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Biochemical Pharmacology, ISSN 0006-2952, 2007, Volume 73, Issue 4, pp. 550 - 560
Journal Article
Oncogene, ISSN 0950-9232, 01/2007, Volume 26, Issue 2, pp. 186 - 197
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 01/2005, Volume 79, Issue 1‐2, pp. 216 - 223
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Journal of Biological Chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 52, pp. 40461 - 40471
Journal Article
by S Aebi and D Fink and R Gordon and H K Kim and H Zheng and J L Fink and S B Howell
Clinical Cancer Research, ISSN 1078-0432, 10/1997, Volume 3, Issue 10, pp. 1763 - 1767
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2007, Volume 573, Issue 1, pp. 241 - 248
The nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) which was initially known for its role in the repair of oxidative stress-induced DNA damage, has also... 
Poly(ADP-ribose) polymerase-1 | NF-κB | Inflammation | IL-8 | Flavone | POLY(ADP-RIBOSE) POLYMERASE | TRANSCRIPTIONAL ACTIVATION | OXIDATIVE-STRESS | DNA-BINDING | poly(ADP-ribose) polymerase-1 | INTERLEUKIN-8 | ADP-RIBOSE POLYMERASE-1 | NF-kappa B | inflammation | INDUCED SPUTUM | A549 CELLS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | flavone | IEL-8 | LUNG INFLAMMATION | Interleukin-8 - genetics | Transcription, Genetic - drug effects | Spin Trapping - methods | Antioxidants - chemistry | Flavones | Antioxidants - metabolism | Humans | NF-kappa B - metabolism | Dose-Response Relationship, Drug | Methylnitronitrosoguanidine - pharmacology | Cell Nucleus - metabolism | Ferrous Compounds - pharmacology | Alcohol Oxidoreductases - antagonists & inhibitors | Cyclic N-Oxides - metabolism | Benzamides - pharmacology | Flavonoids - pharmacology | Molecular Structure | Interleukin-8 - metabolism | NAD - metabolism | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Alcohol Oxidoreductases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Poly(ADP-ribose) Polymerase Inhibitors | Hydrogen Peroxide - metabolism | Gene Expression Regulation - drug effects | Phenanthrenes - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | NF-kappa B - genetics | Ferrous Compounds - metabolism | Lipopolysaccharides - pharmacology | Nucleotidases - pharmacology | Cell Line, Tumor | Poly (ADP-Ribose) Polymerase-1 | Cell Nucleus - drug effects | Flavonoids - chemistry
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10209 - 10214
Journal Article
Nature Genetics, ISSN 1061-4036, 03/1999, Volume 21, Issue 3, pp. 326 - 329
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 10/2005, Volume 32, Issue 10, pp. 888 - 893
SUMMARY 1. Tumors arise and progress through the accumulation of serial genetic changes, including successive mutations, which involve activation of... 
antimutagenic | anti-oxidant | chemoprevention | celecoxib | anti‐oxidant | Antimutagenic | Celecoxib | Anti-oxidant | Chemoprevention | ONCOGENES | PHYSIOLOGY | RAS | SC-58635 | MODEL | CANCER | FREE-RADICALS | CARCINOGENESIS | INFLAMMATION | PHARMACOLOGY & PHARMACY | PROGRESSION | 9,10-Dimethyl-1,2-benzanthracene - toxicity | Free Radical Scavengers - pharmacology | Mutagens - toxicity | Sodium Azide - toxicity | Microsomes, Liver - metabolism | Male | Antimutagenic Agents - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Methylnitronitrosoguanidine - toxicity | Microsomes, Liver - drug effects | Lipid Peroxidation - drug effects | Superoxides - metabolism | Salmonella typhimurium - drug effects | Pyrazoles - pharmacology | 2-Acetylaminofluorene - toxicity | Salmonella typhimurium - genetics | Rats | Antioxidants - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Doxorubicin - toxicity | Animals | Mutation - drug effects | Phenylenediamines - toxicity | 9,10-Dimethyl-1,2-benzanthracene, toxicity | Lipid Peroxidation, drug effects | Mutagens, toxicity | Antimutagenic Agents, pharmacology | Mutation, drug effects | Doxorubicin, toxicity | Salmonella typhimurium, drug effects | Anti-Inflammatory Agents, Non-Steroidal, pharmacology | Methylnitronitrosoguanidine, toxicity | Microsomes, Liver, drug effects | Phenylenediamines, toxicity | 2-Acetylaminofluorene, toxicity | Antioxidants, pharmacology | Pyrazoles, pharmacology | Sodium Azide, toxicity | Superoxides, metabolism | Free Radical Scavengers, pharmacology | Sulfonamides, pharmacology
Journal Article
Journal Article
Science, ISSN 0036-8075, 7/2002, Volume 297, Issue 5579, pp. 259 - 263
Poly(ADP-ribose) polymerase-1 (PARP-1) protects the genome by functioning in the DNA damage surveillance network. PARP-1 is also a mediator of cell death after... 
Mitochondria | Delta cells | Cell death | B lymphocytes | Cell nucleus | DNA damage | Mitochondrial membranes | Fibroblasts | Antibodies | Reports | Condensation | MITOCHONDRIAL PERMEABILITY TRANSITION | ACTIVATION | GENOMIC STABILITY | INHIBITION | MULTIDISCIPLINARY SCIENCES | GENE DISRUPTION | POLYMERASE | SYNTHETASE | REPERFUSION | PARP | NEUROTOXICITY | Oxidative Stress | Apoptosis Inducing Factor | Receptors, N-Methyl-D-Aspartate - metabolism | Neurons - cytology | N-Methylaspartate - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Methylnitronitrosoguanidine - pharmacology | Caspases - metabolism | Cell Nucleus - metabolism | Neurons - physiology | Antibodies - immunology | Membrane Proteins - metabolism | Active Transport, Cell Nucleus | NAD - metabolism | Flavoproteins - metabolism | N-Methylaspartate - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Membrane Proteins - immunology | Mitochondria - metabolism | Caspase Inhibitors | Poly(ADP-ribose) Polymerase Inhibitors | Cytochrome c Group - metabolism | Mice, Knockout | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Membrane Potentials | Flavoproteins - immunology | Mice | Enzyme Activation | Mitochondria - physiology | Apoptosis | Research | Enzymes | Cellular biology | Deoxyribonucleic acid | DNA | Injuries
Journal Article