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Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 01/2020, Volume 177, p. 112891
Despite many efforts, drug discovery pipeline is still a highly inefficient process. Nowadays, when combinatorial chemistry enables to synthesize hundreds of... 
Micellar liquid chromatography | Immobilized artificial membrane chromatography | Blood–brain barrier | Electrokinetic chromatography
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2019, Volume 10, Issue 1, pp. 2649 - 11
In human and other mammalian cells, transport of L-lactate across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the SLC16... 
ANCILLARY PROTEIN | MONOCARBOXYLATE TRANSPORTER | TRANSMEMBRANE HELICES | RECOGNITION | PROTEIN SECONDARY STRUCTURE | LACTOSE PERMEASE | MULTIDISCIPLINARY SCIENCES | MCT1 | BINDING-SITE | IDENTIFICATION | EXPRESSION | Membranes | Plasma membranes | Homology | Ligands | Pharmacology | Lactic acid | Transport | Metabolism | Transporter | Crystal structure | Conformation | Mammalian cells
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2019, Volume 26, Issue 1, pp. 328 - 342
Efficient cellular delivery of biologically active molecules is one of the key factors that affect the discovery and development of novel drugs. The plasma... 
pro-drugs | Cellular uptake | delivery systems | plasma membrane | disulfide exchange | HEPATOCELLULAR-CARCINOMA CELLS | DRUG-DELIVERY | GLUCOSE TRANSPORTERS | MOLECULAR TRANSPORTERS | PROTEIN TRANSDUCTION | NUCLEIC-ACIDS | PHENYLBORONIC ACID | IN-VIVO | INTRACELLULAR DELIVERY | PHARMACOLOGY & PHARMACY | PENETRATING PEPTIDES
Journal Article
Scientific reports, ISSN 2045-2322, 06/2019, Volume 9, Issue 1, pp. 8278 - 9
Gold nanoparticles (AuNPs) have been extensively used as nanomaterials for theranostic applications due to their multifunctional characteristics in... 
Nanoparticles | Neuroimaging | Gold | Brain | Bioluminescence | Intravenous administration | Blood-brain barrier | Nanomaterials | Genetic engineering | Exosomes | Nanotechnology | Mammalian cells
Journal Article
Biomedical Chromatography, ISSN 0269-3879, 12/2019, Volume 33, Issue 12, pp. e4692 - n/a
Ginkgo diterpene lactone (GDL) is the raw material for ginkgo diterpene lactone meglumine injection, which is used for treating cerebral ischemia. The aims of... 
phosphatidylserine | ginkgo diterpene lactones | subcellular distribution | cellular pharmacokinetics | mitochondria membrane potential | oxygen–glucose deprivation and reoxygenation | P‐glycoprotein | Mass spectrometry | Liquid chromatography | Raw materials
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 2155 - 12
Anthracyclines interact with DNA and topoisomerase II as well as with cell membranes, and it is these latter interactions that can cause an increase in their... 
MULTIDRUG-RESISTANT | MOLECULAR-DYNAMICS | DAUNOMYCIN | ANTIBIOTICS | EFFLUX | STRUCTURAL REQUIREMENTS | KINETICS | MULTIDISCIPLINARY SCIENCES | DOXORUBICIN | CARDIOTOXICITY | ADRIAMYCIN | DNA topoisomerase (ATP-hydrolysing) | Daunorubicin | Anthracycline | Computer applications | Cytotoxicity | Cell membranes | Epirubicin | Doxorubicin | Lipid bilayers
Journal Article
International Journal of Peptide Research and Therapeutics, ISSN 1573-3149, 12/2019, Volume 25, Issue 4, pp. 1279 - 1290
Escherichia coli is one of the simplest hosts which is widely being used to express heterologous proteins. However, without appropriate signal peptide, this... 
Life Sciences | Biochemistry, general | Polymer Sciences | Pharmaceutical Sciences/Technology | Molecular Medicine | Pharmacology/Toxicology | Animal Anatomy / Morphology / Histology | Bioinformatics | E. coli | Signal peptides | NS3 -gp96 | Antigens | Medical colleges | Peptides | Analysis | Escherichia coli | Hepatitis C virus | T cells | Health aspects | Recombinant proteins
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 7419 - 9
Biomimetic nanoparticles (NPs) have been actively studied for their biological compatibility due to its distinguished abilities viz. long-term circulation, low... 
NANOPARTICLES | CLEARANCE | CIRCULATION | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | STIMULI | TUMOR MICROENVIRONMENT | PET | Nanoparticles | Toxicity | Erythrocytes | Biocompatibility | Cell membranes | Macrophages | Silica | Phagocytosis | Immunosuppressive agents | Blood
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4113 - 9
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3353 - 13
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 120 - 15
Journal Article