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Molecular Cell, ISSN 1097-2765, 07/2010, Volume 39, Issue 1, pp. 133 - 144
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2011, Volume 31, Issue 1, pp. 172 - 183
Phosphodiesterase-4 (PDE4) plays an important role in mediating memory via the control of intracellular cAMP signaling; inhibition of PDE4 enhances memory.... 
LONG-TERM-MEMORY | MICE DEFICIENT | ADULT HIPPOCAMPUS | LENTIVIRUS VECTOR | INDUCED IMPAIRMENTS | ANTIDEPRESSANT TREATMENT | ELEMENT-BINDING PROTEIN | RAT-BRAIN | RADIAL-ARM MAZE | NEUROSCIENCES | PDE4 INHIBITORS | Memory - drug effects | Male | Green Fluorescent Proteins - genetics | Hippocampus - drug effects | MicroRNAs - pharmacology | Recognition (Psychology) - physiology | SOXB1 Transcription Factors - metabolism | Neurogenesis - genetics | CREB-Binding Protein - metabolism | Exploratory Behavior - physiology | Cyclic Nucleotide Phosphodiesterases, Type 4 - deficiency | Time Factors | Exploratory Behavior - drug effects | Neurogenesis - drug effects | Bromodeoxyuridine - metabolism | RNA Interference - physiology | Rolipram - pharmacology | Cyclic AMP - metabolism | Maze Learning - physiology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Signal Transduction - genetics | Avoidance Learning - physiology | Hippocampus - cytology | Maze Learning - drug effects | Phosphodiesterase 4 Inhibitors - pharmacology | Mice, Inbred ICR | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Neuropsychological Tests | Hippocampus - metabolism | Animals | Recognition (Psychology) - drug effects | Analysis of Variance | Signal Transduction - drug effects | Neurogenesis - physiology | Signal Transduction - physiology | Avoidance Learning - drug effects | Mice | Memory - physiology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2015, Volume 35, Issue 37, pp. 12733 - 12752
Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid that is essential in brain development and has structural and signaling roles. Acute DHA... 
Neuroplasticity | Docosahexaenoic acid | Spinal cord injury | Omega-3 polyunsaturated fatty acids | spinal cord injury | NERVOUS-SYSTEM | PTEN INHIBITION | SYNAPTIC PLASTICITY | NEUROSCIENCES | omega-3 polyunsaturated fatty acids | IN-VITRO | TRAUMATIC BRAIN-INJURY | ADULT-RAT | docosahexaenoic acid | CORTICOSPINAL TRACT | POLYUNSATURATED FATTY-ACIDS | PTEN/MTOR PATHWAY | EXPRESSION | neuroplasticity | Pyramidal Tracts - drug effects | Nerve Regeneration - physiology | Neuronal Plasticity - drug effects | Serotonergic Neurons - ultrastructure | Neuronal Plasticity - physiology | Neuroprotective Agents - pharmacology | Neurites - ultrastructure | Pyramidal Tracts - injuries | Exploratory Behavior - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Pyramidal Tracts - pathology | Neurites - drug effects | Docosahexaenoic Acids - therapeutic use | PTEN Phosphohydrolase - genetics | Cervical Vertebrae | Motor Neurons - physiology | Serotonergic Neurons - physiology | PTEN Phosphohydrolase - biosynthesis | Rats | MicroRNAs - biosynthesis | Rats, Sprague-Dawley | Spinal Cord - physiology | Nerve Regeneration - drug effects | Mice | MicroRNAs - genetics | Gait Disorders, Neurologic - etiology | Neuroprotective Agents - therapeutic use | Interneurons - physiology | Injections, Intravenous | Spinal Cord - drug effects | Spinal Cord Injuries - drug therapy | Spinal Cord Injuries - complications | Protein Processing, Post-Translational - drug effects | Female | Drug Evaluation, Preclinical | Neuroprotective Agents - administration & dosage | Pyramidal Tracts - physiology | Motor Neurons - drug effects | Cells, Cultured | Interneurons - drug effects | Docosahexaenoic Acids - administration & dosage | Nerve Tissue Proteins - genetics | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Docosahexaenoic Acids - pharmacology | Animals | Gait Disorders, Neurologic - drug therapy | Spinal Cord Injuries - physiopathology
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1393 - 1393
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 402, pp. 1 - 8
Abstract Treatment of pancreatic cancer with gemcitabine (GEM) is limited due to its rapid plasma metabolism and development of chemoresistance. MicroRNA... 
Hematology, Oncology and Palliative Medicine | Drug delivery | MicroRNA | Gemcitabine | Tumor suppressor | Pancreatic cancer | Chemoresistance | INITIATING CELLS | MIR-200 FAMILY | EPITHELIAL-MESENCHYMAL TRANSITION | REVERSES GEMCITABINE RESISTANCE | ONCOLOGY | RIBONUCLEOTIDE REDUCTASE M1 | MULTIDRUG-RESISTANCE | EXPRESSION | CARCINOMA | CAVEOLIN-1 | Deoxycytidine - chemistry | Injections, Intravenous | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Deoxycytidine - pharmacology | Epithelial-Mesenchymal Transition - drug effects | Ki-67 Antigen - metabolism | Male | MicroRNAs - metabolism | Antimetabolites, Antineoplastic - administration & dosage | Drug Carriers | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Transfection | Neoplastic Stem Cells - metabolism | Time Factors | Micelles | Drug Compounding | Neoplastic Stem Cells - pathology | Antimetabolites, Antineoplastic - pharmacology | Neoplasm Invasiveness | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Antimetabolites, Antineoplastic - chemistry | Caveolin 1 - metabolism | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Drug Resistance, Neoplasm - genetics | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Cell Line, Tumor | Polymers - chemistry | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Deoxycytidine - analogs & derivatives | Drugs | Ethylene glycol | Drug delivery systems | Drug resistance | Vehicles | Prevention | Analysis | Stem cells | Physiological aspects | Carbonates | Cancer | Cell proliferation | Caveolin-1 | Animal models | Intravenous administration | Ethylene | Metastasis | Chemosensitization | Tissues | Grafting | Polyethylene glycol | Rodents | Video compression | Inhibition | Caveolin | Markers | MiRNA | Metabolism | MPEG encoders | Spheroids | Propylene | Ribonucleic acids | MicroRNAs | Medical prognosis | Dodecanol | Tumor suppressor genes | Tumors | Apoptosis
Journal Article