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1. Full Text Lukas Hintermann
European journal of organic chemistry, ISSN 1434-193X, 10/2017, Volume 2017, Issue 37, pp. 5423 - 5423
Menthol
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2. Full Text Menthol: A simple monoterpene with remarkable biological properties
by Kamatou, Guy P.P and Vermaak, Ilze and Viljoen, Alvaro M and Lawrence, Brian M
Phytochemistry (Oxford), ISSN 0031-9422, 12/2013, Volume 96, pp. 15 - 25
Cooling effects | Mentha piperita | Menthol | Flavour | Mentha canadensis | Biological activity | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Monoterpenes - isolation & purification | Oils, Volatile - chemistry | Humans | Oils, Volatile - pharmacology | Menthol - chemistry | Oils, Volatile - isolation & purification | Body Temperature - physiology | Mentha - chemistry | Monoterpenes - pharmacology | Menthol - isolation & purification | Menthol - pharmacology | Monoterpenes - chemistry | Molecular Structure | Index Medicus
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3. Full Text TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
by Liu, Boyi and Fan, Lu and Balakrishna, Shrilatha and Sui, Aiwei and Morris, John B and Jordt, Sven-Eric
Pain (Amsterdam), ISSN 0304-3959, 10/2013, Volume 154, Issue 10, pp. 2169 - 2177
Analgesia | Acrolein | Heat | Visceral pain | TRPA1 | Capsaicin | Menthol | TRPM8 | TRPV1 | Acetic acid | Inflammatory pain | Menthol Analgesia TRPM8 TRPV1 TRPA1 Inflammatory pain Visceral pain Acetic acid Acrolein Capsaicin Heat | Neurosciences | Clinical Neurology | Anesthesiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors | Acute Pain - drug therapy | Analgesia - methods | Mice, Inbred C57BL | Cells, Cultured | Male | Pain Measurement - drug effects | TRPM Cation Channels - physiology | Mice, Knockout | Pain Measurement - methods | Animals | Menthol - pharmacology | Menthol - therapeutic use | Acute Pain - physiopathology | Inflammation - drug therapy | Mice | Inflammation - physiopathology | Analgesics | Index Medicus
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4. Menthol - pharmacology of an important naturally medicinal "cool"
by Farco, Joseph A and Grundmann, Oliver
Mini reviews in medicinal chemistry, ISSN 1389-5575, 2013, Volume 13, Issue 1, pp. 124 - 131
Menthol | TRPM8 | TRPA1 | CMR1 | Mentha x piperita | Nicotine | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological Products - chemistry | Animals | Menthol - pharmacology | Menthol - therapeutic use | Humans | Menthol - adverse effects | Biological Products - adverse effects | Biological Products - pharmacology | Menthol - chemistry | Transient Receptor Potential Channels - metabolism | Transient Receptor Potential Channels - agonists | Biological Products - therapeutic use | Index Medicus
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5. Full Text Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations
by Narayan, Alison R. H and Jiménez-Osés, Gonzalo and Liu, Peng and Negretti, Solymar and Zhao, Wanxiang and Gilbert, Michael M and Ramabhadran, Raghunath O and Yang, Yun-Fang and Furan, Lawrence R and Li, Zhe and Podust, Larissa M and Montgomery, John and Houk, K.N and Sherman, David H
Nature chemistry, ISSN 1755-4330, 08/2015, Volume 7, Issue 8, pp. 653 - 660
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Hydroxylation | Oxidation-Reduction | Stereoisomerism | Cytochrome P-450 Enzyme System - metabolism | Substrate Specificity | Menthol - chemistry | Molecular Dynamics Simulation | Cytochrome P-450 Enzyme System - chemistry | Menthol - analogs & derivatives | Quantum Theory | Streptomyces - enzymology | Catalysis | Menthol - metabolism | Protein engineering | Computer simulation | Molecular dynamics | Selectivity | Monooxygenase | Substrates | Methylene | Stereoselectivity | Hydrogen bonds | Prediction models | Quantum mechanics | Chemical bonds | Metabolic pathways | Menthol | Oxidation | Index Medicus
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6. Full Text Combination with l-Menthol Enhances Transdermal Penetration of Indomethacin Solid Nanoparticles
by Nagai, Noriaki and Ogata, Fumihiko and Yamaguchi, Mizuki and Fukuoka, Yuya and Otake, Hiroko and Nakazawa, Yosuke and Kawasaki, Naohito
International journal of molecular sciences, ISSN 1422-0067, 08/2019, Volume 20, Issue 15, p. 3644
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Nanoparticles - chemistry | Rats | Skin Absorption | Menthol - chemistry | Menthol - pharmacokinetics | Administration, Cutaneous | Indomethacin - administration & dosage | Drug Carriers - chemistry | Drug Delivery Systems | Indomethacin - pharmacokinetics | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Drug Compounding | Indomethacin - chemistry | Microscopy, Atomic Force | Menthol - administration & dosage | Spectrum Analysis | Drug Combinations | Drugs | Particle size | Drug delivery systems | L-Menthol | Inflammation | Permeability | Transdermal medication | Cosmetics industry | Nanoparticles | Studies | Penetration | Zeta potential | Skin | Menthol | Indomethacin | Index Medicus | skin | nanoparticle | drug delivery | l-menthol | indomethacin
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7. Full Text Molecular Interaction between Intercellular Lipids in the Stratum Corneum and l-Menthol, as Analyzed by Synchrotron X-Ray Diffraction
by Yoshida, Shinya and Obata, Yasuko and Onuki, Yoshinori and Utsumi, Shunichi and Ohta, Noboru and Takahashi, Hiroshi and Takayama, Kozo and Graduate School of Engineering and Gunma University and cJapan Synchrotron Radiation Research Institute (SPring-/JASRI and Hoshi University and University of Toyama and bDepartment of Pharmaceutical Technology and Graduate School of Medical and Pharmaceutical Science and aDepartment of Pharmaceutics and dDepartment of Chemistry and Chemical Biology
Chemical & pharmaceutical bulletin, ISSN 0009-2363, 2017, Volume 65, Issue 2, pp. 134 - 142
synchrotron X-ray diffraction | intercellular lipid | stratum corneum | lipid model | vaporized l-menthol | Lipid model | Vaporized l-menthol | Stratum corneum | Synchrotron X-ray diffraction | Intercellular lipid | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Skin - metabolism | Mice, Hairless | Ceramides - chemistry | Menthol - chemistry | Cholesterol - chemistry | Animals | Models, Biological | Synchrotrons | X-Ray Diffraction | Mice | Menthol - metabolism | Palmitic Acid - chemistry | Menthol - analysis | Drugs | Infrared spectroscopy | Fourier transforms | L-Menthol | X-ray diffraction | Lipids | Palmitic acid | Lipid structure | Transdermal medication | Lamellar structure | Packing | Fluidity | Temperature effects | Menthol | Differential scanning calorimetry | Solvents | Molecular interactions | Permeation | Crystallization | Cholesterol | Diffraction | Calorimetry | Skin | Models | Index Medicus
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8. Full Text Oral l-menthol reduces thermal sensation, increases work-rate and extends time to exhaustion, in the heat at a fixed rating of perceived exertion
by Flood, T.R and Waldron, M and Jeffries, O
European journal of applied physiology, ISSN 1439-6319, 07/2017, Volume 117, Issue 7, pp. 1501 - 1512
Thermoregulation | Pacing | Perception | Heat | Menthol | Exercise | Physiology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Mouthwashes | Menthol - pharmacology | Energy Metabolism | Humans | Adult | Male | Hot Temperature | Physical Exertion - drug effects | Menthol - administration & dosage | Perception - drug effects | Skin Temperature | Heart rate | Physical training | Cold | Temperature effects | L-Menthol | Human factors research | Skin | Index Medicus
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9. Full Text Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
by Yin, Ying and Le, Son C and Hsu, Allen L and Borgnia, Mario J and Yang, Huanghe and Lee, Seok-Yong
Science (American Association for the Advancement of Science), ISSN 0036-8075, 2019, Volume 363, Issue 6430, p. 945
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein Structure, Tertiary | Cold Temperature | TRPM Cation Channels - chemistry | Models, Molecular | Menthol - chemistry | Calcium - chemistry | Membrane Lipids - chemistry | Pyrimidinones - chemistry | Cryoelectron Microscopy | Menthol - analogs & derivatives | Animals | Songbirds - physiology | Binding Sites | Phosphatidylinositol 4,5-Diphosphate - chemistry | Biological research | Coolant | Molecular structure | Ion channels | Biophysics | Research | Properties | Biology, Experimental | Structural design | Interlayers | Calcium | Coupling agents | Capsaicin receptors | Lipids | Activation | Phosphatidylinositol 4,5-diphosphate | Coupling (molecular) | Transient receptor potential proteins | Allosteric properties | Dependence | Menthol | Channel opening | Cooling | Calcium (intracellular) | Cold | Channel gating | Structural engineering | Permeability | Electron microscopy | Calcium permeability | Organic chemistry | Microscopy | Supercooling | Ligands | Intracellular | Detection | Binding sites | Recognition | Calcium ions | Conformation | Structure-function relationships
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