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1. Full Text In vivo erythrocyte micronucleus assay. III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test
by Hayashi, Makoto and MacGregor, James T and Gatehouse, David G and Blakey, David H and Dertinger, Stephen D and Abramsson-Zetterberg, Lilianne and Krishna, Gopala and Morita, Takeshi and Russo, Antonella and Asano, Norihide and Suzuki, Hiroshi and Ohyama, Wakako and Gibson, Dave and In Vivo Micronucleus Assay Working Group, IWGT
Mutation research. Genetic toxicology and environmental mutagenesis, ISSN 1383-5718, 02/2007, Volume 627, Issue 1, pp. 10 - 30
Liver micronucleus assay | Validation | Flow cytometry | Automation | Micronucleus assay | Rat blood micronucleus assay | Germ cell micronucleus assay | Skin micronucleus assay | Colon micronucleus assay | Toxicology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Cell differentiation, maturation, development, hematopoiesis | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Dose-Response Relationship, Drug | Reproducibility of Results | Animals | Reticulocytes - drug effects | Image Processing, Computer-Assisted | Reticulocytes - cytology | Micronucleus Tests - methods | Cells, Cultured | Rats | Bone Marrow | Erythrocytes - drug effects | Hematopoietic System - cytology | Index Medicus
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2. Full Text Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
by Bartsch, Kareen and Knittler, Katharina and Borowski, Christopher and Rudnik, Sönke and Damme, Markus and Aden, Konrad and Spehlmann, Martina E and Frey, Norbert and Saftig, Paul and Chalaris, Athena and Rabe, Björn
Human molecular genetics, ISSN 0964-6906, 10/2017, Volume 26, Issue 20, pp. 3960 - 3972
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Autoimmune Diseases of the Nervous System - enzymology | Nervous System Malformations - pathology | Ribonuclease H - deficiency | DNA Replication | Micronucleus, Germline - genetics | Autoimmune Diseases of the Nervous System - pathology | Micronucleus, Germline - immunology | Mice, Knockout | DNA - genetics | Animals | Nervous System Malformations - enzymology | Nervous System Malformations - metabolism | Autoimmune Diseases of the Nervous System - genetics | Mice | Autophagy - genetics | DNA Damage | Mutation | Autoimmune Diseases of the Nervous System - metabolism | Nervous System Malformations - genetics | Micronucleus, Germline - enzymology | Ribonuclease H - genetics | Ribonuclease H - metabolism | Index Medicus
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3. Full Text The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay – An update and expanded photogallery
by Bolognesi, Claudia and Knasmueller, Siegfried and Nersesyan, Armen and Thomas, Philip and Fenech, Michael
Mutation research. Reviews in mutation research, ISSN 1383-5742, 10/2013, Volume 753, Issue 2, pp. 100 - 113
Biomonitoring | Buccal micronucleus cytome assay (BMcyt) | Exfoliated cells | DNA damage | Toxicology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Molecular genetics | Mutagenesis. Repair | Mouth Mucosa - cytology | Animals | Micronucleus Tests - standards | Micronucleus Tests - methods | Humans | Cell Death | Cell Differentiation | Mouth Mucosa - pathology
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4. Full Text Correlation of in vivo versus in vitro Benchmark doses (BMDs) derived from micronucleus test data: A proof of concept study
by Soeteman-Hernández, Lya G and Fellows, Mick D and Johnson, George E and Slob, Wout
Toxicological sciences, ISSN 1096-6080, 12/2015, Volume 148, Issue 2, pp. 355 - 367
Genotoxic potenc | In vitro micronucleus | TK6 cells, benchmark dose approach | Life Sciences & Biomedicine | Toxicology | Science & Technology | Cell Line | Reproducibility of Results | Micronucleus Tests - standards | Risk Assessment | Humans | Animal Testing Alternatives - standards | Benchmarking - standards | Dose-Response Relationship, Drug | Lymphocytes - pathology | Animals | Micronuclei, Chromosome-Defective - chemically induced | Models, Biological | Lymphocytes - drug effects | Index Medicus | in vitro micronucleus | genotoxic potency | Benchmark Doses and Micronucleus Test Data
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5. Full Text Contribution of ionic silver to genotoxic potential of nanosilver in human liver HepG2 and colon Caco2 cells evaluated by the cytokinesis‐block micronucleus assay
by Sahu, Saura C and Roy, Shambhu and Zheng, Jiwen and Ihrie, John
Journal of applied toxicology, ISSN 0260-437X, 04/2016, Volume 36, Issue 4, pp. 532 - 542
genotoxicity | micronucleus | nanoparticles | silver nanoparticles | Caco2 | nanosilver | HepG2 | cytokinesis‐block micronucleus | in vitro micronucleus | Nanoparticles | Genotoxicity | Micronucleus | Nanosilver | Cytokinesis-block micronucleus | Silver nanoparticles | Life Sciences & Biomedicine | Toxicology | Science & Technology | Caco-2 Cells | Colon - cytology | DNA Damage - drug effects | Mutagens - toxicity | Micronucleus Tests - methods | Humans | Liver - metabolism | Metal Nanoparticles - chemistry | Colon - drug effects | Silver - chemistry | Linear Models | Colon - metabolism | Hep G2 Cells | Metal Nanoparticles - toxicity | Liver - drug effects | Endpoint Determination | Silver - toxicity | Liver - cytology | Cytokinesis - drug effects | Liver | Silver | Cytokines | Toxicity | Index Medicus | Human | Concentration (composition) | In vitro testing | Nanostructure | Assaying | Acetates
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6. Full Text The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps
by Holland, Nina and Bolognesi, Claudia and Kirsch-Volders, Micheline and Bonassi, Stefano and Zeiger, Errol and Knasmueller, Siegfried and Fenech, Michael
Mutation research. Reviews in mutation research, ISSN 1383-5742, 2008, Volume 659, Issue 1, pp. 93 - 108
Environmental exposure | Biomonitoring | Exfoliated cell | Genotoxicity | Biomarkers | Vitamin deficiency | Occupational exposure | Precancerous lesion | Scoring criteria | Cancer | Oral epithelia | Smoking | Fundamental and applied biological sciences. Psychology | Toxicology | Molecular genetics | Biological and medical sciences | Metabolic diseases | Other nutritional diseases (malnutrition, nutritional and vitamin deficiencies...) | Molecular and cellular biology | Medical sciences | Mutagenesis. Repair | Tobacco, tobacco smoking | Mouth Mucosa - cytology | Validation Studies as Topic | Micronucleus Tests - standards | Micronucleus Tests - methods | Humans | DNA Damage | Environmental Pollutants - toxicity | Forecasting | Evaluation Studies as Topic | Micronucleus Tests - trends | Genetic research | Occupational health and safety | DNA damage | DNA | Biological monitoring | Public health | Index Medicus
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7. Full Text Lack of genotoxic effect of food dyes amaranth, sunset yellow and tartrazine and their metabolites in the gut micronucleus assay in mice
by Poul, Martine and Jarry, Gérard and Elhkim, Mostafa Ould and Poul, Jean-Michel
Food and chemical toxicology, ISSN 0278-6915, 2009, Volume 47, Issue 2, pp. 443 - 448
Mouse | Metabolism | Food dyes | Gut micronucleus test | Genotoxicity | Food Science & Technology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Azo Compounds - pharmacokinetics | Mutagens - toxicity | Mutagens - pharmacokinetics | Colon - drug effects | Intestinal Mucosa - drug effects | Dose-Response Relationship, Drug | Micronucleus Tests | Tartrazine - toxicity | Amaranth Dye - pharmacokinetics | Mutagens - classification | Amaranth Dye - analysis | Coloring Agents - toxicity | Tartrazine - analysis | Administration, Oral | Colon - pathology | Azo Compounds - analysis | Azo Compounds - toxicity | Comet Assay | Coloring Agents - analysis | Animals | Feces - chemistry | Mitosis - drug effects | Micronuclei, Chromosome-Defective - chemically induced | Coloring Agents - pharmacokinetics | Mice | Amaranth Dye - toxicity | DNA Damage | Tartrazine - pharmacokinetics | Intestinal Mucosa - pathology | Food colorings | Metabolites | Amino compounds | Dyes and dyeing | Index Medicus | Intestinal Mucosa | Micronuclei, Chromosome-Defective | Mitosis | Coloring Agents | Amaranth Dye | Life Sciences | Mutagens | Azo Compounds | Colon | Feces | Tartrazine
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8. Full Text A review of the genotoxicity of the industrial chemical cumene
by Gollapudi, B. Bhaskar and Williams, Amy L and Bus, James S
Mutation research. Reviews in mutation research, ISSN 1383-5742, 01/2021, Volume 787
Clastogenicity | DNA damage | Genotoxicity | Micronucleus | Aneugenicity | Mutation
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9. Full Text Role of the crystalline form of titanium dioxide nanoparticles: Rutile, and not anatase, induces toxic effects in Balb/3T3 mouse fibroblasts
by Uboldi, Chiara and Urbán, Patricia and Gilliland, Douglas and Bajak, Edyta and Valsami-Jones, Eugenia and Ponti, Jessica and Rossi, François
Toxicology in vitro, ISSN 0887-2333, 03/2016, Volume 31, pp. 137 - 145
Cytotoxicity | Titanium dioxide nanoparticles | Uptake | Genotoxicity | Micronucleus | Morphological neoplastic transformation | Life Sciences & Biomedicine | Toxicology | Science & Technology | Cell Survival - drug effects | Microscopy, Electron, Transmission | Mutagens - chemistry | Mutagens - toxicity | Titanium - pharmacology | Metal Nanoparticles - chemistry | Titanium - chemistry | BALB 3T3 Cells | Micronucleus Tests | Titanium - toxicity | Metal Nanoparticles - toxicity | Animals | Biological Transport | Mice | Cell Transformation, Neoplastic - drug effects | Metal Nanoparticles - ultrastructure | Nanoparticles | Titanium dioxide | Index Medicus | Life Sciences
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