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Science, ISSN 0036-8075, 06/2016, Volume 352, Issue 6292, pp. 1436 - 1443
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 05/2003, Volume 22, Issue 20, pp. 3138 - 3151
Melanoma is the most aggressive form of skin cancer and is notoriously resistant to all current modalities of cancer therapy. A large set of genetic,... 
Drug resistance | Cancer therapy | Chemotherapeutic targets | Apoptosis | Skin cancer | WILD-TYPE P53 | skin cancer | PROTEIN-KINASE-B | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | MALIGNANT-MELANOMA | DIFFERENTIATION-ASSOCIATED GENE-7 | CELL BIOLOGY | PROGRAMMED CELL-DEATH | cancer therapy | HUMAN METASTATIC MELANOMA | ONCOLOGY | chemotherapeutic targets | SMALL-MOLECULE INHIBITORS | IN-VIVO | GENETICS & HEREDITY | drug resistance | CYTOCHROME-C RELEASE | NF-KAPPA-B | Caspase 9 | Skin Neoplasms - drug therapy | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Humans | NF-kappa B - metabolism | Microtubule-Associated Proteins - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | PTEN Phosphohydrolase | Melanocytes - drug effects | Neoplasm Proteins | Caspases - drug effects | Antineoplastic Agents - pharmacology | Cell Survival - physiology | Skin Neoplasms - pathology | Apoptotic Protease-Activating Factor 1 | Cell Survival - drug effects | Tumor Suppressor Proteins - metabolism | Inhibitor of Apoptosis Proteins | Signal Transduction | Mitochondria - metabolism | Melanoma - pathology | Mitochondria - drug effects | Disease Progression | Animals | Proteins - metabolism | Melanoma - drug therapy | Proto-Oncogene Proteins c-bcl-2 - drug effects | Proteins - drug effects | Apoptosis - physiology | Phosphoric Monoester Hydrolases - metabolism | Tumor Suppressor Protein p14ARF - metabolism | Drug Resistance, Neoplasm - physiology | NF-kappa B - drug effects | Tumor Suppressor Protein p14ARF - drug effects
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2010, Volume 30, Issue 35, pp. 11815 - 11825
Journal Article
Cancer Discovery, ISSN 2159-8274, 2014, Volume 4, Issue 7, pp. 816 - 827
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e58721 - e58721
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 03/2014, Volume 18, Issue 3, pp. 514 - 529
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 03/2013, Volume 26, Issue 2, pp. 205 - 217
Summary We present here the positional cloning of the Danio rerio albino mutant and show that the affected gene encodes Slc45a2. The human orthologous gene has... 
V‐ATPase | melanosome | melanocyte | retinal pigment epithelium | skin color variation | albinism | slc45a2 | V-ATPase | PROTEIN | OCULOCUTANEOUS ALBINISM | ORGANELLES | TYROSINASE | IDENTIFICATION | CELL BIOLOGY | DERMATOLOGY | MUTANTS | POLYMORPHISMS | GENE | ONCOLOGY | MUTATIONS | EXCHANGER | Organ Specificity - drug effects | Retina - drug effects | Melanophores - metabolism | Melanosomes - ultrastructure | Retina - metabolism | Humans | Neural Crest - pathology | Molecular Sequence Data | Melanocytes - metabolism | Vacuolar Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Monophenol Monooxygenase - metabolism | Neural Crest - metabolism | Visual Acuity - drug effects | Hydrogen-Ion Concentration - drug effects | Melanocytes - pathology | Cloning, Molecular | Membrane Transport Proteins - metabolism | Homeostasis - drug effects | Melanosomes - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Pigmentation - drug effects | Zebrafish Proteins - chemistry | Zebrafish Proteins - metabolism | Mutation - genetics | Membrane Transport Proteins - chemistry | Neural Crest - drug effects | Biological Evolution | Vacuolar Proton-Translocating ATPases - antagonists & inhibitors | Animals | Models, Biological | Zebrafish - metabolism | Alleles | Morpholinos - pharmacology | Melanophores - drug effects | Protein Subunits - chemistry | Melanosomes - metabolism | Retina - pathology | Skin color variation | Slc45a2 | Albinism | Melanocyte | Melanosome | Retinal pigment epithelium | Proteins | Skin | Hydrogen-ion concentration | Analysis | Adenosine triphosphatase | Zebrafish
Journal Article