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1. Full Text Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?
by Handy, R.D and Brink, van den, N.W and Chappell, M and Muhling, M and Behra, R and Dusinska, M and Simpson, P and Ahtiainen, J and Jha, A.N and Seiter, J and Bednar, A and Kennedy, A and Fernandes, T.F and Riediker, M
Ecotoxicology, ISSN 0963-9292, 2012, Volume 21, Issue 4, pp. 933 - 972
This review paper reports the consensus of a technical workshop hosted by the European network, NanoImpactNet (NIN). The workshop aimed to review the... 
Environment, general | Earthworm | Gram positive Bacteria | Ecotoxicology | OECD test method | Environment | Ecology | Bioaccumulation factor tests | Nanoparticle characterisation | Environmental Management | Aquatic tests | FULLERENE WATER SUSPENSIONS | RAINBOW-TROUT | ENVIRONMENTAL RISK-ASSESSMENT | ONCORHYNCHUS-MYKISS | NEMATODE CAENORHABDITIS-ELEGANS | SILVER NANOPARTICLES | MICRONUCLEUS ASSAY | ENGINEERED NANOMATERIALS | ENVIRONMENTAL SCIENCES | ECOLOGY | TOXICOLOGY | TITANIUM-DIOXIDE NANOPARTICLES | WALLED CARBON-NANOTUBES | Fishes - metabolism | Guidelines as Topic | Ecotoxicology - methods | Comet Assay - methods | Micronucleus Tests - methods | Soil Microbiology | Metals - toxicity | Particle Size | Animals | Microscopy, Electron - methods | Endpoint Determination | Nanostructures - chemistry | Biological Assay | Toxicity Tests - methods | Nanostructures - toxicity | Animal culture | Ecosystem components | Analysis | Phytochemistry | Bacteria | Wastewater | Photosynthesis | Methods | Chromatography | Nanotechnology | Logistics | Index Medicus | Microorganisms | Dispersing | Toxicity | Media | Nanomaterials | Nanostructure | Dispersions | Assaying | nematode caenorhabditis-elegans | soil microbial community | silver nanoparticles | dna strand breaks | in-vitro | environmental risk-assessment | rainbow-trout | titanium-dioxide nanoparticles | walled carbon-nanotubes | fullerene water suspensions
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2. Full Text Cytokinesis-block micronucleus cytome assay
by Fenech, Michael
Nature Protocols, ISSN 1754-2189, 05/2007, Volume 2, Issue 5, pp. 1084 - 1104
The cytokinesis-block micronucleus cytome assay is a comprehensive system for measuring DNA damage, cytostasis and cytotoxicity. DNA damage events are scored... 
REDUCTASE C677T POLYMORPHISM | CHINESE-HAMSTER CELLS | RADIATION-INDUCED MICRONUCLEI | BIOCHEMICAL RESEARCH METHODS | IN-SITU HYBRIDIZATION | BINUCLEATED HUMAN-LYMPHOCYTES | FOLIC-ACID DEFICIENCY | CHEMICALLY-INDUCED ANEUPLOIDY | CYTOCHALASIN-B | NUCLEOPLASMIC BRIDGES | CHROMOSOMAL INSTABILITY | Mutagens - toxicity | Apoptosis - drug effects | Micronucleus Tests - methods | Biomarkers - analysis | Environmental Monitoring - methods | DNA Damage | Cytokinesis - drug effects
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3. Full Text Can Standard Genotoxicity Tests be Applied to Nanoparticles?
by Magdolenova, Zuzana and Lorenzo, Yolanda and Collins, Andrew and Dusinska, Maria
Journal of Toxicology and Environmental Health, Part A, ISSN 1528-7394, 07/2012, Volume 75, Issue 13-15, pp. 800 - 806
Experiments were conducted to determine the validity of two common genotoxicity testing procedures, the comet assay and the micronucleus (MN) test, when... 
Cytochalasin B - pharmacology | DNA Breaks - drug effects | Nanoparticles - chemistry | Comet Assay - methods | Micronucleus Tests - methods | Endocytosis - drug effects | Humans | Metal Nanoparticles - chemistry | Cercopithecus aethiops | DNA - metabolism | DNA-Formamidopyrimidine Glycosylase - metabolism | Endonucleases - metabolism | Neoplasm Proteins - metabolism | Nanoparticles - toxicity | Materials Testing - methods | Particle Size | Metal Nanoparticles - toxicity | Animals | Toxicity Tests - methods | HeLa Cells | COS Cells | Chromosome Aberrations - chemically induced | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY
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4. Full Text Using the comet and micronucleus assays for genotoxicity studies: A review
by Araldi, Rodrigo Pinheiro and de Melo, Thatiana Corrêa and Mendes, Thais Biude and de Sá Júnior, Paulo Luiz and Nozima, Bruno Heidi Nakano and Ito, Eliana Tiemi and de Carvalho, Rodrigo Franco and de Souza, Edislane Barreiros and de Cassia Stocco, Rita
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2015, Volume 72, pp. 74 - 82
Abstract Physical, chemical and biological agents can act in the DNA, resulting in mutation involved in cancer. Thus, genotoxic tests are required by... 
Internal Medicine | Medical Education | Genotoxicity tests | Mutagenesis | Micronucleus assay | Comet assay | MEDICINE, RESEARCH & EXPERIMENTAL | DNA-DAMAGE RESPONSE | STAINING METHOD | MONONUCLEAR-CELLS | PAPILLOMAVIRUS TYPE-16 E6 | GENOMIC INSTABILITY | IN-VIVO | PERIPHERAL-BLOOD RETICULOCYTES | GEL-ELECTROPHORESIS ASSAY | PHARMACOLOGY & PHARMACY | ALKALINE COMET | FLOW-CYTOMETRY | Animals | Comet Assay - methods | Micronucleus Tests - methods | Models, Biological | Humans | Mutagenesis - genetics | Mutagenicity Tests - methods
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5. Full Text In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells
by Kawata, Koji and Osawa, Masato and Okabe, Satoshi
Environmental Science and Technology, ISSN 0013-936X, 08/2009, Volume 43, Issue 15, pp. 6046 - 6051
Although it has been reported that silver nanoparticles (Ag-NPs) have strong acute toxic effects to various cultured the toxic effects at noncytotoxic doses... 
RECOMBINATION | ENVIRONMENTAL SCIENCES | OXIDATIVE STRESS | RAD51 | ENGINEERING, ENVIRONMENTAL | TISSUE DISTRIBUTION | PROTEIN-KINASE | DNA-DAMAGE | MAMMALIAN-CELLS | CANCER | CYTOTOXICITY | CYCLE | Drug Screening Assays, Antitumor - methods | Reactive Oxygen Species | Oligonucleotide Array Sequence Analysis | Oxidative Stress | Micronucleus Tests - methods | Nanotechnology - methods | Humans | Metal Nanoparticles - chemistry | Silver - chemistry | Ions | Gene Expression Profiling | Cysteine - chemistry | Metal Nanoparticles - toxicity | Cell Line, Tumor | Silver - toxicity | DNA Damage | Gene Expression Regulation, Neoplastic - drug effects
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6. Full Text Genotoxicity effects of Phanerochaete chrysosporium against harmful algal bloom species by micronucleus test and comet assay
by Zeng, Guoming and Zhang, Maolan and Wang, Pu and Li, Xiang and Wu, Pei and Sun, Da
Chemosphere, ISSN 0045-6535, 03/2019, Volume 218, pp. 1031 - 1041
Algal blooms and toxins have become serious ecological problems. White-rot fungi have been demonstrated to be a feasible means of control, but the genotoxicity... 
Algal bloom | Fejervarya multistriat tadpoles | Phanerochaete chrysosporium | Genotoxicity | MECHANISM | DNA-DAMAGE | TADPOLES | TOXICITY | ENVIRONMENTAL SCIENCES | DUST | IN-VIVO | FREQUENCY | DRINKING-WATER | MARINE | EXPOSURE | Biodegradation, Environmental - drug effects | Harmful Algal Bloom - drug effects | Comet Assay - methods | Micronucleus Tests - methods | Phanerochaete - drug effects | Index Medicus
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7. Full Text The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance
by Kirsch-Volders, Micheline and Plas, Gina and Elhajouji, Azeddine and Lukamowicz, Magdalena and Gonzalez, Laetitia and Vande Loock, Kim and Decordier, Ilse
Archives of Toxicology, ISSN 0340-5761, 8/2011, Volume 85, Issue 8, pp. 873 - 899
Micronuclei (MN) are small, extranuclear bodies that arise in dividing cells from acentric chromosome/chromatid fragments or whole chromosomes/chromatids... 
Cytokinesis-block micronucleus assay | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Micronuclei | Genotoxicity | Pharmacology/Toxicology | Biomedicine general | HUMAN BUCCAL CELLS | AUTOMATED IMAGE-ANALYSIS | CYTOKINESIS-BLOCKED LYMPHOCYTES | RADIATION-INDUCED MICRONUCLEI | CULTURED HUMAN-LYMPHOCYTES | BREAST-CANCER PATIENTS | TOXICOLOGY | FLOW-CYTOMETRIC ANALYSIS | PERIPHERAL-BLOOD LYMPHOCYTES | MAMMALIAN-CELL CULTURES | DISCRIMINATE RODENT CARCINOGENS | Risk Assessment - methods | Mutagens - toxicity | Animals | Micronucleus Tests - methods | Humans | Micronuclei, Chromosome-Defective - drug effects | Carcinogens - toxicity | High-Throughput Screening Assays - methods | Digital integrated circuits | Analysis | Methods | Toxicology | Carcinogens | Cellular biology | Biological assays | Index Medicus
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8. Full Text A retrospective evaluation method for in vitro mammalian genotoxicity tests using cytotoxicity index transformation formulae
by Fujita, Yurika and Kasamatsu, Toshio and Ikeda, Naohiro and Nishiyama, Naohiro and Honda, Hiroshi
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, ISSN 1383-5718, 01/2016, Volume 796, pp. 1 - 7
Although chromosomal aberration tests and micronucleus tests have been widely used for genotoxicity evaluation, false–positive results have been reported under... 
Cytotoxicity | Micronucleus test | False positive | Chromosomal aberration test | Genotoxicity | WORKSHOP | ASSAY | SENSITIVITY | CARCINOGENS | PREDICTIVITY | REDUCTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | TOXICOLOGY | ABERRATION TEST | Cell Survival - drug effects | Guidelines as Topic | Eugenol - toxicity | Micronucleus Tests - methods | Cell Count | Humans | Cells, Cultured | Mammals | Mutagenicity Tests - methods | Acrylates - toxicity | Nitrophenols - toxicity | Animals | Retrospective Studies | DNA Damage | Chromosome Aberrations - chemically induced | Mutagenicity Tests - standards | Index Medicus
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9. Full Text Comet assay and micronucleus tests on Oreochromis niloticus (Perciforme: Cichlidae) exposed to raw sugarcane vinasse and to phisicochemical treated vinasse by pH adjustment with lime (CaO)
by Correia, Jorge E and Christofoletti, Cintya Ap and Ansoar-Rodríguez, Yadira and Guedes, Thays A and Fontanetti, Carmem S
Chemosphere, ISSN 0045-6535, 04/2017, Volume 173, pp. 494 - 501
In Brazil vinasse, a main sugarcane distillery residue, stands out because every liter of alcohol generates 10–15 L of vinasse as waste. An alternative for the... 
Ethanol industry | Chemical treatment | Agroindustrial waste | Water resources | Genotoxicity | INDIVIDUAL CELLS | ENVIRONMENTAL SCIENCES | ERYTHROCYTES | DISPOSAL | STILLAGE | FISH | DAMAGE | DNA Damage - drug effects | Comet Assay - methods | Micronucleus Tests - methods | Oxides - chemistry | Cichlids - genetics | Industrial Waste - analysis | Cichlids - growth & development | Saccharum - toxicity | Animals | Soil - chemistry | Brazil | Industrial Waste - adverse effects | Calcium Compounds - chemistry | Hydrogen-Ion Concentration | Lime | Aquatic resources | Hydrogen-ion concentration | Sugarcane | Fishes | Alcohol industry | Index Medicus
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10. Full Text The micronucleus test in piscine erythrocytes
by Udroiu, Ion
Aquatic Toxicology, ISSN 0166-445X, 2006, Volume 79, Issue 2, pp. 201 - 204
Cytogenetic assays on aquatic organisms are essential, as humans are exposed throughout their lifetime to several xenobiotics present in both the water and... 
Micronucleus test | Genotoxicity | FREQUENCIES | PERSISTENCE | FRESH-WATER | BIOASSAY | genotoxicity | POLLUTION | MARINE & FRESHWATER BIOLOGY | TELEOSTEI | micronucleus test | FISH | PISCES | TOXICOLOGY | PERIPHERAL-BLOOD ERYTHROCYTES | Animals | Water Pollutants, Chemical - toxicity | Micronucleus Tests - standards | Micronucleus Tests - methods | Erythropoiesis - drug effects | Fishes - blood | Erythrocytes - drug effects
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11. Full Text In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines
by Doak, S.H and Manshian, B and Jenkins, G.J.S and Singh, N
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, ISSN 1383-5718, 06/2012, Volume 745, Issue 1-2, pp. 104 - 111
► We consider current OECD genotoxicity tests for nanomaterials. ► Ames test does not appear to be suitable for nanomaterial assessment. ► HPRT and... 
Nanoparticles | Nanomaterials | Ames test | Micronucleus assay | Nanotubes | Genotoxicity | GOLD NANOPARTICLES | OXIDATIVE STRESS | ULTRAFINE TIO2 PARTICLES | ZINC-OXIDE | DNA-DAMAGE | SILVER NANOPARTICLES | CELLULAR UPTAKE | WALLED-CARBON-NANOTUBES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | ALUMINUM-OXIDE NANOMATERIALS | TOXICOLOGY | TITANIUM-DIOXIDE | Micronucleus Tests | Guidelines as Topic | Mutagens - toxicity | International Agencies | Mutagenicity Tests - methods | Nanostructures - toxicity | Forecasting | Mutagenicity Tests - standards | Nanotechnology
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12. Full Text Micronucleus test in fishes as indicators of environmental quality in subestuaries of the Río de la Plata (Uruguay)
by Gutiérrez, Juan Manuel and Villar, Silvia and Acuña Plavan, Alicia
Marine Pollution Bulletin, ISSN 0025-326X, 02/2015, Volume 91, Issue 2, pp. 518 - 523
Genotoxic agents may exert damage that may be active through following generations. Micronuclei are cytoplasmic chromatin masses outside the main cell nucleus,... 
Biomarkers | Environmental quality | Estuary | DNA damage | Micronuclei | ANIMALS | DNA-DAMAGE | INDUCTION | ESTUARY SOUTHERN BRAZIL | FRESH-WATER | POLLUTION BIOMARKERS | ENVIRONMENTAL SCIENCES | GENOTOXICITY | ERYTHROCYTES | MARINE & FRESHWATER BIOLOGY | TELEOSTEI | MARINE | Animals | Ecotoxicology - methods | Species Specificity | Micronucleus Tests - methods | Uruguay | Fishes | Estuaries | Urbanization | DNA Damage | Seasons | Water Quality | Environmental aspects
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