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1. Full Text Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk
by Marian Goicoechea and Soledad García de Vinuesa and Ursula Verdalles and Caridad Ruiz-Caro and Jara Ampuero and Abraham Rincón and David Arroyo and José Luño
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 08/2010, Volume 5, Issue 8, pp. 1388 - 1393
Background and objectives: Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data... 
MORTALITY | HYPERURICEMIA | EVENTS | ENDOTHELIAL DYSFUNCTION | UROLOGY & NEPHROLOGY | RENAL-DISEASE | OUTCOMES | CKD | SERUM URIC-ACID | Kidney Diseases - physiopathology | Prospective Studies | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Glomerular Filtration Rate - drug effects | C-Reactive Protein - metabolism | Time Factors | Cardiovascular Diseases - blood | Kidney Diseases - blood | Kidney Diseases - complications | Uric Acid - blood | Cardiovascular Diseases - etiology | Risk Assessment | Risk Factors | Inflammation Mediators - blood | Kaplan-Meier Estimate | Proportional Hazards Models | Kidney Diseases - drug therapy | Treatment Outcome | Hospitalization | Biomarkers - blood | Gout Suppressants - adverse effects | Chi-Square Distribution | Hyperuricemia - etiology | Disease Progression | Spain | Hyperuricemia - prevention & control | Gout Suppressants - therapeutic use | Allopurinol - therapeutic use | Hyperuricemia - blood | Allopurinol - adverse effects | Aged | Chronic Disease | Index Medicus | Original
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2. Full Text Chronic Inflammatory Disorders and Risk of Type 2 Diabetes Mellitus, Coronary Heart Disease, and Stroke: A Population-Based Cohort Study
by Dregan, Alex and Charlton, Judith and Chowienczyk, Phil and Gulliford, Martin C
Circulation, ISSN 0009-7322, 09/2014, Volume 130, Issue 10, pp. 837 - 844
BACKGROUND—This study sought to evaluate whether risks of diabetes mellitus and cardiovascular disease are elevated across a range of organ-specific and... 
Biomarker | Stroke | Inflammation | Coronary disease | Diabetes mellitus | C-REACTIVE PROTEIN | RHEUMATOID-ARTHRITIS | MORTALITY | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | SURVIVAL ANALYSIS | PREVENTION | diabetes mellitus | biomarker | stroke | coronary disease | PRIMARY-CARE | inflammation | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | PSORIASIS | Humans | Middle Aged | Rheumatic Diseases - blood | Coronary Disease - epidemiology | Male | Case-Control Studies | Inflammation - blood | Diabetes Mellitus, Type 2 - epidemiology | Psoriasis - complications | Inflammation - complications | C-Reactive Protein - metabolism | Aged, 80 and over | Adult | Female | Stroke - epidemiology | Inflammatory Bowel Diseases - complications | Psoriasis - blood | Risk Factors | Autoimmune Diseases - complications | United Kingdom | Inflammatory Bowel Diseases - blood | Biomarkers - blood | Autoimmune Diseases - blood | Rheumatic Diseases - complications | Aged | Chronic Disease | Cohort Studies | Type 2 diabetes | Care and treatment | Mortality | Analysis | Risk factors | Index Medicus | Abridged Index Medicus
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3. Full Text Objective vs. self-reported physical activity and sedentary time: Effects of measurement method on relationships with risk biomarkers
by Celis-Morales, Carlos A and Perez-Bravo, Francisco and Ibañez, Luis and Salas, Carlos and Bailey, Mark E. S and Gill, Jason M. R
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36345 - e36345
Purpose: Imprecise measurement of physical activity variables might attenuate estimates of the beneficial effects of activity on health-related outcomes. We... 
MORTALITY | OBESITY | ENERGY-EXPENDITURE | LIFE-STYLE | BIOLOGY | CARDIOVASCULAR-DISEASE | ADULTS | ACCELEROMETER | SITTING TIME | TYPE-2 DIABETES-MELLITUS | ACTIVITY QUESTIONNAIRE | Blood Pressure | Humans | Middle Aged | Risk Factors | Self Report | Insulin Resistance | Vascular Diseases - physiopathology | Biomarkers - blood | Insulin - blood | Motor Activity | Metabolic Syndrome - blood | Fasting - blood | Adolescent | Metabolic Syndrome - physiopathology | Triglycerides - blood | Cholesterol, HDL - blood | Adult | Cholesterol, LDL - blood | Female | Aged | Blood Glucose - metabolism | Vascular Diseases - blood | Measurement | Type 2 diabetes | Low density lipoproteins | Triglycerides | Social aspects | Risk factors | Body mass index | Blood circulation disorders | Blood cholesterol | Insulin resistance | Health aspects | Methods | Trans fatty acids | Lipoproteins (low density) | Physical activity | Body fat | Bias | Homeostasis | Cardiovascular disease | Glucose | Metabolic syndrome | Blood | Vascular diseases | Questionnaires | Classification | Measurement methods | Blood pressure | Life sciences | Bioindicators | Lipoproteins (high density) | Accelerometers | Regression coefficients | Obesity | Nutrition | Health risks | Dose-response effects | Risk analysis | Insulin | Cholesterol | Quality of life | Studies | Body mass | Biomarkers | Adults | Diabetes | Index Medicus
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4. Full Text Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults
by Neeland, Ian J and Ayers, Colby R and Rohatgi, Anand K and Turer, Aslan T and Berry, Jarett D and Das, Sandeep R and Vega, Gloria L and Khera, Amit and McGuire, Darren K and Grundy, Scott M and Lemos, James A
Obesity, ISSN 1930-7381, 09/2013, Volume 21, Issue 9, pp. E439 - E447
Objective : Visceral (VAT) and abdominal subcutaneous (SAT) adipose tissues contribute to obesity but may have different metabolic and atherosclerosis risk... 
Metabolic Syndrome - etiology | Multivariate Analysis | Dyslipidemias - complications | Humans | Middle Aged | Male | Obesity - blood | Inflammation - blood | Atherosclerosis - etiology | Metabolic Syndrome - blood | Subcutaneous Fat - metabolism | C-Reactive Protein - metabolism | Leptin - blood | Inflammation Mediators - metabolism | Adult | Cholesterol, LDL - blood | Female | Heart Diseases - blood | Body Fat Distribution | Biomarkers - metabolism | Atherosclerosis - pathology | Obesity - complications | Insulin Resistance | Cholesterol, VLDL - blood | Intra-Abdominal Fat - metabolism | Subcutaneous Fat - pathology | Obesity - metabolism | Obesity - pathology | Adiponectin - blood | Atherosclerosis - blood | Heart Diseases - etiology | Phenotype | Cholesterol, HDL - blood | Intra-Abdominal Fat - pathology | Metabolic Syndrome - pathology | Heart Diseases - pathology | Studies | Obesity | Insulin resistance | Weight control | Cholesterol | Index Medicus | Lipoproteins | Inflammation | Diabetes | Atherosclerosis
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5. Full Text Early Control of PTH and FGF23 in Normophosphatemic CKD Patients: A New Target in CKD-MBD Therapy?
by Rodrigo B. Oliveira and Ana L.E. Cancela and Fabiana G. Graciolli and Luciene M. Dos Reis and Sérgio A. Draibe and Lilian Cuppari and Aluizio B. Carvalho and Vanda Jorgetti and Maria E. Canziani and Rosa M.A. Moysés
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 02/2010, Volume 5, Issue 2, pp. 286 - 291
Background and objectives: Levels of parathyroid hormone (PTH) and the phosphaturic hormone FGF23, a fibroblast growth factor (FGF) family member, increase... 
VITAMIN-D | PHOSPHORUS | HYPERPARATHYROIDISM | REGULATING PHOSPHATE | DIALYSIS PATIENTS | METABOLISM | FIBROBLAST-GROWTH-FACTOR-23 | CALCIUM | UROLOGY & NEPHROLOGY | NUTRITION | CHRONIC KIDNEY-DISEASE | Humans | Middle Aged | Male | Polyamines - therapeutic use | Parathyroid Hormone - blood | Bone Diseases, Metabolic - drug therapy | Calcium Compounds - therapeutic use | Time Factors | Phosphates - blood | Adult | Bone Diseases, Metabolic - blood | Female | Acetates - therapeutic use | Kidney Diseases - blood | Kidney Diseases - complications | Sevelamer | Chelating Agents - therapeutic use | Hyperparathyroidism, Secondary - drug therapy | Bone Diseases, Metabolic - etiology | Kidney Diseases - drug therapy | Treatment Outcome | Biomarkers - blood | Hyperparathyroidism, Secondary - blood | Pilot Projects | Fibroblast Growth Factors - blood | Hyperparathyroidism, Secondary - etiology | Chronic Disease | Index Medicus | Original
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6. Full Text Relationship of apolipoproteins A-1 and b, and lipoprotein(a) to cardiovascular outcomes: The aim-high trial (atherothrombosis intervention in metabolic syndrome with low HDL/high triglyceride and impact on global health outcomes)
by Albers, John J and Slee, April and O'Brien, Kevin D and Robinson, Jennifer G and Kashyap, Moti L and Kwiterovich Jr, Peter O and Xu, Ping and Marcovina, Santica M
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2013, Volume 62, Issue 17, pp. 1575 - 1579
Objectives This study sought to examine the relationship between baseline and on-study apolipoproteins (apo) A-1 and B and lipoprotein(a) [Lp(a)] levels and... 
niacin | simvastatin | apolipoproteins | cardiovascular risk | lipoprotein(a) | CARDIAC & CARDIOVASCULAR SYSTEMS | CHOLESTEROL | DISEASE | RISK | Hypertriglyceridemia - drug therapy | Prospective Studies | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Male | Apolipoproteins B - blood | Metabolic Syndrome - drug therapy | Niacin - administration & dosage | Metabolic Syndrome - blood | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Lipoprotein(a) - blood | Drug Therapy, Combination | Metabolic Syndrome - epidemiology | Double-Blind Method | Simvastatin - administration & dosage | Treatment Outcome | Hypoalphalipoproteinemias - blood | Biomarkers - blood | Hypoalphalipoproteinemias - epidemiology | Hypertriglyceridemia - blood | Hypertriglyceridemia - epidemiology | Triglycerides - blood | Cholesterol, HDL - blood | Hypoalphalipoproteinemias - drug therapy | Aged | Apolipoprotein A-I - blood | Index Medicus | Abridged Index Medicus | LIPOPROTEIN(A) | APOLIPOPROTEINS | SIMVASTATIN | CARDIOVASCULAR RISK | NIACIN
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7. Full Text Associations between dietary inflammatory index and inflammatory markers in the Asklepios Study
by Shivappa, Nitin and Hébert, James R and Rietzschel, Ernst R and De Buyzere, Marc L and Langlois, Michel and Debruyne, Evi and Marcos, Ascensión and Huybrechts, Inge
British Journal of Nutrition, ISSN 0007-1145, 02/2015, Volume 113, Issue 4, pp. 665 - 671
Previous research has shown that nutrients and certain food items influence inflammation. However, little is known about the associations between diet, as a... 
Cytokines | Diet | Inflammation: Inflammatory markers | Chronic disease risk | C-REACTIVE PROTEIN | METABOLIC SYNDROME | MEDITERRANEAN DIET | RISK | Inflammation | Inflammatory markers | FATTY-ACIDS | CANCER | NUTRITION & DIETETICS | CARDIOVASCULAR-DISEASE | LEUKOCYTE COUNT | CORONARY-HEART-DISEASE | HEALTHY-MEN | Cardiovascular Diseases - etiology | Up-Regulation | Belgium - epidemiology | Cross-Sectional Studies | Diet - adverse effects | Diet Surveys | Humans | Middle Aged | Risk Factors | Inflammation Mediators - blood | Homocysteine - blood | Male | Biomarkers - blood | Cardiovascular Diseases - immunology | Interleukin-6 - blood | Diet - ethnology | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Adult | Female | Longitudinal Studies | Biomarkers | Inflammatory diseases | Index Medicus
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8. Full Text Expanding the Psoriasis Disease Profile: Interrogation of the Skin and Serum of Patients with Moderate-to-Severe Psoriasis
by Suárez-Fariñas, Mayte and Li, Katherine and Fuentes-Duculan, Judilyn and Hayden, Karen and Brodmerkel, Carrie and Krueger, James G
Journal of Investigative Dermatology, ISSN 0022-202X, 11/2012, Volume 132, Issue 11, pp. 2552 - 2564
Psoriasis is a complex disease with an expanding definition of its pathological features. We sought to expand/refine the psoriasis transcriptome using 85... 
PATHWAYS | DENDRITIC CELLS | SUSCEPTIBILITY LOCI | GENE-EXPRESSION | 1Q21 | RISK | KERATINOCYTES | MODULATION | GENOME-WIDE ASSOCIATION | DERMATOLOGY | Diabetes Mellitus - blood | Diabetes Mellitus - genetics | Humans | Middle Aged | Transcriptome | Male | Cardiovascular Diseases - genetics | Dermatitis - epidemiology | Psoriasis - genetics | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Adult | Female | Psoriasis - blood | Skin - pathology | Severity of Illness Index | Comorbidity | Dermatitis - genetics | Metabolic Diseases - epidemiology | Metabolic Diseases - blood | Biomarkers - blood | Dermatitis - blood | Psoriasis - epidemiology | Biopsy | Diabetes Mellitus - epidemiology | Metabolic Diseases - genetics | Cohort Studies | Index Medicus | Transcription | psoriasis vulgaris | Diabetes mellitus | Skin diseases | Cardiovascular diseases | Gene expression | Probes | Metabolic disorders | Original
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9. Full Text A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults
by Stanhope, Kimber L and Medici, Valentina and Bremer, Andrew A and Lee, Vivien and Lam, Hazel D and Nunez, Marinelle V and Chen, Guoxia X and Keim, Nancy L and Havel, Peter J
American Journal of Clinical Nutrition, ISSN 0002-9165, 06/2015, Volume 101, Issue 6, pp. 1144 - 1154
Background: National Health and Nutrition Examination Survey data show an increased risk of cardiovascular disease (CVD) mortality with an increased intake of... 
Apolipoprotein CIII | Uric acid | Fructose | Risk factors | Sugar | risk factors | METABOLIC SYNDROME | BLOOD-LIPIDS | FOOD-INTAKE | fructose | INSULIN SENSITIVITY | ORAL FRUCTOSE | apolipoprotein CIII | SERUM URIC-ACID | LIVER FAT | NUTRITION & DIETETICS | ENERGY-EXPENDITURE | SUCROSE | POSTPRANDIAL TRIGLYCERIDES | sugar | uric acid | High Fructose Corn Syrup - administration & dosage | Nutrition Surveys | Humans | Sweetening Agents - adverse effects | Male | Apolipoproteins B - blood | Dose-Response Relationship, Drug | Young Adult | Cardiovascular Diseases - blood | Adult | Cholesterol, LDL - blood | Female | Postprandial Period - drug effects | Uric Acid - blood | Beverages | Body Mass Index | High Fructose Corn Syrup - adverse effects | Fasting | Double-Blind Method | Risk Factors | Apolipoprotein C-III - blood | Waist Circumference | Adolescent | Triglycerides - blood | Cholesterol, HDL - blood | Blood Glucose - metabolism | Sweetening Agents - administration & dosage | Intervention | Lipids | Cardiovascular disease | Lipoproteins | Index Medicus | Abridged Index Medicus
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10. Full Text Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation
by Lassenius, Mariann I and Pietiläinen, Kirsi H and Kaartinen, Kati and Pussinen, Pirkko J and Syrjänen, Jaana and Forsblom, Carol and Pörsti, Ilkka and Rissanen, Aila and Kaprio, Jaakko and Mustonen, Jukka and Groop, Per-Henrik and Lehto, Markku and FinnDiane Study Grp and FinnDiane Study Group and on behalf of the FinnDiane Study Group
Diabetes Care, ISSN 0149-5992, 08/2011, Volume 34, Issue 8, pp. 1809 - 1815
OBJECTIVE-To investigate whether bacterial lipopolysaccharide (LPS) activity in human serum is associated with the components of the metabolic syndrome (MetS)... 
IGA NEPHROPATHY | DIABETIC-NEPHROPATHY | RISK-FACTORS | PROGRESSION | DISEASE | ENDOCRINOLOGY & METABOLISM | Lipopolysaccharides - blood | Metabolic Syndrome - blood | Dyslipidemias - blood | Insulin Resistance - physiology | Albuminuria - blood | Diabetes Mellitus, Type 1 - blood | Humans | Triglycerides - blood | Kidney Diseases - blood | Glomerulonephritis, IGA - blood | Obesity - blood | Inflammation - blood | Obesity | Medical research | Albumin | Development and progression | Inflammation | Research | Immunoglobulin A | Cholesterol | Type 1 diabetes | Medicine, Experimental | Insulin resistance | Kidney diseases | Mitogens | Studies | Bacterial infections | Diabetes | Index Medicus | Original Research
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11. Full Text Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
by Palmer, Tom M and Nordestgaard, Børge G and Benn, Marianne and Tybjærg-Hansen, Anne and Davey Smith, George and Lawlor, Debbie A and Timpson, Nicholas J
BMJ : British Medical Journal, ISSN 0959-8138, 7/2013, Volume 347, Issue 7919, pp. 13 - 13
Objectives To assess the associations between both uric acid levels and hyperuricaemia, with ischaemic heart disease and blood pressure, and to explore the... 
Heart | RESEARCH | Body mass index | Observational research | Genetic variation | Predisposing factors | Myocardial ischemia | Blood pressure | Instrumental variables | Uric acid | Blood plasma | MORTALITY | TRANSPORTER SLC2A9 | ALL-CAUSE | MEDICINE, GENERAL & INTERNAL | SERUM URATE | GENERAL-POPULATION | MYOCARDIAL-INFARCTION | CARDIOVASCULAR-DISEASE | BODY-MASS INDEX | RISK | CORONARY-ARTERY-DISEASE | Body Mass Index | Myocardial Ischemia - genetics | Prospective Studies | Blood Pressure - genetics | Humans | Middle Aged | Myocardial Ischemia - blood | Male | Hyperuricemia - etiology | Hyperuricemia - genetics | Regression Analysis | Mendelian Randomization Analysis | Denmark | Adult | Female | Aged | Uric Acid - blood | Genotype & phenotype | Cardiovascular disease | Genetics | Index Medicus | Abridged Index Medicus
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