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Journal of Cell Science, ISSN 0021-9533, 10/2011, Volume 124, Issue 19, pp. 3369 - 3380
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2015, Volume 36, Issue 11, pp. 2963 - 2971
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 51, pp. 20262 - 20267
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2005, Volume 25, Issue 27, pp. 6401 - 6408
Neuronal cell death occurs during many neurodegenerative disorders and stroke. The aberrant, excessive activity of matrix metalloproteinases (MMPs), especially... 
Laminin | Matrix metalloproteinases | Thiirane inhibitor | Neurons | Proteolysis | Apoptosis | HEMORRHAGE | INCREASES | apoptosis | CASCADE | INDUCTION | neurons | CANCER | NEUROSCIENCES | thiirane inhibitor | STROKE | HIPPOCAMPUS | TISSUE-PLASMINOGEN-ACTIVATOR | laminin | matrix metalloproteinases | EXPRESSION | proteolysis | Matrix Metalloproteinase 9 - physiology | Cerebral Infarction - drug therapy | Neurons - pathology | Sulfones - therapeutic use | Apoptosis - drug effects | Enzyme Precursors - pharmacology | Matrix Metalloproteinase 9 - pharmacology | Ischemic Attack, Transient - enzymology | Sulfones - pharmacology | Cerebral Infarction - enzymology | Heterocyclic Compounds, 1-Ring - administration & dosage | Protease Inhibitors - pharmacology | Matrix Metalloproteinases, Membrane-Associated | Reperfusion | Heterocyclic Compounds, 1-Ring - pharmacology | Collagenases - pharmacology | Protease Inhibitors - administration & dosage | Drug Evaluation, Preclinical | Neurons - drug effects | Protease Inhibitors - therapeutic use | Cerebral Infarction - pathology | Ischemic Attack, Transient - pathology | Matrix Metalloproteinases - pharmacology | Infusion Pumps, Implantable | Ischemic Attack, Transient - drug therapy | Drug Administration Schedule | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | Animals | Neurons - enzymology | Heterocyclic Compounds, 1-Ring - therapeutic use | Matrix Metalloproteinase Inhibitors | Mice | Kinetics | Laminin - metabolism | Sulfones - administration & dosage | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e80933 - e80933
Brain metastasis is a defining component of tumor pathophysiology, and the underlying mechanisms responsible for this phenomenon are not well understood.... 
PATHOGENESIS | BREAST-CANCER CELLS | HEMATOGENOUS METASTASES | BRAIN METASTASIS | RAT | MICROENVIRONMENT | LUNG-CARCINOMA | MULTIDISCIPLINARY SCIENCES | COLONIZATION | ENERGY-METABOLISM | EXPRESSION | Neoplasm Transplantation | Humans | Lung Neoplasms - metabolism | Neoplasm Invasiveness - prevention & control | Astrocytes - pathology | Culture Media, Conditioned - chemistry | Lung Neoplasms - pathology | Male | Matrix Metalloproteinase 9 - pharmacology | Breast Neoplasms - metabolism | Protease Inhibitors - pharmacology | Matrix Metalloproteinase 9 - metabolism | Neoplasm Invasiveness - pathology | Biological Factors - secretion | Female | Matrix Metalloproteinase 9 - secretion | Tumor Cells, Cultured | Biological Factors - metabolism | Matrix Metalloproteinase 2 - pharmacology | Animals, Newborn | Matrix Metalloproteinase 2 - metabolism | Rats | Hippocampus - pathology | Rats, Sprague-Dawley | Hippocampus - metabolism | Animals | Breast Neoplasms - pathology | Cell Line, Tumor | Matrix Metalloproteinase 2 - secretion | Mice | Primary Cell Culture | Biological Factors - pharmacology | Astrocytes - secretion | Care and treatment | Metastasis | Cancer | Neonates | Brain | Pediatrics | Cell culture | Pathogenesis | Brain cancer | Lung | Matrix metalloproteinase | Metastases | Blood-brain barrier | Physiology | Metalloproteinase | Conditioning | Immunoglobulins | Cytokines | Research & development--R&D | Tumor cells | Astrocytes | Invasiveness | Breast cancer | Permeability | Gelatinase B | Gelatinase A | Hypotheses | Brain research | Proteomics | Cell migration | Index Medicus | Research & development | R&D
Journal Article
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2008, Volume 44, Issue 13, pp. 1904 - 1913
Abstract Angiogenesis is crucial for the progression of colorectal carcinomas in which the bioavailability of Vascular Endothelial Growth Factor (VEGF) plays a... 
Hematology, Oncology and Palliative Medicine | MMP-2 | Myofibroblast | Growth factor release | Spheroid | Neutrophil | Matrix metalloproteinase | Tumour microenvironment | Gelatinase B | Gelatinase A | myofibroblast | TISSUE | FACTOR EXPRESSION | growth factor release | neutrophil | BIOAVAILABILITY | spheroid | MATRIX METALLOPROTEINASES | ONCOLOGY | GASTRIC-CANCER | gelatinase A | matrix metalloproteinase | gelatinase B | tumour microenvironment | EXTRACELLULAR-MATRIX | SWITCH | UP-REGULATION | CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | Matrix Metalloproteinase 9 - physiology | Cell Hypoxia - physiology | Colorectal Neoplasms - blood supply | Enzyme-Linked Immunosorbent Assay | Matrix Metalloproteinase 2 - metabolism | Antibodies, Monoclonal - pharmacology | Humans | Angiogenesis Inhibitors - pharmacology | Extracellular Matrix - metabolism | Matrix Metalloproteinase 9 - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Heparitin Sulfate - metabolism | Bevacizumab | HT29 Cells | Antibodies, Monoclonal, Humanized | Neovascularization, Pathologic - metabolism | Spheroids, Cellular | Neutrophils - metabolism | Development and progression | Glycosaminoglycans | Vascular endothelial growth factor | Analysis | Colorectal cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 49, pp. 19520 - 19525
Journal Article
Cellular Signalling, ISSN 0898-6568, 2012, Volume 24, Issue 2, pp. 549 - 559
CD44 is implicated in cell–cell and cell–matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic... 
Xenograft cells | MMP-9 | CD44 | Invasion | Glioblastoma | COMPLEX | MEMBRANE-TYPE-1 MATRIX-METALLOPROTEINASE | TUMOR-CELLS | CELL BIOLOGY | PROSTATE-CANCER CELLS | GELATINASE-B | MATRIX-METALLOPROTEINASE-9 | SURFACE | MALIGNANT GLIOMAS | EXPRESSION | RNA, Small Interfering - genetics | Immunoprecipitation | Humans | Transplantation, Heterologous | Cell Membrane - genetics | Hyaluronan Receptors - chemistry | Matrix Metalloproteinase 9 - pharmacology | Cell Movement - genetics | Gene Knockdown Techniques | Glioblastoma - genetics | Matrix Metalloproteinase 9 - genetics | Proteolysis | Hyaluronan Receptors - metabolism | Glioblastoma - metabolism | Cell Membrane - metabolism | Cell Membrane - drug effects | Protein Structure, Tertiary | Gene Expression | Enzyme Inhibitors - pharmacology | Matrix Metalloproteinase 9 - deficiency | Hyaluronan Receptors - genetics | Cell Movement - drug effects | Animals | Signal Transduction - drug effects | Glioblastoma - pathology | Cell Line, Tumor | Matrix Metalloproteinase Inhibitors | Mice | Enzyme Activation | Neoplasm Invasiveness - genetics | RNA, Small Interfering - metabolism | Metastasis | Hyaluronic acid | Glioblastoma multiforme | Cells | Enzymes | Transcription | Tumor cells | Confocal microscopy | Cell surface | Gelatinase B | Metastases | CD44 antigen | Xenografts | Supplementation | Cell migration | Cancer | Tumors | Index Medicus | glioblastoma | xenograft cells | invasion
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2012, Volume 122, Issue 4, pp. 775 - 788
Matrix metalloproteinase‐9 is an extracellularly operating protease that is expressed and released in the brain in response to enhanced neuronal activity. In... 
SynCAM‐2 | degradome | synaptoneurosomes | CRMP‐2 | MMP‐9 | proteolysis | CRMP-2 | SynCAM-2 | MMP-9 | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | GENE KNOCK-OUT | NEUROSCIENCES | MATRIX METALLOPROTEINASE-2 AND-9 | NEURONAL DEATH | EPILEPTIC SEIZURES | LONG-TERM POTENTIATION | RAT-BRAIN | Electrophoresis, Gel, Two-Dimensional | Male | Matrix Metalloproteinase 9 - pharmacology | N-Methylaspartate - pharmacology | Intercellular Signaling Peptides and Proteins - metabolism | Tandem Mass Spectrometry | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Hippocampus - enzymology | Hippocampus - ultrastructure | Densitometry | Glutamic Acid - pharmacology | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Synaptosomes - enzymology | Excitatory Amino Acid Agonists - pharmacology | Microscopy, Electron | Neural Cell Adhesion Molecules - genetics | Nerve Tissue Proteins - genetics | Synaptosomes - ultrastructure | Blotting, Western | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Neural Cell Adhesion Molecules - metabolism | Mice | Brain | Neurons | Fluorescence | Glutamate | Proteins | Methyl aspartate | Proteases | Proteolysis | Analysis | Physiological aspects | Mass spectrometry | Injuries | Antigenic determinants | Neurochemistry | Rodents | Index Medicus
Journal Article