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Cancer Letters, ISSN 0304-3835, 2017, Volume 397, pp. 1 - 11
Abstract The role of histone deacetylase (HDAC) 4 and 6 in glioblastoma (GBM) radioresistance was investigated. We found that tumor samples from 31 GBM... 
Hematology, Oncology and Palliative Medicine | HDAC4 | Radioresistance | Radiotherapy | HDAC6 | Glioblastoma | MALIGNANT GLIOMA-CELLS | AUTOPHAGY | CELLULAR SENESCENCE | CANCER-THERAPY | TEMOZOLOMIDE | P53 | HISTONE DEACETYLASES | ONCOLOGY | IONIZING-RADIATION | INHIBITOR | EXPRESSION | Glioblastoma - enzymology | Apoptosis - radiation effects | Autophagy - radiation effects | Humans | Middle Aged | Brain Neoplasms - pathology | DNA Repair - radiation effects | Male | DNA Breaks, Double-Stranded | Glioblastoma - radiotherapy | Tumor Suppressor Protein p53 - genetics | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | Cellular Senescence - radiation effects | Neoplastic Stem Cells - pathology | Adult | Female | Signal Transduction - radiation effects | Brain Neoplasms - radiotherapy | Repressor Proteins - metabolism | Neoplastic Stem Cells - radiation effects | Brain Neoplasms - enzymology | Histone Deacetylases - genetics | Histone Deacetylase 6 | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | Radiation Tolerance - genetics | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Phenotype | Glioblastoma - pathology | Cell Line, Tumor | Aged | Mutation | Dose-Response Relationship, Radiation | Neoplastic Stem Cells - enzymology | Cell Proliferation - radiation effects | RNA | Cell death | Analysis | DNA | Radiation | Genetic aspects | Information management | Tumor proteins | Glioblastoma multiforme | Biotechnology | Cell culture | Senescence | Brain cancer | p53 Protein | Radiation therapy | Gene expression | Kinases | Cancer therapies | Autophagy | Proteins | Plasmids | Rodents | Stem cells | DNA methylation | Epigenetics | Protein expression | Deoxyribonucleic acid--DNA | Apoptosis | Tumors
Journal Article
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