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Journal of Inorganic Biochemistry, ISSN 0162-0134, 11/2013, Volume 128, pp. 85 - 96
Zinc(II) complexes of a non-steroidal anti-inflammatory drug, mefenamic acid(= Hmef) in the absence or presence of the nitrogen donor heterocyclic ligands... 
Antioxidant capacity | Zinc complexes | Interaction with calf-thymus DNA | Mefenamic acid | Interaction with serum albumins | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTICONVULSANT ACTIVITIES | CRYSTAL-STRUCTURES | STRUCTURAL-CHARACTERIZATION | BINDING PROPERTIES | CHEMISTRY, INORGANIC & NUCLEAR | COPPER(II) COMPLEXES | IN-VITRO | BIOLOGICAL EVALUATION | COBALT(II) COMPLEXES | METAL-COMPLEXES | Free Radical Scavengers - pharmacology | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Antioxidants - metabolism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Coordination Complexes - metabolism | Crystallography, X-Ray | Zinc - chemistry | Biphenyl Compounds - metabolism | Mefenamic Acid - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Lipoxygenase - metabolism | Zinc Compounds - metabolism | Biphenyl Compounds - antagonists & inhibitors | Lipoxygenase Inhibitors - chemistry | Zinc Compounds - pharmacology | Cattle | Mefenamic Acid - metabolism | Picrates - chemistry | Soybeans - enzymology | Coordination Complexes - pharmacology | Free Radicals - metabolism | Serum Albumin, Bovine - chemistry | Molecular Structure | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Biphenyl Compounds - chemistry | Serum Albumin - chemistry | Free Radical Scavengers - metabolism | Free Radicals - chemistry | Picrates - metabolism | Antioxidants - pharmacology | DNA - metabolism | Serum Albumin, Bovine - metabolism | Coordination Complexes - chemistry | Spectrophotometry, Ultraviolet | Zinc Compounds - chemistry | DNA - chemistry | Free Radicals - antagonists & inhibitors | Mefenamic Acid - pharmacology | Picrates - antagonists & inhibitors | Animals | Lipoxygenase Inhibitors - metabolism | Kinetics | Lipoxygenase Inhibitors - pharmacology | Serum Albumin - metabolism | Proteins | Antioxidants | Drug interactions | DNA | Genetic research | Nonsteroidal anti-inflammatory drugs | Protein binding
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 07/2016, Volume 160, pp. 125 - 139
Cobalt(II) complexes with a series of non-steroidal anti-inflammatory drugs (diflunisal, flufenamic acid, mefenamic acid and niflumic acid) in the presence of... 
Cobalt(II) complexes | Interaction with calf-thymus DNA | Interaction with albumins | Antioxidant activity | Non-steroidal anti-inflammatory drugs | MEFENAMIC-ACID | TRANSITION-METAL-COMPLEXES | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINUCLEAR COPPER(II) COMPLEX | DNA-BINDING PROPERTIES | CHEMISTRY, INORGANIC & NUCLEAR | TOLFENAMIC ACID STRUCTURE | FLUFENAMIC ACID | BIOLOGICAL EVALUATION | SCHIFF-BASE COMPLEXES | Free Radical Scavengers - chemistry | 2,2'-Dipyridyl - analogs & derivatives | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Crystallography, X-Ray | Mefenamic Acid - chemistry | Aminopyridines - chemistry | Biphenyl Compounds - antagonists & inhibitors | Phenanthrolines - chemistry | Picrates - chemistry | Free Radical Scavengers - chemical synthesis | Biphenyl Compounds - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Intercalating Agents - chemical synthesis | Methanol - chemistry | Serum Albumin - chemistry | Binding Sites | Niflumic Acid - chemistry | 2,2'-Dipyridyl - chemistry | Models, Molecular | Coordination Complexes - chemistry | Intercalating Agents - chemistry | DNA - chemistry | Diflunisal - chemistry | Picrates - antagonists & inhibitors | Cations, Divalent | Flufenamic Acid - chemistry | Coordination Complexes - chemical synthesis | Kinetics | Cobalt - chemistry
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43965
Aldo-keto reductase 1C3 (AKR1C3) catalyses the NADPH dependent reduction of carbonyl groups in a number of important steroid and prostanoid molecules. The... 
POTENT INHIBITOR | CYCLOOXYGENASE INHIBITION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PROSTAGLANDIN-F-SYNTHASE | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | MACROMOLECULAR CRYSTALLOGRAPHY | PRE-RECEPTOR REGULATION | CANCER CELL-MIGRATION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Meclofenamic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Tolmetin - analogs & derivatives | Indomethacin - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Mefenamic Acid - chemistry | Naproxen - metabolism | Sulindac - metabolism | Ibuprofen - chemistry | Mefenamic Acid - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Hydroxyprostaglandin Dehydrogenases - chemistry | Tolmetin - metabolism | Sulindac - chemistry | Flurbiprofen - chemistry | Meclofenamic Acid - chemistry | Ibuprofen - metabolism | Naproxen - chemistry | Tolmetin - chemistry | Flufenamic Acid - metabolism | Aldo-Keto Reductase Family 1 Member C3 | Flufenamic Acid - chemistry | Indomethacin - chemistry | 3-Hydroxysteroid Dehydrogenases - chemistry | Flurbiprofen - metabolism | Oxidoreductases | Research | Nonsteroidal anti-inflammatory drugs | Structure | Properties | Drugs | Dehydrogenases | Drug development | Cancer therapies | Crystallography | Cell adhesion & migration | Proteins | Signal transduction | Distributed control systems | Naproxen | Sulindac | Ibuprofen | Inhibition | Catalysis | NADP | Flurbiprofen | Crystal structure | Carbonyls | Medical research | Enzymes | Antiinflammatory agents | Breast cancer | Inflammation | Aldo-keto reductase | Carbonyl groups | Testosterone | Signaling | Acids | Mefenamic acid | Ligands | Indomethacin | Drug discovery | Prostate cancer | Prostate | Tumors | Cancer
Journal Article
Journal Article