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Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 10/2006, Volume 20, Issue 19, pp. 2673 - 2686
Carcinoma cells initiate the metastatic cascade by inserting invasive pseudopodia through breaches in the basement membrane (BM), a specialized barrier of... 
Matrix metalloproteinases | MT-MMPs | Type IV collagen | Invasion | Basement membrane | Cancer | COVALENT CROSS-LINK | ACTIVATION | basement membrane | COLLAGEN-IV | type IV collagen | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | MT1-MMP | INVASIVE GROWTH | invasion | GELATINASE-A | EPITHELIUM | GENETICS & HEREDITY | cancer | EXTRACELLULAR-MATRIX | TRIPLE HELICASE ACTIVITIES | matrix metalloproteinases | Neoplasms - metabolism | RNA, Small Interfering - genetics | Basement Membrane - ultrastructure | Humans | Matrix Metalloproteinase 15 - genetics | Cercopithecus aethiops | Extracellular Matrix - metabolism | Cell Movement - physiology | Matrix Metalloproteinase 16 - genetics | Neoplasms - physiopathology | Basement Membrane - enzymology | Collagen Type IV - metabolism | Cell Line | Microscopy, Electron, Transmission | Microscopy, Electron, Scanning | Matrix Metalloproteinase 15 - metabolism | Neoplasm Invasiveness | Matrix Metalloproteinase 16 - metabolism | Rats | Matrix Metalloproteinase 14 - metabolism | Matrix Metalloproteinases, Membrane-Associated - genetics | Mutation - genetics | Tissue Inhibitor of Metalloproteinases - metabolism | Extracellular Matrix - ultrastructure | Animals | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Basement Membrane - physiology | Mice | Matrix Metalloproteinases, Membrane-Associated - metabolism | Neoplasms - pathology | COS Cells | Antimitotic agents | Proteolysis | Collagen | Analysis | Physiological aspects | Membrane, Basement | Genetic aspects | Research | Antineoplastic agents | Structure | Index Medicus | Research Paper
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2006, Volume 26, Issue 43, pp. 10939 - 10948
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2011, Volume 286, Issue 38, pp. 33167 - 33177
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2016, Volume 291, Issue 21, pp. 11348 - 11358
The four tissue inhibitors of metalloproteinases (TIMPs) are potent inhibitors of the many matrixins (MMPs), except that TIMP1 weakly inhibits some MMPs,... 
SITE | calorimetry | COMPLEX | TIMP-1 | TERMINAL DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLEXIBILITY | thermodynamics | tissue inhibitor of metalloproteinase (TIMP) | CATALYTIC DOMAIN | conformational change | protein engineering | enzyme inhibitor | matrix metalloproteinase (MMP) | protein-protein interaction | zinc | BINDING | protein dynamic | HEAT-CAPACITY | ENTROPY | Recombinant Proteins - metabolism | Mutagenesis, Site-Directed | Humans | Matrix Metalloproteinase 14 - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Matrix Metalloproteinase 3 - metabolism | Recombinant Proteins - genetics | Matrix Metalloproteinase 14 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - genetics | Thermodynamics | Tissue Inhibitor of Metalloproteinase-1 - genetics | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - chemistry | Matrix Metalloproteinase 14 - genetics | Matrix Metalloproteinase 3 - chemistry | Protein Interaction Domains and Motifs | Matrix Metalloproteinase 1 - chemistry | Matrix Metalloproteinase 1 - metabolism | Matrix Metalloproteinase 3 - genetics | Tissue Inhibitor of Metalloproteinase-1 - chemistry | Matrix Metalloproteinase 1 - genetics | Index Medicus | Molecular Biophysics
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 03/2010, Volume 70, Issue 6, pp. 2224 - 2234
Journal Article
Journal of Cell Science, ISSN 0021-9533, 10/2011, Volume 124, Issue 19, pp. 3369 - 3380
Journal Article
CIRCULATION, ISSN 0009-7322, 06/1999, Volume 99, Issue 24, pp. 3103 - 3109
Background-Matrix metalloproteinases (MMPs) are expressed in atherosclerotic plaques, where in their active form, they may contribute to vascular remodeling... 
LOCALIZATION | COMPLEX | CARDIAC & CARDIOVASCULAR SYSTEMS | metalloproteinases | RELEASE | STROMELYSIN GENE-EXPRESSION | LESIONS | IV COLLAGENASE | CAROTID ARTERIES | cells | proteins | SURFACE | PERIPHERAL VASCULAR DISEASE | EXTRACELLULAR-MATRIX | HEMATOLOGY | lipoproteins | SMOOTH-MUSCLE CELLS | Metalloendopeptidases - genetics | Gene Expression Regulation, Enzymologic - drug effects | Macrophages - chemistry | Coronary Vessels - chemistry | Humans | RNA, Messenger - analysis | Metalloendopeptidases - metabolism | Gelatinases - analysis | Flow Cytometry | Matrix Metalloproteinases, Membrane-Associated | Inflammation Mediators - metabolism | Lipoproteins - metabolism | Saphenous Vein - cytology | Metalloendopeptidases - analysis | Gelatinases - immunology | Coronary Vessels - enzymology | Matrix Metalloproteinase 2 | Cells, Cultured | Tissue Inhibitor of Metalloproteinase-2 - analysis | Lipoproteins, LDL - pharmacology | Gelatinases - biosynthesis | Antibodies, Monoclonal | Metalloendopeptidases - immunology | Muscle, Smooth, Vascular - cytology | Interleukin-1 - pharmacology | Macrophages - enzymology | Metalloendopeptidases - biosynthesis | Tumor Necrosis Factor-alpha - pharmacology | Blotting, Northern | Enzyme Precursors - metabolism | Muscle, Smooth, Vascular - pathology | Arteriosclerosis - metabolism | Gene Expression Regulation, Enzymologic - immunology | Arteriosclerosis - pathology | Muscle, Smooth, Vascular - enzymology | Tissue Inhibitor of Metalloproteinase-2 - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2009, Volume 9, Issue 1, pp. 20 - 20
Background: The metastatic disease rather than the primary tumor itself is responsible for death in most solid tumors, including breast cancer. The role of... 
KAZAL MOTIFS | MATRIX METALLOPROTEINASES | LUNG-CANCER | IN-VITRO | CYSTEINE-RICH PROTEIN | ONCOLOGY | RT-PCR | EXTRACELLULAR-MATRIX | PROGNOSTIC-SIGNIFICANCE | CARCINOMA | RNA EXPRESSION | Matrix Metalloproteinases - genetics | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Humans | Membrane Glycoproteins - biosynthesis | GPI-Linked Proteins | Tissue Inhibitor of Metalloproteinase-2 - genetics | Breast Neoplasms - metabolism | Tissue Inhibitor of Metalloproteinases - genetics | Matrix Metalloproteinase 14 - biosynthesis | RNA, Messenger - biosynthesis | Breast Neoplasms - enzymology | Neoplasm Metastasis | Matrix Metalloproteinase 9 - genetics | Tissue Inhibitor of Metalloproteinase-2 - biosynthesis | Matrix Metalloproteinase 2 - biosynthesis | Tissue Inhibitor of Metalloproteinases - biosynthesis | Matrix Metalloproteinases - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Neoplasm Invasiveness | RNA, Messenger - genetics | Reverse Transcriptase Polymerase Chain Reaction | Membrane Glycoproteins - genetics | Matrix Metalloproteinase 2 - genetics | Tissue Inhibitor of Metalloproteinase-1 - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Care and treatment | Prognosis | Enzyme inhibitors | Proteases | Breast cancer | Genetic aspects | Dosage and administration | Research | Gene expression | Health aspects | Index Medicus
Journal Article