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American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2015, Volume 308, Issue 4, pp. L344 - L357
Pathological fibrosis is driven by a feedback loop in which the fibrotic extracellular matrix is both a cause and consequence of fibroblast activation.... 
Plasminogen activator inhibitor 1 | Extracellular matrix | Mechanotransduction | Hippo | Idiopathic pulmonary fibrosis | LUNG | DOMAIN | PHYSIOLOGY | mechanotransduction | HIPPO PATHWAY | idiopathic pulmonary fibrosis | TRANSCRIPTIONAL COACTIVATOR | plasminogen activator inhibitor 1 | GROWTH-FACTOR-BETA | MECHANICAL MEMORY | MATRIX STIFFNESS | INHIBITION | RESPIRATORY SYSTEM | DIFFERENTIATION | IDIOPATHIC PULMONARY-FIBROSIS | extracellular matrix | NIH 3T3 Cells | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Pulmonary Fibrosis - genetics | Phosphoproteins - metabolism | Serpin E2 - biosynthesis | Gene Knockdown Techniques | Female | Lung - metabolism | Pulmonary Fibrosis - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Intracellular Signaling Peptides and Proteins - genetics | Mechanotransduction, Cellular - genetics | Fibroblasts - metabolism | Lung - pathology | Pulmonary Fibrosis - pathology | Phosphoproteins - genetics | Fibroblasts - pathology | Plasminogen Activator Inhibitor 1 - biosynthesis | Serpin E2 - genetics | Animals | Transforming Growth Factor beta - genetics | Adaptor Proteins, Signal Transducing - genetics | Mice, Inbred NOD | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Transforming Growth Factor beta - metabolism | Transcriptional coactivators | Fibroblasts | Genetic aspects | Pulmonary fibrosis | Health aspects | Oncogenes | Bone morphogenetic proteins | Fibrosis | Signal transduction | Pathology | Cellular biology | Protein expression | Biosynthesis | Physiology | Binding sites | Index Medicus | Call for Papers
Journal Article
Neuron, ISSN 0896-6273, 08/2013, Volume 79, Issue 3, pp. 504 - 515
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2015, Volume 112, Issue 24, pp. 7563 - 7568
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4796 - 4809
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2008, Volume 118, Issue 12, pp. 3870 - 3880
Journal Article
Oncogene, ISSN 0950-9232, 12/2009, Volume 28, Issue 49, pp. 4326 - 4343
Mammographically dense breast tissue is one of the greatest risk factors for developing breast carcinoma, yet the associated molecular mechanisms remain... 
3D matrix/focal adhesion | Breast cancer | Mechanotransduction | Epithelial morphogenesis | Cell-extracellular matrix interaction | Breast tissue density | CANCER RISK | ACTIVATED PROTEIN-KINASE | mechanotransduction | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | MALIGNANT PHENOTYPE | CARCINOMA IN-SITU | CELL BIOLOGY | MAMMOGRAPHIC DENSITY | STRESS FIBERS | ONCOLOGY | epithelial morphogenesis | EPITHELIAL-SPECIFIC DISRUPTION | GROWTH-FACTORS | GENETICS & HEREDITY | EXTRACELLULAR-MATRIX | FOCAL ADHESION KINASE | breast tissue density | cell-extracellular matrix interaction | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Cell Count | Humans | Breast Neoplasms - etiology | Gene Expression Profiling | Extracellular Signal-Regulated MAP Kinases - metabolism | Mammary Glands, Human - metabolism | Mechanotransduction, Cellular - physiology | Carcinoma - etiology | Extracellular Matrix - chemistry | Breast Neoplasms - metabolism | Cell Transformation, Neoplastic - genetics | Extracellular Matrix - physiology | Gene Expression - physiology | Female | Mammary Glands, Human - physiology | Extracellular Signal-Regulated MAP Kinases - physiology | Focal Adhesion Kinase 1 - metabolism | Mechanotransduction, Cellular - genetics | Mammary Glands, Human - cytology | Risk Factors | Cells, Cultured | Focal Adhesion Kinase 1 - physiology | Cell Transformation, Neoplastic - metabolism | Phenotype | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Protein kinases | Risk factors | Genotype & phenotype | Cellular biology | Index Medicus | 3D-Matrix | Focal Adhesion | Cell-Extracellular Matrix Interaction | Epithelial Morphogenesis | Breast Cancer | Breast Tissue Density | Tumor-Stroma Interaction
Journal Article