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1. Full Text Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells
by Zhao, Wen‐Jie and Zhang, Min and Miao, Yanying and Yang, Xiong‐Li and Wang, Zhongfeng
The Journal of Physiology, ISSN 0022-3751, 07/2010, Volume 588, Issue 14, pp. 2605 - 2619
In vertebrate retina, melatonin regulates various physiological functions. In this work we investigated the mechanisms underlying melatonin‐induced... 
CIRCADIAN CLOCK | XENOPUS-LAEVIS | BIPOLAR CELLS | PROTEIN-KINASE-C | PHYSIOLOGY | FISH RETINA | PHOSPHOLIPASE-C | VISUAL PATHWAY | FUNCTIONAL-ROLE | MT2 MELATONIN | RECEPTORS | NEUROSCIENCES | Cyclic GMP - pharmacology | Receptor, Melatonin, MT2 - antagonists & inhibitors | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Male | Calcium - analysis | Melatonin - physiology | Type C Phospholipases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - physiology | Isoquinolines - pharmacology | Cyclic GMP - analogs & derivatives | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Bridged-Ring Compounds - pharmacology | Egtazic Acid - analogs & derivatives | Indoles - pharmacology | Guanosine Diphosphate - pharmacology | Pertussis Toxin - pharmacology | Retinal Ganglion Cells - physiology | Protein Kinase C - physiology | Retinal Ganglion Cells - enzymology | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Receptor, Melatonin, MT2 - physiology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Animals | Egtazic Acid - pharmacology | Glycine - physiology | Guanosine Diphosphate - analogs & derivatives | Signal Transduction - drug effects | Tetrahydronaphthalenes - pharmacology | Thiones - pharmacology | Carbazoles - pharmacology | Type C Phospholipases - physiology | Melatonin | Phospholipids | Glycine | Ganglion | Gross domestic product | Protein kinases | Kinases | Retina | Physiology | Neuroscience
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2. Full Text International union of basic and clinical pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors
by Dubocovich, Margarita L and Delagrange, Philippe and Krause, Diana N and Sugden, David and Cardinali, Daniel P and Olcese, James
Pharmacological Reviews, ISSN 0031-6997, 09/2010, Volume 62, Issue 3, pp. 343 - 380
The hormone melatonin (5-methoxy-N-acetyltryptamine) is synthesized primarily in the pineal gland and retina, and in several peripheral tissues and organs. In... 
XENOPUS DERMAL MELANOPHORES | CONFORMATIONALLY RESTRICTED LIGANDS | MESSENGER-RNA EXPRESSION | RAT SUPRACHIASMATIC NUCLEUS | SEROTONIN N-ACETYLTRANSFERASE | PANCREATIC BETA-CELLS | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | HUMAN BREAST-CANCER | SITE-DIRECTED MUTAGENESIS | VASCULAR SMOOTH-MUSCLE | Terminology as Topic | Receptors, Melatonin - classification | Animals | Receptors, Melatonin - chemistry | Receptors, Melatonin - metabolism | Humans | Index Medicus | IUPHAR Nomenclature Reports
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3. Full Text Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats
by Tota, Santoshkumar and Goel, Ruby and Pachauri, Shakti Deep and N, Rajasekar and Najmi, Abul Kalam and Hanif, Kashif and Nath, Chandishwar
Psychopharmacology, ISSN 0033-3158, 3/2013, Volume 226, Issue 2, pp. 357 - 369
Studies have shown the involvement of angiotensin II (Ang II) in neurobehavioral aspects, but the exact role of Ang II in memory is still ambiguous.This study... 
Neurosciences | Biomedicine | PD123,319 | Candesartan | Memory | Pharmacology/Toxicology | Psychiatry | Angiotensin receptors | CONVERTING ENZYME | PSYCHIATRY | ALZHEIMERS-DISEASE | RECEPTOR | FACILITATION | NEUROSCIENCES | IMPAIRMENT | HIPPOCAMPUS | PHARMACOLOGY & PHARMACY | MICE | LONG-TERM POTENTIATION | HYPERTENSION | Memory - drug effects | Angiotensin II - pharmacology | Tetrazoles - pharmacology | Cerebrovascular Circulation - drug effects | Angiotensin Receptor Antagonists - pharmacology | Rats | Male | Acetylcholine - metabolism | Imidazoles - pharmacology | Rats, Sprague-Dawley | Hippocampus - metabolism | Animals | Cholinesterase Inhibitors - pharmacology | Piperidines - pharmacology | Adenosine Triphosphate - metabolism | Benzimidazoles - pharmacology | Synaptic Transmission - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Melatonin - pharmacology | Acetylcholinesterase - metabolism | Indans - pharmacology | Psychological aspects | Brain | Angiotensin | Cerebral circulation | Neuropsychopharmacology | Physiological aspects | Neural transmission | Research | Neurotrophic functions | Hypertension | Clinical trials | T cell receptors | Drug therapy | Psychopharmacology
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4. Full Text Dopaminergic modulation of ganglion‐cell photoreceptors in rat
by Van Hook, Matthew J and Wong, Kwoon Y and Berson, David M
European Journal of Neuroscience, ISSN 0953-816X, 02/2012, Volume 35, Issue 4, pp. 507 - 518
A novel class of photoreceptors, the intrinsically photosensitive retinal ganglion cells (ipRGCs), express the photopigment melanopsin and drive... 
melanopsin | cyclic AMP (cAMP) | D1 receptor | intrinsically photosensitive retinal ganglion cells (ipRGCs) | retina | Retina | Intrinsically photosensitive retinal ganglion cells (ipRGCs) | Cyclic AMP (cAMP) | Melanopsin | PROTEIN-KINASE-A | TIGER SALAMANDER RETINA | IMMUNOHISTOCHEMICAL LOCALIZATION | RETINOHYPOTHALAMIC TRACT | CLASS-III MYOSIN | NEUROSCIENCES | DROSOPHILA PHOTORECEPTORS | RECEPTOR ACTIVATION | CALMODULIN-BINDING | DEPENDENT MECHANISM | ADENYLATE-CYCLASE | Actins - metabolism | Male | Actins - genetics | Visual Pathways - physiology | Rod Opsins - genetics | Retina - cytology | Light Signal Transduction - drug effects | Light | Rod Opsins - metabolism | Tetrodotoxin - pharmacology | Cyclic AMP - metabolism | Light Signal Transduction - physiology | Dopamine - metabolism | Membrane Potentials - drug effects | Dopamine Agonists - pharmacology | Retinal Ganglion Cells - physiology | Colforsin - pharmacology | Receptors, Dopamine - metabolism | Cells, Cultured | Dopamine - pharmacology | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Membrane Potentials - physiology | Rats, Sprague-Dawley | 1-Methyl-3-isobutylxanthine - pharmacology | Gene Expression Regulation - drug effects | Patch-Clamp Techniques | Pyrroles - pharmacology | Animals | Visual Pathways - drug effects | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Quinpirole - pharmacology | Carbazoles - pharmacology | In Vitro Techniques | Photic Stimulation | Photoreceptor Cells - physiology | Receptors, Dopamine - genetics | Circadian rhythms | Melatonin | Pineal gland | photopigments | Light effects | Neuromodulation | quinpirole | Retinal ganglion cells | Dopamine D1 receptors | Coding | Forskolin | Amacrine cells | Photoreceptors | Dendrites | Dopamine D2 receptors | Dopamine receptors | Reflexes
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5. Full Text Melatonin: Pharmacology, Functions and Therapeutic Benefits
by Sylvie Tordjman and Sylvie Chokron and Richard Delorme and Annaelle Charrier and Eric Bellissant and Nemat Jaafari and Claire Fougerou
Current Neuropharmacology, ISSN 1570-159X, 04/2017, Volume 15, Issue 3, pp. 434 - 443
Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.),... 
Biomarker | Melatonin | Synchronizer | Clinical application | Central and peripheral oscillators | Adaptation to external and internal environment | Prevention and treatment | Sleep-wake rhythm | Biological clocks | clinical application | OXIDATIVE STRESS | SERUM MELATONIN | CIRCADIAN-RHYTHMS | prevention and treatment | PINEAL-GLAND | COLON CARCINOGENESIS | PRETERM INFANTS | biomarker | EXPRESSION CLONING | N-ACETYLTRANSFERASE | NEUROSCIENCES | RHYTHM SLEEP DISORDERS | sleep-wake rhythm | biological clocks | synchronizer | CEREBRAL-ARTERY OCCLUSION | PHARMACOLOGY & PHARMACY | melatonin | central and peripheral oscillators | Neonates | Mental disorders | Liver | Environmental changes | Antioxidants | Bone growth | Physiology | Children | Pancreas | Circadian rhythms | Free radicals | Kidneys | Therapeutic applications | Fetuses | Detoxification | Circadian rhythm | Oscillators | Bone mass | Reviews | Body mass | Biomarkers | Pharmacokinetics | Cardiovascular diseases | Osteogenesis | Life Sciences
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6. Full Text Physiology and pharmacology of melatonin in relation to biological rhythms
by Zawilska, Jolanta B and Skene, Debra J and Arendt, Josephine
Pharmacological Reports, ISSN 1734-1140, 05/2009, Volume 61, Issue 3, pp. 383 - 410
Melatonin is an evolutionarily conserved molecule that serves a time-keeping function in various species. In vertebrates, melatonin is produced predominantly... 
AANAT | retina | light | circadian rhythm | melatonin | melatonin receptors | photoperiod | pineal gland | circadian rhythm sleep disorders | Melatonin receptors | Melatonin | Circadian rhythm sleep disorders | Light | Pineal gland | Retina | Photoperiod | Circadian rhythm | SERUM MELATONIN | RECEPTOR MESSENGER-RNA | CHICK PINEAL-GLAND | PLASMA MELATONIN | TRYPTOPHAN-HYDROXYLASE | BRIGHT LIGHT | SEROTONIN N-ACETYLTRANSFERASE | PHASE RESPONSE CURVE | PHARMACOLOGY & PHARMACY | HUMAN CIRCADIAN-RHYTHMS | MAJOR DEPRESSIVE DISORDER | Depression - physiopathology | Sleep Wake Disorders - drug therapy | Humans | Receptors, Melatonin - classification | Melatonin - physiology | Suprachiasmatic Nucleus - physiology | Depression - drug therapy | Light Signal Transduction | Suprachiasmatic Nucleus - metabolism | Molecular Structure | Seasons | Sleep Wake Disorders - physiopathology | Receptors, Melatonin - antagonists & inhibitors | Pineal Gland - physiology | Circadian Rhythm - physiology | Receptors, Melatonin - metabolism | Arylalkylamine N-Acetyltransferase - physiology | Animals | Pineal Gland - physiopathology | Receptors, Melatonin - agonists | Melatonin - therapeutic use | Melatonin - biosynthesis | Circadian Rhythm - drug effects | Melatonin - pharmacology
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7. Full Text Potential drug interactions with melatonin
by Papagiannidou, Eleni and Skene, Debra J and Ioannides, Costas
Physiology & Behavior, ISSN 0031-9384, 2014, Volume 131, pp. 17 - 24
Abstract Possible interactions of melatonin with concurrently administered drugs were investigated in in vitro studies utilising human hepatic... 
Psychiatry | Melatonin | 5-Methoxypsoralen | Drug interactions | 17-Ethinyloestradiol | CYP1A2 | MENSTRUAL-CYCLE | CIRCADIAN-RHYTHMS | FLUVOXAMINE | HUMANS | BIOAVAILABILITY | IN-VITRO | METABOLISM | LIVER | BEHAVIORAL SCIENCES | PSYCHOLOGY, BIOLOGICAL | ORAL-CONTRACEPTIVES | Estrogens - pharmacology | Antineoplastic Agents, Hormonal - pharmacology | Rats, Wistar | Humans | Microsomes, Liver - metabolism | Middle Aged | Analgesics, Non-Narcotic - pharmacology | Male | Antidepressive Agents, Second-Generation - pharmacology | Methoxsalen - analogs & derivatives | Fluvoxamine - pharmacology | Diazepam - pharmacology | Central Nervous System Depressants - pharmacology | Melatonin - analogs & derivatives | Animals | Drug Interactions | Acetaminophen - pharmacology | Methoxsalen - pharmacology | Microsomes, Liver - drug effects | Melatonin - metabolism | Tamoxifen - pharmacology | Hypnotics and Sedatives - pharmacology | Melatonin - pharmacology | Complications and side effects | Hydroxylation | Cytochrome P-450
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8. Full Text Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses
by Cicero, Arrigo F. G and Colletti, Alessandro
High Blood Pressure & Cardiovascular Prevention, ISSN 1120-9879, 9/2015, Volume 22, Issue 3, pp. 203 - 213
Beyond the well-known effects on blood pressure (BP) of the dietary approaches to stop hypertension (DASH) and the Mediterranean diets, a large number of... 
Hypertension | Medicine & Public Health | Dietary supplements | Pharmacotherapy | Blood pressure (BP) | Clinical evidence | Review | Cardiology | Nutraceuticals | Meta-Analysis as Topic | Plant Extracts - pharmacology | Humans | Minerals - pharmacology | Stilbenes - pharmacology | Amino Acids - pharmacology | Carotenoids - pharmacology | Vitamins - pharmacology | Ubiquinone - pharmacology | Hypertension - prevention & control | Blood Pressure - drug effects | Flavonoids - pharmacology | Fruit and Vegetable Juices | Dietary Supplements - adverse effects | Ubiquinone - analogs & derivatives | Fatty Acids, Unsaturated - pharmacology | Clinical Trials as Topic | Probiotics - pharmacology | Beta vulgaris | Magnesium - pharmacology | Potassium - pharmacology | Peptides - pharmacology | Garlic | Proteins - pharmacology | Melatonin - pharmacology | Prevention | Usage | Functional foods | Clinical trials | Blood pressure | Regulation | Health aspects | Meta-analysis
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