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Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 44, pp. 18052 - 18061
The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of protein synthesis and potential target for modifying cellular metabolism in... 
autophagy | mechanistic target of rapamycin (mTOR) | RAG GTPASES | amino acid | BIOCHEMISTRY & MOLECULAR BIOLOGY | mammalian target of rapamycin (mTOR) | RAGULATOR | CANCER | dynamin | GROWTH | DYNASORE | endocytosis | REQUIRES | PROTEINS | INHIBITOR | mTORC1 | SUFFICIENCY | Humans | Cytoplasm - metabolism | Ras Homolog Enriched in Brain Protein - genetics | Protein Transport - drug effects | Ras Homolog Enriched in Brain Protein - metabolism | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Amino Acids - metabolism | Mechanistic Target of Rapamycin Complex 1 - genetics | Lysosomes - metabolism | Membrane Transport Modulators - pharmacology | HEK293 Cells | Dynamin II - metabolism | Biomarkers - metabolism | Lysosomes - drug effects | Endocytosis - drug effects | Enzyme Inhibitors - pharmacology | Dynamin II - genetics | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Monomeric GTP-Binding Proteins - genetics | Enzyme Activation - drug effects | Clathrin - metabolism | Mechanistic Target of Rapamycin Complex 1 - metabolism | Dynamin II - antagonists & inhibitors | Clathrin - antagonists & inhibitors | Mechanistic Target of Rapamycin Complex 1 - agonists | Monomeric GTP-Binding Proteins - metabolism | Mutation | Cytoplasm - drug effects | Microscopy, Fluorescence | Amino Acid Substitution | Index Medicus | Cell Biology
Journal Article
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, pp. 1 - 19
Journal Article
Nature, ISSN 0028-0836, 10/2017, Volume 550, Issue 7675, pp. 265 - 269
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 44, pp. 17229 - 17239
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 45, pp. 18443 - 18456
Cardiac hypertrophy is closely linked to impaired fatty acid oxidation, but the molecular basis of this link is unclear. Here, we investigated the loss of an... 
MORTALITY | TARGET | PATHOLOGICAL HYPERTROPHY | cardiac metabolism | BIOCHEMISTRY & MOLECULAR BIOLOGY | mammalian target of rapamycin (mTOR) | HDAC INHIBITION | FAILURE | LEFT-VENTRICULAR HYPERTROPHY | DIASTOLIC DYSFUNCTION | acetylation | METABOLISM | FATTY-ACID OXIDATION | fatty acid oxidation | cardiac hypertrophy | CORONARY-HEART-DISEASE | Carnitine O-Palmitoyltransferase - genetics | Mitochondria, Heart - metabolism | Mitochondria, Heart - pathology | Atrial Remodeling - drug effects | Cardiomegaly - etiology | Male | Metabolism, Inborn Errors - therapy | Mitochondria, Heart - drug effects | Protein Processing, Post-Translational - drug effects | Carnitine O-Palmitoyltransferase - metabolism | Myocardium - metabolism | Carnitine O-Palmitoyltransferase - deficiency | Drug Resistance | Heart - physiopathology | Sirolimus - therapeutic use | Specific Pathogen-Free Organisms | Diet, Ketogenic | Metabolism, Inborn Errors - metabolism | Mice, Transgenic | Myocardium - pathology | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Enzyme Activation - drug effects | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mice, Knockout | Acetylation - drug effects | Myocardium - enzymology | Animals | Cardiomegaly - prevention & control | Protein Kinase Inhibitors - therapeutic use | Survival Analysis | Heart - drug effects | Histone Deacetylase Inhibitors - therapeutic use | Metabolism, Inborn Errors - pathology | Metabolism, Inborn Errors - physiopathology | Crosses, Genetic | Index Medicus | Lipids
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 21, pp. E4261 - E4270
Journal Article
Journal Article