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Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 201 - 206
The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly,... 
PATHOGENESIS | LOCALIZES | COMPLEX | PROTEIN | BECLIN-1 | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | BINDING | Apoptosis Regulatory Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Humans | Cell Membrane Permeability | Molecular Sequence Data | Peptide Fragments - pharmacology | Membrane Proteins - pharmacology | Membrane Proteins - therapeutic use | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Beclin-1 | Amino Acid Sequence | HIV-1 - metabolism | Virus Replication - drug effects | Peptide Fragments - metabolism | HIV-1 - drug effects | tat Gene Products, Human Immunodeficiency Virus - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | West Nile virus - drug effects | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Chikungunya virus - drug effects | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Mice | HeLa Cells | Apoptosis Regulatory Proteins - therapeutic use | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Peptides | Microscopy | Rodents | Mortality | Amino acids | Infections | Autophagy
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2007, Volume 104, Issue 21, pp. 8947 - 8952
The use of recombinant tumor antigen proteins is a realistic approach for the development of generic cancer vaccines, but the potential of this type of... 
T lymphocytes | Cancer vaccines | Antigens | Cross priming | B lymphocytes | Plasmids | Vaccination | Melanoma | Antibodies | Tumors | Cancer vaccine | PLASMACYTOID DENDRITIC CELLS | B-CELLS | IMMUNIZATION | CANCER-PATIENTS | EPITOPE | cancer vaccine | CANCER/TESTIS ANTIGENS | IMMUNE-RESPONSES | DNA | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | TUMOR-ANTIGEN | Recombinant Proteins - therapeutic use | Mannitol - blood | Humans | Membrane Proteins - adverse effects | Epitopes, B-Lymphocyte - immunology | Membrane Proteins - therapeutic use | Recombinant Proteins - adverse effects | Th1 Cells - immunology | Oleic Acids - blood | Oligodeoxyribonucleotides - blood | Antigens, Neoplasm - therapeutic use | Antigens, Neoplasm - blood | Antibodies - immunology | Oligodeoxyribonucleotides - adverse effects | Antigens, Neoplasm - adverse effects | Oleic Acids - adverse effects | Membrane Proteins - blood | Oligodeoxyribonucleotides - therapeutic use | Mannitol - adverse effects | Oligodeoxyribonucleotides - immunology | Antigens, Neoplasm - immunology | Oleic Acids - therapeutic use | Mannitol - therapeutic use | Membrane Proteins - immunology | Immunotherapy - adverse effects | Mannitol - analogs & derivatives | Neoplasms - drug therapy | Recombinant Proteins - blood | Cancer Vaccines - immunology | Cross-Priming - immunology | Recombinant Proteins - immunology | Mannitol - immunology | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Oleic Acids - immunology | Research | T cells | Tumor antigens | Biological Sciences
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2017, Volume 245, pp. 81 - 94
Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent... 
Peptide vaccine | Tumor microenvironment | Sunitinib base | Advanced melanoma | Polymeric micelles | CANCER-IMMUNOTHERAPY | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | NANOPARTICLES | CO-DELIVERY | CISPLATIN | IMMUNE SUPPRESSION | GROWTH | CELL CARCINOMA PATIENTS | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Oligodeoxyribonucleotides - administration & dosage | Calcium Phosphates - therapeutic use | Oligodeoxyribonucleotides - chemistry | Immunotherapy, Active | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Membrane Proteins - therapeutic use | Indoles - administration & dosage | Polymers - therapeutic use | Cancer Vaccines - therapeutic use | Pyrroles - administration & dosage | Micelles | Female | Proto-Oncogene Proteins c-akt - metabolism | Pyrroles - therapeutic use | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Oligodeoxyribonucleotides - therapeutic use | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Calcium Phosphates - chemistry | Melanoma - pathology | Antineoplastic Agents - chemistry | Membrane Proteins - administration & dosage | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Tumor Burden - drug effects | Melanoma - immunology | Calcium Phosphates - administration & dosage | Cell Line, Tumor | Pyrroles - chemistry | Indoles - therapeutic use | Polymers - chemistry | Peptide Fragments - therapeutic use | Melanoma - therapy | Indoles - chemistry | Tyrosine | Care and treatment | Analysis | Immunotherapy | Melanoma | Calcium phosphate | Vaccines | T cells | Tumors | Cancer | Advanced Melanoma
Journal Article