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Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 2862 - 2870
Neuronal activity evokes localized changes in blood flow. Although this response, termed neurovascular coupling, is widely used to monitor human brain function... 
Arachidonic acid metabolites | Retina | Calcium | Glia | ATP | Blood flow | arachidonic acid metabolites | NEURONAL-ACTIVITY | 20-HETE | calcium | RAT | ASTROCYTE-MEDIATED CONTROL | CALCIUM WAVES | ARACHIDONIC-ACID | glia | NEUROSCIENCES | HEMODYNAMIC-RESPONSE | retina | NITRIC-OXIDE | blood flow | MULLER CELLS | BRAIN | Arterioles - physiology | Cytochrome P-450 Enzyme Inhibitors | Rats, Long-Evans | Arterioles - enzymology | Nitric Oxide Synthase - physiology | Male | Vasodilation - radiation effects | Retinal Vessels - enzymology | Retinal Vessels - physiology | Hydroxyeicosatetraenoic Acids - biosynthesis | Vasoconstriction - radiation effects | Photolysis | Cyclic N-Oxides - pharmacology | Inositol 1,4,5-Trisphosphate - analogs & derivatives | Eye Proteins - antagonists & inhibitors | Purinergic Antagonists | Signal Transduction - radiation effects | Cytochrome P-450 Enzyme System - physiology | Hydrazines - pharmacology | Rats | Imidazoles - pharmacology | Retinal Vessels - drug effects | Arterioles - drug effects | Vasoconstriction - drug effects | Cytochrome P-450 CYP4A - physiology | Signal Transduction - drug effects | Miconazole - pharmacology | Eye Proteins - physiology | Retinal Vessels - radiation effects | Vasodilation - drug effects | Arterioles - radiation effects | Nitric Oxide - pharmacology | Caproates - pharmacology | Vasomotor System - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Inositol 1,4,5-Trisphosphate - pharmacology | Adenosine Triphosphate - pharmacology | Vasoconstriction - physiology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Proadifen - pharmacology | Nitric Oxide Donors - pharmacology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Calcium Signaling - radiation effects | Cytochrome P-450 CYP4A - antagonists & inhibitors | Neuroglia - physiology | Nitric Oxide - physiology | Vasomotor System - radiation effects | Animals | Vasomotor System - physiology | Amidines - pharmacology | In Vitro Techniques
Journal Article
British dental journal, ISSN 0007-0610, 11/2018, Volume 225, Issue 10, pp. 907 - 907
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2001, Volume 134, Issue 5, pp. 1003 - 1012
The effects of the endocannabinoid, anandamide, and its metabolically stable analogue, methanandamide, on induced tone were examined in sheep coronary artery... 
endothelium | sheep coronary arteries | arachidonic acid metabolites, K+ channels | relaxation | Anandamide | Arachidonic acid metabolites | Relaxation | Sheep coronary arteries | Endothelium | arachidonic acid metabolites | CELLS | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENSORY NERVES MEDIATE | CANNABINOID RECEPTORS | ISOLATED MESENTERIC-ARTERY | HYPERPOLARIZING FACTOR | VASORELAXANT | VANILLOID RECEPTORS | K+ channels | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | anandamide | TRANSPORT INHIBITOR | Tetraethylammonium - pharmacology | Arachidonic Acid - metabolism | Cytochrome P-450 Enzyme Inhibitors | Capsaicin - pharmacology | Potassium Channels - physiology | Nitric Oxide Synthase - antagonists & inhibitors | Apamin - pharmacology | Cannabinoid Receptor Modulators | Endothelium, Vascular - physiology | Dose-Response Relationship, Drug | Polyunsaturated Alkamides | Glyburide - pharmacology | Piperidines - pharmacology | Phenylmethylsulfonyl Fluoride - pharmacology | Potassium Channel Blockers | 4-Aminopyridine - pharmacology | Endocannabinoids | Pyrazoles - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Coronary Vessels - drug effects | Coronary Vessels - physiology | Enzyme Inhibitors - pharmacology | Capsaicin - analogs & derivatives | Fatty Acids, Unsaturated - pharmacology | Barium - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Arachidonic Acids - pharmacology | Indomethacin - pharmacology | Cannabinoids - pharmacology | Peptides - pharmacology | Animals | Miconazole - pharmacology | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Sheep | Vasodilation - drug effects | In Vitro Techniques | Receptors, Drug - antagonists & inhibitors | Papers
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2007, Volume 27, Issue 12, pp. 2612 - 2618
OBJECTIVE—An initial step in endothelium-derived hyperpolarizing factor-mediated responses is endothelial cell hyperpolarization. Here we address the... 
Protein kinase A | Caveolae | Cytochrome P450 | Endothelium-derived hyperpolarizing factor | ACTIVATION | ENTRY | KINASE | RELAXATION | cytochrome P450 | endothelium-derived hyperpolarizing factor | CORONARY-ARTERIES | SYNTHASE | SOLUBLE EPOXIDE HYDROLASE | PERIPHERAL VASCULAR DISEASE | INHIBITORS | protein kinase A | HEMATOLOGY | BINDING | caveolae | BRADYKININ | TRPC Cation Channels - drug effects | Cytochrome P-450 Enzyme Inhibitors | Humans | Cytochrome P-450 Enzyme System - metabolism | Apamin - pharmacology | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Transfection | Cyclic AMP - analogs & derivatives | Time Factors | Charybdotoxin - pharmacology | Membrane Transport Modulators - pharmacology | Vasodilator Agents - metabolism | Cell Membrane - metabolism | 8,11,14-Eicosatrienoic Acid - pharmacology | Biological Factors - metabolism | Eicosanoic Acids - antagonists & inhibitors | TRPC Cation Channels - genetics | Cyclic AMP - metabolism | Adamantane - analogs & derivatives | Cyclic AMP-Dependent Protein Kinases - metabolism | Adamantane - pharmacology | Bradykinin - metabolism | Endothelial Cells - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Thionucleotides - pharmacology | Protein Transport | Caveolin 1 - metabolism | Cyclic AMP - pharmacology | Cyclic AMP - antagonists & inhibitors | Membrane Potentials | Ruthenium Red - pharmacology | Calcium Signaling - drug effects | Eicosanoic Acids - metabolism | Miconazole - pharmacology | TRPC Cation Channels - metabolism | Cytochrome P-450 Enzyme System - genetics | Epoxide Hydrolases - metabolism | Endothelial Cells - enzymology | Epoxide Hydrolases - antagonists & inhibitors | Endothelial Cells - drug effects
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2007, Volume 35, Issue 11, pp. 2119 - 2126
Predicting drug-drug interactions requires an assessment of the drug concentration available to the enzyme active site, both in vivo, and within an in vitro... 
Tolbutamide - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 CYP3A | Microsomes, Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Fluconazole - metabolism | Quinine - pharmacology | Microsomes, Liver - enzymology | Tolbutamide - metabolism | Fluoxetine - pharmacology | Dextromethorphan - pharmacology | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Fluvoxamine - pharmacokinetics | Ketoconazole - pharmacokinetics | Rats | Rats, Sprague-Dawley | Catalysis - drug effects | Miconazole - pharmacokinetics | Miconazole - pharmacology | Fluoxetine - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Kinetics | Midazolam - pharmacology | Hepatocytes - enzymology | Cytochrome P-450 CYP2D6 Inhibitors | Quinine - pharmacokinetics | Fluconazole - pharmacology | Tolbutamide - pharmacokinetics | Fluoxetine - pharmacokinetics | Ketoconazole - metabolism | Hepatocytes - metabolism | Ketoconazole - pharmacology | Hepatocytes - cytology | Enzyme Inhibitors - pharmacokinetics | Phenytoin - pharmacology | Dextromethorphan - pharmacokinetics | Phenytoin - metabolism | Quinine - metabolism | Fluvoxamine - metabolism | Cells, Cultured | Midazolam - pharmacokinetics | Fluvoxamine - pharmacology | Miconazole - metabolism | Fluconazole - pharmacokinetics | Animals | Midazolam - metabolism | Phenytoin - pharmacokinetics
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2008, Volume 294, Issue 5, pp. 2363 - 2370
The perivascular sensory nerve (PvN) Ca2+-sensing receptor (CaR) is implicated in Ca2+-induced relaxation of isolated, phenylephrine (PE)-contracted mesenteric... 
Arachidonic acid | Vasorelaxation | sensing receptor | arachidonic acid | BKCA CHANNELS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | NERVE CA2+ RECEPTOR | DIETARY CALCIUM | BLOOD-PRESSURE REGULATION | Ca2+-sensing receptor | CORONARY-ARTERIES | SPONTANEOUSLY HYPERTENSIVE RATS | SMOOTH-MUSCLE | vasorelaxation | ARACHIDONIC-ACID MONOOXYGENASES | IN-VIVO | PERIPHERAL VASCULAR DISEASE | HYPERPOLARIZING FACTORS | Lipoprotein Lipase - antagonists & inhibitors | Cytochrome P-450 Enzyme Inhibitors | Rats, Wistar | Calcium - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Mesenteric Arteries - drug effects | 8,11,14-Eicosatrienoic Acid - metabolism | Receptors, Calcium-Sensing - metabolism | Vasodilation | Dose-Response Relationship, Drug | Arachidonic Acids - metabolism | Quinacrine - pharmacology | Phenylephrine - pharmacology | Piperidines - pharmacology | Potassium Channels, Calcium-Activated - metabolism | Lipoprotein Lipase - metabolism | Phospholipase A2 Inhibitors | Endocannabinoids | Potassium Channel Blockers - pharmacology | Pyrazoles - pharmacology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Phospholipases A2 - metabolism | Glycerides - metabolism | Mesenteric Arteries - metabolism | Arachidonic Acids - pharmacology | Peptides - pharmacology | Receptor, Cannabinoid, CB1 - metabolism | Animals | Signal Transduction - drug effects | Miconazole - pharmacology | Potassium Channels, Calcium-Activated - antagonists & inhibitors | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Mesenteric Arteries - enzymology
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2011, Volume 55, Issue 10, pp. 4834 - 4843
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
CDR1P | CURCUMIN-I | FUNGI | INDUCED APOPTOSIS | ANTIFUNGALS | TRIGGERS | HUMAN PATHOGENIC YEAST | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | MECHANISMS | FLUCONAZOLE RESISTANCE | PROTEINS | Farnesol - metabolism | Fluconazole - pharmacology | Reactive Oxygen Species - metabolism | Saccharomyces cerevisiae - genetics | Farnesol - pharmacology | Saccharomyces cerevisiae - drug effects | Fungal Proteins - antagonists & inhibitors | Candida albicans - metabolism | Rhodamines - metabolism | Ketoconazole - pharmacology | Microbial Sensitivity Tests | Saccharomyces cerevisiae - metabolism | Candida albicans - drug effects | Antifungal Agents - metabolism | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Antifungal Agents - pharmacology | Quorum Sensing | Biological Transport, Active - drug effects | Drug Resistance, Multiple, Fungal | Amphotericin B - pharmacology | Drug Synergism | Miconazole - pharmacology | Kinetics | ATP-Binding Cassette Transporters - antagonists & inhibitors | Apoptosis | Fungal Proteins - metabolism | Index Medicus | Drugs | Reactive oxygen species | quorum sensing | Ketoconazole | Multidrug resistance | Adenosinetriphosphatase | Clinical isolates | Data processing | Drug resistance | Synergism | Antioxidants | fluconazole | rhodamine 6G | Farnesol | Miconazole | ATP | Mechanisms of Resistance
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2014, Volume 444, Issue 2, pp. 212 - 217
Microglia are immune cells that maintain brain homeostasis at a resting state by surveying the environment and engulfing debris. However, in some pathological... 
TRP channel | Ca2+ dynamics | MAPK | Nitric oxide | LPS | Microglia | dynamics | ACTIVATION | LTRPC2 | INTRACELLULAR CALCIUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTES | POTENTIAL MELASTATIN 2 | ADP-RIBOSE | NEUROTOXICITY | CELL-DEATH | BIOPHYSICS | TEMPERATURE | LIPOPOLYSACCHARIDE | Microglia - metabolism | Calcium - metabolism | NADPH Oxidases - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Focal Adhesion Kinase 2 - antagonists & inhibitors | Focal Adhesion Kinase 2 - metabolism | Egtazic Acid - analogs & derivatives | Nitriles | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide - biosynthesis | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Microglia - drug effects | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Tyrphostins - pharmacology | Chelating Agents - pharmacology | Blotting, Western | Mice, Knockout | Animals | Egtazic Acid - pharmacology | MAP Kinase Signaling System - drug effects | TRPM Cation Channels - antagonists & inhibitors | Miconazole - pharmacology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Lipopolysaccharides - pharmacology | TRPM Cation Channels - genetics | Mice | TRPM Cation Channels - metabolism | Interferon-gamma - pharmacology | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 01/2018, Volume 159, Issue 1, pp. 217 - 226
Angiotensin II (Ang II) and adrenocorticotropic hormone (ACTH) regulate adrenal vascular tone in vitro through endothelial and zona glomerulosa cell-derived... 
IMIDAZOLE DERIVATIVES | CORTICAL ARTERIES | ENDOCRINOLOGY & METABOLISM | STIMULATE ALDOSTERONE RELEASE | ARACHIDONIC-ACID | SECRETION | EPOXYEICOSATRIENOIC ACIDS | CORONARY-ARTERIES | ENDOTHELIAL NITRIC-OXIDE | ZONA GLOMERULOSA CELLS | ADRENOCORTICOTROPIC HORMONE | Injections, Intravenous | Angiotensin II - administration & dosage | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Adrenocorticotropic Hormone - administration & dosage | Endothelium, Vascular - enzymology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Receptors, Corticotropin - metabolism | Regional Blood Flow - drug effects | 8,11,14-Eicosatrienoic Acid - pharmacology | Adrenal Glands - drug effects | Adrenocorticotropic Hormone - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Receptor, Angiotensin, Type 2 - agonists | Angiotensin II - metabolism | Nitric Oxide - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Adrenal Glands - blood supply | Eicosanoids - antagonists & inhibitors | Receptors, Corticotropin - agonists | Eicosanoids - blood | Rats, Sprague-Dawley | Indomethacin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Animals | Receptor, Angiotensin, Type 2 - metabolism | Adrenal Glands - metabolism | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Eicosanoids - metabolism | Miconazole - pharmacology | Nitric Oxide Synthase - metabolism | Nitric Oxide - metabolism | Cytochrome | Adrenal glands | Menopause | Aldosterone | Blood | Arginine | Blood pressure | Adrenal gland | Miconazole | Angiotensin II | Cytochromes P450 | Cytochrome P450 | Ablation | Cholesterol | Blood flow | NG-Nitroarginine methyl ester | Adrenocorticotropic hormone | Inhibitors | Acids | Perfusion | Nitric oxide | Angiotensin | Steroidogenesis | Indomethacin | Mercury
Journal Article