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Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 02/2018, Volume 150, pp. 137 - 143
A quantitative analysis of zinc endopeptidases matrix metalloproteinase 9 (MMP9) and matrix metalloproteinase 3 (MMP3) from human blood serum are presented.... 
Matrix metalloproteinase 3 | Human blood serum | Matrix metalloproteinase 9 | LC–MS/MS | ELISA | ANTIBODIES | CHEMISTRY, ANALYTICAL | QUANTIFICATION | QUANTITATION | TANDEM MASS-SPECTROMETRY | LC-MS/MS | BIOPHARMACEUTICAL PROTEINS | PEPTIDES | LIQUID-CHROMATOGRAPHY | BIOLOGICAL MATRICES | PHARMACOLOGY & PHARMACY | OSTEOARTHRITIS | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e20164 - e20164
Background: Diosgenin, a steroidal saponin obtained from fenugreek (Trigonella foenum graecum), was found to exert anti-carcinogenic properties, such as... 
APOPTOSIS | SIGNALING PATHWAYS | ACTIVATION | METASTASIS | ANGIOGENESIS | COLORECTAL-CANCER | KINASE | BIOLOGY | CYCLE ARREST | OSTEOSARCOMA CELLS | PROGRESSION | Prostatic Neoplasms - metabolism | Humans | Immunoblotting | JNK Mitogen-Activated Protein Kinases - metabolism | Male | NF-kappa B - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Tissue Inhibitor of Metalloproteinase-2 - genetics | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 7 - metabolism | Basigin - genetics | Matrix Metalloproteinase 9 - genetics | Polymerase Chain Reaction | JNK Mitogen-Activated Protein Kinases - genetics | Phosphatidylinositol 3-Kinase - metabolism | Diosgenin - pharmacology | Matrix Metalloproteinase 2 - metabolism | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase 7 - genetics | NF-kappa B - genetics | Phosphatidylinositol 3-Kinase - genetics | Basigin - metabolism | Cell Line, Tumor | Progesterone | Metastasis | Vascular endothelial growth factor | Health aspects | Prostate cancer | Apoptosis | Transcription factors | Boyden chamber | Matrix metalloproteinases | Leukocyte migration | AKT protein | Assaying | Metastases | Proteins | Angiogenesis | Cell growth | Gelatin | Inhibition | Enzymes | NF-κB protein | Medical technology | Wound healing | Gene expression | 1-Phosphatidylinositol 3-kinase | Pharmacy | Cell migration | Cell proliferation | Biotechnology | Tissue inhibitor of metalloproteinases | Phosphorylation | Colorectal cancer | Science | mRNA | Matrix metalloproteinase | Kinases | Cell adhesion & migration | Carcinogens | Cell cycle | Fenugreek | Metalloproteinase | Tumor cells | Extracellular signal-regulated kinase | c-Jun protein | Breast cancer | Endothelial cells | Gelatinase B | Gelatinase A | Signaling | Collagen | Prostate | Tumors | Cancer | Index Medicus
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 03/2017, Volume 101, Issue 3, pp. 775 - 783
Synovial IL‐21 + TNF + CD4 + T cells induce matrix metalloproteinase production by fibroblast‐like synoviocytes in RA patients. Bone and cartilage destruction... 
peripheral blood | autoimmune | inflammation | synovial fluid | Synovial fluid | Autoimmune | Inflammation | Peripheral blood | ACTIVATION | RECEPTOR | CLASSIFICATION | INTERLEUKIN-21 | IMMUNOLOGY | IL-21 | CELL BIOLOGY | B-CELLS | CYTOKINE PRODUCTION | FOLLICULAR-HELPER-CELLS | HEMATOLOGY | EXPRESSION | TH17 CELLS | Tumor Necrosis Factor-alpha - metabolism | Cell Proliferation | RANK Ligand - metabolism | Humans | Synovial Fluid - metabolism | Interferon-gamma - metabolism | Interleukins - metabolism | Peptides, Cyclic - metabolism | CD4-Positive T-Lymphocytes - immunology | Immunoglobulin M - metabolism | Synoviocytes - metabolism | Psoriasis - pathology | T-Lymphocytes, Helper-Inducer - immunology | Proto-Oncogene Proteins c-bcl-6 - metabolism | Interleukin-6 - metabolism | Psoriasis - immunology | Rheumatoid Factor - metabolism | Joints - pathology | Matrix Metalloproteinase 3 - metabolism | Fibroblasts - pathology | T-Box Domain Proteins - metabolism | Arthritis, Rheumatoid - pathology | Interleukin-17 - metabolism | Biopsy | Arthritis, Rheumatoid - immunology | Matrix Metalloproteinase 1 - metabolism | Immunoglobulin M | Destruction | Antibodies | Lymphocytes T | Arthritis | Matrix metalloproteinase | Cartilage | Lymphocytes | Interleukin 21 | Fibroblasts | Metalloproteinase | Interstitial collagenase | Stromelysin 1 | Secretion | Citrulline | Patients | Synoviocytes | CD4 antigen | Rheumatoid factor | Tumor necrosis factor | Rheumatoid arthritis | Health risk assessment | Neutralization | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 06/2010, Volume 29, Issue 25, pp. 3619 - 3629
Aneurysmal bone cyst (ABC) is an aggressive, pediatric bone tumor characterized by extensive destruction of the surrounding bone. Although first described over... 
NF-κB | aneurysmal bone cyst | TRE17/USP6 | MMP-9 | Arf6 | RhoA | DEUBIQUITINATING ENZYME | CARCINOMA CELLS | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-SITU HYBRIDIZATION | CELL BIOLOGY | STROMELYSIN-2 MMP-10 | NF-kappa B | ONCOLOGY | PATHWAY | GENETICS & HEREDITY | CDC42 GTPASES | MATRIX-METALLOPROTEINASE-9 EXPRESSION | RHO-GTPASES | ENDOTHELIAL GROWTH-FACTOR | USP6 | NFκB | TRE17
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, pp. e42714 - e42714
The hormone, relaxin, inhibits aberrant myofibroblast differentiation and collagen deposition by disrupting the TGF-beta 1/Smad2 axis, via its cognate... 
RENAL FIBROSIS | LUNG FIBROSIS | COLLAGEN | MULTIDISCIPLINARY SCIENCES | GROWTH | INTERSTITIAL FIBROSIS | TISSUE INHIBITORS | SMOOTH-MUSCLE-CELLS | NITRIC-OXIDE PATHWAY | HORMONE RELAXIN | FIBROBLASTS | Relaxin - metabolism | Matrix Metalloproteinases - genetics | Receptors, G-Protein-Coupled - metabolism | Humans | Male | Receptors, Peptide - genetics | Matrix Metalloproteinase 9 - metabolism | Relaxin - genetics | Matrix Metalloproteinase 9 - genetics | Fibroblasts - metabolism | Cell Line | Matrix Metalloproteinase 2 - metabolism | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Rats | Kidney - cytology | Signal Transduction - genetics | Extracellular Signal-Regulated MAP Kinases | Rats, Sprague-Dawley | Matrix Metalloproteinase 13 - metabolism | Mice, Knockout | Matrix Metalloproteinase 2 - genetics | Animals | Cyclic GMP - metabolism | Nitric Oxide Synthase Type I - metabolism | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Nitric Oxide Synthase Type I - genetics | Receptors, G-Protein-Coupled - genetics | Matrix Metalloproteinases - metabolism | Nitric Oxide - metabolism | Receptors, Peptide - metabolism | Physiological aspects | Genetic aspects | Research | Transforming growth factors | Metalloenzymes | Nitric oxide | Neurosciences | Phosphorylation | Matrix metalloproteinases | Guanosine | Smooth muscle | Genomes | Arthritis | Biochemistry | Matrix metalloproteinase | Guanylate cyclase | Western blotting | Signal transduction | Arginine | Gelatin | Rodents | Cyclic GMP | Fibroblasts | Metalloproteinase | Interstitial collagenase | Kidneys | Extracellular signal-regulated kinase | Collagenase 3 | Nitric-oxide synthase | Gelatinase B | NG-Nitroarginine methyl ester | Gelatinase A | Signaling | Inhibitors | Human performance | Collagen | Isoforms | Fibrosis | Skin | Aberration | Molecular biology | Ornithine | Index Medicus
Journal Article
Stroke, ISSN 0039-2499, 1998, Volume 29, Issue 5, pp. 1020 - 1030
Background and Purpose-Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade the extracellular matrix and are implicated in... 
Antibody inhibition | Endothelium, vascular |