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Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7539, pp. 376 - 380
The conserved co-activator complex Mediator enables regulated transcription irntiation by RNA polymerase (Pol) II. Here we reconstitute an active 15-subunit... 
STRUCTURAL BASIS | TFIIB COMPLEX | MULTIDISCIPLINARY SCIENCES | CHEMICAL CROSS-LINKING | CRYO-EM | ELECTRON-MICROSCOPY | SACCHAROMYCES-CEREVISIAE | MIDDLE MODULE | MASS-SPECTROMETRY | TRANSCRIPTION PREINITIATION COMPLEX | HEAD MODULE | Phosphorylation | Transcription Factor TFIIB - metabolism | Mediator Complex - metabolism | Transcription Factor TFIIB - chemistry | Allosteric Regulation | RNA Polymerase II - ultrastructure | Saccharomyces cerevisiae - ultrastructure | Transcription Factor TFIIH - chemistry | RNA Polymerase II - metabolism | Protein Subunits - metabolism | Mediator Complex - chemistry | Mediator Complex - ultrastructure | Protein Stability | Transcription Initiation, Genetic | Binding Sites | RNA Polymerase II - chemistry | Protein Structure, Tertiary | Saccharomyces cerevisiae Proteins - ultrastructure | Models, Molecular | DNA - metabolism | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | DNA - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Transcription Factor TFIIH - metabolism | Protein Subunits - chemistry | Enzyme Activation | Saccharomyces cerevisiae Proteins - chemistry | Physiological aspects | Protein research | Genetic transcription | Research | RNA polymerases | Transcription factors | Yeast | Microscopy | RNA polymerase | Kinases | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 02/2013, Volume 494, Issue 7438, pp. 497 - 501
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7500, pp. 376 - 380
Journal Article
Cell, ISSN 0092-8674, 06/2013, Volume 153, Issue 6, pp. 1281 - 1295
Journal Article
Cell, ISSN 0092-8674, 08/2015, Volume 162, Issue 5, pp. 1016 - 1028
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 04/2013, Volume 14, Issue 4, pp. 327 - 336
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 328 - 337
The Hippo/YAP signaling pathway is a crucial regulator of tissue growth, stem cell activity, and tumorigenesis. However, the mechanism by which YAP controls... 
REGULATOR | COACTIVATOR | ACTIVATION | COMPLEX | CHROMATIN | YORKIE | MEDIATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIZE | CELL | REQUIREMENT | CELL BIOLOGY | Chromatin - metabolism | Mediator Complex - metabolism | Humans | Gene Expression Regulation, Neoplastic | Intracellular Signaling Peptides and Proteins - metabolism | Cholangiocarcinoma - metabolism | DNA Polymerase II - metabolism | Phosphoproteins - metabolism | Carcinogenesis - metabolism | Piperidines - pharmacology | Transcription, Genetic | Antineoplastic Agents - pharmacology | Flavonoids - pharmacology | Bile Duct Neoplasms - genetics | DNA Polymerase II - genetics | Intracellular Signaling Peptides and Proteins - genetics | Bile Duct Neoplasms - drug therapy | Chromatin - chemistry | Bile Duct Neoplasms - metabolism | Signal Transduction | Cyclin-Dependent Kinase 9 - genetics | Carcinogenesis - genetics | Mediator Complex - genetics | Mice, Transgenic | Phosphoproteins - genetics | Carcinogenesis - drug effects | Carcinogenesis - pathology | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Enhancer Elements, Genetic | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cholangiocarcinoma - genetics | Protein Binding | Cyclin-Dependent Kinase 9 - metabolism | Mice | Bile Duct Neoplasms - pathology | Adaptor Proteins, Signal Transducing - metabolism | Genetic aspects | Genetic transcription | Growth | Analysis | Genomics | Stem cells | Yuan (China) | Chromatin | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7314, pp. 430 - 435
Journal Article