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Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7299, pp. 813 - 817
Down's syndrome (DS) is a genetic disorder caused by full or partial trisomy of human chromosome 21 and presents with many clinical phenotypes including a reduced incidence of solid tumours... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Transcriptional Regulator ERG | Neoplasm Transplantation | Oncogene Proteins - genetics | Cell Adhesion Molecules - genetics | Chromosomes, Mammalian - genetics | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Male | Down Syndrome - physiopathology | Vascular Endothelial Growth Factor A - metabolism | Immunoglobulins - genetics | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Carcinoma, Lewis Lung - blood supply | Neovascularization, Pathologic - pathology | Immunoglobulins - metabolism | Carcinoma, Lewis Lung - complications | Proto-Oncogene Protein c-ets-2 - genetics | Down Syndrome - complications | Female | Proto-Oncogene Protein c-ets-2 - metabolism | Vascular Endothelial Growth Factor A - pharmacology | ADAMTS1 Protein | Disease Models, Animal | Gene Dosage - genetics | Melanoma, Experimental - blood supply | Oncogene Proteins - metabolism | Melanoma, Experimental - complications | Melanoma, Experimental - pathology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Cell Adhesion Molecules - metabolism | Carrier Proteins - genetics | ADAM Proteins - metabolism | Animals | Carcinoma, Lewis Lung - genetics | Carrier Proteins - metabolism | Melanoma, Experimental - genetics | Trisomy - genetics | Down Syndrome - genetics | Carcinoma, Lewis Lung - pathology | Neovascularization, Pathologic - genetics | Mice | Transcription Factors | ADAM Proteins - genetics | Complications and side effects | Physiological aspects | Development and progression | Genetic aspects | Down syndrome | Neovascularization | Research | Risk factors | Tumors | Proteins | Studies | Angiogenesis | Genotype & phenotype | Rodents | Blood vessels | Genetic engineering | Gene therapy | Vascular endothelial growth factor | Index Medicus
Journal Article
by Fu, X and Meng, Z and Liang, W and Tian, Y and Wang, X and Han, W and Lou, G and Lou, F and Yen, Y and Yu, H and Jove, R and Huang, W
Oncogene, ISSN 1476-5594, 09/2013, Volume 33, Issue 34, pp. 4296 - 4306
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2015, Volume 125, Issue 2, pp. 621 - 635
The gene encoding F-box protein FBXW7 is frequently mutated in many human cancers. Although most previous studies have focused on the tumor-suppressive... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | F-Box-WD Repeat-Containing Protein 7 | Receptors, Notch - metabolism | Stromal Cells - pathology | Humans | Gene Expression Regulation, Neoplastic | Receptors, Notch - genetics | CD2 Antigens - genetics | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Breast Neoplasms - therapy | Neoplasm Metastasis | Mammary Neoplasms, Experimental - pathology | Cell Cycle Proteins - genetics | Female | CD2 Antigens - metabolism | Chemokine CCL2 - metabolism | Retrospective Studies | Neoplasm Proteins - genetics | Macrophages - pathology | Neoplasm Proteins - biosynthesis | Stromal Cells - metabolism | F-Box Proteins - biosynthesis | Chemokine CCL2 - genetics | Mice, Transgenic | Cell Cycle Proteins - biosynthesis | Ubiquitin-Protein Ligases - biosynthesis | Mammary Neoplasms, Experimental - therapy | Macrophages - metabolism | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Development and progression | Genetic aspects | Metastasis | Carrier proteins | Health aspects | Cellular control mechanisms | Proteins | Statistical analysis | Genes | Rodents | Melanoma | Breast cancer | Tumorigenesis | Mutation | Chemokines | Tumors | Recruitment | Index Medicus | Abridged Index Medicus
Journal Article
Clinical cancer research, ISSN 1557-3265, 06/2018, Volume 24, Issue 11, pp. 2574 - 2584
Journal Article
Molecular therapy, ISSN 1525-0016, 10/2014, Volume 22, Issue 10, pp. 1851 - 1863
Optimum clinical protocols require systemic delivery of oncolytic viruses in the presence of an intact immune system. We show that preconditioning with immune... 
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mammalian orthoreovirus 3 - immunology | Genetic Vectors - administration & dosage | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Receptors, Fc - metabolism | Antibodies, Neutralizing - metabolism | Melanoma, Experimental - metabolism | Monocytes - metabolism | Monocytes - immunology | Immunity - drug effects | Antibodies, Neutralizing - immunology | Melanoma, Experimental - immunology | Killer Cells, Natural - immunology | Female | Cytotoxicity, Immunologic - drug effects | Macrophages - immunology | Gene Transfer Techniques | Transduction, Genetic | Cytokines - metabolism | Genetic Vectors - immunology | Melanoma, Experimental - mortality | Melanoma, Experimental - therapy | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Melanoma, Experimental - pathology | Oncolytic Viruses - genetics | Tumor Burden | Antibodies, Viral | Genetic Vectors - genetics | Oncolytic Virotherapy | Gene Expression Regulation - drug effects | Monocytes - drug effects | Macrophages - metabolism | Animals | Melanoma, Experimental - genetics | Mammalian orthoreovirus 3 - genetics | Oncolytic Viruses - immunology | Macrophages - drug effects | Receptors, Fc - genetics | Killer Cells, Natural - drug effects | Mice | CD11b Antigen - metabolism | Killer Cells, Natural - metabolism | Cytokines - pharmacology | Index Medicus | Original
Journal Article
Journal Article
PLoS genetics, ISSN 1553-7404, 06/2013, Volume 9, Issue 6, pp. e1003531 - e1003531
Journal Article
PloS one, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, pp. e0162064 - e0162064
Journal Article
Journal Article