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1. Full Text Development of potent selective competitive-antagonists of the melanocortin type 2 receptor
by Bouw, Elise and Huisman, Martin and Neggers, Sebastian J.C.M.M and Themmen, Axel P.N and van der Lely, A.J and Delhanty, Patric J.D
Molecular and cellular endocrinology, ISSN 0303-7207, 08/2014, Volume 394, Issue 1-2, pp. 99 - 104
Antagonist | Adrenocorticotropic hormone (ACTH) | Melanocortin 2 receptor (MC2R) | Cushing’s disease | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptor, Melanocortin, Type 3 - genetics | Humans | Adrenocorticotropic Hormone - pharmacology | Molecular Sequence Data | Receptor, Melanocortin, Type 3 - metabolism | Receptor, Melanocortin, Type 4 - metabolism | Structure-Activity Relationship | Receptor, Melanocortin, Type 1 - metabolism | Adrenocorticotropic Hormone - genetics | Pituitary ACTH Hypersecretion - drug therapy | Receptor, Melanocortin, Type 2 - metabolism | Dose-Response Relationship, Drug | Receptor, Melanocortin, Type 2 - genetics | Peptides - chemical synthesis | Transfection | Receptor, Melanocortin, Type 1 - chemistry | Receptors, Melanocortin - metabolism | Drug Design | HEK293 Cells | Receptor, Melanocortin, Type 2 - chemistry | Receptor, Melanocortin, Type 2 - antagonists & inhibitors | Receptor, Melanocortin, Type 3 - chemistry | Adrenocorticotropic Hormone - metabolism | Amino Acid Sequence | Gene Expression | Receptor, Melanocortin, Type 4 - chemistry | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Peptides - pharmacology | Receptors, Melanocortin - chemistry | Protein Binding | Peptides | Index Medicus
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2. Full Text Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase Receptor Type B Signaling Is a Downstream Effector of the Brainstem Melanocortin System in Food Intake Control
by Bariohay, Bruno and Roux, Julien and Tardivel, Catherine and Trouslard, Jérôme and Jean, Andre and Lebrun, Bruno
Endocrinology (Philadelphia), ISSN 0013-7227, 06/2009, Volume 150, Issue 6, pp. 2646 - 2653
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: endocrinology | Biological and medical sciences | alpha-MSH - pharmacology | Rats, Wistar | Melanocortins - metabolism | Brain Stem - metabolism | Injections, Intraventricular | Melanocyte-Stimulating Hormones - pharmacology | Receptor, Melanocortin, Type 3 - metabolism | Male | Peptides, Cyclic - pharmacology | Receptor, Melanocortin, Type 4 - metabolism | Receptor, trkB - genetics | Cholecystokinin - administration & dosage | Brain Stem - drug effects | Peptides, Cyclic - administration & dosage | Brain-Derived Neurotrophic Factor - physiology | Models, Animal | Receptor, Melanocortin, Type 3 - agonists | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | Melanocyte-Stimulating Hormones - administration & dosage | Appetite Regulation - drug effects | Cholecystokinin - pharmacology | Rats | Receptor, Melanocortin, Type 4 - agonists | Mice, Knockout | Animals | Receptor, Melanocortin, Type 3 - antagonists & inhibitors | Signal Transduction - drug effects | Signal Transduction - physiology | Mice | Appetite Regulation - physiology | alpha-MSH - analogs & derivatives | Receptor, trkB - metabolism | alpha-MSH - administration & dosage | Index Medicus | Abridged Index Medicus
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3. Full Text Biphasic Effect of Melanocortin Agonists on Metabolic Rate and Body Temperature
by Lute, Beth and Jou, William and Lateef, Dalya M and Goldgof, Margalit and Xiao, Cuiying and Piñol, Ramón A and Kravitz, Alexxai V and Miller, Nicole R and Huang, Yuning George and Girardet, Clemence and Butler, Andrew A and Gavrilova, Oksana and Reitman, Marc L
Cell metabolism, ISSN 1550-4131, 08/2014, Volume 20, Issue 2, pp. 333 - 345
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | alpha-MSH - pharmacology | Body Temperature - drug effects | Receptor, Melanocortin, Type 3 - genetics | Receptor, Melanocortin, Type 3 - metabolism | Male | Receptor, Melanocortin, Type 4 - metabolism | Receptor, Melanocortin, Type 1 - metabolism | Dopaminergic Neurons - metabolism | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | Dopaminergic Neurons - drug effects | Female | Receptor, Melanocortin, Type 3 - agonists | Arcuate Nucleus of Hypothalamus - metabolism | Mice, Inbred C57BL | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - genetics | Mice, Knockout | Animals | Dopamine Antagonists - pharmacology | Mice | alpha-MSH - analogs & derivatives | Energy Metabolism - drug effects | Receptor, Melanocortin, Type 1 - agonists | Nervous system diseases | Research institutes | Kidney diseases | Hypothermia | Index Medicus | hypotension | blood pressure | MTII | hypometabolism | hypothermia | metabolic rate | body temperature | dopamine | thermoregulation | melanocortin
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4. Full Text Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects
by Montero-Melendez, Trinidad and Gobbetti, Thomas and Cooray, Sadani N and Jonassen, Thomas E. N and Perretti, Mauro
The Journal of immunology (1950), ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3381 - 3388
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation - pathology | Arthritis, Experimental - drug therapy | Arthritis, Experimental - genetics | Calcium - metabolism | Receptor, Melanocortin, Type 3 - genetics | Humans | Receptor, Melanocortin, Type 3 - metabolism | Guanidines - pharmacology | Male | Receptor, Melanocortin, Type 1 - metabolism | Melanins - metabolism | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Peritonitis - pathology | Inflammation - metabolism | Melanoma, Experimental | Inflammation - drug therapy | Peritonitis - genetics | Pyrroles - administration & dosage | Receptors, Melanocortin - agonists | Receptors, Melanocortin - metabolism | HEK293 Cells | Anti-Inflammatory Agents - administration & dosage | Macrophages, Peritoneal - drug effects | Neutrophils - metabolism | Receptor, Melanocortin, Type 3 - agonists | Guanidines - administration & dosage | Disease Models, Animal | Anti-Inflammatory Agents - pharmacology | Peritonitis - metabolism | Receptor, Melanocortin, Type 1 - genetics | Neutrophils - immunology | Phagocytosis - immunology | Macrophages, Peritoneal - immunology | Peritonitis - chemically induced | Gene Knockout Techniques | Receptors, Melanocortin - genetics | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Inflammation - genetics | Mice | Peritonitis - drug therapy | Macrophages, Peritoneal - metabolism | Receptor, Melanocortin, Type 1 - agonists | Index Medicus | Abridged Index Medicus
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5. Full Text Further evidence on acetylation-induced inhibition of the pigment-dispersing activity of α-melanocyte-stimulating hormone
by Kobayashi, Yuki and Mizusawa, Kanta and Chiba, Hiroaki and Tagawa, Masatomo and Takahashi, Akiyoshi
General and comparative endocrinology, ISSN 0016-6480, 2011, Volume 176, Issue 1, pp. 9 - 17
Endocrinology & Metabolism | Melanocortin receptor (MCR) | α-Melanocyte-stimulating hormone (α-MSH) | Melanophores | Japanese flounder | Xanthophores | Life Sciences & Biomedicine | Science & Technology | Species Specificity | Pigments, Biological - physiology | Molecular Sequence Data | Phylogeny | Receptor, Melanocortin, Type 2 - genetics | Skin Physiological Phenomena | Receptor, Melanocortin, Type 1 - chemistry | Receptor, Melanocortin, Type 2 - chemistry | Acetylation | Pro-Opiomelanocortin - genetics | Dimerization | Amino Acid Sequence | Receptor, Melanocortin, Type 4 - chemistry | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 1 - physiology | Receptor, Melanocortin, Type 4 - genetics | Receptors, Melanocortin - physiology | Receptors, Melanocortin - genetics | Receptors, Melanocortin - chemistry | Animals | Flounder - physiology | alpha-MSH - physiology | Receptor, Melanocortin, Type 2 - physiology | Melanophores - physiology | Receptor, Melanocortin, Type 4 - physiology | Index Medicus
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6. Melanocortins
: multiple actions and therapeutic potential
by Catania, Anna
2010, Advances in experimental medicine and biology, ISBN 9781441963536, Volume 681., xx, 153
physiology | Melanocortins | metabolism | Receptors, Melanocortin | therapeutic use | MSH (Hormone)
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7. Full Text Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake
by Heisler, Lora K and Jobst, Erin E and Sutton, Gregory M and Zhou, Ligang and Borok, Erzsebet and Thornton-Jones, Zoe and Liu, Hong Yan and Zigman, Jeffrey M and Balthasar, Nina and Kishi, Toshiro and Lee, Charlotte E and Aschkenasi, Carl J and Zhang, Chen-Yu and Yu, Jia and Boss, Olivier and Mountjoy, Kathleen G and Clifton, Peter G and Lowell, Bradford B and Friedman, Jeffrey M and Horvath, Tamas and Butler, Andrew A and Elmquist, Joel K and Cowley, Michael A
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2006, Volume 51, Issue 2, pp. 239 - 249
HUMDISEASE | MOLNEURO | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Serotonin 5-HT1 Receptor Agonists | Serotonin - physiology | Electric Stimulation | Mice, Inbred A | Male | Nerve Net - drug effects | Serotonin - pharmacology | Nerve Net - physiology | Eating - physiology | Receptors, Melanocortin - agonists | Neurons - physiology | Neurons - drug effects | Receptor, Melanocortin, Type 4 - antagonists & inhibitors | Receptors, Melanocortin - antagonists & inhibitors | Mice, Inbred C57BL | Mice, Transgenic | Receptor, Melanocortin, Type 4 - agonists | Receptor, Serotonin, 5-HT1B - physiology | Receptors, Melanocortin - physiology | Mice, Knockout | Eating - drug effects | Animals | Mice, Obese | Mice | Pyridines - pharmacology | Receptor, Melanocortin, Type 3 - physiology | Receptor, Melanocortin, Type 4 - physiology | Medical colleges | Molecular genetics | Serotonin | Neurons | Physiological aspects | Phenols | Diabetes | Peptide hormones | Obesity | Nutrition research | Brain research | Rodents | Monitoring systems | Homeostasis | Variance analysis | Drug dosages | Food | Index Medicus
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8. Full Text Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response
by Malik, Ihtzaz Ahmed and Malik, Ihtzaz Ahmed and Triebel, Jakob and Triebel, Jakob and Posselt, Jessica and Posselt, Jessica and Khan, Sajjad and Khan, Sajjad and Ramadori, Pierluigi and Ramadori, Pierluigi and Raddatz, Dirk and Raddatz, Dirk and Ramadori, Giuliano and Ramadori, Giuliano
Histochemistry and cell biology, ISSN 0948-6143, 3/2012, Volume 137, Issue 3, pp. 279 - 291
Brain | Medicine & Public Health | Cytokines | Acute-phase response | Liver | Melanocortin receptors | Anatomy | Medicine/Public Health, general | Life Sciences & Biomedicine | Microscopy | Technology | Science & Technology | Cell Biology | alpha-MSH - pharmacology | Gene Expression - drug effects | Rats, Wistar | Acute-Phase Reaction - immunology | Receptor, Melanocortin, Type 3 - genetics | Humans | Male | Brain - physiology | Receptor, Melanocortin, Type 2 - genetics | Liver - immunology | alpha-MSH - blood | Leptin - blood | Gene Expression - immunology | Hepatocytes - drug effects | Tetrahydroisoquinolines - pharmacology | Interleukin-6 - genetics | Mice, Inbred C57BL | Receptor, Melanocortin, Type 1 - genetics | Rats | Receptor, Melanocortin, Type 4 - genetics | Hepatocytes - immunology | Receptor, Melanocortin, Type 3 - immunology | Receptor, Melanocortin, Type 4 - immunology | Receptors, Melanocortin - genetics | Hep G2 Cells | Kupffer Cells - drug effects | Mice, Knockout | Triazoles - pharmacology | Animals | Receptor, Melanocortin, Type 2 - immunology | Receptor, Melanocortin, Type 1 - immunology | Liver - cytology | Mice | Receptors, Melanocortin - immunology | Kupffer Cells - immunology | Anopheles | Liver diseases | RNA | Genes | Leptin | Intermedin | Universities and colleges | Gene expression | Cells | Hormones | Index Medicus | Original Paper
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9. Full Text γ2-Melanocyte stimulation hormone (γ2- MSH) truncation studies results in the cautionary note that γ2- MSH is not selective for the mouse MC3R over the mouse MC5R
by Joseph, Christine G and Yao, Hua and Scott, Joseph W and Sorensen, Nicholas B and Marnane, Rebecca N and Mountjoy, Kathleen G and Haskell-Luevano, Carrie
Peptides (New York, N.Y. : 1980), ISSN 0196-9781, 12/2010, Volume 31, Issue 12, pp. 2304 - 2313
Heart | Obesity | GPCR | Receptor brain expression | Blood pressure | Melanotropin | alpha-MSH - pharmacology | Receptor, Melanocortin, Type 3 - genetics | gamma-MSH - pharmacology | Humans | Receptor, Melanocortin, Type 3 - metabolism | Male | Receptor, Melanocortin, Type 4 - metabolism | Structure-Activity Relationship | Receptor, Melanocortin, Type 1 - metabolism | Brain - metabolism | Receptor, Melanocortin, Type 1 - chemistry | Receptors, Melanocortin - metabolism | Cyclic AMP - metabolism | Receptor, Melanocortin, Type 3 - chemistry | Cell Line | Receptor, Melanocortin, Type 4 - chemistry | Receptor, Melanocortin, Type 1 - genetics | Receptor, Melanocortin, Type 4 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Melanocortin - genetics | Brain - drug effects | Receptors, Melanocortin - chemistry | Animals | Mice | alpha-MSH - analogs & derivatives | Index Medicus
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10. Full Text Studies on the Physiological Functions of the Melanocortin System
by Cone, Roger D
Endocrine reviews, ISSN 0163-769X, 12/2006, Volume 27, Issue 7, pp. 736 - 749
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Receptors, Corticotropin - physiology | Cachexia - genetics | Agouti Signaling Protein | Receptor, Melanocortin, Type 3 - genetics | Humans | Intercellular Signaling Peptides and Proteins - genetics | Signal Transduction - genetics | Receptors, Melanocortin - physiology | Receptors, Melanocortin - genetics | Intercellular Signaling Peptides and Proteins - physiology | Melanocortins - physiology | Animals | Melanocortins - genetics | Alleles | Signal Transduction - physiology | Receptor, Melanocortin, Type 3 - physiology | Receptors, Corticotropin - genetics | Agouti-Related Protein | Cachexia - physiopathology | Index Medicus
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