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Journal Article
Journal Article
Journal Article
Archives of toxicology, ISSN 0340-5761, 2/2017, Volume 91, Issue 2, pp. 689 - 698
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 04/2004, Volume 32, Issue 4, pp. 447 - 454
Oxycodone undergoes N -demethylation to noroxycodone and O -demethylation to oxymorphone. The cytochrome P450 (P450) isoforms capable of mediating the... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Intestines - drug effects | Microsomes - metabolism | Intestinal Mucosa - metabolism | Morphinans - antagonists & inhibitors | Oxidoreductases, N-Demethylating - genetics | Quinidine - antagonists & inhibitors | Cytochrome P-450 CYP3A | Humans | Microsomes, Liver - metabolism | Aryl Hydrocarbon Hydroxylases - genetics | DNA, Complementary - genetics | Cytochrome P-450 Enzyme System - metabolism | Ketoconazole - metabolism | Metabolic Clearance Rate | Ketoconazole - pharmacology | Microsomes - drug effects | Morphinans - metabolism | Oxymorphone - metabolism | Microsomes, Liver - drug effects | Quinidine - adverse effects | Biotransformation | Protein Binding - drug effects | Molecular Structure | Oxidoreductases, N-Demethylating - metabolism | Oxycodone - metabolism | Cytochrome P-450 CYP2D6 - genetics | Cytochrome P-450 CYP2D6 - pharmacology | Morphinans - chemistry | Aryl Hydrocarbon Hydroxylases - pharmacology | Oxycodone - pharmacology | Oxymorphone - chemistry | Quinidine - pharmacology | Microsomes, Liver - chemistry | Aryl Hydrocarbon Hydroxylases - metabolism | Intestines - ultrastructure | Oxidoreductases, N-Demethylating - pharmacology | Methylation - drug effects | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Kinetics | Index Medicus
Journal Article
Journal Article