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Bioimpacts, ISSN 2228-5660, 12/2018, Volume 8, Issue Suppl 1, pp. S1 - S129
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 466, Issue 7308, pp. 829 - 834
The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial and perivascular cells... 
PROGENITOR CELLS | OSTEOBLAST | OSTEOPONTIN | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | RECEPTOR | DIFFERENTIATION | NEURAL CREST | COOPERATION | EXPRESSION | Chondrocytes - cytology | Nestin | Multipotent Stem Cells - metabolism | Parathyroid Hormone - pharmacology | Cell Lineage - drug effects | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Multipotent Stem Cells - drug effects | Sympathetic Nervous System - physiology | Cell Division | Stromal Cells - drug effects | Osteoblasts - cytology | Hematopoietic Stem Cells - drug effects | Mesenchymal Stromal Cells - drug effects | Gene Expression Regulation - genetics | Osteoblasts - drug effects | Stromal Cells - metabolism | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Stem Cell Niche - cytology | Nerve Tissue Proteins - metabolism | Granulocyte Colony-Stimulating Factor - pharmacology | Animals | Chemokine CXCL12 - metabolism | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Hematopoietic Stem Cells - cytology | Stem Cell Niche - metabolism | Mice | Stem Cell Niche - drug effects | Osteoblasts - metabolism | Intermediate Filament Proteins - metabolism | Mesenchymal Stem Cell Transplantation | Stromal Cells - cytology | Cell Movement | Physiological aspects | Genetic aspects | Research | Bone marrow cells | Gene expression | Osteoblasts | Hematopoietic stem cells | Studies | Proteins | Bone marrow | Rodents | Stem cells
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and offer a cost-effective approach... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | toxicology | HUMAN NEOCORTEX | tissue engineering | DEVELOPMENTAL NEUROTOXICITY | differentiation | HUMAN BRAIN | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | FATTY-ACIDS | machine learning | CANCER | organoid | IN-VITRO | HUMAN CEREBRAL-CORTEX | MICROGLIA | GENE-EXPRESSION | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Biological Sciences
Journal Article
Stem cells (Dayton, Ohio), ISSN 1549-4918, 2010, Volume 28, Issue 3, pp. 564 - N/A
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types... 
N‐cadherin | Cell shape | Rac1 | Chondrogenesis | Smooth muscle cells | Mesenchymal stem cells | N-cadherin | MYOBLAST FUSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ADHESION | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | CYTOSKELETAL TENSION | DIFFERENTIATION | RHO-GTPASES | PROTEINS | HEMATOLOGY | MODULATION | MAMMARY EPITHELIAL-CELLS | Chondrocytes - cytology | Chondrogenesis - drug effects | Cadherins - metabolism | Humans | Extracellular Matrix - metabolism | Antigens, CD - genetics | Cell Lineage - drug effects | Transforming Growth Factor beta3 - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cadherins - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Cell Adhesion - genetics | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Mesenchymal Stromal Cells - metabolism | Up-Regulation - genetics | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion - drug effects | Cell Lineage - physiology | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Muscle Development - drug effects | rac1 GTP-Binding Protein - drug effects | Cell Differentiation - drug effects | Cell Shape - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 6, p. e39885
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 33, Issue 9, pp. 2629 - 2641
...). The effects on bone mesenchymal stem cell (MSC) osteogenic differentiation are studied systematically by various microscopic and biological characterization techniques... 
Advanced Basic Science | Dentistry | Osteogenic differentiation | Hierarchical topography | Cell spread | Mesenchymal stem cells | Titania nanotubes | RECRUITMENT | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | TIO2 NANOTUBES | ENGINEERING, BIOMEDICAL | IMPLANTS | FATE | ADHESION | GROWTH | GENE-EXPRESSION | DYNAMICS | SURFACES | Mesenchymal Stromal Cells - enzymology | Titanium - pharmacology | Bone Marrow Cells - enzymology | Cell Count | Alkaline Phosphatase - metabolism | Titanium - chemistry | Extracellular Matrix - metabolism | Sincalide - metabolism | Nanotubes - chemistry | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Bone Marrow Cells - drug effects | Osteogenesis - genetics | Nanotubes - ultrastructure | Mesenchymal Stromal Cells - drug effects | Calcification, Physiologic - drug effects | Bone Marrow Cells - cytology | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Rats | Cell Adhesion - drug effects | Collagen - secretion | Rats, Sprague-Dawley | Bone Marrow Cells - ultrastructure | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Animals | Cell Differentiation - drug effects | Staining and Labeling | Cell Proliferation - drug effects | Cell Cycle - drug effects | Biological products | Phosphatases | Analysis | Collagen | Genes | Stem cells | Fluorescence | Gene expression | Orthodontics
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20526
Background: Mesenchymal stem cells (MSCs) hold great promise for the treatment of difficult diseases... 
IN-VITRO | MYOCARDIAL-INFARCTION | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | MICE | STROMAL CELLS | HISTONE ACETYLATION | EXPRESSION | CARDIAC REPAIR | TRANSPLANTATION | Estrogens - pharmacology | Epigenesis, Genetic | Humans | Multipotent Stem Cells - metabolism | Fibroblast Growth Factor 2 - pharmacology | Cellular Senescence - drug effects | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Multipotent Stem Cells - drug effects | Osteogenesis - genetics | Cellular Senescence - genetics | Pluripotent Stem Cells - cytology | Osteogenesis - drug effects | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Cell Shape - drug effects | Pluripotent Stem Cells - metabolism | Acetylation - drug effects | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Pluripotent Stem Cells - drug effects | Cell Proliferation - drug effects | Histones - metabolism | DNA Methylation - drug effects | Stem cell research | Epigenetic inheritance | Tissue engineering | Genes | Stem cells | Fibroblast growth factors | Methylation | Cell differentiation | Cell culture | Disease | Mesenchyme | Laboratories | Oct-4 protein | Differentiation (biology) | Adipocytes | Osteoblasts | Biomedical materials | DNA methylation | Aging | Bone marrow | Biocompatibility | Life sciences | Acetylation | Expansion | Deoxyribonucleic acid--DNA | CpG islands | Fibroblast growth factor 2 | Cbfa-1 protein | Medical treatment | Gene expression | Medicine | Molecular modelling | Placenta | Osteoblastogenesis | Respiratory diseases | Morphology | Epigenetics | Histone H3 | Osteogenesis | Deoxyribonucleic acid | DNA
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 526, Issue 7571, pp. 131 - 135
.... Prevailing theories hypothesize that metastases are seeded by rare tumour cells with unique properties, which may function like stem cells in their ability to initiate and propagate metastatic tumours(2-5... 
INHIBITION | COMMITMENT | MULTIDISCIPLINARY SCIENCES | GROWTH | GENES | MARKERS | IDENTIFICATION | FATE | TUMORS | TRANSCRIPTOME ANALYSIS | MAMMARY-GLAND | Neoplastic Stem Cells - drug effects | Epithelial Cells - drug effects | Humans | Gene Expression Profiling | Epithelial-Mesenchymal Transition - genetics | Cell Differentiation - genetics | Flow Cytometry | Neoplasm Metastasis - drug therapy | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Cyclin-Dependent Kinases - antagonists & inhibitors | Single-Cell Analysis | Disease Models, Animal | Cell Separation | Epithelial Cells - pathology | Mice, SCID | Breast Neoplasms - drug therapy | Disease Progression | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Genes, myc - genetics | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mesoderm - metabolism | Mice | Cell Transformation, Neoplastic - drug effects | Cell Cycle - drug effects | Cell Transformation, Neoplastic - pathology | Mesoderm - pathology | Stem cells | Cancer cells | Development and progression | Breast cancer | Metastasis | Observations | Health aspects | Bone marrow | Principal components analysis | Gene expression | Tumors | Apoptosis
Journal Article