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The Journal of Cell Biology, ISSN 0021-9525, 9/2005, Volume 170, Issue 7, pp. 1067 - 1078
Mutations in GDAP1 lead to severe forms of the peripheral motor and sensory neuropathy, Charcot-Marie-Tooth disease (CMT), which is characterized by... 
COS cells | Mitochondria | Transfection | Neurons | Charcot Marie Tooth disease | Schwann cells | HeLa cells | Genetic mutation | Peripheral nervous system diseases | Cells | OUTER-MEMBRANE | FUSION | NEUROPATHY | SCHWANN-CELLS | FISSION | GDAP1 GENE | MAMMALIAN-CELLS | DYNAMIN-RELATED PROTEIN | ETHACRYNIC-ACID | AUTOSOMAL RECESSIVE CMT | CELL BIOLOGY | Humans | Nerve Tissue Proteins - analysis | Microtubule-Associated Proteins - pharmacology | Neurons - cytology | Schwann Cells - cytology | Charcot-Marie-Tooth Disease - genetics | Mitochondrial Membrane Transport Proteins - genetics | Mitochondrial Membrane Transport Proteins - physiology | Mitochondrial Proteins - metabolism | Membrane Transport Proteins - metabolism | Membrane Proteins - metabolism | Neurons - metabolism | Mitochondria - chemistry | Charcot-Marie-Tooth Disease - metabolism | Nerve Tissue Proteins - physiology | Cells, Cultured | Gene Expression Regulation | Rats | Schwann Cells - metabolism | Mitochondria - pathology | Intracellular Membranes - chemistry | Nerve Tissue Proteins - genetics | Mitochondrial Proteins - pharmacology | Animals | Charcot-Marie-Tooth Disease - etiology | GTP Phosphohydrolases - metabolism | Models, Biological | Mice | Mutation | Mitochondria - physiology | GTP Phosphohydrolases - pharmacology | Proteins | Care and treatment | Research | Gangliosides | Charcot-Marie-Tooth disease
Journal Article
Journal of Cell Science, ISSN 0021-9533, 02/2010, Volume 123, Issue 4, pp. 619 - 626
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 44, pp. 18880 - 18885
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 42, pp. 17396 - 17401
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Brain Research Reviews, ISSN 0165-0173, 2010, Volume 67, Issue 1, pp. 103 - 118
Journal Article
Circulation Research, ISSN 0009-7330, 05/2012, Volume 110, Issue 11, pp. 1484 - 1497
RATIONALE:Pulmonary arterial hypertension (PAH) is a lethal syndrome characterized by pulmonary vascular obstruction caused, in part, by pulmonary artery... 
mitotic checkpoint | cyclin B1/cyclin-dependent kinase 1 | mitochondrial fission | hypoxia-inducible factor-1 | mitochondrial division inhibitor-1 | CARDIAC & CARDIOVASCULAR SYSTEMS | ENTRY | INDUCIBLE FACTOR 1-ALPHA | HYPOXIA | DRP1 | PATHWAY | ARTERIAL-HYPERTENSION | ENDOTHELIAL-CELLS | GENE-EXPRESSION | GERMLINE MUTATIONS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | K+ CHANNELS | Antihypertensive Agents - pharmacology | Humans | Monocrotaline | Male | Cyclin B1 - metabolism | Cobalt | Hypertension, Pulmonary - therapy | CDC2 Protein Kinase - metabolism | RNA Interference | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mitochondrial Proteins - metabolism | Myocytes, Smooth Muscle - drug effects | Hypertension, Pulmonary - enzymology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Myocytes, Smooth Muscle - enzymology | Dynamins - genetics | Rats | Familial Primary Pulmonary Hypertension | Hypoxia - complications | Rats, Sprague-Dawley | Pulmonary Artery - enzymology | Cell Cycle Checkpoints | GTP Phosphohydrolases - metabolism | GTP Phosphohydrolases - genetics | Mitochondria, Muscle - drug effects | Enzyme Activation | Hypertension, Pulmonary - etiology | Muscle, Smooth, Vascular - enzymology | Dynamins - metabolism | Phosphorylation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Serine | Myocytes, Smooth Muscle - pathology | Mitochondrial Proteins - genetics | Case-Control Studies | Transfection | Quinazolinones - pharmacology | Mitochondria, Muscle - enzymology | Mitochondria, Muscle - pathology | Cells, Cultured | Muscle, Smooth, Vascular - pathology | Animals | Mitosis - drug effects | Glycolysis | Cell Proliferation - drug effects | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Genetic Therapy - methods | Hypoxia-inducible factor 1 | CDK1-cyclin B1 | Mitochondrial division inhibitor-1 (Mdivi-1) | Mitochondrial fission | Mitotic check point
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2018, Volume 20, Issue 9, pp. 1023 - 1023
Endocytosis mediates the cellular uptake of micronutrients and the turnover of plasma membrane proteins. Clathrin-mediated endocytosis is the major uptake... 
CDC42 | DOMAIN | BAR | LINKED MENTAL-RETARDATION | CLATHRIN-INDEPENDENT ENDOCYTOSIS | EGF-RECEPTOR | PATHWAY | LEADING-EDGE | PROTEIN GRAF1 | ACTIN CYTOSKELETON | CELL BIOLOGY | Phosphatidylinositol Phosphates - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | cdc42 GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | GTPase-Activating Proteins - metabolism | Endocytosis | Time Factors | HEK293 Cells | Minor Histocompatibility Antigens - genetics | Cell Membrane - metabolism | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Intracellular Signaling Peptides and Proteins - genetics | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - metabolism | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases - genetics | Signal Transduction | Membrane Proteins - genetics | Rats | Carrier Proteins - genetics | Minor Histocompatibility Antigens - metabolism | Animals | Carrier Proteins - metabolism | cdc42 GTP-Binding Protein - genetics | Protein Binding | GTPase-Activating Proteins - genetics | Clathrin | Cell membranes | Research | Analysis | Cdc42 protein | GTP | Deactivation | Stimulation | Activation | Membrane proteins | Proteins | Phosphatidylinositol | Micronutrients | Receptors | Inositol polyphosphate 5-phosphatase | Dismantling | Guanosinetriphosphatase
Journal Article