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Cancer Research, ISSN 0008-5472, 12/2009, Volume 69, Issue 23, pp. 8844 - 8852
Transforming growth factor-beta (TGF-beta) is a multifunctional cytokine that regulates cell growth, differentiation, and apoptosis of various types of cells.... 
SURVIVAL | THERAPY | BECLIN-1 | ONCOLOGY | INDUCED APOPTOSIS | MESANGIAL CELLS | PAI-1 GENE-EXPRESSION | INDUCTION | TUMORIGENESIS | CANCER | LC3 | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Cell Growth Processes - physiology | JNK Mitogen-Activated Protein Kinases - metabolism | Autophagy - physiology | Proto-Oncogene Proteins - biosynthesis | Transforming Growth Factor beta - biosynthesis | Breast Neoplasms - metabolism | Transfection | Bcl-2-Like Protein 11 | Carcinoma, Hepatocellular - genetics | Apoptosis Regulatory Proteins - genetics | Liver Neoplasms - pathology | Apoptosis Regulatory Proteins - biosynthesis | Beclin-1 | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Membrane Proteins - genetics | Transforming Growth Factor beta - physiology | Proto-Oncogene Proteins - genetics | Microtubule-Associated Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - biosynthesis | Autophagy-Related Protein 7 | Membrane Proteins - biosynthesis | Breast Neoplasms - genetics | Transforming Growth Factor beta - genetics | Autophagy-Related Protein 5 | Membrane Proteins - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Breast Neoplasms - pathology | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - biosynthesis | Smad Proteins - metabolism | Carcinoma, Hepatocellular - metabolism | Index Medicus
Journal Article
PLoS genetics, ISSN 1553-7390, 08/2014, Volume 10, Issue 8, pp. e1004519 - e1004519
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 06/2013, Volume 1832, Issue 6, pp. 848 - 863
Sepsis is characterized by systematic inflammation and contributes to cardiac dysfunction. This study was designed to examine the effect of protein kinase B... 
Heart | ER stress | Sepsis | Akt | Contractile function | Apoptosis | OXIDATIVE STRESS | CONTRACTILE DYSFUNCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | ENDOPLASMIC-RETICULUM STRESS | AUTOPHAGY | GROWTH-FACTOR I | SIGNAL-TRANSDUCTION | SYNTHASE | BIOPHYSICS | INFLAMMATORY RESPONSE | NF-KAPPA-B | Caspase 9 - genetics | Apoptosis - drug effects | Calcium - metabolism | Heat-Shock Proteins - biosynthesis | Myocardial Contraction - drug effects | bcl-2-Associated X Protein - biosynthesis | Apoptosis - genetics | Glycogen Synthase Kinase 3 beta | Heat-Shock Proteins - genetics | Phosphorylation - genetics | Caspase 3 - genetics | Phosphorylation - drug effects | Transcription Factor CHOP - biosynthesis | Proto-Oncogene Proteins c-akt - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Lipopolysaccharides - toxicity | Endoplasmic Reticulum Stress - drug effects | Mice, Transgenic | Glycogen Synthase Kinase 3 - genetics | Eukaryotic Initiation Factor-2 - genetics | Mice | Enzyme Activation - genetics | Transcription Factor CHOP - genetics | Eukaryotic Initiation Factor-2 - biosynthesis | Microtubule-Associated Proteins - genetics | bcl-X Protein - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Endoplasmic Reticulum Stress - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Myocardial Contraction - genetics | MAP Kinase Signaling System - genetics | Apoptosis Regulatory Proteins - genetics | Caspase 3 - biosynthesis | bcl-X Protein - biosynthesis | bcl-2-Associated X Protein - genetics | Beclin-1 | Gene Expression Regulation - genetics | Myocardium - pathology | Transcription Factors - biosynthesis | Transcription Factors - genetics | Enzyme Activation - drug effects | Glycogen Synthase Kinase 3 - metabolism | Microtubule-Associated Proteins - biosynthesis | Gene Expression Regulation - drug effects | Autophagy-Related Protein 7 | Myocardium - enzymology | Animals | MAP Kinase Signaling System - drug effects | Caspase 9 - biosynthesis
Journal Article
EMBO reports, ISSN 1469-221X, 05/2014, Volume 15, Issue 5, pp. 566 - 575
Journal Article
The International Journal of Neuropsychopharmacology, ISSN 1461-1457, 6/2012, Volume 16, Issue 1, pp. 1 - 14
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2014, Volume 193, Issue 6, pp. 3080 - 3089
Coronaviruses (CoV) have recently emerged as potentially serious pathogens that can cause significant human morbidity and death. The severe acute respiratory... 
PATHOGENESIS | LOCALIZATION | ACTIVATION | ADAPTER MAVS | ANTIVIRAL SIGNALING PROTEIN | HEPATITIS-C-VIRUS | DEGRADATION | AUTOPHAGY | IMMUNOLOGY | IDENTIFICATION | ACUTE RESPIRATORY SYNDROME | SARS Virus - immunology | Green Fluorescent Proteins | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Severe Acute Respiratory Syndrome - virology | Microtubule-Associated Proteins - metabolism | Humans | Immunity, Innate - genetics | Severe Acute Respiratory Syndrome - immunology | Viral Proteins - immunology | Mitochondria - immunology | Mitochondrial Proteins - genetics | Open Reading Frames - immunology | RNA-Binding Proteins - biosynthesis | Ubiquitination | SARS Virus - genetics | Mitochondria - genetics | RNA Interference | Mitochondrial Proteins - metabolism | HEK293 Cells | Autophagy - genetics | Cell Line | Repressor Proteins - genetics | Viral Proteins - genetics | TNF Receptor-Associated Factor 3 - metabolism | Microtubule-Associated Proteins - biosynthesis | Open Reading Frames - genetics | Ubiquitin-Protein Ligases - biosynthesis | GTP Phosphohydrolases - metabolism | Immune Evasion | Repressor Proteins - biosynthesis | Autophagy-Related Protein 5 | GTP Phosphohydrolases - genetics | Mitochondria - virology | TNF Receptor-Associated Factor 6 - metabolism | RNA, Small Interfering | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2013, Volume 123, Issue 3, pp. 1068 - 1081
Despite advances in clinical therapy, metastasis remains the leading cause of death in breast cancer patients. Mutations in mitochondrial DNA, including those... 
CARCINOMA-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | MAMMARY-TUMORS | METABOLIC SWITCH | AUTOPHAGY | NADH-QUINONE OXIDOREDUCTASE | TRANSCRIPTIONAL REGULATION | SACCHAROMYCES-CEREVISIAE | SIRT1 | DNA MUTATIONS | Neoplasm Transplantation | Cell Proliferation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Multiprotein Complexes | NAD - physiology | Saccharomyces cerevisiae Proteins - biosynthesis | Recombinant Proteins - biosynthesis | Mammary Neoplasms, Experimental - metabolism | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Autophagy | Niacin - pharmacology | Brain Neoplasms - metabolism | Gene Knockdown Techniques | Mechanistic Target of Rapamycin Complex 1 | Brain Neoplasms - secondary | Lung Neoplasms - secondary | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | Mammary Neoplasms, Experimental - pathology | Female | Electron Transport Complex I - physiology | Acrylamides - pharmacology | NAD - metabolism | Cytokines - metabolism | Mitochondria - metabolism | Mice, SCID | Disease Progression | Protein Transport | Animals | Proteins - metabolism | Autophagy-Related Protein 5 | Electron Transport Complex I - biosynthesis | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Saccharomyces cerevisiae Proteins - physiology | TOR Serine-Threonine Kinases | Cytokines - antagonists & inhibitors | Niacinamide - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 07/2011, Volume 124, Issue 4, pp. 444 - 453
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 01/2015, Volume 308, Issue 1, pp. L33 - L47
Mutation of threonine for isoleucine at codon 73 (I73T) in the human surfactant protein C (hSP-C) gene (SFTPC) accounts for a significant portion of SFTPC... 
Surfactant protein | Pulmonary fibrosis | Alveolar epithelium | Autophagy | Amphisome | alveolar epithelium | autophagy | amphisome | surfactant protein | pulmonary fibrosis | DOMAIN | PHYSIOLOGY | SURFACTANT PROTEIN-C | AGGRESOME FORMATION | ENDOPLASMIC-RETICULUM STRESS | RAT TYPE-II | LYSOSOMAL STORAGE DISORDERS | EPITHELIAL-CELLS | MULTIVESICULAR BODIES | RESPIRATORY SYSTEM | PULMONARY-FIBROSIS | Proteostasis Deficiencies - metabolism | Lung Diseases, Interstitial - metabolism | Vacuoles - ultrastructure | Lung Diseases, Interstitial - pathology | Microtubule-Associated Proteins - genetics | Sequestosome-1 Protein | Humans | Lysosomes - genetics | Genetic Diseases, Inborn - genetics | Infant | rab GTP-Binding Proteins - genetics | Genetic Diseases, Inborn - pathology | Mutation, Missense | Mitochondria - ultrastructure | Lysosomes - metabolism | ATP-Binding Cassette Transporters - genetics | Mitochondria - genetics | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Membrane Potential, Mitochondrial - genetics | Female | Genetic Diseases, Inborn - metabolism | Microfilament Proteins - genetics | Vacuoles - genetics | Gene Expression Regulation - genetics | Proteostasis Deficiencies - pathology | Pulmonary Surfactant-Associated Protein C - metabolism | Mitochondria - metabolism | Microtubule-Associated Proteins - biosynthesis | rab GTP-Binding Proteins - biosynthesis | Ubiquitin-Protein Ligases - biosynthesis | Lysosomes - ultrastructure | Autophagy-Related Protein 8 Family | Proteostasis Deficiencies - genetics | Microfilament Proteins - biosynthesis | Lung Diseases, Interstitial - genetics | Adaptor Proteins, Signal Transducing - genetics | Pulmonary Surfactant-Associated Protein C - genetics | Vacuoles - metabolism | Adaptor Proteins, Signal Transducing - biosynthesis | Ubiquitin-Protein Ligases - genetics | Amino Acid Substitution | Autophagy (Cytology) | Usage | Genetic aspects | Epithelium | Health aspects | Lung diseases | Proteins | ABC transporters | Mutation | Biomass | Surfactants | Cells | Index Medicus | Call for Papers
Journal Article
Journal Article
International Journal of Oncology, ISSN 1019-6439, 02/2017, Volume 50, Issue 2, pp. 365 - 372
Journal Article