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Free Radical Biology and Medicine, ISSN 0891-5849, 12/2015, Volume 89, pp. 873 - 882
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 10/2019, Volume 473, pp. 112636 - 112636
Macrophages are a diverse population of cells originating from the myeloid lineage, which form an important component of the innate immune system, helping to... 
Efferocytosis | CD14 | MerTK | High content imaging | Multiparametric | Macrophage | Index Medicus
Journal Article
Journal Article
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 07/2019, Volume 115, Issue 8, pp. 1286 - 1295
The TAM receptors are a distinct family of three receptor tyrosine kinases, namely Tyro3, Axl, and MerTK. Since their discovery in the early 1990s, they have... 
NATURAL-KILLER-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | DENDRITIC CELLS | Tyro3 | Cardiovascular disease | PHOSPHATE-INDUCED CALCIFICATION | VASCULAR SMOOTH-MUSCLE | TAM receptors | Axl | MERTK RECEPTOR | TYROSINE KINASE RECEPTOR | APOPTOTIC CELL ACCUMULATION | PROTEIN-S | INFLAMMATORY RESPONSE | MerTK | ARREST-SPECIFIC GENE | Invited Reviews | Editor's Choice
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2669 - 2683
Tyro3, Axl, and Mertk (TAM) represent a family of homologous tyrosine kinase receptors known for their functional role in phosphatidylserine (PS)-dependent... 
MERTK INHIBITION | SIGNALING PATHWAYS | ONCOLOGY | GROWTH | EFFEROCYTOSIS | PROTEIN-S | PHOSPHATIDYLSERINE | EXPRESSION | SMALL-MOLECULE INHIBITION | AXL KINASE | FAMILY
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 07/2019, Volume 6, Issue 4, pp. 1611161 - 1611161
Canonically the oncogenic kinase AKT is activated by growth signals. Our work suggests apoptotic materials, abundant in tumors, also contribute to AKT... 
drug resistance | Akt | MERTK | Kidney cancer | SAV1
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 12/2016, Volume 7, Issue 12, pp. 1044 - 1049
Mer tyrosine kinase (MerTK) is aberrantly elevated in various tumor cells and has a normal anti-inflammatory role in the innate immune system. Inhibition of... 
structure-based drug design | macrocycle | MerTK inhibitors | MerTK | pyrrolopyrimidine | TAM kinase | APOPTOTIC THYMOCYTES | CLEARANCE | TAM FAMILY | MIMICRY | CHEMISTRY, MEDICINAL | MACROPHAGES | DRUG DISCOVERY | VACCINIA VIRUS | POTENT | C-MER | MACROPINOCYTOSIS
Journal Article
Journal Article
Neurology: Neuroimmunology & Neuroinflammation, ISSN 2332-7812, 11/2017, Volume 4, Issue 6, p. e408
Journal Article
Journal Article
Blood, ISSN 0006-4971, 05/2019, Volume 134, Issue 5, pp. 480 - 491
The erythroblastic island (EBI), composed of a central macrophage and surrounding erythroid cells, was the first hematopoietic niche discovered. The identity... 
POLYCYTHEMIA-VERA | STROMAL MACROPHAGES | INEFFECTIVE ERYTHROPOIESIS | BONE-MARROW | MERTK-MEDIATED ENGULFMENT | CELL-ADHESION | FUNCTIONAL-CHARACTERIZATION | BETA-THALASSEMIA | HEMATOLOGY | QUANTITATIVE-ANALYSIS | ERYTHROID PROGENITORS | Index Medicus | Abridged Index Medicus
Journal Article