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1. Full Text The Role of MeCP2 in the Brain
by Guy, Jacky and Cheval, Hélène and Selfridge, Jim and Bird, Adrian
Annual Review of Cell and Developmental Biology, ISSN 1081-0706, 11/2011, Volume 27, Issue 1, pp. 631 - 652
Methyl-CpG binding protein 2 (MeCP2) was first identified in 1992 as a protein that binds specifically to methylated DNA. Mutations in the MECP2 gene were... 
DNA methylation | methyl-CpG binding domain (MBD) | epigenetics | Rett syndrome | Epigenetics | Methyl-CpG binding domain (MBD) | RETT-SYNDROME | DEVELOPMENTAL BIOLOGY | CPG-BINDING PROTEIN-2 | SYNAPTIC PLASTICITY | CEREBRAL-CORTEX | CELL BIOLOGY | CHROMATIN-REMODELING COMPLEX | MOUSE MODEL | GENE-EXPRESSION | METHYL-CPG | TRANSCRIPTIONAL REPRESSOR | Protein Structure, Tertiary | Brain - anatomy & histology | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Repressor Proteins - genetics | Brain - growth & development | Methyl-CpG-Binding Protein 2 - genetics | Brain - metabolism | DNA Methylation | Animals | Methyl-CpG-Binding Protein 2 - chemistry | CpG Islands | Protein Binding | Neuroglia - metabolism | Neurons - metabolism | Repressor Proteins - metabolism | Physiological aspects | Development and progression | Research | Gene mutations | Binding proteins
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2. Full Text A role for glia in the progression of Rett's syndrome
by Lioy, DT and Garg, SK and Monaghan, CE and Raber, J and Foust, KD and Kaspar, BK and Hirrlinger, PG and Kirchhoff, F and Bissonnette, JM and Ballas, N and Mandel, G
NATURE, ISSN 0028-0836, 07/2011, Volume 475, Issue 7357, pp. 497 - U90
Rett's syndrome (RTT) is an X-chromosome-linked autism spectrum disorder caused by loss of function of the transcription factor methyl-CpG-binding protein 2... 
DEFECTS | ABNORMALITIES | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | MICE | NEURONAL MATURATION | RELEASE | MECP2 DEFICIENCY | STRESS | EXPRESSION | ASTROCYTES | Neuroglia - pathology | Vesicular Glutamate Transport Protein 1 - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Methyl-CpG-Binding Protein 2 - metabolism | Male | Motor Activity | Disease Progression | Methyl-CpG-Binding Protein 2 - deficiency | Methyl-CpG-Binding Protein 2 - genetics | Rett Syndrome - physiopathology | Behavior, Animal | Rett Syndrome - metabolism | Animals | Female | Neuroglia - metabolism | Mice | Neurons - metabolism | Rett Syndrome - genetics | Anxiety - metabolism | Astrocytes - metabolism | Development and progression | Genetic aspects | Neuroglia | Abnormalities | Rett syndrome | Studies | Behavior | Anxieties | Rodents | Evacuations & rescues
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3. Full Text miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock
by Alvarez-Saavedra, Matías and Antoun, Ghadi and Yanagiya, Akiko and Oliva-Hernandez, Reynaldo and Cornejo-Palma, Daniel and Perez-Iratxeta, Carolina and Sonenberg, Nahum and Cheng, Hai-Ying M
Human Molecular Genetics, ISSN 0964-6906, 02/2011, Volume 20, Issue 4, pp. 731 - 751
Mammalian circadian rhythms are synchronized to the external time by daily resetting of the suprachiasmatic nucleus (SCN) in response to light. As the master... 
RESPONSE ELEMENT | POLY(A) BINDING-PROTEIN | MESSENGER-RNA | RETT-SYNDROME | SUPRACHIASMATIC NUCLEUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SLEEP PHASE SYNDROME | GENETICS & HEREDITY | GENE-EXPRESSION | POLY(A)-BINDING PROTEIN | HISTONE ACETYLTRANSFERASE | ACTIVE GENES | NIH 3T3 Cells | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Chromatin Assembly and Disassembly - genetics | MicroRNAs - metabolism | E1A-Associated p300 Protein - metabolism | Chromatin Assembly and Disassembly - drug effects | Retinoblastoma-Binding Protein 2 - metabolism | Immediate-Early Proteins - metabolism | Period Circadian Proteins - genetics | Light | HEK293 Cells | Suprachiasmatic Nucleus - metabolism | DNA-Binding Proteins | Tumor Suppressor Proteins - metabolism | Signal Transduction | Mice, Inbred C57BL | Circadian Rhythm - genetics | Computational Biology | Gene Expression Regulation | Mice, Transgenic | RNA Stability | Animals | Period Circadian Proteins - metabolism | Mice | MicroRNAs - genetics | Jumonji Domain-Containing Histone Demethylases | Suprachiasmatic nucleus | Calcium | Transcription | CLOCK protein | BTG2 protein | Period 1 protein | Methyl-CpG binding protein | Entrainment | miRNA | Period 2 protein | Circadian rhythms | Obesity | Translation | mRNA turnover | Cyclic AMP | Light effects | Oscillators | Promoters | Chromatin remodeling | Neurological diseases | Period protein | Sleep | MeCP2 protein | Workers | Pacemakers | Cardiovascular diseases | Cancer
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4. Full Text Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State
by Skene, Peter J and Illingworth, Robert S and Webb, Shaun and Kerr, Alastair R.W and James, Keith D and Turner, Daniel J and Andrews, Rob and Bird, Adrian P
Molecular Cell, ISSN 1097-2765, 02/2010, Volume 37, Issue 4, pp. 457 - 468
MeCP2 is a nuclear protein with an affinity for methylated DNA that can recruit histone deacetylases. Deficiency or excess of MeCP2 causes severe neurological... 
DNA | MOLNEURO | REPEAT LENGTH | RETT-SYNDROME | DNA METHYLATION | PHOSPHORYLATION | BDNF TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | GENES | MICE | CPG-BINDING PROTEIN-2 | TRANSCRIPTIONAL REPRESSOR | CELL BIOLOGY | Chromatin - metabolism | Brain - cytology | Mice, Inbred C57BL | Protein Multimerization | Methyl-CpG-Binding Protein 2 - metabolism | Nucleosomes - metabolism | Neurons - cytology | Methyl-CpG-Binding Protein 2 - deficiency | Mice, Knockout | Brain - metabolism | DNA Methylation | Animals | Cell Nucleus - metabolism | CpG Islands | Protein Binding | Transcription, Genetic | Mice | Neurons - metabolism | Histones - metabolism | Genome | Chromatin | Neurons | Genomics | Brain | Histone deacetylase | Transcription | Data processing | Methyl-CpG binding protein | Repressors | MeCP2 protein | DNA methylation | Acetylation | Glia | Histone H1
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5. Full Text Cross talk between microRNA and epigenetic regulation in adult neurogenesis
by Keith E. Szulwach and Xuekun Li and Richard D. Smrt and Yujing Li and Yuping Luo and Li Lin and Nicholas J. Santistevan and Wendi Li and Xinyu Zhao and Peng Jin
The Journal of Cell Biology, ISSN 0021-9525, 4/2010, Volume 189, Issue 1, pp. 127 - 141
Both microRNAs (miRNAs) and epigenetic regulation have important functions in stem cell biology, although the interactions between these two pathways are not... 
Untranslated regions | Chromatin | MicroRNA | Neurons | DNA | Stem cells | Epigenetics | Neural stem cells | Gene expression regulation | Neurogenesis | MECP2 | DEVELOPMENTAL REGULATORS | RETT-SYNDROME | DNA METHYLATION | HISTONE H3 | EARLY MOUSE DEVELOPMENT | EMBRYONIC STEM-CELLS | GENE-EXPRESSION | SELF-RENEWAL | CPG-BINDING PROTEIN-2 | CELL BIOLOGY | Chromatin - metabolism | Histone-Lysine N-Methyltransferase - genetics | Epigenesis, Genetic | Methyl-CpG-Binding Protein 2 - metabolism | Repressor Proteins - genetics | Mice, Transgenic | MicroRNAs - metabolism | Polycomb-Group Proteins | Stem Cells - metabolism | Enhancer of Zeste Homolog 2 Protein | Methyl-CpG-Binding Protein 2 - genetics | Neurogenesis - genetics | Polycomb Repressive Complex 2 | Animals | Histone-Lysine N-Methyltransferase - metabolism | Mice | MicroRNAs - genetics | Repressor Proteins - metabolism | Histones | Genetic aspects | Properties | Observations | Protein binding
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6. Full Text Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
by Guo, Junjie U and Su, Yijing and Shin, Joo Heon and Shin, Jaehoon and Li, Hongda and Xie, Bin and Zhong, Chun and Hu, Shaohui and Le, Thuc and Fan, Guoping and Zhu, Heng and Chang, Qiang and Gao, Yuan and Ming, Guo-Li and Song, Hongjun
Nature Neuroscience, ISSN 1097-6256, 02/2014, Volume 17, Issue 2, pp. 215 - 222
DNA methylation has critical roles in the nervous system and has been traditionally considered to be restricted to CpG dinucleotides in metazoan genomes. Here... 
NERVOUS-SYSTEM | EPIGENETICS | METHYLTRANSFERASE | BASE-RESOLUTION | EMBRYONIC STEM-CELLS | DNMT3A | MOUSE | PATTERNS | ACTIVE DNA DEMETHYLATION | ENZYMATIC-PROPERTIES | NEUROSCIENCES | Brain - cytology | Epigenomics | Embryo, Mammalian | Gene Expression - genetics | Humans | Mice, Inbred C57BL | Methyl-CpG-Binding Protein 2 - metabolism | Male | Brain - growth & development | CpG Islands - physiology | RNA, Messenger - metabolism | Nerve Tissue Proteins - genetics | Methyl-CpG-Binding Protein 2 - genetics | Brain - metabolism | Nerve Tissue Proteins - metabolism | Animals | Chromatin Immunoprecipitation | Neurons - physiology | Electrophoretic Mobility Shift Assay | Mice | DNA Methylation - physiology | Genome | Genetic aspects | Brain research | Research | Genetic regulation | Brain mapping | Index Medicus
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7. Full Text Disruption of DNA-methylation-dependent long gene repression in Rett syndrome
by Gabel, Harrison W and Kinde, Benyam and Stroud, Hume and Gilbert, Caitlin S and Harmin, David A and Kastan, Nathaniel R and Hemberg, Martin and Ebert, Daniel H and Greenberg, Michael E
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7554, pp. 89 - 93
Disruption of the MECP2 gene leads to Rett syndrome (RTT), a severe neurological disorder with features of autism(1). MECP2 encodes a methyl-DNA-binding... 
MECP2 | MESSENGER-RNAS | CHROMATIN | PHOSPHORYLATION | BDNF TRANSCRIPTION | MULTIDISCIPLINARY SCIENCES | PURIFICATION | BINDING DOMAIN | DUPLICATION | EXPRESSION CHANGES | MOUSE MODELS | Humans | Gene Expression Regulation | Methyl-CpG-Binding Protein 2 - metabolism | Molecular Sequence Data | Male | DNA Methylation - genetics | Mutation - genetics | Methyl-CpG-Binding Protein 2 - deficiency | Methyl-CpG-Binding Protein 2 - genetics | Brain - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | Animals | Base Sequence | Female | Mice | Neurons - metabolism | Rett Syndrome - genetics | Disease Models, Animal | Studies | Brain | Pathology | DNA methylation | Genomes | Mutation | Gene expression | Deoxyribonucleic acid--DNA | Neurological disorders
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8. Full Text Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR
by Ebert, Daniel H and Gabel, Harrison W and Robinson, Nathaniel D and Kastan, Nathaniel R and Hu, Linda S and Cohen, Sonia and Navarro, Adrija J and Lyst, Matthew J and Ekiert, Robert and Bird, Adrian P and Greenberg, Michael E
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7458, pp. 341 - 345
Rett syndrome (RTT) is an X-linked human neurodevelopmental disorder with features of autism and severe neurological dysfunction in females. RTT is caused by... 
INHIBITION | RETT-SYNDROME | REPRESSION | CHROMATIN | BDNF TRANSCRIPTION | MULTIDISCIPLINARY SCIENCES | DISORDER | MUTATIONS | METHYL-CPG | BINDING | ASSOCIATION | Phosphorylation | Humans | Cells, Cultured | Methyl-CpG-Binding Protein 2 - metabolism | Co-Repressor Proteins - metabolism | Threonine - metabolism | Methyl-CpG-Binding Protein 2 - genetics | Animals | Methyl-CpG-Binding Protein 2 - chemistry | Transcription, Genetic | Mice | Neurons - metabolism | Mutation | Rett Syndrome - genetics | Physiological aspects | Research | Binding proteins | Analysis | Rett syndrome | Brain | Brain-derived neurotrophic factor | Kinases | Rodents
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9. Full Text ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain
by Kernohan, Kristin D and Jiang, Yan and Tremblay, Deanna C and Bonvissuto, Anne C and Eubanks, James H and Mann, Mellissa R.W and Bérubé, Nathalie G
Developmental Cell, ISSN 1534-5807, 02/2010, Volume 18, Issue 2, pp. 191 - 202
Human developmental disorders caused by chromatin dysfunction often display overlapping clinical manifestations, such as cognitive deficits, but the underlying... 
DNA | HUMDISEASE | DEVBIO | PROTEIN ATRX | RETT-SYNDROME | MENTAL-RETARDATION | DNA METHYLATION | SNF2 FAMILY | DLK1-GTL2 LOCUS | DE-LANGE-SYNDROME | DEVELOPMENTAL BIOLOGY | H19 GENE | X SYNDROME | HUMAN HOMOLOG | CELL BIOLOGY | Chromatin - metabolism | Genomic Imprinting | Humans | Methyl-CpG-Binding Protein 2 - metabolism | Cognition Disorders - metabolism | Male | X-linked Nuclear Protein | Brain - growth & development | Gene Regulatory Networks | RNA, Untranslated - genetics | Methyl-CpG-Binding Protein 2 - genetics | Brain - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | DNA Methylation | Insulin-Like Growth Factor II - genetics | Nuclear Proteins - deficiency | Cell Cycle Proteins - genetics | Female |