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CURRENT OPINION IN GENETICS & DEVELOPMENT, ISSN 0959-437X, 06/2018, Volume 50, pp. 60 - 67
Insulin resistance underpins the link between obesity and most of its associated metabolic disorders including type 2 diabetes, fatty liver disease,... 
METABOLIC SYNDROME | OBESITY | DERANGEMENTS | ACANTHOSIS NIGRICANS | MUTATION | GENETICS & HEREDITY | GENERALIZED LIPODYSTROPHY | GLYCEMIC TRAITS | CLINICAL-FEATURES | SEIP CONGENITAL LIPODYSTROPHY | BODY | CELL BIOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169309 - e0169309
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2010, Volume 120, Issue 3, pp. 744 - 755
Wolfram syndrome is an autosomal-recessive disorder characterized by insulin-dependent diabetes mellitus, caused by nonautoimmune loss of beta cells, and... 
DIABETES-MELLITUS | MEDICINE, RESEARCH & EXPERIMENTAL | WFS1 GENE | UNFOLDED PROTEIN RESPONSE | HUMAN HRD1 | PANCREATIC BETA-CELLS | PSYCHIATRIC-ILLNESS | ENDOPLASMIC-RETICULUM STRESS | OPTIC ATROPHY | ATF6 | TRANSMEMBRANE PROTEIN | Humans | Ubiquitin - metabolism | Cercopithecus aethiops | Endoplasmic Reticulum - metabolism | Wolfram Syndrome - genetics | Activating Transcription Factor 6 - genetics | Wolfram Syndrome - pathology | Endoplasmic Reticulum - pathology | Insulin-Secreting Cells - metabolism | Trans-Activators - genetics | Membrane Proteins - metabolism | Calmodulin-Binding Proteins - genetics | Endoplasmic Reticulum - genetics | Signal Transduction | Gene Expression Regulation - genetics | Membrane Proteins - genetics | Ubiquitin-Protein Ligases - metabolism | Rats | Wolfram Syndrome - metabolism | Calmodulin-Binding Proteins - metabolism | Ubiquitin - genetics | Unfolded Protein Response | Proteasome Endopeptidase Complex - genetics | Activating Transcription Factor 6 - metabolism | Animals | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Insulin-Secreting Cells - pathology | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | COS Cells | Ubiquitination - genetics | Ubiquitin | Care and treatment | Pancreatic beta cells | Genetic disorders | Physiological aspects | Genetic aspects | Research | Gene expression | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2010, Volume 6, Issue 3, pp. e1000874 - e1000874
Journal Article
Nature, ISSN 0028-0836, 03/2008, Volume 452, Issue 7186, pp. 429 - 435
Identifying variations in DNA that increase susceptibility to disease is one of the primary aims of genetic studies using a forward genetics approach. However,... 
QUANTITATIVE TRAIT LOCI | SEGREGATING MOUSE-POPULATION | HEART MITOCHONDRIAL PROTEOME | DETERMINING ATHEROSCLEROSIS SUSCEPTIBILITY | MULTIDISCIPLINARY SCIENCES | TISSUE-SPECIFIC EXPRESSION | GENE-EXPRESSION | FAMILIAL COMBINED HYPERLIPIDEMIA | FACTOR-H POLYMORPHISM | APOLIPOPROTEIN-A-II | UPSTREAM TRANSCRIPTION FACTOR-1 | Chromosomes, Mammalian - genetics | Phosphoprotein Phosphatases - metabolism | Apolipoprotein A-II - genetics | Male | Metabolic Syndrome - metabolism | Obesity - genetics | Lod Score | Adipose Tissue - metabolism | Female | Metabolic Syndrome - enzymology | Genetic Predisposition to Disease - genetics | Reproducibility of Results | Gene Regulatory Networks - genetics | Lipoprotein Lipase - genetics | Membrane Proteins - genetics | Ribosomal Proteins - genetics | Liver - metabolism | Linkage Disequilibrium | Obesity - metabolism | Macrophages - metabolism | Phenotype | Animals | Phosphoprotein Phosphatases - genetics | Metabolic Syndrome - genetics | Phosphoprotein Phosphatases - deficiency | Genetic Variation - genetics | Mice | Obesity - enzymology | Quantitative Trait Loci | Quantitative trait loci | Molecular neurobiology | Disease susceptibility | Genetic aspects | Research | Genetic variation | Obesity | Integrated approach | Biomedical research | Gene expression | Genomics | Index Medicus | Lipoprotein Lipase | Liver | Apolipoprotein A-II | Metabolic Syndrome X | Macrophages | Gene Regulatory Networks | Life Sciences | Adipose Tissue | Phosphoprotein Phosphatases | Genetic Predisposition to Disease | Biochemistry, Molecular Biology | Variation (Genetics) | Chromosomes, Mammalian | Membrane Proteins | Molecular biology | Ribosomal Proteins
Journal Article
Diabetes, ISSN 0012-1797, 04/2011, Volume 60, Issue 4, pp. 1329 - 1339
Journal Article
Journal Article