X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (31798) 31798
Book Review (3141) 3141
Publication (2778) 2778
Newsletter (2274) 2274
Newspaper Article (1042) 1042
Conference Proceeding (168) 168
Book Chapter (165) 165
Magazine Article (34) 34
Book / eBook (27) 27
Trade Publication Article (26) 26
Transcript (26) 26
Dissertation (22) 22
Web Resource (9) 9
Reference (3) 3
Data Set (2) 2
Journal / eJournal (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (26152) 26152
humans (19950) 19950
melanoma (18794) 18794
animals (12986) 12986
mice (9506) 9506
cancer (9024) 9024
biochemistry & molecular biology (8806) 8806
cell line, tumor (6887) 6887
oncology (6455) 6455
female (6151) 6151
cell biology (6023) 6023
male (4982) 4982
melanoma - pathology (4795) 4795
apoptosis (4417) 4417
research (4102) 4102
expression (4008) 4008
metastasis (3944) 3944
tumors (3924) 3924
biochemistry (3770) 3770
melanoma - metabolism (3358) 3358
tumor cells, cultured (3354) 3354
proteins (3084) 3084
analysis (2938) 2938
middle aged (2602) 2602
cells (2588) 2588
melanoma - genetics (2572) 2572
pharmacology & pharmacy (2562) 2562
mice, inbred c57bl (2528) 2528
dermatology (2441) 2441
care and treatment (2401) 2401
gene expression (2399) 2399
malignant-melanoma (2349) 2349
article (2292) 2292
immunotherapy (2237) 2237
melanoma - drug therapy (2224) 2224
adult (2221) 2221
antineoplastic agents - pharmacology (2203) 2203
melanoma-cells (2110) 2110
skin cancer (2093) 2093
aged (2082) 2082
skin neoplasms - pathology (2038) 2038
medicine (1935) 1935
chemistry, medicinal (1909) 1909
immunology (1880) 1880
cell line (1878) 1878
molecular sequence data (1878) 1878
molecular biology (1854) 1854
immunohistochemistry (1837) 1837
mutation (1837) 1837
signal transduction (1836) 1836
in-vitro (1827) 1827
research article (1792) 1792
biophysics (1789) 1789
genetic aspects (1780) 1780
activation (1779) 1779
medicine, research & experimental (1736) 1736
health aspects (1730) 1730
growth (1684) 1684
melanoma, experimental - pathology (1667) 1667
multidisciplinary sciences (1642) 1642
in-vivo (1635) 1635
genetics & heredity (1618) 1618
skin (1582) 1582
apoptosis - drug effects (1566) 1566
metastatic melanoma (1554) 1554
cell proliferation - drug effects (1543) 1543
inhibition (1518) 1518
amino acid sequence (1511) 1511
biology (1509) 1509
cell proliferation (1504) 1504
cytotoxicity (1492) 1492
chemotherapy (1467) 1467
chemistry, multidisciplinary (1458) 1458
gene expression regulation, neoplastic (1429) 1429
cells, cultured (1346) 1346
kinases (1321) 1321
cell survival - drug effects (1311) 1311
therapy (1292) 1292
breast-cancer (1289) 1289
physiological aspects (1279) 1279
science (1271) 1271
phosphorylation (1270) 1270
melanoma - immunology (1267) 1267
pathology (1253) 1253
angiogenesis (1242) 1242
medical research (1228) 1228
cancer therapies (1210) 1210
dose-response relationship, drug (1183) 1183
neoplasm metastasis (1179) 1179
genes (1160) 1160
development and progression (1157) 1157
melanoma, experimental - drug therapy (1157) 1157
metastases (1153) 1153
transfection (1140) 1140
antigens (1139) 1139
mice, nude (1139) 1139
identification (1115) 1115
melanoma, experimental - metabolism (1103) 1103
flow cytometry (1101) 1101
base sequence (1097) 1097
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (26) 26
Collection Dvlpm't (Acquisitions) - Closed Orders (3) 3
Scarborough Hospital - General (2) 2
Humber River Regional Hospital - Finch Stacks (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Providence Healthcare - Stacks (1) 1
Scarborough Hospital - Birchmount (1) 1
St Josephs Health Centre - Stacks (1) 1
St. Michael's Hospital - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (35118) 35118
French (56) 56
Chinese (50) 50
Japanese (50) 50
German (43) 43
Russian (29) 29
Spanish (15) 15
Italian (11) 11
Czech (9) 9
Korean (5) 5
Polish (5) 5
Hungarian (4) 4
Portuguese (4) 4
Turkish (2) 2
Slovak (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 1, pp. 356 - 366
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 198, pp. 91 - 103
We hypothesized that the co-entrapment of melanoma-associated antigens and the Toll-like receptor (TLR) ligands Poly(I:C) and CpG, known to be... 
Nanoparticles | Cancer vaccine | PLGA | Melanoma | Antigen presenting cells | Mannose receptor targeting | TLR | DENDRITIC CELLS | VACCINE DELIVERY | BIODEGRADABLE NANOPARTICLES | MICROSPHERE | CHEMISTRY, MULTIDISCIPLINARY | PLGA-BASED NANOPARTICLES | S. EQUI ANTIGENS | IMMUNOTHERAPY | PHARMACOLOGY & PHARMACY | EXPRESSION | T-LYMPHOCYTES | OVALBUMIN | Oligodeoxyribonucleotides - administration & dosage | gp100 Melanoma Antigen - chemistry | Immunoglobulin G - blood | Nanoparticles - chemistry | Ovalbumin - immunology | Poly I-C - administration & dosage | Granzymes - metabolism | Oligodeoxyribonucleotides - chemistry | Male | gp100 Melanoma Antigen - immunology | Peptides - administration & dosage | MART-1 Antigen - administration & dosage | Cancer Vaccines | Female | Ovalbumin - chemistry | Cytokines - immunology | Disease Models, Animal | Mannose - chemistry | MART-1 Antigen - chemistry | MART-1 Antigen - immunology | Peptides - chemistry | gp100 Melanoma Antigen - administration & dosage | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Mice, Transgenic | Melanoma - pathology | Poly I-C - chemistry | Animals | Ovalbumin - administration & dosage | Tumor Burden - drug effects | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Polymers - chemistry | Nanoparticles - administration & dosage | Immune response | Peptides | Analysis | Immunotherapy | Health aspects | Sugars | Tumors | Monosaccharides | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 04/2013, Volume 167, Issue 1, pp. 40 - 52
Combination therapies for cancer aim to exploit either additive or synergistic effects arising from the action of two species with the final goal to maximize... 
Nanoparticles | Poly(epsiloncaprolactone) | Photodynamic therapy | Poly(ethyleneoxide) | Amphiphilic block copolymers | Docetaxel | PHOTOSENSITIZERS | MICELLES | FORMULATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | VEHICLES | PHARMACOLOGY & PHARMACY | WHOLE-BODY | Hemolysis - drug effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Photosensitizing Agents - chemistry | Skin Neoplasms - drug therapy | Nanoparticles - chemistry | Antineoplastic Combined Chemotherapy Protocols - chemistry | Apoptosis - drug effects | Humans | Drug Carriers - administration & dosage | Antineoplastic Agents - administration & dosage | Photochemotherapy | Drug Carriers - chemistry | Indoles - administration & dosage | Photosensitizing Agents - administration & dosage | Female | Skin Neoplasms - pathology | Taxoids - chemistry | Cell Survival - drug effects | Drug Stability | Antineoplastic Agents - chemistry | Melanoma, Amelanotic - drug therapy | Melanoma, Amelanotic - pathology | Taxoids - administration & dosage | Animals | Singlet Oxygen - chemistry | Tumor Burden - drug effects | Mice, Nude | Plasma - chemistry | Cell Line, Tumor | Organometallic Compounds - chemistry | Mice | Nanoparticles - administration & dosage | Indoles - chemistry | Organometallic Compounds - administration & dosage | Antimitotic agents | Oligomers | Care and treatment | Chemotherapy | Analysis | Phthalocyanins | Fluorescence | Ethylene oxide | Antineoplastic agents | Health aspects | Block copolymers | Cancer | Index Medicus
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 02/2017, Volume 95, pp. 1072 - 1081
Lectins are proteins able to interact specifically and reversibly with carbohydrates. They are present in all living beings, particularly in legume seeds,... 
Antitumour | Lectin | Gastroprotective | Purification | Phaseolus | Antioxidant | CELLS | ANTIPROLIFERATIVE ACTIVITY | POLYMER SCIENCE | HEMOLYTIC-ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING LECTIN | VULGARIS L | CONCANAVALIN-A | HEMAGGLUTININS | PLANT-LECTINS | CHEMISTRY, APPLIED | PROTEINS | Molecular Weight | Antioxidants - chemistry | Humans | Plant Lectins - isolation & purification | Stomach Ulcer - pathology | Male | Gastrointestinal Agents - chemistry | Urea - chemistry | Sulfonic Acids - chemistry | Biphenyl Compounds - antagonists & inhibitors | Gastrointestinal Agents - isolation & purification | Picrates - chemistry | Protein Denaturation | Benzothiazoles - antagonists & inhibitors | Plant Lectins - chemistry | Seeds - chemistry | Biphenyl Compounds - chemistry | Stomach - drug effects | Stomach Ulcer - chemically induced | Hemagglutination Tests | Stomach - pathology | Ethanol | Stomach Ulcer - drug therapy | Antineoplastic Agents, Phytogenic - chemistry | Plant Lectins - pharmacology | Antioxidants - pharmacology | Acetylgalactosamine - chemistry | Phaseolus - chemistry | Sulfonic Acids - antagonists & inhibitors | Erythrocytes - drug effects | Gastrointestinal Agents - pharmacology | Picrates - antagonists & inhibitors | Animals | Antioxidants - isolation & purification | Solid Phase Extraction - methods | Benzothiazoles - chemistry | Cell Line, Tumor | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Dextran | Antioxidants | Legumes | Urea | Beans | Seeds | Melanoma | Lectins | Molecular biology | Mimosaceae | Chromatography | Organic acids | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2010, Volume 18, Issue 15, pp. 5738 - 5748
Here, we present a structural comparison of the important and similar interactions necessary for Gleevec®, Nexavar®, and BIRB-796 to bind to their respective... 
Allosteric structure based drug design kinase type II | CHEMISTRY, MEDICINAL | PROTEIN | C-ABL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | SORAFENIB | CANCER | P38 MAP KINASE | HEPATOCELLULAR-CARCINOMA | MELANOMA | BRAF MUTATIONS | IMATINIB | B-RAF | Niacinamide - analogs & derivatives | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Proto-Oncogene Proteins c-abl - antagonists & inhibitors | Pyridines - chemistry | Allosteric Regulation | Antineoplastic Agents - chemical synthesis | Crystallography, X-Ray | Phenylurea Compounds | Piperazines - chemistry | Pyrimidines - chemistry | Benzenesulfonates - pharmacology | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Mitogen-Activated Protein Kinase 14 - metabolism | Computer Simulation | Drug Design | Antineoplastic Agents - pharmacology | Oligopeptides - chemistry | Proto-Oncogene Proteins B-raf - metabolism | Pyrazoles - pharmacology | Naphthalenes - chemistry | Amino Acid Sequence | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Imatinib Mesylate | Piperazines - pharmacology | Naphthalenes - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Benzenesulfonates - chemistry | Hydrogen Bonding | Proto-Oncogene Proteins c-abl - metabolism | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Benzamides | Adenosine Triphosphate - chemistry | Antimitotic agents | Chemical properties | Antineoplastic agents | Pharmacy | Analysis | Index Medicus
Journal Article
Coordination Chemistry Reviews, ISSN 0010-8545, 2009, Volume 253, Issue 11, pp. 1670 - 1681
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2014, Volume 15, Issue 10, pp. 17565 - 17576
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 11/2017, Volume 28, Issue 11, pp. 2756 - 2771
Personalized cancer vaccines (PCVs) are receiving attention as an avenue for cancer immunotherapy. PCVs employ immunogenic peptide epitopes capable of... 
T-CELL RESPONSE | DENDRITIC CELLS | BRANCHED POLYPEPTIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | EPITOPE PEPTIDES | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | NANOPARTICLE VACCINES | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY-SYSTEM | ADVANCED MELANOMA | HSV-1 GLYCOPROTEIN-D | IMMUNE-RESPONSES | Nanoparticles - chemistry | Melanoma, Experimental - drug therapy | Membrane Proteins - therapeutic use | Cancer Vaccines - chemistry | Azides - chemistry | Cancer Vaccines - therapeutic use | Melanoma, Experimental - immunology | Nanoparticles - therapeutic use | Immunotherapy | Peptide Fragments - immunology | Female | Precision Medicine | Peptides - chemistry | Click Chemistry | Mice, Inbred C57BL | Peptides - immunology | Membrane Proteins - immunology | Alkynes - chemistry | Cancer Vaccines - immunology | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Cell Line, Tumor | Mice | Peptide Fragments - therapeutic use | Peptides - therapeutic use | Self assembly | Flow cytometry | Peptides | Toxicity | Immune clearance | Amino acids | Photon correlation spectroscopy | Vaccines | Hydrophobicity | Nanoparticles | Cancer vaccines | Biocompatibility | Chemical synthesis | Alkynes | Immune system | CpG islands | Antigens | Dendritic cells | Light scattering | Melanoma | Epitopes | Electron microscopy | Cytometry | Self-assembly | Transmission electron microscopy | Immunogenicity | Antigen-presenting cells | In vivo methods and tests | Conjugation | Cancer | Tumors | Index Medicus
Journal Article