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Biological Chemistry, ISSN 1431-6730, 11/2010, Volume 391, Issue 11, pp. 1249 - 1264
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0136822
Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The... 
AMINO-ACID-METABOLISM | OXIDATIVE STRESS | DNA METHYLATION | LIQUID-CHROMATOGRAPHY | NITRIC-OXIDE SYNTHASE | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | FOLLOW-UP | STEATOHEPATITIS | ONE-CARBON METABOLISM | MASS-SPECTROMETRY | Glycine N-Methyltransferase - metabolism | Blood Chemical Analysis | Homocysteine - metabolism | Glutathione - biosynthesis | Diet, High-Fat | Female | Metabolic Networks and Pathways - physiology | Cysteine - metabolism | Dipeptides - metabolism | Betaine-Homocysteine S-Methyltransferase - metabolism | Acyl Coenzyme A - metabolism | B-Lymphocytes - metabolism | Methionine - metabolism | Liver - metabolism | Mice, Inbred C57BL | Metabolome | Adenosylhomocysteinase - metabolism | Methionine Adenosyltransferase - metabolism | DNA Methylation - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Cystathionine beta-Synthase - metabolism | Random Allocation | Animals | 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - metabolism | Mice | Fatty liver | Physiological aspects | Development and progression | Genetic aspects | Research | Homocysteine | Amino acid metabolism | Transcription factors | Adenosylmethionine | High cholesterol diet | Bcl-2 protein | Laboratories | Liver | Glycine | Caspase-3 | Proteins | Elevation | Arginine | Betaine | Rodents | DNA methylation | Deoxyribonucleic acid--DNA | Glutathione | Phosphatidylethanolamine | Liver diseases | Nutrition | 5-Methyltetrahydrofolate-homocysteine S-methyltransferase | Methionine | Glycine N-methyltransferase | c-Jun protein | Caspase | Betaine-homocysteine S-methyltransferase | Gene expression | Metabolism | Fatty acids | Lymphoma | Fatty-acid synthase | Cholesterol | Molecular chains | Substrates | Depletion | Lymphocytes B | Diet | Nitric oxide | Fibrosis | DNA methyltransferase | Methylation | Nuclear reactions | Polymethyl methacrylate | B-cell lymphoma | Deoxyribonucleic acid | DNA
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2005, Volume 38, Issue 6, pp. 698 - 710
Oxidation products of lipids, proteins, and DNA in the blood, plasma, and urine of rats were measured as part of a comprehensive, multilaboratory validation... 
Urine | Plasma | Free radicals | Rat | Lipid hydroperoxides | Methionine sulfoxidation | TBARS | Tyrosine products | MDA | CCl | Isoprostanes | DNA strand breaks | Protein carbonyls | 8-OHdG | BIOLOGICAL-MATERIALS | urine | LOW-DENSITY-LIPOPROTEIN | isoprostanes | MASS-SPECTROMETRY | protein carbonyls | AMINO-ACIDS | ENDOCRINOLOGY & METABOLISM | METHIONINE SULFOXIDE | CARBON-TETRACHLORIDE | free radicals | rat | BIOCHEMISTRY & MOLECULAR BIOLOGY | tyrosine products | PERFORMANCE LIQUID-CHROMATOGRAPHY | THIOBARBITURIC ACID-REACTIVITY | methionine sulfoxidation | CCl4 | IN-VIVO | FREE-RADICAL DAMAGE | plasma | lipid hydroperoxides | 8-OhdG | Immunoassay | Gas Chromatography-Mass Spectrometry | Oxidative Stress | Rats, Inbred F344 | Immunoblotting | Male | Oxygen - metabolism | Malondialdehyde - pharmacology | Carbon Tetrachloride Poisoning - metabolism | Time Factors | Deoxyguanosine - analogs & derivatives | Tyrosine - chemistry | Free Radicals | Methionine - metabolism | Liver - metabolism | Rats | Lipid Metabolism | DNA - metabolism | Carbon Tetrachloride - toxicity | Comet Assay | Hydrogen Peroxide - metabolism | Tyrosine - metabolism | Animals | Thiobarbituric Acid Reactive Substances | DNA Damage | Deoxyguanosine - pharmacology | Spectrophotometry | DNA/metabolism | Hydrogen Peroxide/metabolism | Malondialdehyde/pharmacology | Oxygen/metabolism | Liver/metabolism | Lipids/metabolism | Mass Fragmentography | Rats; Inbred F344 | Tyrosine/chemistry/metabolism | Methionine/metabolism | Carbon Tetrachloride/toxicity | Carbon Tetrachloride Poisoning/metabolism | Deoxyguanosine/analogs & derivatives/pharmacology
Journal Article
Laboratory Investigation, ISSN 0023-6837, 05/2012, Volume 92, Issue 5, pp. 713 - 723
Non-alcoholic steatohepatitis (NASH) is typically associated with pro-apoptotic caspase activation. A potential role for pro-inflammatory caspases remains... 
Inflammasome | Inflammation | Caspases | Non-alcoholic fatty liver disease | Non-alcoholic steatohepatitis | Fibrosis | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | APOPTOSIS | non-alcoholic fatty liver disease | MICE DEFICIENT | FATTY LIVER-DISEASE | INJURY | NONALCOHOLIC STEATOHEPATITIS | MODEL | PATHOLOGY | inflammation | inflammasome | fibrosis | caspases | HEPATIC STEATOSIS | non-alcoholic steatohepatitis | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Clodronic Acid - pharmacology | Fatty Liver - pathology | Actins - metabolism | Caspase 3 - metabolism | Hepatic Stellate Cells - metabolism | Caspase 1 - metabolism | Choline Deficiency - complications | Hepatocytes - pathology | Hepatocytes - metabolism | Fatty Liver - chemically induced | LIM Domain Proteins - metabolism | Liver Cirrhosis - chemically induced | Inflammation - metabolism | Caspase 3 - blood | Interleukin-1beta - metabolism | Choline Deficiency - metabolism | Liver Cirrhosis - metabolism | Muscle Proteins - metabolism | Antigens, Differentiation - metabolism | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Methionine - deficiency | Collagen Type I - metabolism | Fatty Liver - metabolism | Liver - metabolism | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Choline Deficiency - pathology | Kupffer Cells - drug effects | Mice, Knockout | Animals | Caspase 1 - genetics | Caspase 1 - deficiency | Liver Cirrhosis - pathology | Mice | Transforming Growth Factor beta - metabolism | Nonalcoholic fatty liver disease (NAFLD) | nonalcoholic steatohepatitis (NASH)
Journal Article
Journal Article
Amino Acids, ISSN 0939-4451, 1/2017, Volume 49, Issue 1, pp. 129 - 138
High levels of methionine (Met) and methionine sulfoxide (MetO) are found in several genetic abnormalities. Oxidative stress is involved in the pathophysiology... 
Life Sciences | Biochemistry, general | Oxidative stress | Analytical Chemistry | Life Sciences, general | Methionine sulfoxide | Biochemical Engineering | Proteomics | Neurobiology | Methionine | Delta aminolevulinic dehydratase | LIPID-PEROXIDATION | ANTIOXIDANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DELTA-AMINOLEVULINATE DEHYDRATASE | DAMAGE | HYPERMETHIONINEMIA | METABOLISM | FAT | ADENOSYLTRANSFERASE I/III DEFICIENCY | PROTEINS | RESIDUES | Glycine N-Methyltransferase - metabolism | Liver - pathology | Reactive Oxygen Species - metabolism | Kidney - pathology | Rats, Wistar | Glycine N-Methyltransferase - deficiency | Male | Methionine - pharmacology | Porphobilinogen Synthase - metabolism | Amino Acid Metabolism, Inborn Errors - metabolism | Kidney - metabolism | Sulfhydryl Compounds - metabolism | Liver - drug effects | Methionine - analogs & derivatives | Injections, Subcutaneous | Female | Urea - metabolism | Amino Acid Metabolism, Inborn Errors - pathology | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Amino Acid Metabolism, Inborn Errors - chemically induced | Kidney - drug effects | Methionine - metabolism | Liver - metabolism | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Cholesterol - metabolism | Enzyme Activation - drug effects | Triglycerides - metabolism | Catalase - metabolism | Animals | Glucose - metabolism | Oxidative Stress - drug effects | Lipid Peroxidation | Enzymes | Urea | Liver | Physiological aspects | Amino acids | Triglycerides | Superoxide | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2013, Volume 305, Issue 12, pp. G911 - G918
Journal Article
Journal Article
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6091, pp. 195 - 199
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 128 - 132
Folates enable the activation and transfer of one-carbon units for the biosynthesis of purines, thymidine and methionine(1-3). Antifolates are important... 
CHAIN | HYPERTROPHIC CARDIOMYOPATHY | SERINE HYDROXYMETHYLTRANSFERASE | METABOLISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DEFECT | LACTIC-ACIDOSIS | MUTATIONS | IDENTIFICATION | ANTICODON WOBBLE NUCLEOTIDE | Mitochondria - enzymology | Electron Transport | Protein Biosynthesis | Humans | Ribosomes - metabolism | Sarcosine - metabolism | Multifunctional Enzymes - metabolism | Thymine Nucleotides - biosynthesis | Oxidative Phosphorylation - drug effects | Glycine Hydroxymethyltransferase - deficiency | HEK293 Cells | RNA, Transfer - genetics | Codon - genetics | RNA, Transfer - chemistry | Leucine - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Biocatalysis | RNA, Transfer - metabolism | HCT116 Cells | Mitochondria - metabolism | Mitochondria - drug effects | Glycine Hydroxymethyltransferase - metabolism | Guanosine - metabolism | Tetrahydrofolates - metabolism | Lysine - genetics | Carrier Proteins - metabolism | Methylation - drug effects | Folic Acid - metabolism | Aminohydrolases - metabolism | Folic Acid Antagonists - pharmacology | GTP-Binding Proteins - metabolism | Mitochondria | Physiological aspects | Genetic aspects | Methylation | Observations | Genetic translation | Folic acid | Transfer RNA | Phosphorylation | Inborn errors of metabolism | Peptides | Serine | Biosynthesis | Mitochondrial DNA | Thymidine | Catalytic activity | Leucine | Cytosol | Experiments | Anticancer properties | Proteins | Purines | Antitumor agents | Metabolites | Lymphocytes | Vitamin B | Catalysis | Enzymes | Translation | tRNA Ala | tRNA | Methionine | Metabolism | Carbon | Immunosuppression | Oxidative phosphorylation | Lysine | Proteomics | Electron transport | Respiration | Codons | Cancer
Journal Article