X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (128152) 128152
Publication (16661) 16661
Newsletter (934) 934
Book Review (854) 854
Book Chapter (793) 793
Book / eBook (678) 678
Newspaper Article (219) 219
Conference Proceeding (171) 171
Magazine Article (145) 145
Dissertation (78) 78
Data Set (25) 25
Reference (15) 15
Trade Publication Article (14) 14
Paper (8) 8
Web Resource (6) 6
Government Document (1) 1
Journal / eJournal (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (80447) 80447
index medicus (49769) 49769
humans (47794) 47794
membrane potentials - drug effects (35939) 35939
rats (27145) 27145
male (26579) 26579
mice (20481) 20481
female (18924) 18924
in vitro techniques (16904) 16904
neurosciences (15353) 15353
apoptosis (14899) 14899
biochemistry & molecular biology (14393) 14393
proteins (14140) 14140
cells, cultured (13952) 13952
research article (13815) 13815
cell biology (13484) 13484
physiology (13461) 13461
research (12902) 12902
pharmacology & pharmacy (12426) 12426
membrane potentials - physiology (11326) 11326
multidisciplinary sciences (11089) 11089
calcium - metabolism (10963) 10963
dose-response relationship, drug (10909) 10909
apoptosis - drug effects (10083) 10083
medicine (9732) 9732
patch-clamp techniques (9496) 9496
membrane potentials (9362) 9362
expression (9057) 9057
cells (8737) 8737
physiological aspects (8661) 8661
kinetics (8506) 8506
cell line, tumor (8469) 8469
cell line (8402) 8402
membranes (8110) 8110
membrane potential, mitochondrial - drug effects (8079) 8079
neurons - drug effects (8050) 8050
analysis (7956) 7956
science (7844) 7844
time factors (7810) 7810
article (7753) 7753
cancer (7718) 7718
activation (7697) 7697
rats, sprague-dawley (7607) 7607
mitochondria (7504) 7504
oxidative stress (7447) 7447
electrophysiology (7408) 7408
cell membrane - metabolism (7242) 7242
biology (7089) 7089
gene expression (6926) 6926
oncology (6792) 6792
in-vitro (6587) 6587
signal transduction (6540) 6540
cell membrane - drug effects (6419) 6419
membrane proteins (6116) 6116
reactive oxygen species - metabolism (6058) 6058
health aspects (6051) 6051
mitochondria - drug effects (6020) 6020
action potentials - drug effects (6013) 6013
biochemistry (5849) 5849
neurons (5744) 5744
inhibition (5739) 5739
rats, wistar (5667) 5667
neurons - physiology (5657) 5657
mitochondria - metabolism (5609) 5609
membrane proteins - metabolism (5596) 5596
cell survival - drug effects (5468) 5468
rodents (5413) 5413
membrane (5403) 5403
calcium (5361) 5361
phosphorylation (5103) 5103
membrane potential (4939) 4939
biophysics (4768) 4768
genetic aspects (4767) 4767
electric stimulation (4704) 4704
permeability (4531) 4531
adult (4500) 4500
kinases (4498) 4498
sodium - metabolism (4481) 4481
microbiology (4344) 4344
signal transduction - drug effects (4322) 4322
guinea pigs (4307) 4307
mice, inbred c57bl (4271) 4271
potassium - metabolism (4243) 4243
immunology (4235) 4235
hydrogen-ion concentration (4209) 4209
toxicology (4088) 4088
lipids (4055) 4055
studies (4053) 4053
calcium - pharmacology (4041) 4041
mutation (4026) 4026
flow cytometry (3897) 3897
membrane proteins - genetics (3884) 3884
medicine, research & experimental (3882) 3882
middle aged (3878) 3878
cell membranes (3857) 3857
cell proliferation - drug effects (3813) 3813
brain (3805) 3805
rabbits (3794) 3794
molecular sequence data (3788) 3788
inflammation (3784) 3784
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (418) 418
UofT at Mississauga - Stacks (71) 71
UTL at Downsview - May be requested (46) 46
Engineering & Comp. Sci. - Stacks (30) 30
Earth Sciences (Noranda) - Stacks (26) 26
UofT at Scarborough - Stacks (22) 22
Collection Dvlpm't (Acquisitions) - Closed Orders (19) 19
Collection Dvlpm't (Acquisitions) - Vendor file (18) 18
Online Resources - Online (18) 18
Chemistry (A D Allen) - Stacks (9) 9
Trinity College (John W Graham) - Stacks (6) 6
Physics - Stacks (5) 5
UofT at Scarborough - Withdrawn (3) 3
Dentistry (Harry R Abbott) - Stacks (2) 2
Engineering & Comp. Sci. - Reference (2) 2
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
Victoria University E.J. Pratt - Oversize (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Credit Valley Hospital - Reserve desk (1) 1
Dentistry (Harry R Abbott) - Withdrawn (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - May be requested in 6-10 wks (1) 1
Gerstein Science - Missing (1) 1
Gerstein Science - Reserve desk (1) 1
Humber River Regional Hospital - Finch Stacks (1) 1
Media Commons - Microtexts (1) 1
Physics - Course Reserves (1) 1
Physics - Missing (1) 1
Scarborough Hospital - May be requested (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Holland Reference (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Reference (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
Toronto East General Hospital - Stacks (1) 1
Trillium Health Centre - Reserve desk (1) 1
Trinity College (John W Graham) - Storage (1) 1
UofT at Mississauga - Circulation Desk (1) 1
UofT at Mississauga - Missing (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - Birchmount (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (127839) 127839
Russian (1413) 1413
Chinese (419) 419
German (330) 330
French (268) 268
Japanese (263) 263
Ukrainian (88) 88
Spanish (78) 78
Polish (44) 44
Italian (42) 42
Portuguese (18) 18
Czech (14) 14
Korean (10) 10
Slovak (9) 9
Bulgarian (8) 8
Dutch (7) 7
Danish (5) 5
Serbian (5) 5
Romanian (4) 4
Croatian (3) 3
Hungarian (3) 3
Hebrew (2) 2
Swedish (2) 2
Turkish (2) 2
Arabic (1) 1
Finnish (1) 1
Greek (1) 1
Lithuanian (1) 1
Norwegian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Neuroscience, ISSN 1097-6256, 02/2013, Volume 16, Issue 2, pp. 183 - 192
A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the gold-standard analgesic morphine and other opiates. We found that... 
LAMINA-I NEURONS | NEUROTROPHIC FACTOR | P2X RECEPTORS | DOWN-REGULATION | OPIOID-RECEPTOR GENE | SPINAL-CORD-INJURY | UNDERLYING NEUROPATHIC PAIN | ALTERED CHLORIDE HOMEOSTASIS | NERVE INJURY | NEUROSCIENCES | INDUCED ABNORMAL PAIN | Brain-Derived Neurotrophic Factor - genetics | Biophysical Phenomena - drug effects | Motor Activity - drug effects | Male | Ribosome Inactivating Proteins, Type 1 - pharmacology | Touch | CD11b Antigen - genetics | Microglia - physiology | Time Factors | Chlorides - metabolism | Pain Threshold - drug effects | Biophysical Phenomena - genetics | Vocalization, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Homeostasis - drug effects | Protein Synthesis Inhibitors - pharmacology | Spinal Cord - cytology | Neurons - drug effects | Membrane Potentials - drug effects | Hot Temperature - adverse effects | Microglia - drug effects | Mice, Inbred C57BL | Rats | Mice, Transgenic | Signal Transduction - genetics | Down-Regulation - drug effects | Rats, Sprague-Dawley | Symporters - metabolism | Gene Expression Regulation - drug effects | Narcotics - administration & dosage | Patch-Clamp Techniques | Rotarod Performance Test | Animals | Hyperalgesia - drug therapy | Signal Transduction - drug effects | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Mice | CD11b Antigen - metabolism | Receptors, Purinergic P2X4 - metabolism | Morphine - administration & dosage | Receptors, Purinergic P2X4 - genetics | Ion Channel Gating - drug effects
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 03/2014, Volume 37, Issue 3, pp. 589 - 600
Salt sensitive (pea) and salt tolerant (barley) species were used to understand the physiological basis of differential salinity tolerance in crops. Pea plants... 
potassium homeostasis | H+‐ATPase | ion channels | membrane depolarization | H | Ion channels | Membrane depolarization | Potassium homeostasis | ATPase | H+-ATPASE ACTIVITY | LIPID-PEROXIDATION | ION-TRANSPORT | K+/NA+ HOMEOSTASIS | POTASSIUM-TRANSPORT | SALT TOLERANCE | PLANT SCIENCES | HYDROXYL RADICALS | H+-ATPase | HYDROGEN-PEROXIDE | ROOT PLASMA-MEMBRANE | NA+ TRANSPORT | Organ Specificity - drug effects | Potassium - metabolism | Plant Shoots - growth & development | Gadolinium - pharmacology | Xylem - physiology | Reactive Oxygen Species - pharmacology | Xylem - drug effects | Biomass | Sodium - metabolism | Plant Roots - drug effects | Salt-Tolerance - drug effects | Plant Roots - physiology | Potassium Channels - metabolism | Adenosine Triphosphate - metabolism | Membrane Transport Modulators - pharmacology | Plant Shoots - drug effects | Stress, Physiological - drug effects | Membrane Potentials - drug effects | Plant Epidermis - physiology | Hordeum - drug effects | Permeability - drug effects | Peas - physiology | Peas - growth & development | Peas - drug effects | Plant Epidermis - drug effects | Hydrogen Peroxide - metabolism | Salinity | Hordeum - physiology | Hordeum - growth & development | Kinetics | Barley | Peas | Energy conservation | Physiological aspects | Plants | Adenosine triphosphatase
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 9, pp. 3953 - 3966
Down syndrome (DS) is associated with neurological complications, including cognitive deficits that lead to impairment in intellectual functioning. Increased... 
Protein Binding - genetics | Electric Stimulation | Cell Count | Male | GABA Modulators - therapeutic use | Learning Disorders - etiology | Hyperkinesis - drug therapy | Neurogenesis - genetics | Long-Term Potentiation - drug effects | Protein Binding - drug effects | Exploratory Behavior - drug effects | Reflex, Startle - drug effects | Imidazoles - therapeutic use | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Mice, Transgenic | Hippocampus - pathology | Imidazoles - pharmacology | Psychomotor Performance - drug effects | Hyperkinesis - etiology | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Analysis of Variance | Seizures - etiology | Glutamate Decarboxylase - metabolism | Mice | Receptors, GABA-A - metabolism | Benzodiazepines - therapeutic use | Tritium - pharmacokinetics | Sensory Gating - drug effects | Reflex - genetics | Reflex - drug effects | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Ki-67 Antigen | Reaction Time - drug effects | GABA Modulators - pharmacology | Neurons - physiology | Down Syndrome - complications | Membrane Proteins - metabolism | Neurogenesis - drug effects | Neurons - drug effects | Cues | Down Syndrome - pathology | Benzodiazepines - pharmacology | Acoustic Stimulation | Mice, Inbred C57BL | Learning Disorders - drug therapy | Long-Term Potentiation - genetics | Biophysics | Maze Learning - drug effects | Rotarod Performance Test | Animals | Carrier Proteins - metabolism | Down Syndrome - drug therapy | Cell Proliferation - drug effects
Journal Article
Neuron, ISSN 0896-6273, 2011, Volume 70, Issue 3, pp. 482 - 494
Transient receptor potential melastatin-3 (TRPM3) is a broadly expressed Ca -permeable nonselective cation channel. Previous work has demonstrated robust... 
TEMPERATURE | TRPV4 | CATION CHANNEL | ION-CHANNEL | PREGNENOLONE SULFATE | VANILLOID RECEPTOR-1 | COLD | CAPSAICIN-RECEPTOR | NEUROSCIENCES | MICE LACKING | EVOKED ACTIVATION | Hyperalgesia - chemically induced | Telemetry - methods | Calcium - metabolism | Capsaicin - pharmacology | Humans | Ganglia, Spinal - cytology | Transient Receptor Potential Channels - deficiency | Inflammation - metabolism | Time Factors | Behavior, Animal - drug effects | Sensory Receptor Cells - metabolism | Disease Models, Animal | Membrane Potentials - drug effects | Plant Oils - pharmacology | Trigeminal Ganglion - cytology | Mice, Knockout | Blood Glucose - drug effects | Patch-Clamp Techniques | Hyperalgesia - genetics | Transient Receptor Potential Channels - genetics | Gene Expression Regulation - radiation effects | TRPM Cation Channels - genetics | Blood Glucose - genetics | Mice | Inflammation - chemically induced | Mustard Plant | Pain Threshold - physiology | TRPM Cation Channels - deficiency | Membrane Potentials - genetics | Pregnenolone - adverse effects | Dose-Response Relationship, Drug | Transfection - methods | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Freund's Adjuvant - adverse effects | Pain Threshold - drug effects | Nifedipine - pharmacology | Hot Temperature - adverse effects | Hyperalgesia - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Pain Measurement - drug effects | Calcium Channel Blockers - pharmacology | Pain Measurement - methods | Animals | Sensory Receptor Cells - drug effects | TRPM Cation Channels - antagonists & inhibitors | Hyperalgesia - drug therapy | TRPA1 Cation Channel | Inflammation - genetics | Acrylamides - therapeutic use | TRPM Cation Channels - metabolism | Cell Line, Transformed | Chemotherapy | Progesterone | Sulfates | Cancer | Heat | Behavior | Cold | Neurons | Rodents
Journal Article
Neuron, ISSN 0896-6273, 2004, Volume 43, Issue 5, pp. 729 - 743
Journal Article
Neuron, ISSN 0896-6273, 12/2015, Volume 88, Issue 5, pp. 957 - 972
Adult neurogenesis is regulated by the neurogenic niche, through mechanisms that remain poorly defined. Here, we investigated whether niche-constituting... 
D-SERINE | NMDA RECEPTORS | CNS SYNAPTOGENESIS | NEWLY GENERATED NEURONS | CRITICAL PERIOD | NEUROGENESIS | RELEASE | DENTATE GYRUS | GRANULE CELLS | GLIA | NEUROSCIENCES | Glial Fibrillary Acidic Protein - genetics | Synaptic Transmission - genetics | SNARE Proteins - genetics | Sodium Chloride - pharmacology | Receptors, N-Methyl-D-Aspartate - metabolism | Phosphopyruvate Hydratase - metabolism | Synapses - genetics | Glial Fibrillary Acidic Protein - metabolism | Excitatory Postsynaptic Potentials - drug effects | Clostridium botulinum type B - genetics | Receptors, N-Methyl-D-Aspartate - genetics | Neurogenesis - genetics | Neurons - ultrastructure | Neurons - physiology | Synaptic Transmission - drug effects | Clostridium botulinum type B - metabolism | Excitatory Postsynaptic Potentials - genetics | Membrane Potentials - drug effects | Synapses - physiology | Dendritic Spines - physiology | Mice, Transgenic | Synapses - ultrastructure | Excitatory Amino Acid Transporter 1 - metabolism | Hippocampus - cytology | Membrane Potentials - physiology | Astrocytes - ultrastructure | Astrocytes - physiology | Animals | Neurogenesis - physiology | Serine - pharmacology | Tamoxifen - pharmacology | Mice | SNARE Proteins - metabolism | Dendritic Spines - ultrastructure | Neurosciences | Genetic engineering | Neurons | Analysis | Studies | Hypothesis testing | Rodents | Stem cells | Variance analysis | Neurogenesis
Journal Article
Neuron, ISSN 0896-6273, 2009, Volume 63, Issue 1, pp. 27 - 39
Journal Article
Nature Neuroscience, ISSN 1097-6256, 03/2012, Volume 15, Issue 3, pp. 477 - 486
Efforts to study the development and function of the human cerebral cortex in health and disease have been limited by the availability of model systems.... 
SUBTYPE | HUMAN ES | EVOLUTION | NEOCORTICAL NEURONOGENESIS | NEURONS | NEUROGENESIS | SUBVENTRICULAR ZONE | SPECIFICATION | DIFFERENTIATION | MODEL | NEUROSCIENCES | Disks Large Homolog 4 Protein | Embryonic Stem Cells - cytology | Humans | Synaptic Potentials - drug effects | Ki-67 Antigen - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Cerebral Cortex - cytology | Piperidines - pharmacology | Time Factors | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Fetus | Membrane Proteins - metabolism | Tetrodotoxin - pharmacology | Cell Differentiation - physiology | Potassium Channel Blockers - pharmacology | Cell Line | Synapses - drug effects | Synaptic Potentials - physiology | Pluripotent Stem Cells - cytology | Glutamic Acid - pharmacology | Synapses - physiology | Pluripotent Stem Cells - physiology | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Embryonic Stem Cells - physiology | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Patch-Clamp Techniques | Cerebral Cortex - embryology | Signal Transduction - drug effects | Cell Differentiation - drug effects | Neurogenesis - physiology | Pluripotent Stem Cells - drug effects | RNA, Messenger | Retinoids - pharmacology | Physiological aspects | Cerebral cortex | Research | Synapses | Stem cells
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2010, Volume 16, Issue 11, pp. 1299 - 1304
Bitter taste receptors (TAS2Rs) on the tongue probably evolved to evoke signals for avoiding ingestion of plant toxins. We found expression of TAS2Rs on human... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | CONTRACTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXATION | CELL BIOLOGY | HETEROGENEITY | LACTONES | ASTHMA | CHANNELS | MAMMALIAN TASTE | EXPRESSION | SPARKS | Asthma - metabolism | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Bronchi - physiopathology | Myocytes, Smooth Muscle - pathology | RNA, Messenger - metabolism | Airway Obstruction - metabolism | Bronchi - drug effects | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Muscle Relaxation - physiology | Bronchoconstriction - drug effects | Bronchi - metabolism | Bronchi - pathology | Myocytes, Smooth Muscle - metabolism | Membrane Potentials - drug effects | Bronchoconstriction - physiology | Asthma - physiopathology | Cell Separation | RNA, Messenger - genetics | Airway Obstruction - physiopathology | Muscle, Smooth - metabolism | Membrane Potentials - physiology | Taste - physiology | Gene Expression Regulation - drug effects | Animals | Taste - drug effects | Asthma - complications | Calcium Signaling - drug effects | Airway Obstruction - pathology | Muscle, Smooth - physiopathology | Mice | Receptors, G-Protein-Coupled - genetics | Muscle Relaxation - drug effects | Muscle, Smooth - pathology | Saccharin - pharmacology | Taste buds | Care and treatment | Usage | Animal models in research | Physiological aspects | Smooth muscle | Genetic aspects | Airway obstruction (Medicine) | Research | Risk factors | Signal transduction | Taste | Calcium | Cellular biology | Respiratory diseases
Journal Article
Journal Article