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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 33, pp. 14657 - 14661
Neural stem cells have a broad differentiation repertoire during embryonic development and can be reprogrammed to pluripotency comparatively easily. We report... 
Phagocytes | Monocytes | Neurons | Somatic cells | Stem cells | Cell lines | Neural stem cells | Pluripotent stem cells | Embryonic stem cells | Cells | Ets transcription factor | PU.1 | Transdifferentiation | Microglia | NERVOUS-SYSTEM | CONVERSION | MULTIDISCIPLINARY SCIENCES | PLURIPOTENCY | IDENTIFICATION | LENTIVIRAL VECTORS | FIBROBLASTS | CHEMOATTRACTANT | IN-VIVO | transdifferentiation | DIFFERENTIATION | microglia | PLASTICITY | Immunohistochemistry | Monocytes - cytology | Humans | Male | Monocytes - metabolism | Neurons - cytology | Green Fluorescent Proteins - genetics | Stem Cells - cytology | Stem Cells - metabolism | Embryo, Mammalian - metabolism | Cellular Reprogramming | Time Factors | Trans-Activators - genetics | Female | Lentivirus - genetics | Neurons - metabolism | Calcium-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Green Fluorescent Proteins - metabolism | Transduction, Genetic | Mice, Inbred C57BL | Cells, Cultured | Proto-Oncogene Proteins - genetics | Pregnancy | Microscopy, Confocal | Animals | Embryo, Mammalian - cytology | Microfilament Proteins | Trans-Activators - metabolism | Mice | Transcription factors | Growth | Physiological aspects | Genetic aspects | Gene expression | Cell differentiation | Properties | Embryology | Embryos | Genes | Index Medicus | Biological Sciences
Journal Article
Frontiers in Immunology, 03/2015, Volume 6
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS). Accumulation of brain damage in progressive MS is... 
Multiple Sclerosis | Immune metabolism | EAE | Macrophages | Microglia | Warburg effect
Journal Article
Neuron, ISSN 0896-6273, 02/2019, Volume 101, Issue 3, pp. 472 - 485.e7
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. 4476 - 4481
Inhibition of the vascular endothelial growth factor (VEGF) pathway has failed to improve overall survival of patients with glioblastoma (GBM). We previously... 
Anti-angiogenic therapy | Macrophage polarization | Tumor microenvironment | Microglia reprogramming | Anti-tumor immunity | anti-angiogenic therapy | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | macrophage polarization | RANDOMIZED-TRIAL | ANGIOPOIETIN-2 | CANCER | THERAPY | microglia reprogramming | TIE2-EXPRESSING MONOCYTES | BLOOD-VESSELS | TUMOR-ASSOCIATED MACROPHAGES | tumor microenvironment | NORMALIZATION | anti-tumor immunity | ENDOTHELIAL GROWTH-FACTOR | Macrophages - pathology | Antibodies, Bispecific - pharmacology | Vesicular Transport Proteins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neoplasms, Experimental - pathology | Xenograft Model Antitumor Assays | Macrophages - metabolism | Vesicular Transport Proteins - antagonists & inhibitors | Animals | Antibodies, Neoplasm - pharmacology | Ribonuclease, Pancreatic - metabolism | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Mice | Neoplasms, Experimental - metabolism | Glioblastoma - drug therapy | Ribonuclease, Pancreatic - antagonists & inhibitors | Neoplasms, Experimental - drug therapy | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Models | Macrophages | Vascular endothelial growth factor | Health aspects | Glioblastoma multiforme | Genotype & phenotype | Survival analysis | Protein expression | Cells | Tumors | Cancer | Index Medicus | Biological Sciences
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 07/2018, Volume 347, pp. 26 - 36
Finding a neuroprotective strategy to rescue patients suffering from acute brain damage is of great interest. Monophosphoryl lipid A (MPL) is a derivative of... 
Stroke | TLRs reprogramming | Hippocampal ischemia | Preconditioning | CELLS | TOLERANCE | INJURY | NEUROSCIENCES | LESIONS | PROTECTS | MEMORY | MICROGLIA | BEHAVIORAL SCIENCES | TLR4 | BRAIN | Ischemia | Brain damage | Bone morphogenetic proteins | Lipids | Interferon | Transforming growth factors | Biological response modifiers | Mitogens
Journal Article