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1. Full Text A Mechanistic Study to Determine the Structural Similarities Between Artificial Membrane Strat-M™ and Biological Membranes and Its Application to Carry Out Skin Permeation Study of Amphotericin B Nanoformulations
by Kaur, Lakhvir and Singh, Kanwaldeep and Paul, Surinder and Singh, Sukhprit and Singh, Shashank and Jain, Subheet Kumar
AAPS PharmSciTech, ISSN 1530-9932, 5/2018, Volume 19, Issue 4, pp. 1606 - 1624
Biochemistry, general | Biotechnology | Biomedicine | BET analysis | Pharmacy | Similarity factor analysis | Human skin | Mechanistic study | Pharmacology/Toxicology | Surface analysis | Dermatophytosis | Strat-M | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Amphotericin B | Antiparasitic agents | Skin | Index Medicus
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2. Full Text Experimental and Computational Studies on Remote γ‑C(sp3)–H Silylation and Germanylation of Aliphatic Carboxamides
by Deb, Arghya and Singh, Sukriti and Seth, Kapileswar and Pimparkar, Sandeep and Bhaskararao, Bangaru and Guin, Srimanta and Sunoj, Raghavan B and Maiti, Debabrata
ACS catalysis, ISSN 2155-5435, 12/2017, Volume 7, Issue 12, pp. 8171 - 8175
germanylation | organopalladium crystal | mechanistic studies | DFT | silylation | γ-C-H activation | Physical Sciences | Chemistry | Chemistry, Physical | Science & Technology
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3. Full Text Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Three‐Year Results From the Randomized SCHEDULE Study
by Andreassen, A. K and Andersson, B and Gustafsson, F and Eiskjær, H and Rådegran, G and Gude, E and Jansson, K and Solbu, D and Karason, K and Arora, S and Dellgren, G and Gullestad, L and SCHEDULE Investigators and SCHEDULE investigators and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
American journal of transplantation, ISSN 1600-6135, 04/2016, Volume 16, Issue 4, pp. 1238 - 1247
practice | immune | mechanistic target of rapamycin (mTOR) | clinical research | heart transplantation | mechanistic target of rapamycin: everolimus | immunosuppressant | clinical trial modulation | cardiology, immunosuppression | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Prognosis | Prospective Studies | Follow-Up Studies | Vascular Diseases - etiology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Transplant Recipients | Kidney Function Tests | Young Adult | Allografts | Adult | Everolimus - therapeutic use | Female | Postoperative Complications | Vascular Diseases - drug therapy | Glomerular Filtration Rate | Graft Rejection - prevention & control | Risk Factors | Graft Rejection - etiology | Heart Transplantation | Graft Rejection - diagnosis | Withholding Treatment | Vascular Diseases - diagnosis | Cyclosporine - therapeutic use | Calcineurin Inhibitors - therapeutic use | Adolescent | Aged | Graft Survival - drug effects | Heart Diseases - surgery | Heart | Analysis | Organ transplant recipients | Mycophenolate mofetil | Cyclosporine | Angiogenesis inhibitors | Transplants & implants | Health risk assessment | Multivariate analysis | Index Medicus | Kardiologi | Cardiac and Cardiovascular Systems | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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4. Full Text Two‐year outcomes in de novo renal transplant recipients receiving everolimus‐facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study
by Berger, Stefan P and Sommerer, Claudia and Witzke, Oliver and Tedesco, Helio and Chadban, Steve and Mulgaonkar, Shamkant and Qazi, Yasir and Fijter, Johan W and Oppenheimer, Federico and Cruzado, Josep M and Watarai, Yoshihiko and Massari, Pablo and Legendre, Christophe and Citterio, Franco and Henry, Mitchell and Srinivas, Titte R and Vincenti, Flavio and Gutierrez, Maria Pilar Hernandez and Marti, Ana Maria and Bernhardt, Peter and Pascual, Julio and TRANSFORM Investigators and TRANSFORM investigators and the TRANSFORM investigators
American journal of transplantation, ISSN 1600-6135, 11/2019, Volume 19, Issue 11, pp. 3018 - 3034
immunosuppressive regimens ‐ minimization/withdrawal | immunosuppressant ‐ mechanistic target of rapamycin (mTOR) | immunosuppression/immune modulation | clinical research/practice | kidney transplantation/nephrology | immunosuppressant ‐ mechanistic target of rapamycin: everolimus | liver transplantation/hepatology | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Virus diseases | Kidneys | Organ transplant recipients | Cytomegalovirus infections | Health aspects | Immunosuppressive agents | Cytomegalovirus | Mycophenolic acid | Epidermal growth factor receptors | Transplants & implants | Biopsy | Calcineurin | Calcineurin inhibitors | Health risk assessment | Glomerular filtration rate | Graft rejection | Kidney transplantation | Index Medicus
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5. Full Text DFT mechanistic study on tandem sequential [4 + 2]/[3 + 2] addition reaction of cyclooctatetraene with functionalized acetylenes and nitrile imines
by Opoku, Ernest and Tia, Richard and Adei, Evans
Journal of physical organic chemistry, ISSN 0894-3230, 10/2019, Volume 32, Issue 10, p. n/a
pyrazole | tandem addition | pyrazoline | cyclooctatetraene | mechanistic study | nitrile imine | Physical Sciences | Chemistry | Chemistry, Organic | Chemistry, Physical | Science & Technology | Density functionals | Schiff bases | Pyrolysis | Analysis | Acetylene | Cycloaddition | Dipoles | Imines | Molecular orbitals | Density functional theory | Activation | Selectivity | Cyclobutane | Perturbation | Adducts | Alkynes
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6. Full Text Statistical testing in electrophysiological studies
by Maris, E.G.G
Psychophysiology, ISSN 0048-5772, 2012, Volume 49, Issue 4, pp. 549 - 565
Statistical test | Common pick‐up | Permutation test | Electrophysiology | Bootstrap | Neyman‐Pearson | Mechanistic evidence | Neurobiological data | Bayesian inference | Multiple comparisons problem | Neyman-Pearson | Common pick-up | Psychology, Biological | Psychology, Experimental | Neurosciences | Social Sciences | Life Sciences & Biomedicine | Psychology | Physiology | Neurosciences & Neurology | Science & Technology | Data Interpretation, Statistical | Reproducibility of Results | Algorithms | Analysis of Variance | Bayes Theorem | Electrophysiology - statistics & numerical data | Probability | Physiological psychology | Electroencephalography | Statistical methods | Statistical analysis | Electrophysiological recording | Data processing | Decision making | Bayesian analysis | Statistics | Index Medicus
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7. Full Text Five‐Year Outcomes in Kidney Transplant Patients Converted From Cyclosporine to Everolimus: The Randomized ZEUS Study
by Budde, K and Lehner, F and Sommerer, C and Reinke, P and Arns, W and Eisenberger, U and Wüthrich, R. P and Mühlfeld, A and Heller, K and Porstner, M and Veit, J and Paulus, E.‐M and Witzke, O and ZEUS Study Investigators
American journal of transplantation, ISSN 1600-6135, 01/2015, Volume 15, Issue 1, pp. 119 - 128
nephrology | practice | mechanistic target of rapamycin (mTOR) | kidney transplantation | mechanistic target of rapamycin: everolimus | Clinical research | immunosuppressant | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Graft Survival - immunology | Prognosis | Follow-Up Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Transplant Recipients | Kidney Function Tests | Young Adult | Adult | Female | Everolimus | Postoperative Complications | Graft Rejection - drug therapy | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Glomerular Filtration Rate | Kidney Failure, Chronic - surgery | Risk Factors | Kidney Transplantation | Cyclosporine - therapeutic use | Adolescent | Kidney Failure, Chronic - complications | Aged | Graft Rejection - immunology | Graft Survival - drug effects | Research Design | Medical research | Kidneys | Analysis | Patient outcomes | Medicine, Experimental | Organ transplant recipients | Angiogenesis inhibitors | Transplants & implants | Drug therapy | Index Medicus
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8. Full Text Simultaneous disinfection of E. faecalis and degradation of carbamazepine by sulfate radicals: An experimental and modelling study
by Liu, Kai and Bai, Lu and Shi, Yan and Wei, Zongsu and Spinney, Richard and Göktaş, Recep Kaya and Dionysiou, Dionysios D and Xiao, Ruiyang
Environmental pollution (1987), ISSN 0269-7491, 08/2020, Volume 263, p. 114558
Mechanistic model | Micropollutant | Disinfection | Sulfate radical | Microorganism | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences
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9. Full Text First-in-human pharmacokinetic and pharmacodynamic study of the dual m-TORC 1/2 inhibitor AZD2014
by Basu, Bristi and Dean, Emma and Puglisi, Martina and Greystoke, Alastair and Ong, Michael and Burke, Wendy and Cavallin, Maria and Bigley, Graham and Womack, Christopher and Harrington, Elizabeth A and Green, Stephen and Oelmann, Elisabeth and De Bono, Johann S and Ranson, Malcolm and Banerji, Udai
Clinical cancer research, ISSN 1078-0432, 08/2015, Volume 21, Issue 15, pp. 3412 - 3419
Life Sciences & Biomedicine | Oncology | Science & Technology | Administration, Oral | Humans | Middle Aged | Morpholines - administration & dosage | Male | Mechanistic Target of Rapamycin Complex 2 | Drug-Related Side Effects and Adverse Reactions - pathology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | Neoplasms - drug therapy | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Adult | Female | Aged | Morpholines - pharmacokinetics | Neoplasms - pathology | Morpholines - adverse effects | Index Medicus | pharmacokinetics | Phase I | m-TORC2 inhibitor | pharmacodynamics | m-TORC1 inhibitor
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10. Full Text Mechanistic study of glycerol dehydration on Brønsted acidic amorphous aluminosilicate
by Yun, Danim and Yun, Yang Sik and Kim, Tae Yong and Park, Hongseok and Lee, Jong Min and Han, Jeong Woo and Yi, Jongheop
Journal of catalysis, ISSN 0021-9517, 09/2016, Volume 341, pp. 33 - 43
Brønsted acid sites | Glycerol dehydration | Mechanistic study | Aluminosilicate | Density functional theory (DFT) calculation | Engineering | Physical Sciences | Engineering, Chemical | Chemistry | Technology | Chemistry, Physical | Science & Technology | Glycerin | Glycerol | Dehydration (Physiology) | Chemical reactions | Catalysts | Dehydration
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