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Journal of cellular and molecular medicine, ISSN 1582-1838, 05/2017, Volume 21, Issue 5, pp. 968 - 974
Journal Article
General and Comparative Endocrinology, ISSN 0016-6480, 2011, Volume 176, Issue 1, pp. 9 - 17
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 10/2017, Volume 1863, Issue 10, pp. 2436 - 2447
Journal Article
Data in Brief, ISSN 2352-3409, 06/2016, Volume 7, Issue C, pp. 1670 - 1677
This article contains structure and pharmacological characteristics of melanocortin receptors (MCRs) related to research published in “Characterization of... 
Melanocortin receptor (MCR) | Melanocyte-stimulating hormone (MSH) | Adrenocorticotropic hormone (ACTH) | Dasyatis akajei | Stingray
Journal Article
Current Protein and Peptide Science, ISSN 1389-2037, 08/2016, Volume 17, Issue 5, pp. 488 - 496
The melanocortin receptor system consists of five closely related G-protein coupled receptors (MC1R, MC2R, MC3R, MC4R and MC5R). These receptors are involved... 
GPCRs: G-protein coupled receptors | Lys | AGRP: agouti related protein | ) | Ac-Nle-c[Asp-His- D-Nal(2’)-Arg-Trp-Lys]-NH | Α-MSH: α -melanocyte stimulate hormone | ACTH: adrenal corticotropic hormone | SHU9119: Ac- Nle | α-MSH(4-10)-NH | MTI: Ac-Ser-Tyr-Ser-Met-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val- NH | Melanocortin Receptors (MCRs: MC1R, MC2R, MC3R, MC4R, MC5R) | MT-II: Ac-Nle | D-Phe | POMC: Proopiomelanocortin | ASIP: agouti signaling protein | c[Asp | D-Nal(2’) | Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH | alpha-MSH: alpha-melanocyte stimulate hormone | SHU9119: Ac-Nle-c[Asp, D-Nal(2 '), Lys]alpha-MSH(4-10)-NH2, (Ac-Nle-c[Asp-His-D-Nal(2 ')-Arg-Trp-Lys]-NH2) | ALPHA-MELANOTROPIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PENILE ERECTION | DRUG DISCOVERY | MTI: Ac-Ser-Tyr-Ser-Met-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val-NH2 | AGOUTI SIGNALING PROTEIN | OBESITY SYNDROME | MELANOCYTE-STIMULATING HORMONE | DESIGNING PEPTIDE | MT-II: Ac-Nle-c[Asp, D-Phe, Lys]alpha-MSH(4-10)-NH2, (Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2) | MOLECULAR-CLONING | HIGHLY POTENT | ERECTILE DYSFUNCTION | Peptides - chemistry | Melanocortins - chemistry | Melanocortins - metabolism | Humans | Melanocyte-Stimulating Hormones - metabolism | Models, Molecular | Structure-Activity Relationship | Receptors, Melanocortin - genetics | Molecular Mimicry | Receptors, Melanocortin - chemistry | Animals | Peptides - metabolism | Melanocortins - genetics | Melanocyte-Stimulating Hormones - chemistry | Receptors, Melanocortin - metabolism | Drug Design | Ligands | Protein Conformation | Molecular Structure
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 08/2010, Volume 401, Issue 3, pp. 433 - 450
Melanocortin-4 receptor (MC4R) has an important regulatory role in energy homeostasis and food intake. Peptide agonists of the MC4R are characterized by the... 
melanocortin-4 receptor (MC4R) | [Nle4,d-Phe7]melanocyte-stimulating hormone (NDP-MSH) | comparative model | G-protein-coupled receptor (GPCR) | cysteine cross-linking | d-Phe | melanocyte-stimulating hormone (NDP-MSH) | Nle | Comparative model | Cysteine cross-linking | Melanocortin-4 receptor (MC4R) | LIGAND-BINDING | ALPHA-MELANOTROPIN | [Nle,D-Phe]melanocyte-stimulating hormone (NDP-MSH) | CONSTITUTIVE ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSMEMBRANE DOMAIN | MOLECULAR DETERMINANTS | TETRAPEPTIDE AC-HIS-DPHE-ARG-TRP-NH2 | 3-DIMENSIONAL STRUCTURE | MINIMAL ACTIVE SEQUENCE | AGOUTI-RELATED PROTEIN | SECONDARY STRUCTURE | Catalytic Domain | Peptides | Humans | Crystallography, X-Ray | Receptor, Melanocortin, Type 4 - metabolism | Receptor, Melanocortin, Type 4 - agonists | Receptor, Melanocortin, Type 4 - genetics | Static Electricity | alpha-MSH - metabolism | Ligands | Protein Conformation | Mutation | alpha-MSH - analogs & derivatives | Rhodopsin | Cysteine | Intermedin | Analysis | Cystine | PDB, Protein Data Bank | TM, transmembrane | WT, wild type | CuP, copper 1,10-phenanthroline | MC1R, melanocortin-1 receptor | NDP-MSH, [Nle4,d-Phe7]melanocyte-stimulating hormone | ECL, extracellular loop | hMC4R, human MC4R | PDF, probability density function | GPCR, G-protein-coupled receptor | MSH, melanocyte-stimulating hormone | CRE, cyclic AMP response element | MTII, melanotan II | MC4R, melanocortin-4 receptor | MCR, melanocortin receptor | d-Nal, β-(2-naphthyl)-d-alanine
Journal Article
Journal Article