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IUBMB Life, ISSN 1521-6543, 12/2009, Volume 61, Issue 12, pp. 1132 - 1142
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 04/2019, Volume 62, Issue 7, pp. 3286 - 3296
Bacterial 5'-methylthioadenosine/S-adenosyl-homocysteine nucleosidase (MTAN) hydrolyzes adenine from its substrates to form S-methyl-5-thioribose and... 
MTAN | ANGSTROM RESOLUTION | ADENOSYLHOMOCYSTEINE | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE | CHEMISTRY, MEDICINAL | ENZYME | PATHWAY | 5'-METHYLTHIOADENOSINE NUCLEOSIDASE | ESCHERICHIA-COLI | TRANSITION-STATE ANALOG | BINDING
Journal Article
Journal of Structural Biology, ISSN 1047-8477, 2011, Volume 173, Issue 1, pp. 86 - 98
5′-Methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN) plays a key role in the methionine-recycling pathway of bacteria and plants.... 
Isothermal titration calorimetry | 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidase | Dynamics | Substrate specificity | Deuterium–hydrogen exchange coupled mass spectrometry | Deuterium-hydrogen exchange coupled mass spectrometry | 5'-Methylthioadenosine/S-adenosylhomocysteine nucleosidase | 5 '-Methylthioadenosine/S-adenosylhomocysteine nucleosidase | ETHYLENE SYNTHESIS | ARABIDOPSIS-THALIANA | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXCHANGE-MASS-SPECTROMETRY | X-RAY-DIFFRACTION | PHOSPHOLIPASE A | CELL BIOLOGY | CONFORMATIONAL-CHANGES | BIOPHYSICS | AMIDE HYDROGEN/DEUTERIUM EXCHANGE | 5'-METHYLTHIOADENOSINE NUCLEOSIDASE | QUORUM-SENSING SIGNAL | HYDROGEN-DEUTERIUM EXCHANGE | S-Adenosylhomocysteine - metabolism | Arabidopsis Proteins - genetics | Crystallization | Models, Molecular | Substrate Specificity | Escherichia coli Proteins - metabolism | Binding Sites - genetics | Deoxyadenosines - metabolism | N-Glycosyl Hydrolases - genetics | Purine-Nucleoside Phosphorylase - genetics | N-Glycosyl Hydrolases - metabolism | Arabidopsis Proteins - metabolism | Hydrolysis | Thermodynamics | Escherichia coli Proteins - genetics | Calorimetry | Protein Conformation | Molecular Structure | Catalysis | Thionucleosides - metabolism | Purine-Nucleoside Phosphorylase - metabolism | Arabidopsis thaliana | Purines | Enzymes | Children's hospitals | Escherichia coli | Universities and colleges | Mass spectrometry | S-adenosylhomocysteine nucleosidase | 5′-Methylthioadenosine | mass spectrometry | Deuterium–hydrogen exchange coupled
Journal Article
by Jing, W and Zhu, H and Liu, WJ and Zhai, XY and Tian, HR and Yu, JM
SCIENTIFIC REPORTS, ISSN 2045-2322, 01/2020, Volume 10, Issue 1, pp. 843 - 8
To investigate the predictive value of methylthioadenosine phosphorylase (MTAP) on treatment response and survival in advanced lung adenocarcinoma. MTAP... 
CELLS | FREQUENT | MARKER | METHYLTHIOADENOSINE PHOSPHORYLASE MTAP | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | CANCER STATISTICS | HOMOZYGOUS DELETIONS | EXPRESSION | Immunohistochemistry | Adenocarcinoma | Chemotherapy | 5'-Methylthioadenosine phosphorylase | Platinum | Thorax | Multivariate analysis | Survival | Disease control | Phosphorylase | Bevacizumab | Metastases
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 04/2008, Volume 378, Issue 1, pp. 112 - 128
5′-Methylthioadenosine (MTA)/S-adenosylhomocysteine (SAH) nucleosidase (MTAN) is essential for cellular metabolism and development in many bacterial species.... 
methionine recycling | 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase | S-adenosylhomocysteine | conformational flexibility | 5′-methylthioadenosine | ETHYLENE SYNTHESIS | MACROMOLECULAR STRUCTURES | PROTEIN | 5'-methylthioadenosine | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | COLI 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE | S-ADENOSYLMETHIONINE | TRANSITION-STATE STRUCTURE | XANTHINE-OXIDASE | 5'-METHYLTHIOADENOSINE NUCLEOSIDASE | METHIONINE | Amino Acid Sequence | Arabidopsis Proteins - genetics | Deoxyadenosines - chemistry | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Purine-Nucleoside Phosphorylase - genetics | Hydrolysis | Arabidopsis Proteins - chemistry | Protein Conformation | Purine-Nucleoside Phosphorylase - chemistry | Catalysis | Kinetics | Binding Sites | Thionucleosides - chemistry | Physiological aspects | Analysis | Phosphorylase | Methionine | ESCHERICHIA COLI | SPECIFICITY | BASIC BIOLOGICAL SCIENCES | SUBSTRATES | FLEXIBILITY | RESOLUTION | national synchrotron light source | STREPTOCOCCUS | METABOLISM | AFFINITY | AMINO ACIDS | ENZYMES | KINETICS | GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE | PHOSPHOTRANSFERASES | ARABIDOPSIS | EFFICIENCY | RESIDUES | S-adenosylhomocysteine nucleosidase
Journal Article
The Plant Journal, ISSN 0960-7412, 06/2010, Volume 62, Issue 6, pp. 977 - 988
Journal Article
Analytical Chemistry, ISSN 0003-2700, 12/2016, Volume 88, Issue 23, pp. 11860 - 11867
5′-Methylthioadenosine phosphorylase (MTAP) and 5′-methylthioadenosine nucleosidase (MTAN) catalyze the phosphorolysis and hydrolysis of 5′-methylthioadenosine... 
METHYLTHIOADENOSINE PHOSPHORYLASE | CHEMISTRY, ANALYTICAL | ENZYME | PATHWAY | 5'-METHYLTHIOADENOSINE NUCLEOSIDASE | HELICOBACTER | INHIBITORS | TRANSITION-STATE ANALOG | BINDING | Adenosine | Chemical properties | Research | Chemical reaction, Rate of | Phosphorylase | Methyl groups
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 11/2018, Volume 13, Issue 11, pp. 3173 - 3183
Campylobacter jejuni is a Gram-negative bacterium responsible for food-borne gastroenteritis and associated with Guillain-Barré, Reiter, and irritable bowel... 
5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE | ENZYME | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | RESISTANCE | METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE | HELICOBACTER | INHIBITORS | SIMILARITY | PHOSPHORYLASE
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2005, Volume 352, Issue 3, pp. 559 - 574
MTA/AdoHcy nucleosidase (MTAN) irreversibly hydrolyzes the N9-C1′ bond in the nucleosides, 5′-methylthioadenosine (MTA) and S-adenosylhomocysteine (AdoHcy) to... 
reaction coordinate | S-adenosylhomocysteine | conformational flexibility | 5′-methylthioadenosine | 5′-methylthioadenosine/ S-adenosylhomocysteine nucleosidase | 5′-methylthioadenosine/S- adenosylhomocysteine nucleosidase | Conformational flexibility | Reaction coordinate | 5 '-methylthioadenosine | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | COMPLEXES | TRANSITION-STATE | COLI 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE | PHOSPHORYLASE | ANGSTROM RESOLUTION | SUBSTRATE-BINDING | 5 '-methylthioadenosine/S-adenosylhomocysteine nucleosidase | INHIBITOR | QUORUM-SENSING SIGNAL | METHIONINE | Escherichia coli - enzymology | Mutagenesis, Site-Directed | Models, Molecular | Crystallography, X-Ray | N-Glycosyl Hydrolases - genetics | Purine-Nucleoside Phosphorylase - genetics | Static Electricity | N-Glycosyl Hydrolases - chemistry | N-Glycosyl Hydrolases - metabolism | Hydrogen Bonding | Escherichia coli - genetics | Protein Conformation | Purine-Nucleoside Phosphorylase - chemistry | Catalysis | Purine-Nucleoside Phosphorylase - metabolism | Binding Sites | Amino Acid Substitution | Enzymes | Biological products | Children's hospitals | Methionine | Crystals | Glycerol | Adenine | Polyamines | Air defenses | Glycerin | Antiairborne warfare | Enzyme inhibitors | Analysis | Physiological aspects | Nucleosides | Universities and colleges | Methylation | Structure
Journal Article