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Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7656, pp. 107 - 112
Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal antibody that targets the beta-subunit of the pituitary hormone... 
WHITE | OBESITY | ENERGY-EXPENDITURE | BROWN-FAT | OSTEOCLAST FORMATION | MULTIDISCIPLINARY SCIENCES | FOLLICLE-STIMULATING-HORMONE | RECEPTOR | BONE MASS | MENOPAUSAL TRANSITION | OVARIECTOMIZED MICE | Obesity - drug therapy | Receptors, FSH - genetics | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Follicle Stimulating Hormone, beta Subunit - antagonists & inhibitors | Male | Osteoporosis - drug therapy | Adipocytes - drug effects | Uncoupling Protein 1 - biosynthesis | Adipose Tissue - metabolism | Antibodies - immunology | Female | Receptors, FSH - metabolism | Adiposity - drug effects | Ovariectomy | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, FSH - antagonists & inhibitors | Haploinsufficiency | Antibodies - pharmacology | Animals | Oxygen Consumption - drug effects | Adipocytes - metabolism | Obesity - prevention & control | Follicle Stimulating Hormone, beta Subunit - immunology | Adipose Tissue, Beige - drug effects | Mice | Thermogenesis - drug effects | Adipose Tissue - drug effects | Adipose Tissue, Beige - metabolism | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Physiological research | Follicle-stimulating hormone | Thermogenesis | Research | Adipose tissue | Body fat | Menopause | Adipocytes | Hormones | Density | Osteoporosis | Mitochondria | Biomedical materials | Biocompatibility | Bone loss | Adipose tissue (brown) | Binding | Obesity | Immunoglobulins | Pituitary hormones | Blocking | Metabolism | Bone mass | Pituitary | Bone
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2016, Volume 22, Issue 10, pp. 1160 - 1169
Orthopedic implants containing biodegradable magnesium have been used for fracture repair with considerable efficacy; however, the underlying mechanisms by... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE-RELATED PEPTIDE | VIVO | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNERVATION | OSTEOPOROSIS | CELL BIOLOGY | IN-VITRO | TRAUMATIC BRAIN-INJURY | ALLOYS | DIFFERENTIATION | OSTEOARTHRITIS | EXPRESSION | Bone Nails | Humans | Fracture Fixation, Intramedullary | Ganglia, Spinal - cytology | Cyclic AMP Response Element-Binding Protein - drug effects | Gene Knockdown Techniques | Transcription Factors - drug effects | Stem Cells | Fracture Healing - drug effects | Osteoporosis, Postmenopausal | Cation Transport Proteins - metabolism | Female | Neurons - metabolism | Calcitonin Gene-Related Peptide - metabolism | Neurons - drug effects | Osteogenesis - genetics | Osteoporotic Fractures | Calcitonin Gene-Related Peptide - drug effects | Ovariectomy | Calcitonin Gene-Related Peptide - pharmacology | Osteogenesis - drug effects | Capsaicin - toxicity | Femoral Fractures | Rats | Femur - drug effects | Sensory System Agents - toxicity | Receptor Activity-Modifying Protein 1 - genetics | Magnesium - pharmacology | Gene Knock-In Techniques | Periosteum - cytology | Transcription Factors - metabolism | Animals | Cell Differentiation - drug effects | Calcitonin Receptor-Like Protein - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | TRPM Cation Channels - metabolism | Fracture Healing - genetics | Denervation | Neuropeptides | Fracture fixation | Genetic aspects | Wound healing | Health aspects | Surgical implants | Femur | Transplants & implants | Biodegradability | Capsaicin | Genes | Menopause | Differentiation (biology) | Stem cell transplantation | Cortex (somatosensory) | Receptor activity modifying proteins | Proteins | Osteoporosis | Biomedical materials | Bone growth | Allografts | Dorsal root ganglia | Surgery | Calcitonin | Nerves | Sensory neurons | Biocompatibility | Ion channels | Magnesium | Bone (cortical) | Repair | Adenosine triphosphate | Biodegradation | Periosteum | Implantation | Bone healing | Ganglia | Calcitonin gene-related peptide | Bone implants | Fractures | Orthopedics | Stem cells | Healing | Bone | ATP | Transporter | Osteogenesis
Journal Article
Endocrinology, ISSN 0013-7227, 07/2015, Volume 156, Issue 7, pp. 2632 - 2645
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2014, Volume 370, Issue 5, pp. 412 - 420
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 09/2011, Volume 26, Issue 9, pp. 2096 - 2111
Journal Article
Frontiers in Neuroendocrinology, ISSN 0091-3022, 2010, Volume 31, Issue 4, pp. 400 - 419
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2017, Volume 377, Issue 15, pp. 1417 - 1427
Among postmenopausal women with osteoporosis and a high risk of fracture, treatment with the monoclonal antibody romosozumab for 12 months followed by... 
MEDICINE, GENERAL & INTERNAL | METAANALYSIS | BONE-MINERAL DENSITY | VERTEBRAL FRACTURES | DISEASE | AORTA | RANDOMIZED-TRIAL | RISK | STRENGTH | POSTMENOPAUSAL WOMEN | SCLEROSTEOSIS | Humans | Antibodies, Monoclonal - adverse effects | Fractures, Bone - epidemiology | Antibodies, Monoclonal - therapeutic use | Risk | Bone Remodeling - drug effects | Alendronate - therapeutic use | Incidence | Spinal Fractures - prevention & control | Female | Drug Therapy, Combination | Bone Density Conservation Agents - adverse effects | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Spinal Fractures - epidemiology | Bone Density Conservation Agents - therapeutic use | Osteoporosis, Postmenopausal - drug therapy | Bone Density Conservation Agents - pharmacology | Alendronate - adverse effects | Bone Density - drug effects | Alendronate - pharmacology | Least-Squares Analysis | Aged | Cardiovascular Diseases - chemically induced | Fractures, Bone - prevention & control | Treatment outcome | Care and treatment | Fractures | Growth | Analysis | Monoclonal antibodies | Bones | Research | Jaw | Femur | Vertebrae | Immunoglobulins | Inhibitor drugs | Osteonecrosis | SOST protein | Bisphosphonates | Hip | Post-menopause | Bone resorption | Osteoporosis | Alendronic acid | Bone growth | Bone density | Drug therapy | Osteogenesis | randomized-trial | metaanalysis | disease | postmenopausal women | strength | bone-mineral density | Klinisk medicin | vertebral fractures | sclerosteosis | Clinical Medicine | aorta | risk | General & Internal Medicine
Journal Article