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2012, 1. Aufl., EXS, ISBN 303480363X, Volume no. 103., x, 285
Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very... 
Metalloproteinases | Inhibitors | Biology, life sciences | Pharmacology
Book
Journal Article
2015, ISBN 9781118772324
Web Resource
Circulation, ISSN 0009-7322, 02/2006, Volume 113, Issue 6, pp. 834 - 841
Journal Article
Journal Article
2001, Methods in molecular biology, ISBN 9780896037335, Volume 151, xv, 545
From the simple discovery in 1962 that resorbing tadpole tail expressed an enzyme (MMP) that could degrade collagen gels, matrix metalloproteinase (MMP)... 
Metalloproteinases | Extracellular matrix proteins | Biochemistry, general | Biochemistry | Life Sciences
Book
American Journal of Pathology, ISSN 0002-9440, 04/2017, Volume 187, Issue 4, pp. 781 - 797
In three-dimensional extracellular matrix, mesenchymal cells including hepatic stellate cells (HSCs) gain the ability to express matrix metalloproteinases... 
ACTIVATION | TGF-BETA | LIVER | SEQUENCE | INJURY | II HISTONE DEACETYLASES | PATHOLOGY | INHIBITOR | TRANSCRIPTION FACTOR | MYOCYTE ENHANCER FACTOR-2 | MYOFIBROBLASTIC DIFFERENTIATION | Rats, Wistar | Humans | Extracellular Matrix - metabolism | Hepatic Stellate Cells - metabolism | Male | Cathepsin L - metabolism | Enzyme Stability - drug effects | Liver Cirrhosis - enzymology | RNA, Messenger - metabolism | Myofibroblasts - metabolism | Proteolysis - drug effects | Matrix Metalloproteinase 9 - metabolism | Cell Nucleus - metabolism | Biocatalysis - drug effects | Cell Transdifferentiation - drug effects | Protein Binding - drug effects | Liver Cirrhosis - metabolism | Epigenesis, Genetic - drug effects | Liver Cirrhosis - genetics | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | Cell Line | Myofibroblasts - pathology | Extracellular Matrix - drug effects | Matrix Metalloproteinase 13 - genetics | RNA, Messenger - genetics | Histone Deacetylases - metabolism | Down-Regulation - drug effects | Myofibroblasts - drug effects | Subcellular Fractions - metabolism | Down-Regulation - genetics | Matrix Metalloproteinase 13 - metabolism | Cathepsin H - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Animals | Liver Cirrhosis - pathology | Mice | Cell Nucleus - drug effects | Index Medicus | Abridged Index Medicus | Regular
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2009, Volume 284, Issue 34, pp. 23001 - 23011
Fibroblasts degrade type I collagen, the major extracellular protein found in mammals, during events ranging from bulk tissue resorption to invasion through... 
1-MATRIX METALLOPROTEINASE | TYPE-1 MATRIX-METALLOPROTEINASE | SUBSTRATE DEGRADATION | GELATINASE-A | CELL-MIGRATION | CYSTEINE PROTEINASES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TARGETED MUTATION | EXTRACELLULAR-MATRIX | DEFICIENT MICE | MEDIATED INHIBITION | Matrix Metalloproteinase 9 - physiology | Matrix Metalloproteinase 8 - physiology | Matrix Metalloproteinase 2 - physiology | Tissue Inhibitor of Metalloproteinase-2 - genetics | Protease Inhibitors - pharmacology | Matrix Metalloproteinase 9 - genetics | Plasminogen - pharmacology | Matrix Metalloproteinase 16 - genetics | Membrane Proteins - metabolism | Fibroblasts - metabolism | Matrix Metalloproteinase 8 - genetics | Collagen Type I - metabolism | Proto-Oncogene Proteins c-sis | Matrix Metalloproteinase 13 - genetics | Mice, Inbred C57BL | Cells, Cultured | Platelet-Derived Growth Factor - pharmacology | Microscopy, Electron | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Tissue Inhibitor of Metalloproteinase-2 - physiology | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase 14 - physiology | Animals | Matrix Metalloproteinase 16 - physiology | Matrix Metalloproteinase 13 - physiology | Fibroblasts - drug effects | Fluorescent Antibody Technique | Matrix Metalloproteinase 14 - genetics | Cell Proliferation - drug effects | Mice | Collagenases - metabolism | Index Medicus | Molecular Basis of Cell and Developmental Biology
Journal Article
1998, Biology of extracellular matrix series, ISBN 0125450907, 375
The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest... 
Extracellular matrix | Extracellular enzymes | Metalloproteinases | enzymology | Biology, life sciences | Extracellular matrix proteins
eBook
Liver International, ISSN 1478-3223, 09/2012, Volume 32, Issue 8, pp. 1278 - 1286
Background: Matrix metalloproteinase belong to family of pericellular collagenases which degrade extracellular matrix (ECM), and is involved in the modulation... 
genetic variants | gallbladder cancer | tissue inhibitor of metalloproteinases | matrix metalloproteinases | Tissue inhibitor of metalloproteinases | Matrix metalloproteinases | Genetic variants | Gallbladder cancer | FUNCTIONAL POLYMORPHISMS | OVARIAN-CANCER | CHINESE POPULATION | BREAST-CANCER | LUNG-CANCER | PROMOTER POLYMORPHISMS | GASTRIC-CANCER | COLORECTAL-CANCER | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | CARCINOMA | Haplotypes | Multivariate Analysis | Genetic Predisposition to Disease - genetics | Models, Chemical | Gallbladder Neoplasms - epidemiology | Humans | Middle Aged | Risk Factors | Gallbladder Neoplasms - genetics | India - epidemiology | Logistic Models | Male | Tissue Inhibitor of Metalloproteinase-2 - genetics | Polymorphism, Genetic | Genetic Variation | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase 7 - genetics | Matrix Metalloproteinase 9 - genetics | Adult | Female | Genetic Predisposition to Disease - epidemiology | Matrix Metalloproteinase 9 - chemistry | Index Medicus | Statistical analysis | Liver | Matrix metalloproteinase | Tissue inhibitor of metalloproteinase 2 | Guanylate cyclase | Gene polymorphism | Gelatinase B | Risk factors | Gelatinase A | Polymerase chain reaction | Restriction fragment length polymorphism | Genotyping | Collagen | Extracellular matrix | Gallbladder | Cancer | Matrilysin
Journal Article
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 06/2001, Volume 88, Issue 12, pp. 1291 - 1298
Diabetes mellitus (DM) is a primary risk factor for cardiovascular disease. Although recent studies have demonstrated an important role for extracellular... 
Oxidative stress | Gelatinase | Remodeling | Atherosclerosis | Endothelium | atherosclerosis | endothelium | remodeling | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | COLONY-STIMULATING FACTOR | MECHANISM | ANGIOGENESIS | NECROSIS-FACTOR-ALPHA | IN-VITRO | ENDOTHELIAL-CELLS | gelatinase | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | HEMATOLOGY | EXPRESSION | oxidative stress | ADHESION MOLECULE-1 VCAM-1 | Endothelium, Vascular - cytology | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | Diabetes Mellitus, Experimental - enzymology | Streptozocin | Oxidative Stress - physiology | Endothelium, Vascular - drug effects | Male | Insulin - blood | RNA, Messenger - metabolism | Matrix Metalloproteinase 9 - metabolism | Cattle | Matrix Metalloproteinase 9 - genetics | Aorta | Diabetes Mellitus, Experimental - chemically induced | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Promoter Regions, Genetic | Matrix Metalloproteinase 2 - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Blood Glucose | Glucose - pharmacology | Protein Kinase C - antagonists & inhibitors | Antioxidants - pharmacology | Macrophages - cytology | Muscle, Smooth, Vascular - cytology | Rats, Sprague-Dawley | Hyperglycemia - metabolism | Macrophages - metabolism | Animals | Endothelium, Vascular - metabolism | Glucose - metabolism | Macrophages - drug effects | Mice | Index Medicus
Journal Article