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by Morrissy, A. Sorana and Garzia, Livia and Shih, David J. H and Zuyderduyn, Scott and Huang, Xi and Skowron, Patryk and Remke, Marc and Cavalli, Florence M. G and Ramaswamy, Vijay and Lindsay, Patricia E and Jelveh, Salomeh and Donovan, Laura K and Wang, Xin and Luu, Betty and Zayne, Kory and Li, Yisu and Mayoh, Chelsea and Thiessen, Nina and Mercier, Eloi and Mungall, Karen L and Ma, Yusanne and Tse, Kane and Zeng, Thomas and Shumansky, Karey and Roth, Andrew J. L and Shah, Sohrab and Farooq, Hamza and Kijima, Noriyuki and Holgado, Borja L and Lee, John J. Y and Matan-Lithwick, Stuart and Liu, Jessica and Mack, Stephen C and Manno, Alex and Michealraj, K. A and Nor, Carolina and Peacock, John and Qin, Lei and Reimand, Juri and Rolider, Adi and Thompson, Yuan Y and Wu, Xiaochong and Pugh, Trevor and Ally, Adrian and Bilenky, Mikhail and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Young and Chuah, Eric and Corbett, Richard D and Dhalla, Noreen and He, An and Lee, Darlene and Li, Haiyan I and Long, William and Mayo, Michael and Plettner, Patrick and Qian, Jenny Q and Schein, Jacqueline E and Tam, Angela and Wong, Tina and Birol, Inanc and Zhao, Yongjun and Faria, Claudia C and Pimentel, José and Nunes, Sofia and Shalaby, Tarek and Grotzer, Michael and Pollack, Ian F and Hamilton, Ronald L and Li, Xiao-Nan and Bendel, Anne E and Fults, Daniel W and Walter, Andrew W and Kumabe, Toshihiro and Tominaga, Teiji and Collins, V. Peter and Cho, Yoon-Jae and Hoffman, Caitlin and Lyden, David and Wisoff, Jeffrey H and Garvin, James H and Stearns, Duncan S and Massimi, Luca and Schüller, Ulrich and Sterba, Jaroslav and Zitterbart, Karel and Puget, Stephanie and Ayrault, Olivier and Dunn, Sandra E and Tirapelli, Daniela P. C and Carlotti, Carlos G and Wheeler, Helen and Hallahan, Andrew R and Ingram, Wendy and MacDonald, Tobey J and Olson, Jeffrey J and Van Meir, Erwin G and Lee, Ji-Yeoun and Wang, Kyu-Chang and ...
Nature (London), ISSN 1476-4687, 2016, Volume 529, Issue 7586, pp. 351 - 357
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related... 
HETEROGENEITY | CANCER EVOLUTION | CELLS | IMPACT | MULTIDISCIPLINARY SCIENCES | SUBGROUP MEDULLOBLASTOMA | DYNAMICS | MUTATIONS | SEQUENCING DATA | LYMPHOBLASTIC-LEUKEMIA | GENOME | Clone Cells - drug effects | Humans | Male | Medulloblastoma - therapy | Radiotherapy, Image-Guided | Selection, Genetic - drug effects | Drosophila melanogaster - genetics | Neoplasm Recurrence, Local - pathology | Medulloblastoma - radiotherapy | DNA Mutational Analysis | Medulloblastoma - pathology | Female | Medulloblastoma - surgery | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Molecular Targeted Therapy - methods | Disease Models, Animal | Signal Transduction | Neoplasm Recurrence, Local - therapy | Drosophila melanogaster - cytology | Cerebellar Neoplasms - genetics | Clone Cells - metabolism | Genome, Human - genetics | Xenograft Model Antitumor Assays | Animals | Clone Cells - pathology | Craniospinal Irradiation | Neoplasm Recurrence, Local - genetics | Mice | Cerebellar Neoplasms - therapy | Cerebellar Neoplasms - surgery | Cerebellar Neoplasms - radiotherapy | Clonal selection theory | Care and treatment | Medulloblastoma | Oncology, Experimental | Genetic aspects | Research | Cancer | Genes | Cloning | Clinical trials | Cytotoxicity | Genomes | Radiation therapy | Metastasis | Cancer therapies | Rodents | Medical prognosis | Mutation | Tumors | Index Medicus
Journal Article
by Cavalli, Florence M.G and Remke, Marc and Rampasek, Ladislav and Peacock, John and Shih, David J.H and Luu, Betty and Garzia, Livia and Torchia, Jonathon and Nor, Carolina and Morrissy, A. Sorana and Agnihotri, Sameer and Thompson, Yuan Yao and Kuzan-Fischer, Claudia M and Farooq, Hamza and Isaev, Keren and Daniels, Craig and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Lee, Ji Yeoun and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Vasiljevic, Alexandre and Faure-Conter, Cecile and Jouvet, Anne and Giannini, Caterina and Nageswara Rao, Amulya A and Li, Kay Ka Wai and Ng, Ho-Keung and Eberhart, Charles G and Pollack, Ian F and Hamilton, Ronald L and Gillespie, G. Yancey and Olson, James M and Leary, Sarah and Weiss, William A and Lach, Boleslaw and Chambless, Lola B and Thompson, Reid C and Cooper, Michael K and Vibhakar, Rajeev and Hauser, Peter and van Veelen, Marie-Lise C and Kros, Johan M and French, Pim J and Ra, Young Shin and Kumabe, Toshihiro and López-Aguilar, Enrique and Zitterbart, Karel and Sterba, Jaroslav and Finocchiaro, Gaetano and Massimino, Maura and Van Meir, Erwin G and Osuka, Satoru and Shofuda, Tomoko and Klekner, Almos and Zollo, Massimo and Leonard, Jeffrey R and Rubin, Joshua B and Jabado, Nada and Albrecht, Steffen and Mora, Jaume and Van Meter, Timothy E and Jung, Shin and Moore, Andrew S and Hallahan, Andrew R and Chan, Jennifer A and Tirapelli, Daniela P.C and Carlotti, Carlos G and Fouladi, Maryam and Pimentel, José and Faria, Claudia C and Saad, Ali G and Massimi, Luca and Liau, Linda M and Wheeler, Helen and Nakamura, Hideo and Elbabaa, Samer K and Perezpeña-Diazconti, Mario and Chico Ponce de León, Fernando and Robinson, Shenandoah and Zapotocky, Michal and Lassaletta, Alvaro and Huang, Annie and Hawkins, Cynthia E and Tabori, Uri and Bouffet, Eric and Bartels, Ute and Dirks, Peter B and Rutka, James T and Bader, Gary D and Reimand, Jüri and Goldenberg, Anna and Ramaswamy, Vijay and Taylor, Michael D
Cancer cell, ISSN 1535-6108, 2017, Volume 31, Issue 6, pp. 737 - 754.e6
Journal Article
by Thompson, Eric M and Hielscher, Thomas and Bouffet, Eric and Remke, Marc and Luu, Betty and Gururangan, Sridharan and McLendon, Roger E and Bigner, Darell D and Lipp, Eric S and Perreault, Sebastien and Cho, Yoon-Jae and Grant, Gerald and Kim, Seung-Ki and Lee, Ji Yeoun and Rao, Amulya A Nageswara and Giannini, Caterina and Li, Kay Ka Wai and Ng, Ho-Keung and Yao, Yu and Kumabe, Toshihiro and Tominaga, Teiji and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Low, David C Y and Seow, Wan Tew and Chang, Kenneth T E and Mora, Jaume and Pollack, Ian F and Hamilton, Ronald L and Leary, Sarah and Moore, Andrew S and Ingram, Wendy J and Hallahan, Andrew R and Jouvet, Anne and Fèvre-Montange, Michelle and Vasiljevic, Alexandre and Faure-Conter, Cecile and Shofuda, Tomoko and Kagawa, Naoki and Hashimoto, Naoya and Jabado, Nada and Weil, Alexander G and Gayden, Tenzin and Wataya, Takafumi and Shalaby, Tarek and Grotzer, Michael and Zitterbart, Karel and Sterba, Jaroslav and Kren, Leos and Hortobágyi, Tibor and Klekner, Almos and László, Bognár and Pócza, Tímea and Hauser, Peter and Schüller, Ulrich and Jung, Shin and Jang, Woo-Youl and French, Pim J and Kros, Johan M and van Veelen, Marie-Lise C and Massimi, Luca and Leonard, Jeffrey R and Rubin, Joshua B and Vibhakar, Rajeev and Chambless, Lola B and Cooper, Michael K and Thompson, Reid C and Faria, Claudia C and Carvalho, Alice and Nunes, Sofia and Pimentel, José and Fan, Xing and Muraszko, Karin M and López-Aguilar, Enrique and Lyden, David and Garzia, Livia and Shih, David J H and Kijima, Noriyuki and Schneider, Christian and Adamski, Jennifer and Northcott, Paul A and Kool, Marcel and Jones, David T W and Chan, Jennifer A and Nikolic, Ana and Garre, Maria Luisa and Van Meir, Erwin G and Osuka, Satoru and Olson, Jeffrey J and Jahangiri, Arman and Castro, Brandyn A and Gupta, Nalin and Weiss, William A and Moxon-Emre, Iska and Mabbott, Donald J and Lassaletta, Alvaro and Hawkins, Cynthia E and Tabori, Uri and Drake, James and Kulkarni, Abhaya and ...
The lancet oncology, ISSN 1470-2045, 2016, Volume 17, Issue 4, pp. 484 - 495
Journal Article
Journal of neuro-oncology, ISSN 1573-7373, 2016, Volume 129, Issue 3, pp. 515 - 524
Journal Article
Acta neuropathologica, ISSN 1432-0533, 2012, Volume 123, Issue 4, pp. 473 - 484
Medulloblastoma is the most common malignant brain tumor in childhood. Molecular studies from several groups around the world demonstrated that medulloblastoma... 
Pathology | Neurosciences | Medicine & Public Health | Medulloblastoma | Pediatric brain tumor | Subgroups | Meta-analysis | PROFILES | SUBTYPES | DISTINCT | PATHOLOGY | NEUROSCIENCES | ADULT | CLINICAL NEUROLOGY | PEDIATRIC MEDULLOBLASTOMAS | BETA-CATENIN STATUS | CHILDHOOD MEDULLOBLASTOMA | Multivariate Analysis | Meta-Analysis as Topic | Age Distribution | Kv1.1 Potassium Channel - metabolism | Cerebellar Neoplasms - diagnosis | Humans | Transcriptome | Child, Preschool | Hedgehog Proteins - metabolism | Male | Gene Expression Profiling | Wnt Proteins - metabolism | Young Adult | Chromosomes, Human, Pair 3 | Wnt Proteins - genetics | Hedgehog Proteins - genetics | Microarray Analysis | Adult | Female | Retrospective Studies | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Child | Gene Expression Regulation, Neoplastic - physiology | Kv1.1 Potassium Channel - genetics | Receptors, Atrial Natriuretic Factor - metabolism | Medulloblastoma - diagnosis | International Cooperation | Cerebellar Neoplasms - genetics | Chromosomes, Human, Pair 17 | Adolescent | Chromosome Aberrations | Survival Analysis | Cytogenetics | Receptors, Atrial Natriuretic Factor - genetics | Medulloblastoma - classification | Cohort Studies | Immunohistochemistry | Demography | Wnt protein | Brain tumors | Data processing | Single-nucleotide polymorphism | Gene expression | Survival | Reviews | Hedgehog protein | DNA | Children | Original Paper
Journal Article
Acta neuropathologica, ISSN 1432-0533, 2014, Volume 128, Issue 1, pp. 137 - 149
Journal Article
Cancer cell, ISSN 1535-6108, 2016, Volume 29, Issue 4, pp. 508 - 522
The childhood brain tumor, medulloblastoma, includes four subtypes with very different prognoses. Here, we show that paracrine signals driven by mutant... 
LUNG-CANCER | ANGIOGENESIS | ONCOLOGY | PATHWAY | IN-VIVO | VINCRISTINE | TUMOR | CNS | CENTRAL-NERVOUS-SYSTEM | SUBGROUPS | CHEMOTHERAPY | CELL BIOLOGY | Humans | Neoplasm Proteins - physiology | Cerebellar Neoplasms - blood supply | Culture Media, Conditioned - pharmacology | Genetic Vectors - therapeutic use | Medulloblastoma - secretion | Recombinant Fusion Proteins - metabolism | Endothelium, Vascular - ultrastructure | Cerebellar Neoplasms - secretion | Wnt Proteins - genetics | Membrane Proteins - physiology | Pericytes - pathology | Glucose Transporter Type 1 - physiology | Antineoplastic Agents - pharmacokinetics | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Vincristine - pharmacokinetics | Disease Models, Animal | Carrier Proteins - physiology | Cerebellar Neoplasms - drug therapy | Transduction, Genetic | Genetic Association Studies | Genotype | Mice, Transgenic | Cerebellar Neoplasms - genetics | Tight Junctions - ultrastructure | Animals | Wnt Signaling Pathway - drug effects | Endothelium, Vascular - metabolism | Paracrine Communication - drug effects | Vincristine - therapeutic use | Medulloblastoma - blood supply | Mice | Wnt Proteins - physiology | Medulloblastoma - drug therapy | Drug Resistance, Neoplasm - physiology | Medulloblastoma - classification | Blood-Brain Barrier | Chemotherapy | Medulloblastoma | Brain tumors | Genetic aspects | Permeability | Cells | Cancer | Neurophysiology | Endothelium
Journal Article
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