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Nucleic Acid Therapeutics, ISSN 2159-3337, 12/2016, Volume 26, Issue 6, pp. 363 - 371
Registration of pharmaceuticals requires an assessment of their genotoxic potential using in vitro and in vivo tests outlined in the International Conference... 
genotoxicity | hPBL | micronucleus | siRNA-GalNAc conjugate | Ames | comet | MUTAGENS | MEDICINE, RESEARCH & EXPERIMENTAL | OUTER-MEMBRANE | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | OLIGONUCLEOTIDE | CARCINOGENS | Glycoconjugates - metabolism | Cricetulus | Glycoconjugates - chemistry | Humans | Glycoconjugates - pharmacology | Bone Marrow - physiology | Acetylgalactosamine - metabolism | Micronucleus Tests | RNA, Small Interfering - chemistry | Endocytosis | Lymphocytes - physiology | DNA Breaks, Double-Stranded - drug effects | Biotransformation | Mutagenicity Tests | Bone Marrow - drug effects | CHO Cells | RNA, Small Interfering - pharmacology | Rats | RNA Cleavage | Acetylgalactosamine - chemistry | Hep G2 Cells | Animals | Lymphocytes - drug effects | HeLa Cells | Primary Cell Culture | Acetylgalactosamine - pharmacology | RNA, Small Interfering - metabolism | Cell culture | Conjugates | N-Acetylgalactosamine | Media (culture) | DNA damage | Genotoxicity | Gram-positive bacteria | Antisense | Nucleotides | Kinases | Assaying | Dosage | Proteins | Biomedical materials | Transfection | Metabolites | E coli | Lymphocytes | Ribose | Peripheral blood | Cell cycle | Bone marrow | Biocompatibility | Bacteria | Phosphorothioate | Chromosomes | Deoxyribonucleic acid--DNA | Biodegradation | Mass spectroscopy | CD3 antigen | Exposure | siRNA | Organic chemistry | Bone mass | Ames test | Reagents | Lysis | Culture media | In vivo methods and tests | Lymphomas | Mutation | Laboratory animals | Mass spectrometry | Pharmaceuticals
Journal Article
Journal Article
Toxicological & Environmental Chemistry, ISSN 0277-2248, 09/2008, Volume 90, Issue 5, pp. 1009 - 1017
The effects of pulsed current electromagnetic fields (PCEMF) on human peripheral lymphocytes sister chromatid exchanges (SCE), and micronuclei (MN) frequencies... 
pulsed current electromagnetic field | micronucleus rate | sister chromatid exchange | Pulsed current electromagnetic field | Sister chromatid exchange | Micronucleus rate
Journal Article
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