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Biochemical Pharmacology, ISSN 0006-2952, 10/2016, Volume 118, pp. 109 - 120
[Display omitted] Mercury compounds are well-known toxic environmental pollutants and potently induce severe neurotoxicological effects in human and... 
Neurotoxicity | Arginine decarboxylase | Inhibition | Molecular dynamics simulation | Mercury | NERVOUS-SYSTEM | AGMATINE | OXIDATIVE STRESS | CHROMATOGRAPHY | RAT HIPPOCAMPAL-NEURONS | METHYLMERCURY NEUROTOXICITY | GLUTAMATE | PHARMACOLOGY & PHARMACY | HEALTH | EXPOSURE | BRAIN | Gene Expression Regulation, Enzymologic - drug effects | Coordination Complexes - antagonists & inhibitors | Carboxy-Lyases - antagonists & inhibitors | Mercuric Chloride - metabolism | Methylmercury Compounds - metabolism | Absorption, Physiological | Agmatine - metabolism | Coordination Complexes - metabolism | Environmental Pollutants - metabolism | Carboxy-Lyases - genetics | Decarboxylation - drug effects | Ethylmercuric Chloride - toxicity | Nerve Tissue Proteins - chemistry | Biocatalysis - drug effects | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Environmental Pollutants - antagonists & inhibitors | Carboxy-Lyases - metabolism | Neurons - metabolism | Environmental Pollutants - toxicity | Neurons - drug effects | Binding Sites | Cell Survival - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Phenylmercury Compounds - toxicity | Enzyme Inhibitors - metabolism | Ethylmercuric Chloride - metabolism | Methylmercury Compounds - antagonists & inhibitors | Models, Molecular | Phenylmercury Compounds - metabolism | Rats | Carboxy-Lyases - chemistry | Coordination Complexes - chemistry | Nerve Tissue Proteins - genetics | Phenylmercury Compounds - antagonists & inhibitors | Molecular Dynamics Simulation | Ethylmercuric Chloride - antagonists & inhibitors | Nerve Tissue Proteins - metabolism | Animals | Mercuric Chloride - antagonists & inhibitors | Neurons - enzymology | Agmatine - antagonists & inhibitors | Methylmercury Compounds - toxicity | Cell Line, Tumor | Mercuric Chloride - toxicity | Arginine - metabolism | Arginine | Environmental aspects | Mercury compounds | Index Medicus
Journal Article
The FASEB Journal, ISSN 0892-6638, 01/2011, Volume 25, Issue 1, pp. 370 - 381
Mercury toxicity is a highly interesting topic in biomedicine due to the severe endpoints and treatment limitations. Selenite serves as an antagonist of... 
thioredoxin system | antidotes | mercury toxicity | selenium | selenoproteins | Mercury toxicity | Antidotes | Selenium | Selenoproteins | Thioredoxin system | ACID | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | METABOLISM | GLUTATHIONE | METHYLMERCURY | LIVER | PURIFICATION | BIOLOGY | INORGANIC MERCURY | TOXICOLOGY | HEALTH | Selenocysteine - metabolism | Mercuric Chloride - metabolism | Methylmercury Compounds - metabolism | Thioredoxin-Disulfide Reductase - genetics | Humans | NADP - pharmacology | Mercury - metabolism | Dose-Response Relationship, Drug | Sodium Selenite - metabolism | Glutathione - pharmacology | Spectrometry, Mass, Electrospray Ionization | Thioredoxin-Disulfide Reductase - metabolism | Biocatalysis - drug effects | HEK293 Cells | Mercury - antagonists & inhibitors | Cysteine - metabolism | Molecular Structure | Mercury - pharmacology | Mercury Poisoning - prevention & control | Recombinant Proteins - metabolism | Cell Survival - drug effects | Catalytic Domain | Recombinant Proteins - antagonists & inhibitors | Methylmercury Compounds - antagonists & inhibitors | Chelating Agents - chemistry | Rats | Selenium Compounds - metabolism | Mercuric Chloride - pharmacology | Sodium Selenite - pharmacology | Chelating Agents - pharmacology | Enzyme Activation - drug effects | Animals | Mercuric Chloride - antagonists & inhibitors | Thioredoxin-Disulfide Reductase - antagonists & inhibitors | Mercury Compounds - metabolism | Methylmercury Compounds - pharmacology
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2011, Volume 251, Issue 2, pp. 95 - 103
Mercury compounds were recently found to interact in vitro with the thioredoxin system, inhibiting both Thioredoxin (Trx) and Thioredoxin reductase (TrxR). In... 
Fish | Thioredoxin | Mercury | Thioredoxin reductase | Methylmercury | RAT | SELENIUM | MERCURY EXPOSURE | METHYL MERCURY | METABOLISM | GLUTATHIONE | REDUCTASE | PHARMACOLOGY & PHARMACY | INORGANIC MERCURY | TOXICOLOGY | ACCUMULATION | Methylmercury Compounds - metabolism | Liver - metabolism | Protein Transport - physiology | Protein Transport - drug effects | Brain - drug effects | Brain - metabolism | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | Liver - drug effects | Thioredoxin-Disulfide Reductase - metabolism | Methylmercury Compounds - toxicity | Thioredoxins - metabolism | Thioredoxin-Disulfide Reductase - antagonists & inhibitors | Thioredoxins - antagonists & inhibitors | Sea Bream - metabolism | Superoxide | Thiols | Liver | Index Medicus | Brain | Enzymes | Complementarity | Thioredoxin-disulfide reductase | Organs | Muscles | Dimethylmercury | Kidney | Toxicants | glutathione reductase | Depuration | AQUATIC ORGANISMS | SUPEROXIDE DISMUTASE | DIGESTIVE SYSTEM | NERVOUS SYSTEM | 60 APPLIED LIFE SCIENCES | KIDNEYS | THIOLS | ELEMENTS | MERCURY | INHIBITION | GLANDS | METALS | IN VITRO | ENZYMES | DRUGS | ORGANIC SULFUR COMPOUNDS | FISHES | VERTEBRATES | RADIOPROTECTIVE SUBSTANCES | BRAIN | ANIMALS | MERCURY COMPOUNDS | RESPONSE MODIFYING FACTORS | ORGANIC COMPOUNDS | JUVENILES | CENTRAL NERVOUS SYSTEM | IN VIVO | POLYPEPTIDES | ORGANS | PEPTIDES | METHYLMERCURY | LIVER | ORGANIC MERCURY COMPOUNDS | PROTEINS | BODY | MUSCLES | CONTROL | OXIDOREDUCTASES
Journal Article
Neurotoxicology, ISSN 0161-813X, 09/2013, Volume 38, pp. 1 - 8
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2012, Volume 52, Issue 4, pp. 781 - 793
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 554 - 563
Journal Article
Journal of Applied Toxicology, ISSN 0260-437X, 09/2017, Volume 37, Issue 9, pp. 1073 - 1081
Journal Article