUMAN-MELANOMA CELLS | NON-HODGKINS-LYMPHOMA | MALIGNANT-MELANOMA | IMMUNOLOGY | TUMOR-GROWTH | HUMAN INTERLEUKIN-8 | EXPRESSION | CANCER | Endothelium, Vascular - cytology | Matrix Metalloproteinases - genetics | Receptors, Interleukin-8A - biosynthesis | Humans | Receptors, Interleukin-8A - genetics | Cell Survival - genetics | Apoptosis - genetics | Interleukin-8 - physiology | Endothelium, Vascular - enzymology | Cell Movement - genetics | Capillaries - physiology | Cell Movement - immunology | RNA, Messenger - biosynthesis | Cell Division - immunology | Matrix Metalloproteinase 9 - genetics | Interleukin-8 - metabolism | Matrix Metalloproteinase 2 - biosynthesis | Endothelium, Vascular - immunology | Matrix Metalloproteinases - biosynthesis | Cell Division - genetics | Receptors, Interleukin-8B - physiology | Recombinant Proteins - metabolism | Cell Line | Matrix Metalloproteinase 9 - biosynthesis | Neovascularization, Physiologic - genetics | Up-Regulation - genetics | Recombinant Proteins - pharmacology | Cell Survival - immunology | Neovascularization, Physiologic - immunology | Down-Regulation - genetics | Matrix Metalloproteinase 2 - genetics | Apoptosis - immunology | Receptors, Interleukin-8B - biosynthesis | Up-Regulation - immunology | Down-Regulation - immunology | Endothelium, Vascular - metabolism | Receptors, Interleukin-8B - genetics | Receptors, Interleukin-8A - physiology | Index Medicus | Abridged Index Medicus
Journal Article
Experimental Neurology, ISSN 0014-4886, 2010, Volume 226, Issue 1, pp. 183 - 190
Blood–brain barrier (BBB) breakdown after stroke is linked to the up-regulation of metalloproteinases (MMPs) and inflammation. This study examines the effects... 
Permanent middle cerebral artery occlusion | Tumor necrosis factor-alpha | Cytokines | Ischemia | Tight junction proteins | Inflammatory response | Progesterone | Metalloproteinases | Allopregnanolone | Blood–brain barrier | Blood-brain barrier | MIDDLE CEREBRAL-ARTERY | FUNCTIONAL DEFICITS | MALE RATS | EXPERIMENTAL STROKE | GENE KNOCK-OUT | NEUROSCIENCES | INFARCT VOLUME | PLASMINOGEN-ACTIVATOR | NEUROPROTECTIVE FACTOR | MEDIATED DISRUPTION | CENTRAL-NERVOUS-SYSTEM | Immunohistochemistry | Male | Occludin | Brain Ischemia - enzymology | Stroke - pathology | Ligation | Progesterone - pharmacology | Matrix Metalloproteinase 2 - biosynthesis | Matrix Metalloproteinases - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Brain Edema - pathology | Rats | Claudin-5 | Middle Cerebral Artery - pathology | Stroke - drug therapy | Infarction, Middle Cerebral Artery - pathology | Permeability | Blood-Brain Barrier - drug effects | Rats, Sprague-Dawley | Blotting, Western | Membrane Proteins - biosynthesis | Animals | Blood-Brain Barrier - enzymology | Pregnanolone - pharmacology | Brain Ischemia - pathology | Interleukin-6 - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | Proteins | Analysis | Index Medicus | blood-brain barrier | tumor necrosis factor-alpha | progesterone | inflammatory response | metalloproteinases | tight junction proteins | allopregnanolone | cytokines | permanent middle cerebral artery occlusion | ischemia
Journal Article
Cancer Science, ISSN 1347-9032, 06/2014, Volume 105, Issue 6, pp. 630 - 638
Calpain small subunit 1 (Capn4) plays a key role in tumor migration or invasion. In this study, expression and function of Capn4 was investigated in human... 
nasopharyngeal carcinoma | nuclear factor‐κB | Capn4 | metastasis | matrix metalloproteinase 2 | Nasopharyngeal carcinoma | Matrix metalloproteinase 2 | Metastasis | Nuclear factor-κB | Phosphorylation | Carcinoma | Nasopharyngeal Neoplasms - mortality | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Calpain - genetics | Cadherins - biosynthesis | Cell Movement - genetics | Nasopharyngeal Neoplasms - pathology | RNA, Messenger - biosynthesis | Neoplasm Metastasis | RNA Interference | Female | Snail Family Transcription Factors | Matrix Metalloproteinase 2 - biosynthesis | Nasopharyngeal Carcinoma | Vimentin - biosynthesis | Neoplasm Invasiveness | Transcription Factors - biosynthesis | Disease-Free Survival | Animals | Transcription Factor RelA - metabolism | Mice, Nude | Focal Adhesions - metabolism | Calpain - biosynthesis | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Mice, Inbred BALB C | RNA, Small Interfering | Enzyme Activation | Epstein-Barr Virus Infections - metabolism | Biomarkers, Tumor - biosynthesis | Vimentin | Biotechnology | Epithelial cells | Pathogenesis | mRNA | Matrix metalloproteinase | Lymph nodes | Metastases | Cell adhesion & migration | Proteins | Cell cycle | Metalloproteinase | Cell survival | Therapeutic applications | Calpain | siRNA | Gelatinase A | Medical prognosis | Cell lines | Biomarkers | Laboratory animals | Cell migration | Apoptosis | Index Medicus | nuclear factor-κB | Original
Journal Article