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The Journal of neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 9, pp. 3953 - 3966
Down syndrome (DS) is associated with neurological complications, including cognitive deficits that lead to impairment in intellectual functioning. Increased... 
Protein Binding - genetics | Electric Stimulation | Cell Count | Male | GABA Modulators - therapeutic use | Learning Disorders - etiology | Hyperkinesis - drug therapy | Neurogenesis - genetics | Long-Term Potentiation - drug effects | Protein Binding - drug effects | Exploratory Behavior - drug effects | Reflex, Startle - drug effects | Imidazoles - therapeutic use | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Mice, Transgenic | Hippocampus - pathology | Imidazoles - pharmacology | Psychomotor Performance - drug effects | Hyperkinesis - etiology | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Analysis of Variance | Seizures - etiology | Glutamate Decarboxylase - metabolism | Mice | Receptors, GABA-A - metabolism | Benzodiazepines - therapeutic use | Tritium - pharmacokinetics | Sensory Gating - drug effects | Reflex - genetics | Reflex - drug effects | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Ki-67 Antigen | Reaction Time - drug effects | GABA Modulators - pharmacology | Neurons - physiology | Down Syndrome - complications | Membrane Proteins - metabolism | Neurogenesis - drug effects | Neurons - drug effects | Cues | Down Syndrome - pathology | Benzodiazepines - pharmacology | Acoustic Stimulation | Mice, Inbred C57BL | Learning Disorders - drug therapy | Long-Term Potentiation - genetics | Biophysics | Maze Learning - drug effects | Rotarod Performance Test | Animals | Carrier Proteins - metabolism | Down Syndrome - drug therapy | Cell Proliferation - drug effects | Index Medicus
Journal Article
Nature neuroscience, ISSN 1546-1726, 01/2013, Volume 16, Issue 2, pp. 183 - 192
...-Cl- co-transporter KCC2, impairing Cl- homeostasis in rat spinal lamina I neurons. Restoring the anion equilibrium potential reversed the morphine-induced hyperalgesia without affecting tolerance... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain-Derived Neurotrophic Factor - genetics | Biophysical Phenomena - drug effects | Motor Activity - drug effects | Male | Ribosome Inactivating Proteins, Type 1 - pharmacology | Touch | CD11b Antigen - genetics | Microglia - physiology | Time Factors | Chlorides - metabolism | Pain Threshold - drug effects | Biophysical Phenomena - genetics | Vocalization, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Homeostasis - drug effects | Protein Synthesis Inhibitors - pharmacology | Spinal Cord - cytology | Neurons - drug effects | Membrane Potentials - drug effects | Hot Temperature - adverse effects | Microglia - drug effects | Mice, Inbred C57BL | Rats | Mice, Transgenic | Signal Transduction - genetics | Down-Regulation - drug effects | Rats, Sprague-Dawley | Symporters - metabolism | Gene Expression Regulation - drug effects | Narcotics - administration & dosage | Patch-Clamp Techniques | Rotarod Performance Test | Animals | Hyperalgesia - drug therapy | Signal Transduction - drug effects | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Mice | CD11b Antigen - metabolism | Receptors, Purinergic P2X4 - metabolism | Morphine - administration & dosage | Receptors, Purinergic P2X4 - genetics | Ion Channel Gating - drug effects | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2011, Volume 301, Issue 3, pp. 587 - 600
Transient receptor potential (TRP) ankyrin 1 (TRPA1) is a Ca2+-permeant, nonselective cationic channel... 
Transient receptor potential vanilloid 1 | Synaptic transmission | Patchclamp | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Hyperalgesia - chemically induced | Calcium - metabolism | Capsaicin - pharmacology | Nociception - physiology | Ganglia, Spinal - cytology | Nociceptive Pain - chemically induced | Calcium Channels - physiology | Protein Kinase C - metabolism | Oocytes - drug effects | Behavior, Animal - drug effects | Synaptic Transmission - drug effects | Ankyrins - agonists | Membrane Potentials - drug effects | Calcium - pharmacology | TRPC Cation Channels | Colforsin - pharmacology | Oocytes - metabolism | Rats | Rats, Sprague-Dawley | 1-Methyl-3-isobutylxanthine - pharmacology | Tachyphylaxis - physiology | Mice, Knockout | Nociceptive Pain - physiopathology | Spermine - pharmacology | Mice | Inhibitory Postsynaptic Potentials - drug effects | Electrophysiological Phenomena - drug effects | Hydrogen-Ion Concentration | Maleimides - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Isocyanates - pharmacology | Miniature Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Trigeminal Caudal Nucleus - cytology | Neurons - physiology | Transient Receptor Potential Channels - physiology | Neurons - drug effects | Action Potentials - drug effects | Miniature Postsynaptic Potentials - physiology | Cyclic AMP-Dependent Protein Kinases - metabolism | Xenopus laevis | Electrophysiological Phenomena - physiology | Inhibitory Postsynaptic Potentials - physiology | Ankyrins - physiology | Allyl Compounds - pharmacology | Membrane Potentials - physiology | Mice, Inbred Strains | Transient Receptor Potential Channels - agonists | TRPV Cation Channels - genetics | Hyperalgesia - physiopathology | Action Potentials - physiology | Animals | TRPA1 Cation Channel | Ion Channel Gating - drug effects | Nociception | Neural transmission | Ion channels | Research | Properties | Index Medicus | synaptic transmission | patch-clamp | Nervous System Cell Biology | transient receptor potential vanilloid 1
Journal Article
The Journal of neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 21, pp. 7152 - 7167
... (Set domain, bifurcated 1)/Eset/Kmt1e are associated with repressive chromatin remodeling and expressed in adult brain, but potential effects on neuronal function and behavior remain unexplored... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Chromatin - metabolism | Immobility Response, Tonic - physiology | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Fear - drug effects | Green Fluorescent Proteins - genetics | Protein Methyltransferases - metabolism | Neurons - ultrastructure | Excitatory Amino Acid Agents - pharmacology | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Excitatory Postsynaptic Potentials - genetics | Animals, Newborn | Membrane Potentials - drug effects | Adaptation, Ocular - genetics | Maze Learning - physiology | Food Preferences - drug effects | Histone-Lysine N-Methyltransferase | Affect - physiology | Behavior, Animal - physiology | Mice, Transgenic | Avoidance Learning - physiology | Avoidance Learning - drug effects | Mice | Membrane Potentials - genetics | Electroshock - adverse effects | Age Factors | Food Preferences - physiology | Protein Methyltransferases - genetics | Adaptation, Ocular - drug effects | Motor Activity - drug effects | Fear - physiology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Receptors, N-Methyl-D-Aspartate - genetics | Exploratory Behavior - physiology | Transfection - methods | Neurons - physiology | Chromatin Immunoprecipitation - methods | Immobility Response, Tonic - drug effects | Neurons - drug effects | Sucrose - administration & dosage | Affect - drug effects | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Gene Expression Regulation - physiology | Hippocampus - cytology | Maze Learning - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Gene Expression Regulation - drug effects | Motor Activity - genetics | Animals | Sweetening Agents - administration & dosage | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 84, pp. 25 - 41
Abstract Curcumin (Cur) has been demonstrated to have wide pharmacological window including anti-oxidant and anti-inflammatory properties. However,... 
Advanced Basic Science | Dentistry | Photodegradation | Phototoxicity | Curcumin | Apoptosis/necrosis | Photoprotection | Nanoformulation | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | DNA Breaks - drug effects | NIH 3T3 Cells | Reactive Oxygen Species - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Keratinocytes - radiation effects | Membrane Potential, Mitochondrial - radiation effects | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | DNA Breaks - radiation effects | Photosensitizing Agents - pharmacology | Ultraviolet Rays | Protective Agents - pharmacology | Cytoprotection - drug effects | Oxidative Stress - radiation effects | Signal Transduction - radiation effects | Proto-Oncogene Proteins c-akt - metabolism | Keratinocytes - enzymology | Keratinocytes - ultrastructure | Cell Membrane - drug effects | Cell Membrane - radiation effects | Cell Line | Cell Survival - drug effects | Lactic Acid - chemistry | RNA, Messenger - genetics | Curcumin - pharmacology | Absorption, Radiation | Cell Survival - radiation effects | Animals | Cell Cycle Checkpoints - radiation effects | Keratinocytes - drug effects | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Polyglycolic Acid - chemistry | Drug Liberation | Mice | Molecular Docking Simulation | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Nanoparticles | Genetic research | Analysis | Index Medicus | Biotechnology | Phosphorylation | Cascades | Sunlight | Exposure | Biological | Apoptosis
Journal Article