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Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific... 
UNFOLDED PROTEIN RESPONSE | PATHWAY | ER STRESS | HOST-DEFENSE | ENDOPLASMIC-RETICULUM STRESS | FRANCISELLA-TULARENSIS INFECTION | IMMUNOLOGY | LIVE VACCINE STRAIN | INFLAMMATORY RESPONSE | NEGATIVE REGULATOR | SYSTEMS BIOLOGY | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 499 - 510
Journal Article
Immunity, ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 275 - 284
Epidermal growth factor receptor (EGFR) is known to be critically involved in tissue development and homeostasis as well as in the pathogenesis of cancer. Here... 
CETUXIMAB | RESPONSES | TOLERANCE | MAST-CELLS | DISEASE | MODEL | IMMUNOLOGY | CARCINOMA | EXPRESSION | METASTATIC COLORECTAL-CANCER | EGF RECEPTOR | Forkhead Transcription Factors - immunology | Cell Communication - immunology | Receptor, Epidermal Growth Factor - genetics | T-Lymphocytes, Regulatory - metabolism | Humans | Colitis - pathology | Homeodomain Proteins - immunology | Amphiregulin | Glycoproteins - pharmacology | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Melanoma, Experimental - immunology | EGF Family of Proteins | Colitis - chemically induced | Peptide Fragments - immunology | Mast Cells - metabolism | Colitis - immunology | Glycoproteins - genetics | Mast Cells - immunology | Receptor, Epidermal Growth Factor - immunology | Peptide Fragments - administration & dosage | Glycoproteins - antagonists & inhibitors | Intercellular Signaling Peptides and Proteins - genetics | Melanoma, Experimental - pathology | Antibodies, Neutralizing - pharmacology | Membrane Proteins - immunology | Mice, Transgenic | Forkhead Transcription Factors - genetics | Mast Cells - drug effects | Homeodomain Proteins - genetics | Gene Expression Regulation - drug effects | Membrane Proteins - administration & dosage | Glycoproteins - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Melanoma, Experimental - genetics | Signal Transduction - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Lymphocyte Activation - drug effects | Colitis - metabolism | Mice | Intercellular Signaling Peptides and Proteins - immunology | Epidermal growth factor | Universities and colleges | T cells | Analysis | Vaccination | Cells | Flow cytometry | Cytokines | Cloning | Melanoma | Kinases | Experiments | Cancer therapies | Rodents | Bone marrow | Software | Tumors | Cancer | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2012, Volume 122, Issue 11, pp. 3965 - 3976
Psoriasis is a chronic inflammatory disorder of the skin affecting approximately 2% of the world's population. Accumulating evidence has revealed that the... 
GENERALIZED PUSTULAR PSORIASIS | MEDICINE, RESEARCH & EXPERIMENTAL | INFLAMMATORY SKIN-DISEASE | FAMILY-MEMBERS | MOUSE MODEL | DELTA-T-CELLS | NF-KAPPA-B | AUTOINFLAMMATORY DISEASE | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | CUTTING EDGE | TRANSGENIC MICE | Cell Communication - immunology | Interleukin-1 - genetics | Membrane Glycoproteins - metabolism | Dermatitis - immunology | Dendritic Cells - immunology | Receptors, Interleukin-1 - genetics | Interleukin-17 - immunology | Dendritic Cells - pathology | Interleukins - metabolism | Interleukin-23 - genetics | Interleukins - genetics | Psoriasis - genetics | Interleukin-23 - metabolism | Psoriasis - pathology | Interleukins - immunology | Toll-Like Receptor 7 - immunology | Interleukin-1 - immunology | Psoriasis - metabolism | Membrane Glycoproteins - immunology | Dendritic Cells - metabolism | Psoriasis - immunology | Toll-Like Receptor 7 - genetics | Interleukin-1 - metabolism | Toll-Like Receptor 7 - metabolism | Dermatitis - genetics | Receptors, Interleukin-1 - immunology | Interleukin-17 - genetics | Cell Communication - genetics | Interleukin-23 - immunology | Keratinocytes - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Dermatitis - pathology | Interleukin-17 - metabolism | Keratinocytes - pathology | Animals | Keratinocytes - metabolism | Mice | Dermatitis - metabolism | Psoriasis | Interleukins | Keratinocytes | Genetic aspects | Dosage and administration | Diagnosis | Drug therapy | Index Medicus | Abridged Index Medicus | TLR7 protein | Dendritic cells | Mesenchyme | Interleukin 22 | Interleukin 23 | Leukocytes (neutrophilic) | Interleukin 1 receptors | Dermatitis | Inflammatory diseases | Interleukin 17 | Toll-like receptors | Skin
Journal Article
Blood, ISSN 0006-4971, 08/2010, Volume 116, Issue 6, pp. 935 - 944
Type 1 T regulatory (Tr1) cells suppress immune responses in vivo and in vitro and play a key role in maintaining tolerance to self- and non-self-antigens.... 
G MOLECULE | IN-VITRO | CD16(+) MONOCYTES | HUMAN DENDRITIC CELLS | HLA-G EXPRESSION | CD4(+) | PERIPHERAL-BLOOD | HEMATOLOGY | MACROPHAGE ACTIVATION | IL-10 | MYELOMONOCYTIC CELLS | Cell Communication - immunology | T-Lymphocytes, Regulatory - metabolism | Membrane Glycoproteins - metabolism | Monocytes - cytology | Dendritic Cells - immunology | Humans | Monocytes - metabolism | Monocytes - immunology | HLA Antigens - genetics | T-Lymphocytes, Regulatory - immunology | Histocompatibility Antigens Class I - metabolism | Signal Transduction - immunology | Flow Cytometry | Immune Tolerance - immunology | Gene Expression - immunology | T-Lymphocytes, Regulatory - cytology | Interleukin-10 - metabolism | Interleukin-10 - secretion | Membrane Glycoproteins - immunology | Receptors, Immunologic - immunology | Interleukin-12 - secretion | Dendritic Cells - metabolism | Histocompatibility Antigens Class I - immunology | HLA Antigens - immunology | Immunophenotyping | Histocompatibility Antigens Class I - genetics | Interleukin-12 - metabolism | HLA-G Antigens | HLA Antigens - metabolism | Membrane Glycoproteins - genetics | Cell Differentiation - immunology | Dendritic Cells - cytology | Receptors, Immunologic - genetics | Interleukin-10 - immunology | Receptors, Immunologic - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1893 - 1898
Ebola viruses cause hemorrhagic disease in humans and nonhuman primates with high fatality rates. These viruses pose a significant health concern worldwide due... 
T lymphocytes | Ebola virus | B lymphocytes | Vaccination | Antibodies | Primates | Monoclonal antibodies | Viruses | Infections | Blood | RESPONSES | PROPHYLAXIS | IMMUNITY | HEMORRHAGIC-FEVER | HAMSTERS | MULTIDISCIPLINARY SCIENCES | VACCINE PROTECTION | INFECTION | MACAQUES | MARBURG | MODEL | Recombinant Fusion Proteins - immunology | Liver - pathology | Spleen - immunology | Hemorrhagic Fever, Ebola - prevention & control | Immunoglobulin G - blood | Humans | Macaca fascicularis | Male | Ebolavirus - genetics | Antibodies, Viral - blood | Ebolavirus - immunology | Liver - immunology | Lymphocytes - immunology | Time Factors | Immunoglobulin G - immunology | Marburgvirus - immunology | Ebola Vaccines - immunology | Hemorrhagic Fever, Ebola - immunology | Membrane Glycoproteins - immunology | Spleen - pathology | Recombinant Fusion Proteins - administration & dosage | Cytokines - blood | Cytokines - immunology | Viral Envelope Proteins - genetics | Enzyme-Linked Immunosorbent Assay | Vesicular stomatitis Indiana virus - genetics | Ebola Vaccines - administration & dosage | Reverse Transcriptase Polymerase Chain Reaction | Viral Load - genetics | Marburgvirus - genetics | Membrane Glycoproteins - genetics | Spleen - parasitology | Hemorrhagic Fever, Ebola - blood | Animals | Recombinant Fusion Proteins - genetics | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Liver - parasitology | Vesicular stomatitis Indiana virus - immunology | Immunization | Immunology | T cell receptors | Glycoproteins | Vaccines | Monkeys & apes | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2013, Volume 110, Issue 51, pp. E4997 - E5005
Human cytomegalovirus (HCMV) can cause serious morbidity/ mortality in transplant patients, and congenital HCMV infection can lead to birth defects. Developing... 
Antiviral antibody | Monoclonal antibody | NATURAL INFECTION | VIRUS-INFECTION | LINKED-IMMUNOSORBENT-ASSAY | MULTIDISCIPLINARY SCIENCES | PRIMARY INFECTION | SMOOTH-MUSCLE | ORGAN TRANSPLANT RECIPIENTS | CMV-HYPERIMMUNE GLOBULIN | antiviral antibody | EPITHELIAL-CELLS | ENDOTHELIAL-CELLS | monoclonal antibody | ANTIBODY-RESPONSE | Complementarity Determining Regions - genetics | Humans | Multiprotein Complexes - genetics | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Immunoglobulin Light Chains - genetics | Antibodies, Neutralizing - immunology | Cytomegalovirus Infections - prevention & control | Female | Membrane Glycoproteins - immunology | Immunoglobulin Heavy Chains - immunology | Antibodies, Monoclonal - immunology | Cytomegalovirus Vaccines - genetics | Immunoglobulin Light Chains - immunology | Cytomegalovirus - genetics | Rabbits | Viral Envelope Proteins - genetics | Antibodies, Neutralizing - genetics | Membrane Glycoproteins - genetics | Antibodies, Monoclonal - genetics | Cytomegalovirus - immunology | Animals | Complementarity Determining Regions - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Cytomegalovirus Vaccines - immunology | Antibodies, Viral - genetics | Immunoglobulin Heavy Chains - genetics | Multiprotein Complexes - immunology | Antigens | Immunology | Monoclonal antibodies | Viruses | Glycoproteins | Vaccines | Gene expression | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2010, Volume 11, Issue 2, pp. 141 - 147
Journal Article