X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (76614) 76614
Book Review (3396) 3396
Publication (2066) 2066
Book Chapter (498) 498
Conference Proceeding (159) 159
Dissertation (72) 72
Government Document (29) 29
Magazine Article (10) 10
Book / eBook (9) 9
Data Set (7) 7
Newsletter (5) 5
Newspaper Article (5) 5
Paper (4) 4
Web Resource (3) 3
Reference (2) 2
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (67857) 67857
animals (55397) 55397
rats (36010) 36010
male (30924) 30924
humans (20961) 20961
microsomes, liver - metabolism (20803) 20803
microsomes, liver - enzymology (18998) 18998
pharmacology & pharmacy (14006) 14006
female (13011) 13011
kinetics (12270) 12270
biochemistry & molecular biology (11834) 11834
cytochrome p-450 enzyme system - metabolism (11306) 11306
microsomes, liver - drug effects (11024) 11024
in vitro techniques (10755) 10755
microsomes - metabolism (10392) 10392
microsomes - enzymology (10083) 10083
microsomes (10057) 10057
mice (8937) 8937
metabolism (7889) 7889
rats, inbred strains (7083) 7083
liver - metabolism (6913) 6913
toxicology (6711) 6711
liver (6473) 6473
liver - enzymology (6017) 6017
biotransformation (5761) 5761
oxidation-reduction (5121) 5121
rabbits (4763) 4763
rats, sprague-dawley (4711) 4711
liver - drug effects (4434) 4434
enzymes (4293) 4293
human liver-microsomes (4156) 4156
time factors (4065) 4065
chromatography, high pressure liquid (3730) 3730
hydroxylation (3693) 3693
phenobarbital - pharmacology (3665) 3665
structure-activity relationship (3483) 3483
cytochrome p450 (3384) 3384
mixed function oxygenases - metabolism (3314) 3314
rats, wistar (3290) 3290
chemistry, medicinal (3218) 3218
adult (3140) 3140
dose-response relationship, drug (3138) 3138
liver-microsomes (3127) 3127
microsomes - drug effects (3125) 3125
in-vitro (3044) 3044
substrate specificity (3016) 3016
pharmacokinetics (2994) 2994
expression (2920) 2920
inhibition (2761) 2761
cytochrome p-450 (2723) 2723
species specificity (2722) 2722
drug interactions (2679) 2679
identification (2637) 2637
hydrogen-ion concentration (2623) 2623
rat (2559) 2559
biophysics (2529) 2529
protein binding (2507) 2507
enzyme induction - drug effects (2463) 2463
cattle (2457) 2457
cytochrome p-450 enzyme inhibitors (2455) 2455
enzyme inhibitors - pharmacology (2400) 2400
dogs (2332) 2332
molecular sequence data (2322) 2322
middle aged (2298) 2298
isoenzymes - metabolism (2271) 2271
metabolites (2266) 2266
cells, cultured (2257) 2257
enzyme induction (2230) 2230
nadp - metabolism (2227) 2227
amino acid sequence (2225) 2225
mass spectrometry (2204) 2204
induction (2118) 2118
proteins (2062) 2062
binding sites (2001) 2001
physiological aspects (1981) 1981
cytochrome p-450 enzyme system - biosynthesis (1965) 1965
molecular weight (1953) 1953
guinea pigs (1952) 1952
liver - cytology (1948) 1948
cell line (1942) 1942
cell biology (1932) 1932
purification (1929) 1929
oxidoreductases - metabolism (1873) 1873
cytochrome p-450 enzyme system - genetics (1870) 1870
pregnancy (1851) 1851
abridged index medicus (1842) 1842
analysis (1831) 1831
oxidation (1824) 1824
rat-liver (1794) 1794
glucuronosyltransferase - metabolism (1787) 1787
calcium - metabolism (1769) 1769
carbon isotopes (1766) 1766
tritium (1754) 1754
swine (1745) 1745
research (1717) 1717
stereoisomerism (1693) 1693
electrophoresis, polyacrylamide gel (1689) 1689
molecular structure (1632) 1632
cricetinae (1623) 1623
chemistry (1609) 1609
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (8) 8
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Gerstein Science - Theses (1) 1
UTL at Downsview - May be requested (1) 1
University Archives - Archives (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (72592) 72592
Russian (1641) 1641
German (769) 769
French (562) 562
Japanese (560) 560
Chinese (257) 257
Italian (157) 157
Polish (128) 128
Spanish (120) 120
Ukrainian (91) 91
Bulgarian (28) 28
Czech (18) 18
Korean (17) 17
Portuguese (14) 14
Hungarian (10) 10
Slovak (9) 9
Dutch (7) 7
Croatian (5) 5
Danish (4) 4
Norwegian (4) 4
Swedish (4) 4
Turkish (4) 4
Romanian (2) 2
Finnish (1) 1
Greek (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug Metabolism and Disposition, ISSN 0090-9556, 12/2017, Volume 45, Issue 12, pp. 1239 - 1239
Journal Article
1954, Protoplasmatologia : Handbuch der Protoplasmaforschung, Volume Bd. 3, T A4., 136
Book
1954, Protoplasmatologia, Volume Handbuch der Protoplasmaforschung, Bd. 3, A4, 136 p. illus.
Book
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 92 - 99
The aim of the current study is to identify the human cytochrome P450 (P450) isoforms involved in the two oxidative steps in the bioactivation of clopidogrel... 
MECHANISM-BASED INHIBITION | ANTIAGGREGATING ACTIVITY | POLYMORPHISMS | TICLOPIDINE | PHARMACOKINETICS | HEALTHY-SUBJECTS | PHARMACOLOGY & PHARMACY | PRASUGREL | PHARMACODYNAMICS | MONOCLONAL-ANTIBODIES | ATORVASTATIN | Microsomes - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Sulfaphenazole - pharmacology | Microsomes - drug effects | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Antibodies - immunology | Omeprazole - pharmacology | Microsomes, Liver - enzymology | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Oxidoreductases, N-Demethylating - metabolism | Aryl Hydrocarbon Hydroxylases - immunology | Oxidation-Reduction | Enzyme Inhibitors - pharmacology | Ticlopidine - analogs & derivatives | Oxidoreductases, N-Demethylating - immunology | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Theophylline - pharmacology | Kinetics | Cytochrome P-450 CYP2C9 | Theophylline - analogs & derivatives | Oxidoreductases, N-Demethylating - genetics | Glutathione - metabolism | Ketoconazole - pharmacology | Biotransformation - physiology | Cytochrome P-450 CYP1A2 Inhibitors | Microsomes, Liver - drug effects | Ticlopidine - metabolism | NADP - metabolism | Platelet Aggregation Inhibitors - metabolism | Cytochrome P-450 CYP3A - immunology | Cell Line | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 - immunology | Biocatalysis | Mephenytoin - analogs & derivatives | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Mephenytoin - pharmacology | Antibodies - pharmacology | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP2C19 | Clopidogrel | Cytochrome P-450 CYP2B6 | Index Medicus
Journal Article
Archives of Toxicology, ISSN 0340-5761, 9/2013, Volume 87, Issue 9, pp. 1683 - 1696
For ethical and regulatory reasons, in vitro tests for scoring potential toxicities of cosmetics are essential. A test strategy for investigating potential... 
Human dendritic cell lines | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Human keratinocytic cell lines | Biomedicine general | Xenobiotic metabolizing enzymes | RAT-LIVER | BENZYDAMINE N-OXIDATION | TEST H-CLAT | HUMAN LIVER-MICROSOMES | ESTERASE-ACTIVITY | CONTAINING MONOOXYGENASE ACTIVITY | UDP-GLUCURONOSYLTRANSFERASES | CYTOCHROME-P450 ENZYMES | CONTACT ALLERGENS | TOXICOLOGY | PARA-PHENYLENEDIAMINE | Microsomes - metabolism | Arylamine N-Acetyltransferase - metabolism | Cosmetics - toxicity | Rats, Wistar | Skin - metabolism | Humans | Microsomes, Liver - metabolism | Cytosol - drug effects | Male | Xenobiotics - toxicity | Dermatitis, Allergic Contact - metabolism | Microsomes - drug effects | Cytosol - enzymology | Cosmetics - metabolism | Isoenzymes - metabolism | Microsomes, Liver - drug effects | Dendritic Cells - drug effects | Toxicity Tests - methods | Microsomes, Liver - enzymology | Xenobiotics - metabolism | Keratinocytes - enzymology | Dendritic Cells - metabolism | Cell Line | Limit of Detection | Rats | Microsomes - enzymology | Skin - enzymology | Acetylation - drug effects | Animals | Keratinocytes - drug effects | Dendritic Cells - enzymology | Keratinocytes - metabolism | Animal Use Alternatives | Cytosol - metabolism | Dermatitis, Allergic Contact - enzymology | Skin - drug effects | Cytochrome c | Enzymes | Metabolites | Fluorescein | Hydrolases | Skin | Aldehydes | Cosmetics | Toxicology | Toxicity | Skin care products | Index Medicus
Journal Article
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2008, Volume 233, Issue 3, pp. 420 - 427
Journal Article
Journal Article
Archives of Toxicology, ISSN 0340-5761, 2/2017, Volume 91, Issue 2, pp. 689 - 698
Journal Article
Journal Article