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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 32, pp. 13275 - 13280
The commitment of Plasmodium merozoites to invade red blood cells (RBCs) is marked by the formation of a junction between the merozoite and the RBC and the... 
Apposition | Antigens | Malaria | Erythrocytes | Erythrocyte invasion | Parasitism | Cell membranes | Parasites | Merozoites | Vacuoles | Moving junction | AMA1-RON2 | APICAL MEMBRANE ANTIGEN-1 | PARASITOPHOROUS VACUOLE | APICOMPLEXAN PARASITES | MULTIDISCIPLINARY SCIENCES | malaria | moving junction | ERYTHROCYTE INVASION | MALARIA VACCINE CANDIDATE | ANONYMOUS PROTEIN | TOXOPLASMA-GONDII | INHIBITORY ANTIBODY | FALCIPARUM MEROZOITES | Conserved Sequence - genetics | Hydrophobic and Hydrophilic Interactions - drug effects | Molecular Sequence Data | Protein Transport - drug effects | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Cytochalasin D - pharmacology | Fructose-Bisphosphate Aldolase - chemistry | Protozoan Proteins - metabolism | Protein Binding - drug effects | Merozoites - drug effects | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Cysteine - metabolism | Fructose-Bisphosphate Aldolase - metabolism | Binding Sites | Plasmodium falciparum - ultrastructure | Merozoites - metabolism | Amino Acid Sequence | Antibodies, Protozoan - immunology | Merozoites - ultrastructure | Erythrocytes - drug effects | Animals | Models, Biological | Plasmodium falciparum - pathogenicity | Erythrocytes - parasitology | Physiological aspects | Plasmodium | Genetic aspects | Research | Protein binding | Biological Sciences | AMA1–RON2
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2261 - 9
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 10, pp. 3743 - 3748
Despite the significance of Alzheimer's disease, the link between metal-associated amyloid-β (metal-Aβ) and disease etiology remains unclear. To elucidate this... 
Aggregation | Metal aggregates | Reactivity | Cell aggregates | Dimers | Amyloids | Alzheimers disease | Solar fibrils | Monomers | Metal ions | Amyloidogenesis | Amyloid-β peptide | Natural products | FIBRIL FORMATION | ALZHEIMERS-DISEASE | EGCG | MULTIDISCIPLINARY SCIENCES | amyloid-beta peptide | metal ions | MASS-SPECTROMETRY | PEPTIDE | natural products | MEROZOITE SURFACE PROTEIN-2 | amyloidogenesis | EPIGALLOCATECHIN GALLATE | ZINC-BINDING | AGGREGATION | POLYPEPTIDE | Alzheimer Disease - etiology | Camellia sinensis - chemistry | Plant Extracts - chemistry | Peptide Fragments - toxicity | Plant Extracts - pharmacology | Humans | Protein Conformation - drug effects | Amyloid beta-Peptides - drug effects | Metals - toxicity | Zinc - chemistry | Tandem Mass Spectrometry | Copper - chemistry | Neuroprotective Agents - pharmacology | Metals - chemistry | Alzheimer Disease - prevention & control | Nuclear Magnetic Resonance, Biomolecular | Catechin - pharmacology | Copper - toxicity | Neuroprotective Agents - chemistry | Amyloid beta-Peptides - toxicity | Copper - pharmacology | Models, Molecular | Peptide Fragments - chemistry | Alzheimer Disease - metabolism | Peptide Fragments - drug effects | Protein Binding | Zinc - toxicity | Catechin - analogs & derivatives | Amyloid beta-Peptides - chemistry | Zinc - pharmacology | Catechin - chemistry | Protein Multimerization - drug effects | Metals - pharmacology | Biological Sciences | Physical Sciences | amyloid-β peptide
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2008, Volume 4, Issue 3, pp. 203 - 213
Newly replicated Plasmodium falciparum parasites escape from host erythrocytes through a tightly regulated process that is mediated by multiple classes of... 
CYSTEINE PROTEASE | PARASITOPHOROUS VACUOLE | VINYL SULFONES | STREPTOLYSIN-O | MEROZOITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL INVASION | I CATHEPSIN-C | SERINE-PROTEASE | SUBTILISIN-LIKE PROTEASE-1 | ANTIGEN | Cysteine Endopeptidases - chemistry | Plasmodium falciparum - enzymology | Parasitic Sensitivity Tests | Protozoan Proteins - antagonists & inhibitors | Stereoisomerism | Humans | Molecular Conformation | Subtilisins - chemistry | Plasmodium falciparum - drug effects | Cysteine Endopeptidases - drug effects | Sulfones - pharmacology | Serine Endopeptidases - drug effects | Dose-Response Relationship, Drug | Antigens, Protozoan - metabolism | Protease Inhibitors - pharmacology | Antigens, Protozoan - drug effects | Cysteine Endopeptidases - metabolism | Protozoan Proteins - metabolism | Isocoumarins - pharmacology | Sulfones - chemistry | Malaria, Falciparum - metabolism | Protozoan Proteins - chemistry | Subtilisins - metabolism | Plasmodium falciparum - physiology | Peptides - chemistry | Protease Inhibitors - chemistry | Serine Endopeptidases - chemistry | Subtilisins - antagonists & inhibitors | Peptides - pharmacology | Host-Parasite Interactions - drug effects | Malaria, Falciparum - parasitology | Animals | Small Molecule Libraries | Erythrocytes - metabolism | Serine Endopeptidases - metabolism | Erythrocytes - parasitology | Isocoumarins - chemistry | Biochemistry | Biomedical research | Parasites | Malaria | Proteases | Erythrocytes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 22, pp. 8511 - 8516
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2017, Volume 12, Issue 12, p. e0188754
Severe malaria Even with the best available treatment, the mortality from severe Plasmodium falciparum malaria remains high. Typical features at death are high... 
ERYTHROCYTES | MULTIDISCIPLINARY SCIENCES | MEMBRANE PROTEIN-1 PFEMP1 | ANTIBODY | LIGAND | HEPARIN | ROSETTES | Area Under Curve | Humans | Middle Aged | Antimalarials - blood | Atovaquone - pharmacokinetics | Male | Parasitemia - drug therapy | Plasmodium falciparum - drug effects | Heparitin Sulfate - metabolism | Heparin - pharmacokinetics | Malaria, Falciparum - blood | Proguanil - pharmacokinetics | Merozoites - drug effects | Adult | Female | Plasmodium falciparum - physiology | Drug Therapy, Combination | Proguanil - blood | Heparin - pharmacology | Atovaquone - blood | Binding, Competitive | Severity of Illness Index | Malaria, Falciparum - drug therapy | Antimalarials - pharmacokinetics | Drug Administration Schedule | Administration, Oral | Merozoites - physiology | Parasite Load | Parasitemia - blood | Antimalarials - pharmacology | Erythrocytes - drug effects | Malaria, Falciparum - parasitology | Heparin - analogs & derivatives | Heparitin Sulfate - chemistry | Atovaquone - pharmacology | Adolescent | Heparin - blood | Parasitemia - parasitology | Aged | Infusions, Intravenous | Erythrocytes - parasitology | Drug Combinations | Proguanil - pharmacology | Plasmodium falciparum | Care and treatment | Malaria | Erythrocytes | Antimalarials | Dosage and administration | Research | Heparan sulfate | Vector-borne diseases | Health sciences | Intravenous administration | Atovaquone | Infections | Parasites | Sulfates | Patients | Merozoites | Molecular weight | Medicine | Studies | Infusion | Hospitals | Red blood cells | Proguanil | Heparin | Sulfate | Active control | Binding sites
Journal Article
Journal Article