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PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0175486
We optically measured effects of orally available ivacaftor (Kalydeco (R)) on sweat rates of identified glands in 3 R117H subjects, each having a unique set of... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | GLANDS | GENE | MESSENGER-RNA TRANSCRIPTS | PARTIAL PENETRANCE | MULTIDISCIPLINARY SCIENCES | CODING SEQUENCES | MUTATION | DISEASE | CYSTIC-FIBROSIS | CFTR POTENTIATOR | Muscarinic Agonists - pharmacology | Sweat - secretion | Humans | Male | Quinolones - pharmacology | Aminophenols - pharmacology | Methacholine Chloride - administration & dosage | Gene Deletion | Methacholine Chloride - pharmacology | Adrenergic beta-Agonists - administration & dosage | Adult | Female | Injections, Intradermal | Muscarinic Agonists - administration & dosage | Administration, Oral | Chloride Channel Agonists - pharmacology | Adrenergic beta-Agonists - pharmacology | Sweating - genetics | Exons - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Sweating - drug effects | Quinolones - administration & dosage | Ion Channel Gating - genetics | Analysis of Variance | Chloride Channel Agonists - administration & dosage | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mutation | Aminophenols - administration & dosage | Ion Channel Gating - drug effects | Ivacaftor | Care and treatment | Gene mutations | Methacholine | Cystic fibrosis | Dosage and administration | Research | Wine | Pediatrics | Acetylcholine receptors (muscarinic) | Laboratories | Linkage disequilibrium | Glands | Biology | Iontophoresis | Membrane conductance | Chloride | Intestine | Anion channels | Genetics | Physiology | Children | Sweat | Digestive tract | Gating | Channel opening | Secretion | Channel gating | Bioassays | Organs | Chloride transport | Ion transport | Cultures | Medical screening | Medicine | Clear cells | Lungs | Alleles | In vivo methods and tests | Conductance | Cystic fibrosis transmembrane conductance regulator | Molecular biology
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2010, Volume 181, Issue 7, pp. 699 - 704
Rationale. Patients with asthma exhibit variable response to inhaled corticosteroids (ICS). Vitamin D is hypothesized to exert effects on phenotype and... 
Treatment | Glucocorticoids | Vitamin D | Asthma | treatment | 25-HYDROXYVITAMIN-D LEVELS | vitamin D | MAP KINASE | PERSISTENT ASTHMA | asthma | NECROSIS-FACTOR-ALPHA | CORTICOSTEROID RESISTANCE | RESISTANT ASTHMA | HEALTHY-ADULTS | RESPIRATORY SYSTEM | KINASE PHOSPHATASE-1 | BODY-MASS INDEX | glucocorticoids | T-CELLS | CRITICAL CARE MEDICINE | Glucocorticoids - administration & dosage | Bronchodilator Agents - administration & dosage | Forced Expiratory Volume - drug effects | Bronchial Hyperreactivity - drug therapy | Humans | Tumor Necrosis Factor-alpha - blood | Vitamin D Deficiency - drug therapy | Cell Growth Processes - physiology | Male | Vitamin D Deficiency - physiopathology | Bronchial Hyperreactivity - blood | Drug Interactions | Vitamin D Deficiency - blood | Methacholine Chloride - administration & dosage | Asthma - blood | Bronchial Hyperreactivity - physiopathology | Adult | Female | Vitamin D - administration & dosage | Bronchodilator Agents - adverse effects | Dual Specificity Phosphatase 1 - biosynthesis | Glucocorticoids - adverse effects | Body Mass Index | Dexamethasone - administration & dosage | Asthma - physiopathology | Cross-Sectional Studies | Cell Growth Processes - drug effects | Administration, Inhalation | Lung - physiopathology | Asthma - drug therapy | Vitamin D - blood | Glucocorticoids - pharmacology | Interleukin-10 - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | B. Asthma and Allergy
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77114
To assess CFTR function in vivo, we developed a bioassay that monitors and compares CFTR-dependent and CFTR-independent sweat secretion in parallel for... 
MUCUS SECRETION | GENE-MUTATIONS | TRANSMEMBRANE-CONDUCTANCE-REGULATOR | FLUID SECRETION | MESSENGER-RNA TRANSCRIPTS | CHRONIC-PANCREATITIS | SUBMUCOSAL GLANDS | MULTIDISCIPLINARY SCIENCES | CODING SEQUENCES | POTENTIAL DIFFERENCE | CYSTIC-FIBROSIS HETEROZYGOTES | Sweat - drug effects | Sweat - secretion | Humans | Isoproterenol - administration & dosage | Sweat Glands - secretion | Male | Dose-Response Relationship, Drug | Time Factors | Methacholine Chloride - administration & dosage | Adrenergic beta-Agonists - administration & dosage | Adult | Female | Injections, Intradermal | Aminophylline - administration & dosage | Sweat Glands - drug effects | Cystic Fibrosis - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Purinergic P1 Receptor Antagonists - administration & dosage | Muscarinic Agonists | Muscarinic Antagonists - administration & dosage | Cystic Fibrosis - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Heterozygote | Atropine - administration & dosage | Mutation | Measurement | Cystic fibrosis | Potentiation | Drugs | Pediatrics | Sweating | Bioassay | Calcium | Acetylcholine receptors (muscarinic) | Laboratories | Secretion | Glands | Bioassays | Heterozygotes | Medicine | Receptors | Bubbles | Chloride | Methacholine | In vivo methods and tests | Drug therapy | Sweat | Nonlinear systems
Journal Article
Journal of Aerosol Medicine and Pulmonary Drug Delivery, ISSN 1941-2711, 06/2016, Volume 29, Issue 3, pp. 260 - 272
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 8, pp. 3475 - 3487
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2012, Volume 53, Issue 7, pp. 1431 - 1439
Journal Article
American journal of respiratory and critical care medicine, ISSN 1073-449X, 10/2018, Volume 198, Issue 8, pp. 988 - 990
[...]expected pulmonary deposition would be the IM multiplied by the RF. When multiplied by the RF, in this case 0.76 (8), the expected deposition would be... 
FEV1 | RESPIRATORY SYSTEM | DEPOSITION | PD20 | CRITICAL CARE MEDICINE | Bronchial Provocation Tests - instrumentation | Bronchial Provocation Tests - methods | Societies, Medical | Methacholine Chloride - administration & dosage | Humans | Nebulizers and Vaporizers | Laboratories | Measurement techniques | Cystic fibrosis | Adults | Respiration | Drug dosages | Asthma
Journal Article