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1. Full Text Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria
by Boyle, Michelle J and Reiling, Linda and Feng, Gaoqian and Langer, Christine and Osier, Faith H and Aspeling-Jones, Harvey and Cheng, Yik Sheng and Stubbs, Janine and Tetteh, Kevin K.A and Conway, David J and McCarthy, James S and Muller, Ivo and Marsh, Kevin and Anders, Robin F and Beeson, James G
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 580 - 590
Antibodies play major roles in immunity to malaria; however, a limited understanding of mechanisms mediating protection is a major barrier to vaccine... 
IMMUNITY | RESPONSES | GROWTH-INHIBITION | PARASITEMIA | SPECIFICITY | VACCINE | FRAGMENT | IMMUNOLOGY | BLOOD-STAGE ANTIGENS | IMMUNOGLOBULIN-G | CHILDREN | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Prospective Studies | Protozoan Proteins - antagonists & inhibitors | Humans | Merozoite Surface Protein 1 - genetics | Child, Preschool | Complement Fixation Tests | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Complement C1q - metabolism | Immunoglobulin G - biosynthesis | Malaria Vaccines - immunology | Female | Antigens, Protozoan - genetics | Merozoite Surface Protein 1 - antagonists & inhibitors | Child | Complement Pathway, Classical | Erythrocytes - immunology | Merozoites - immunology | Gene Expression | Parasitemia - immunology | Antibodies, Protozoan - biosynthesis | Host-Pathogen Interactions | Malaria, Falciparum - parasitology | Animals | Malaria Vaccines - administration & dosage | Merozoite Surface Protein 1 - immunology | Adolescent | Malaria, Falciparum - immunology | Parasitemia - prevention & control | Parasitemia - parasitology | Erythrocytes - parasitology | Protozoan Proteins - immunology | Proteins | Viral antibodies | Antibodies | Plasmodium falciparum | Malaria | Survival analysis | Parasites | Microscopy | Blood banks
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2. Full Text A library of functional recombinant cell-surface and secreted p. Falciparum merozoite proteins
by Crosnier, Cécile and Wanaguru, Madushi and McDade, Brian and Osier, Faith H and Marsh, Kevin and Rayner, Julian C and Wright, Gavin J
Molecular and Cellular Proteomics, ISSN 1535-9476, 12/2013, Volume 12, Issue 12, pp. 3976 - 3986
Malaria, an infectious disease caused by parasites of the Plasmodium genus, is one of the world's major public health concerns causing up to a million deaths... 
HIGH-LEVEL | ENHANCED EXPRESSION | RTS,S/AS01 MALARIA VACCINE | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | PARASITE PLASMODIUM-FALCIPARUM | MULTIGENE FAMILY | PHASE-3 TRIAL | INHIBITORY ANTIBODIES | HETEROLOGOUS EXPRESSION | ERYTHROCYTE INVASION | Proteome - genetics | Antigens, Protozoan - immunology | Immune Sera - chemistry | Humans | Merozoite Surface Protein 1 - genetics | Peptide Library | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Proteome - immunology | Cloning, Molecular | HEK293 Cells | Antigens, Surface - metabolism | Plasmodium falciparum - metabolism | Antigens, Protozoan - genetics | Membrane Proteins - metabolism | Carrier Proteins - immunology | Merozoites - metabolism | Merozoites - immunology | Recombinant Proteins - metabolism | Gene Expression | Membrane Proteins - genetics | Molecular Sequence Annotation | Antigens, Surface - genetics | Sialic Acids - metabolism | Membrane Proteins - immunology | Recombinant Proteins - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Protein Binding | Erythrocytes - parasitology | Merozoites - chemistry | Antigens, Surface - immunology | Proteome - metabolism | Protozoan Proteins - immunology | Technological Innovation and Resources
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3. Full Text Merozoite surface protein 1 from plasmodium falciparum is a major target of opsonizing antibodies in individuals with acquired immunity against malaria
by Jäschke, Anja and Coulibaly, Boubacar and Remarque, Edmond J and Bujard, Hermann and Epp, Christian
Clinical and Vaccine Immunology, ISSN 1556-6811, 11/2017, Volume 24, Issue 11
Naturally acquired immunity against malaria is largely mediated by serum antibodies controlling levels of blood-stage parasites. A limited understanding of the... 
Opsonizing antibodies | Neutrophil | Respiratory burst | P. falciparum MSP-1 | ADRB | INFECTIOUS DISEASES | PROTECTION | respiratory burst | CELL INVASION | VACCINE | MICROBIOLOGY | ANTIGENS | IMMUNOLOGY | neutrophil | ERYTHROCYTE INVASION | INHIBIT PARASITE GROWTH | C-TERMINAL FRAGMENT | DEPENDENT RESPIRATORY BURST | RECOMBINANT | IN-VITRO GROWTH | opsonizing antibodies | Adaptive Immunity | Merozoites - immunology | Antigens, Protozoan - immunology | Opsonin Proteins - immunology | Immunoglobulin G - blood | Neutrophil Activation | Antibodies, Protozoan - immunology | Respiratory Burst | Humans | Neutrophils - immunology | Macaca mulatta | Plasmodium falciparum - immunology | Antibodies, Protozoan - blood | Animals | Merozoite Surface Protein 1 - immunology | Malaria Vaccines - immunology | Malaria, Falciparum - epidemiology | Malaria, Falciparum - immunology | Burkina Faso - epidemiology | Plasmodium falciparum - growth & development | Merozoites - chemistry
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4. Full Text The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria
by HOLDER, A. A
Parasitology, ISSN 0031-1820, 10/2009, Volume 136, Issue 12, pp. 1445 - 1456
Over the last 30 years, evidence has been gathered suggesting that merozoite Surface protein 1 (MSP1) is a target of protective immunity against malaria. In a... 
MSP1 | Malaria | Structure | Antibody | Merozoite | DISULFIDE BONDS | antibody | PLASMODIUM-FALCIPARUM MEROZOITES | merozoite | CRYSTAL-STRUCTURE | CLINICAL MALARIA | MONOCLONAL-ANTIBODY | SERUM ANTIBODIES | malaria | structure | VACCINE CANDIDATE | FINE SPECIFICITY | GHANAIAN CHILDREN | INVASION INHIBITORY ANTIBODIES | PARASITOLOGY | Antibody Specificity | Malaria, Falciparum - prevention & control | Antigens, Protozoan - chemistry | Antigens, Protozoan - immunology | Antibodies, Protozoan - immunology | Humans | Models, Molecular | Plasmodium falciparum - immunology | Malaria Vaccines - chemistry | Malaria, Falciparum - parasitology | Antibodies, Protozoan - blood | Merozoite Surface Protein 1 - chemistry | Animals | Merozoite Surface Protein 1 - immunology | Malaria Vaccines - immunology | Malaria, Falciparum - immunology | Plasmodium falciparum - metabolism
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5. Full Text Naturally acquired antibody responses to plasmodium vivax and plasmodium falciparum Merozoite Surface Protein 1 (MSP1) C-Terminal 19 kDa domains in an area of unstable malaria transmission in Southeast Asia
by Wang, Qinghui and Zhao, Zhenjun and Zhang, Xuexing and Li, Xuelian and Zhu, Min and Li, Peipei and Yang, Zhaoqing and Wang, Ying and Yan, Guiyun and Shang, Hong and Cao, Yaming and Fan, Qi and Cui, Liwang
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0151900
Understanding naturally acquired immunity to infections caused by Plasmodia in different malaria endemicity settings is needed for better vaccine designs and... 
HUMORAL IMMUNE-RESPONSES | VACCINE CANDIDATE | 19-KILODALTON DOMAIN | BURKINA-FASO | REDUCED RISK | CLINICAL MALARIA | MULTIDISCIPLINARY SCIENCES | SERUM ANTIBODIES | ENDEMIC AREA | BLOOD-STAGE ANTIGENS | IGG SUBCLASSES | Malaria, Vivax - transmission | Demography | Molecular Weight | Follow-Up Studies | Humans | Child, Preschool | Infant | Plasmodium falciparum - immunology | Asia, Southeastern - epidemiology | Malaria, Falciparum - blood | Malaria, Falciparum - transmission | Merozoite Surface Protein 1 - chemistry | Malaria, Vivax - blood | Immunoglobulin G - immunology | Child | Protein Structure, Tertiary | Amino Acid Sequence | Acute Disease | Antibody Formation - immunology | Antibodies, Protozoan - immunology | Malaria, Vivax - parasitology | Logistic Models | Plasmodium vivax - immunology | Malaria, Falciparum - parasitology | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Adolescent | Malaria, Falciparum - immunology | Malaria, Vivax - immunology | Plasmodium falciparum | Disease transmission | Malaria | Physiological aspects | Development and progression | Research | Risk factors | Vector-borne diseases | Immunoglobulins | Plasmodia | Immunoglobulin G | Erythrocytes | Antibodies | Infections | Coexistence | Vaccines | Epidemiology | Patients | Immunity | Merozoite surface protein 1 | Proteins | Microscopy | Enzyme-linked immunosorbent assay | Recombinant
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6. Full Text Immunoglobulin G Subclass-Specific Responses against Plasmodium falciparum Merozoite Antigens Are Associated with Control of Parasitemia and Protection from Symptomatic Illness
by Danielle I. Stanisic and Jack S. Richards and Fiona J. McCallum and Pascal Michon and Christopher L. King and Sonja Schoepflin and Paul R. Gilson and Vincent J. Murphy and Robin F. Anders and Ivo Mueller and James G. Beeson
Infection and Immunity, ISSN 0019-9567, 03/2009, Volume 77, Issue 3, pp. 1165 - 1174
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
APICAL MEMBRANE ANTIGEN-1 | C-TERMINAL FRAGMENT | INFECTIOUS DISEASES | IN-VITRO | CLINICAL MALARIA | PCR-RFLP ANALYSIS | INHIBITORY ANTIBODIES | SERUM ANTIBODIES | IMMUNOLOGY | ANTIBODY-RESPONSE | PAPUA-NEW-GUINEA | SURFACE PROTEIN-1 | Antigens, Protozoan - immunology | Age Factors | Immunoglobulin G - blood | Humans | Child, Preschool | Parasitemia - drug therapy | Plasmodium falciparum - immunology | Malaria, Falciparum - blood | Antibodies, Protozoan - blood | Immunoglobulin G - immunology | Antigens, Protozoan - blood | Child | Merozoites - immunology | Malaria, Falciparum - drug therapy | Enzyme-Linked Immunosorbent Assay | Antibodies, Protozoan - immunology | Parasitemia - immunology | Membrane Proteins - immunology | Antimalarials - therapeutic use | Parasitemia - blood | Animals | Artemisinins - therapeutic use | Merozoite Surface Protein 1 - immunology | Adolescent | Malaria, Falciparum - immunology | Protozoan Proteins - immunology | Microbial Immunity and Vaccines
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7. Full Text Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors
by Sheehy, Susanne H and Duncan, Christopher JA and Elias, Sean C and Collins, Katharine A and Ewer, Katie J and Spencer, Alexandra J and Williams, Andrew R and Halstead, Fenella D and Moretz, Samuel E and Miura, Kazutoyo and Epp, Christian and Dicks, Matthew DJ and Poulton, Ian D and Lawrie, Alison M and Berrie, Eleanor and Moyle, Sarah and Long, Carole A and Colloca, Stefano and Cortese, Riccardo and Gilbert, Sarah C and Nicosia, Alfredo and Hill, Adrian VS and Draper, Simon J
Molecular Therapy, ISSN 1525-0016, 12/2011, Volume 19, Issue 12, pp. 2269 - 2276
Efficacy trials of antibody-inducing protein-in-adjuvant vaccines targeting the blood-stage malaria parasite have so far shown disappointing results. The... 
APICAL MEMBRANE ANTIGEN-1 | MEDICINE, RESEARCH & EXPERIMENTAL | RHESUS-MONKEYS | ADENOVIRAL VECTORS | PROTECTIVE IMMUNITY | IN-VITRO | MEROZOITE SURFACE PROTEIN-1 | T-CELL RESPONSES | MEDIATED-IMMUNITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | MALARIA VACCINES | ADJUVANT VACCINES | Malaria, Falciparum - therapy | Humans | Vaccination | Merozoite Surface Protein 1 - genetics | Male | Macaca mulatta | Genetic Vectors - therapeutic use | Plasmodium falciparum - immunology | Vaccinia virus - genetics | CD4-Positive T-Lymphocytes - immunology | Young Adult | Malaria, Falciparum - blood | Flow Cytometry | Immunoglobulin G - immunology | Plasmodium falciparum - genetics | Adenoviridae - genetics | Adult | Female | Enzyme-Linked Immunosorbent Assay | Adjuvants, Immunologic | Antibodies, Protozoan - immunology | Merozoite Surface Protein 1 - blood | Blotting, Western | Animals | Merozoite Surface Protein 1 - immunology | Fluorescent Antibody Technique | Malaria, Falciparum - immunology | Immunologic Memory | Mice | Immunity, Cellular | Original
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8. Full Text Immunogenicity of the Plasmodium vivax merozoite surface protein 1 paralog in the induction of naturally acquired antibody and memory B cell responses
by Min, Hay Man Kyaw and Changrob, Siriruk and Soe, Phyu Thwe and Han, Jin Hee and Muh, Fauzi and Lee, Seong-Kyun and Chootong, Patchanee and Han, Eun-Taek
Malaria Journal, ISSN 1475-2875, 08/2017, Volume 16, Issue 1, pp. 354 - 12
Background: The Plasmodium vivax merozoite surface protein 1 paralog (PvMSP1P-19) is a glycosylphosphatidylinositol (GPI)-anchored blood-stage protein that is... 
Immunogenicity | Plasmodium vivax | Merozoite surface protein 1 paralog | INFECTIOUS DISEASES | AMAZON | FALCIPARUM | INHIBITORY ANTIBODIES | DUFFY-BINDING-PROTEIN | TROPICAL MEDICINE | REGION | VACCINE CANDIDATE | MALARIA | INFECTION | LIGAND | PARASITOLOGY | Antigens, Protozoan - immunology | Immunoglobulin G - blood | Humans | Middle Aged | Protozoan Proteins - genetics | Young Adult | Antibodies, Protozoan - blood | Immunity, Humoral | Plasmodium vivax - pathogenicity | Malaria Vaccines - immunology | Adult | Antigens, Protozoan - genetics | Malaria, Vivax - prevention & control | Erythrocytes - immunology | Antibody Formation - immunology | Enzyme-Linked Immunosorbent Assay | Antibodies, Protozoan - immunology | Plasmodium vivax - immunology | B-Lymphocytes - immunology | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Adolescent | Malaria, Vivax - immunology | Erythrocytes - parasitology | Protozoan Proteins - immunology | Antigens | Immune response | Immunoglobulin G | Vaccines | B cells | Health aspects | Enzyme-linked immunosorbent assay
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9. Full Text Identification of Plasmodium falciparum reticulocyte binding protein homologue 5-interacting protein, PfRipr, as a highly conserved blood-stage malaria vaccine candidate
by Ntege, Edward H and Arisue, Nobuko and Ito, Daisuke and Hasegawa, Tomoyuki and Palacpac, Nirianne M.Q and Egwang, Thomas G and Horii, Toshihiro and Takashima, Eizo and Tsuboi, Takafumi
Vaccine, ISSN 0264-410X, 2016, Volume 34, Issue 46, pp. 5612 - 5622
Highlights • PfRipr is highly conserved target of immunity in Uganda P. falciparum isolates. • Anti-PfRipr IgG inhibited merozoite invasion of heterologous P.... 
Allergy and Immunology | PfRipr | Plasmodium falciparum | Malaria blood-stage vaccine | Growth inhibition | Polymorphism | MEDICINE, RESEARCH & EXPERIMENTAL | PFRH5 | PROTECTION | EFFICACY | CELL-FREE SYSTEM | IMMUNOLOGY | PARASITE-NEUTRALIZING ANTIBODIES | DISCOVERY | GENETIC DIVERSITY | INVASION | ERYTHROCYTES | ANTIGEN | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Reticulocytes - parasitology | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Antibodies, Protozoan - blood | Merozoite Surface Protein 1 - isolation & purification | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Protozoan Proteins - chemistry | Carrier Proteins - immunology | Plasmodium falciparum - chemistry | Rabbits | Antigens, Protozoan - chemistry | Merozoites - physiology | Recombinant Proteins - chemistry | Reticulocytes - metabolism | Polymorphism, Genetic | Cross Reactions | Merozoite Surface Protein 1 - administration & dosage | Carrier Proteins - genetics | Animals | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Uganda | Erythrocytes - parasitology | Protozoan Proteins - immunology | Vaccines | Malaria | Malaria vaccine | Protein binding | Antigens | Medical research | DNA binding proteins | Recombinant proteins | Genetic polymorphisms | Biological diversity | Anopheles | Analysis | Medicine, Experimental | Conflicts of interest | Laboratories | Genes | Erythrocytes
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10. Full Text Evaluation of Plasmodium vivax isolates in Thailand using polymorphic markers Plasmodium merozoite surface protein (PvMSP) 1 and PvMSP3
by Suphakhonchuwong, Nutnicha and Chaijaroenkul, Wanna and Rungsihirunrat, Kanchana and Na-Bangchang, Kesara and Kuesap, Jiraporn
Parasitology Research, ISSN 0932-0113, 12/2018, Volume 117, Issue 12, pp. 3965 - 3978
Malaria is a significant public health problem in several tropical countries including Thailand. The prevalence of Plasmodium vivax infection has been... 
Medical Microbiology | Plasmodium vivax | Biomedicine | Immunology | Microbiology | Merozoite surface protein 3 (MSP3) | Merozoite surface protein 1 (MSP1) | Polymorphism | PROTEIN-3-ALPHA | PROTECTION | CHLOROQUINE | GENETIC DIVERSITY | INVASION | REGIONS | MALARIA | INFECTION | PARASITOLOGY | Antigens, Protozoan - immunology | Malaria, Vivax - parasitology | Humans | Merozoite Surface Protein 1 - genetics | Plasmodium vivax - genetics | Genotype | Protozoan Proteins - genetics | Thailand | Merozoites | Polymerase Chain Reaction - methods | Animals | Polymorphism, Restriction Fragment Length | Merozoite Surface Protein 1 - immunology | Alleles | Malaria Vaccines - immunology | Plasmodium vivax - isolation & purification | Polymorphism, Genetic - genetics | Antigens, Protozoan - genetics | Protozoan Proteins - immunology | Proteins | Physiological aspects | Evaluation
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11. Full Text The Plasmodium vivax Merozoite Surface Protein 1 Paralog Is a Novel Erythrocyte-Binding Ligand of P. vivax
by Yang Cheng and Yue Wang and Daisuke Ito and Deok-Hoon Kong and Kwon-Soo Ha and Jun-Hu Chen and Feng Lu and Jian Li and Bo Wang and Eizo Takashima and Jetsumon Sattabongkot and Takafumi Tsuboi and Eun-Taek Han
Infection and Immunity, ISSN 0019-9567, 05/2013, Volume 81, Issue 5, pp. 1585 - 1595
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
ANTIBODIES | INFECTIOUS DISEASES | HUMORAL IMMUNE-RESPONSES | WHEAT-GERM | INVASION | VACCINE CANDIDATE ANTIGEN | FALCIPARUM | ESCHERICHIA-COLI | ANCHORED MEMBRANE-PROTEINS | HUMAN MALARIA PARASITE | IMMUNOLOGY | MSP1 PROTEIN | Recombinant Proteins - metabolism | Humans | Middle Aged | Antibodies, Protozoan | Male | Plasmodium vivax - immunology | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan | Young Adult | Animals | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Adolescent | Erythrocytes - metabolism | Fluorescent Antibody Technique | Malaria Vaccines - immunology | Adult | Female | Malaria, Vivax - immunology | Mice | Mice, Inbred BALB C | Host-Parasite Interactions | Erythrocytes - parasitology | Immunoglobulin G - metabolism | Fungal and Parasitic Infections
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12. Full Text Can prenatal malaria exposure produce an immune tolerant phenotype?: A prospective birth cohort study in Kenya
by Malhotra, Indu and Dent, Arlene and Mungai, Peter and Wamachi, Alex and Ouma, John H and Narum, David L and Muchiri, Eric and Tisch, Daniel J and King, Christopher L
PLoS Medicine, ISSN 1549-1277, 07/2009, Volume 6, Issue 7, p. e1000116
Background: Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or their soluble products, thereby stimulating T and B cell immune... 
IN-UTERO | RESPONSES | MEDICINE, GENERAL & INTERNAL | MEROZOITE SURFACE PROTEIN-1 | HUMAN PLACENTA | PLASMODIUM-FALCIPARUM INFECTION | INVASION-INHIBITORY ANTIBODIES | TIME QUANTITATIVE PCR | T-CELL | MATERNAL MALARIA | RECEPTOR-BINDING DOMAIN | Antigens, Protozoan - immunology | Prospective Studies | Kenya - epidemiology | Humans | T-Lymphocytes - parasitology | Male | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan - metabolism | Plasmodium falciparum | Antibodies, Protozoan - blood | Protozoan Proteins - metabolism | T-Lymphocytes - metabolism | Malaria, Falciparum - epidemiology | Adult | Antigens, Protozoan - blood | Female | Membrane Proteins - metabolism | Infant, Newborn | Cytokines - immunology | Maternal-Fetal Exchange - immunology | Fetal Blood - immunology | Cytokines - metabolism | Cells, Cultured | Immune Tolerance | Membrane Proteins - immunology | Pregnancy | Pregnancy Complications, Parasitic - immunology | Animals | Merozoite Surface Protein 1 - immunology | Malaria, Falciparum - immunology | Pregnancy Complications, Parasitic - epidemiology | T-Lymphocytes - immunology | Protozoan Proteins - immunology | Studies | Medical research | Parasites | Malaria | Newborn babies | Immune system
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