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Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 267 - 271
Journal Article
Neuron, ISSN 0896-6273, 12/2016, Volume 92, Issue 5, pp. 949 - 958
Zika virus (ZIVK) represents a new threat to global health, with particular relevance to neuroscientists, due to associated newborn and adult neurological... 
microcephaly | acute flaccid paralysis | vertical transmission | neurovirology | antibody-mediated enhancement | interferon | Guillain-Barré syndrome | Zika | flavivirus | NEURAL PROGENITORS | FLACCID PARALYSIS | STEM-CELLS | WEST-NILE-VIRUS | CONGENITAL CYTOMEGALOVIRUS-INFECTION | CROSS-REACTIVITY | CENTRAL-NERVOUS-SYSTEM | VERTICAL TRANSMISSION | DENGUE VIRUS | NEUROSCIENCES | BRAIN | Meningoencephalitis - physiopathology | Pregnancy Complications, Infectious - virology | Blindness - physiopathology | Humans | Brain - virology | Interferons - immunology | Microcephaly - virology | Pregnancy Complications, Infectious - physiopathology | Meningoencephalitis - immunology | Pregnancy Complications, Infectious - immunology | Zika Virus Infection - virology | Microcephaly - immunology | Female | Microcephaly - physiopathology | Infant, Newborn | Zika Virus - pathogenicity | Cognitive Dysfunction - virology | Cell Survival | Zika Virus Infection - physiopathology | Brain - physiopathology | Neural Stem Cells - virology | Zika Virus - physiology | Retinal Neurons - virology | Guillain-Barre Syndrome - physiopathology | Cognitive Dysfunction - physiopathology | Pregnancy | Guillain-Barre Syndrome - immunology | Meningoencephalitis - virology | Neurogenesis - physiology | Zika Virus Infection - immunology | Guillain-Barre Syndrome - virology | Blindness - virology | Brain - immunology | Nervous system diseases | Guillain-Barre syndrome | Neurons | Cell death | Analysis | Stem cells | Disease susceptibility | Health aspects | Neurophysiology | Interferon | Paralysis | Biological response modifiers | Brain | Encephalitis | Neurosciences | Congenital diseases | Pandemics | Disease | Neurobiology | Zika virus | Infections | Vaccines | Kinases | Microcephaly | Proteins | Mosquitoes | Rodents | Meningitis
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 05/2017, Volume 64, Issue 10, pp. 1302 - 1308
Congenital Zika virus infection has stimulated great international concern. A prospective case series of 87 infants with laboratory- confirmed congenital Zika... 
microcephaly | diaphragm paralysis | congenital Zika syndrome (CZS) | Zika virus; immunoglobulin M | INFECTIOUS DISEASES | DIAPHRAGMATIC PARALYSIS | VIRUS-INFECTION | immunoglobulin M | ANTIBODY | MICROBIOLOGY | Zika virus | IMMUNOLOGY | INFANTS | ASSOCIATION | Neuroimaging | Pregnancy Complications, Infectious - virology | Prospective Studies | Zika Virus Infection - congenital | Humans | Arthrogryposis - epidemiology | Brain - virology | Infant | Brain - abnormalities | Nervous System Malformations - diagnostic imaging | Cerebellum - abnormalities | Antibodies, Viral - blood | Microcephaly - epidemiology | Microcephaly - virology | Mothers | Developmental Disabilities - diagnostic imaging | Arthrogryposis - virology | Zika Virus Infection - virology | Cerebellum - diagnostic imaging | Fetal Diseases - epidemiology | Ultrasonography | Female | Antibodies, Viral - cerebrospinal fluid | Brazil - epidemiology | Zika Virus - immunology | Respiratory Paralysis - diagnostic imaging | Pregnancy Complications, Infectious - epidemiology | Respiratory Paralysis - virology | Microcephaly - diagnostic imaging | Zika Virus - isolation & purification | Gestational Age | Epidemics - statistics & numerical data | Nervous System Malformations - epidemiology | Cerebellum - virology | Fetal Diseases - virology | Developmental Disabilities - epidemiology | Nervous System Malformations - virology | Pregnancy | Respiratory Paralysis - epidemiology | Immunoglobulin M - blood | Zika Virus Infection - epidemiology | Immunoglobulin M - cerebrospinal fluid | Developmental Disabilities - virology
Journal Article
JAMA, ISSN 0098-7484, 01/2017, Volume 317, Issue 1, pp. 59 - 68
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10047, pp. 898 - 904
Summary Background Zika virus is an arthropod-borne virus that is a member of the family Flaviviridae transmitted mainly by mosquitoes of the genus Aedes .... 
Internal Medicine | ETIOLOGY | MEDICINE, GENERAL & INTERNAL | STATES | VIRUS-INFECTION | ARTHROGRYPOSIS | UPDATE | TISSUES | BRAIN | PCR | Pregnancy Trimester, Second | Limb Deformities, Congenital - virology | Pregnancy Complications, Infectious - virology | Neuroglia - pathology | Zika Virus Infection - congenital | Humans | Abortion, Spontaneous - virology | Brain - virology | Infant | Male | Microcephaly - virology | Pregnancy Trimester, First | Pregnancy Trimester, Third | Antigens, Viral - isolation & purification | Autopsy | Microcephaly - pathology | Fatal Outcome | Brazil | Adult | Female | RNA, Viral - isolation & purification | Zika Virus - immunology | Zika Virus Infection - pathology | Zika Virus - isolation & purification | Reverse Transcriptase Polymerase Chain Reaction | Pregnancy Complications, Infectious - pathology | Syndrome | Immunohistochemistry - methods | Pregnancy | Ultrasonography, Prenatal | Limb Deformities, Congenital - diagnostic imaging | Placenta - pathology | Brain - pathology | Neuroglia - virology | Placenta - virology | Virus diseases | Mosquitoes | Lung diseases | Birth defects | Conjunctivitis | Health aspects | Hyperthermia | Abortion | Fever | Zoonoses | Diseases | Disease transmission | Genetic disorders | Analysis | Pathology | Zika virus | Congenital diseases | Maternal & child health | Newborn babies | Health risk assessment
Journal Article
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 11/2017, Volume 11, Issue 11, p. e0005933
Journal Article