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Gene, ISSN 0378-1119, 09/2016, Volume 589, Issue 1, pp. 81 - 89
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e20164
Background: Diosgenin, a steroidal saponin obtained from fenugreek (Trigonella foenum graecum), was found to exert anti-carcinogenic properties, such as... 
APOPTOSIS | SIGNALING PATHWAYS | ACTIVATION | METASTASIS | ANGIOGENESIS | COLORECTAL-CANCER | KINASE | BIOLOGY | CYCLE ARREST | OSTEOSARCOMA CELLS | PROGRESSION | Prostatic Neoplasms - metabolism | Humans | Immunoblotting | JNK Mitogen-Activated Protein Kinases - metabolism | Male | NF-kappa B - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Tissue Inhibitor of Metalloproteinase-2 - genetics | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 7 - metabolism | Basigin - genetics | Matrix Metalloproteinase 9 - genetics | Polymerase Chain Reaction | JNK Mitogen-Activated Protein Kinases - genetics | Phosphatidylinositol 3-Kinase - metabolism | Diosgenin - pharmacology | Matrix Metalloproteinase 2 - metabolism | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase 7 - genetics | NF-kappa B - genetics | Phosphatidylinositol 3-Kinase - genetics | Basigin - metabolism | Cell Line, Tumor | Progesterone | Metastasis | Vascular endothelial growth factor | Health aspects | Prostate cancer | Apoptosis | Transcription factors | Boyden chamber | Matrix metalloproteinases | Leukocyte migration | AKT protein | Assaying | Metastases | Proteins | Angiogenesis | Cell growth | Gelatin | Inhibition | Enzymes | NF-κB protein | Medical technology | Wound healing | Gene expression | 1-Phosphatidylinositol 3-kinase | Pharmacy | Cell migration | Cell proliferation | Biotechnology | Tissue inhibitor of metalloproteinases | Phosphorylation | Colorectal cancer | Science | mRNA | Matrix metalloproteinase | Kinases | Cell adhesion & migration | Carcinogens | Cell cycle | Fenugreek | Metalloproteinase | Tumor cells | Extracellular signal-regulated kinase | c-Jun protein | Breast cancer | Endothelial cells | Gelatinase B | Gelatinase A | Signaling | Collagen | Prostate | Tumors | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 03/2010, Volume 70, Issue 6, pp. 2224 - 2234
Journal Article
Matrix Biology, ISSN 0945-053X, 2011, Volume 30, Issue 2, pp. 145 - 153
Aggrecan degradation in articular cartilage occurs predominantly through proteolysis and has been attributed to the action of members of the matrix... 
MMP | ADAMTS | Interglobular domain | Chondroitin-sulfate-2 region | Aggrecan catabolism | RHEUMATOID-ARTHRITIS | PROTEOLYTIC CLEAVAGE | CLEAVAGE SITE | ACTIVATION MECHANISMS | LARGE AGGREGATING PROTEOGLYCAN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | HUMAN ARTICULAR-CARTILAGE | MATRIX METALLOPROTEINASES | OSTEOARTHRITIC CARTILAGE | ONCOSTATIN-M | Matrix Metalloproteinases, Secreted - metabolism | Interleukin-1beta - pharmacology | Phenylmercuric Acetate - pharmacology | Matrix Metalloproteinase 12 - genetics | Cartilage - drug effects | Oncostatin M - pharmacology | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 7 - metabolism | Cattle | Isoenzymes - metabolism | Matrix Metalloproteinase 8 - metabolism | Gelatinases - metabolism | Matrix Metalloproteinase 1 - genetics | Recombinant Proteins - metabolism | Endopeptidases - metabolism | Matrix Metalloproteinase 8 - genetics | Peptide Fragments - metabolism | Isoenzymes - genetics | Matrix Metalloproteinase 2 - metabolism | Matrix Metalloproteinase 3 - metabolism | Aggrecans - metabolism | Matrix Metalloproteinase 12 - metabolism | Cartilage - metabolism | Aggrecans - genetics | ADAM Proteins - metabolism | Enzyme Precursors - metabolism | Matrix Metalloproteinase 7 - genetics | Animals | Endopeptidases - genetics | Matrix Metalloproteinases, Secreted - genetics | Phenylmercuric Acetate - analogs & derivatives | ADAM Proteins - genetics | Cartilage - enzymology | Matrix Metalloproteinase 1 - metabolism | Matrix Metalloproteinase 3 - genetics
Journal Article
Journal Article
Journal Article
Histopathology, ISSN 0309-0167, 03/2014, Volume 64, Issue 4, pp. 512 - 522
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0202759
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2010, Volume 11, Issue 1, pp. 76 - U1
Journal Article
Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 1870
Mesothelin (MSLN) and cancer antigen125/mucin 16 (CA125/MUC16) are potential biomarkers for pancreatic cancer (PC) that are co-overexpressed at the invading... 
MIGRATION | VARIANT ISOFORMS | DUCTAL ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | OVARIAN-CANCER | MUCIN 16 | EXPRESSION | COLON-CARCINOMA CELLS | SELECTIN LIGAND | MATRIX METALLOPROTEINASE-7 | ANTIGEN | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Cell Proliferation | Immunoprecipitation | Pancreatic Neoplasms - metabolism | CA-125 Antigen - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Immunoenzyme Techniques | Carcinoma, Pancreatic Ductal - genetics | Adenocarcinoma - metabolism | Matrix Metalloproteinase 7 - metabolism | Adenocarcinoma - genetics | Membrane Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Tumor Cells, Cultured | CA-125 Antigen - metabolism | Real-Time Polymerase Chain Reaction | Enzyme-Linked Immunosorbent Assay | Membrane Proteins - genetics | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Pancreatic Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Pancreatic Ductal - pathology | Blotting, Western | GPI-Linked Proteins - metabolism | Matrix Metalloproteinase 7 - chemistry | Matrix Metalloproteinase 7 - genetics | Enzyme Activation | Cell Movement | GPI-Linked Proteins - genetics | Motility | Cell survival | Mucin | Invasiveness | Pancreatic cancer | Pheochromocytoma cells | MAP kinase | Metalloproteinase | Matrix metalloproteinase | Matrilysin | Metastases
Journal Article