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Journal Article
NMR in Biomedicine, ISSN 0952-3480, 06/2011, Volume 24, Issue 5, pp. 473 - 482
Early imaging or blood biomarkers of tumor response is needed to customize anti‐tumor therapy on an individual basis. This study evaluates the sensitivity and... 
brain tumor | blood volume fraction (BVf) | therapies | apparent diffusion coefficient (ADC) of water | vessel size index (VSI) | contrast enhancement MRI | Blood volume fraction (BVf) | Brain tumor | Therapies | Vessel size index (VSI) | Contrast enhancement MRI | Apparent diffusion coefficient (ADC) of water | DCE-MRI | RECURRENT GLIOBLASTOMA | TUMOR ANGIOGENESIS | SORAFENIB | BLOOD-VOLUME | CANCER | ANTIANGIOGENIC THERAPY | VESSEL SIZE | BIOPHYSICS | SPECTROSCOPY | IN-VIVO | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HIGH-GRADE GLIOMA | Niacinamide - analogs & derivatives | Humans | Blood Volume - drug effects | Magnetic Resonance Imaging - methods | Microvessels - pathology | Male | Benzenesulfonates - therapeutic use | Phenylurea Compounds | Rats, Nude | Benzenesulfonates - pharmacology | Carmustine - therapeutic use | Glioma - pathology | Angiogenesis Inhibitors - therapeutic use | Cell Death - drug effects | Pyridines - therapeutic use | Angiogenesis Inhibitors - pharmacology | Microvessels - drug effects | Rats | Carmustine - pharmacology | Glioma - blood supply | Animals | Models, Biological | Staining and Labeling | Survival Analysis | Cell Line, Tumor | Pyridines - pharmacology | Glioma - drug therapy | Drugs | N.M.R | Glioma | Growth rate | Magnetic resonance imaging | Brain tumors | Glioma cells | biomarkers | Cytotoxicity | Diffusion coefficient | Blood | Tumors | Index Medicus | Apparent diffusion coefficient of water (ADC)
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 2796 - 2801
Retrospective clinical studies have used immune-based biomarkers, alone or in combination, to predict survival outcomes for women with breast cancer (BC);... 
T lymphocytes | Cytometry | Lymphocytes | Breasts | BREAST CANCER SPECIAL FEATURE | Residual neoplasm | Breast cancer | Leukocytes | Macrophages | Tumors | Cancer | Inflammation | Macrophage | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | VEGF EXPRESSION | macrophage | MICROVESSEL DENSITY | MAMMARY-TUMORS | inflammation | MOUSE MODEL | REGULATORY T-CELLS | TUMOR-ASSOCIATED MACROPHAGES | CARCINOMA | PROGRESSION | ENDOTHELIAL GROWTH-FACTOR | Neoplasm, Residual - pathology | Leukocytes - pathology | Breast Neoplasms - immunology | Humans | Antineoplastic Agents - therapeutic use | Cell Lineage - drug effects | Antigens, CD - metabolism | Leukocytes - immunology | Lymphocyte Activation - immunology | Myeloid Cells - immunology | T-Lymphocytes - drug effects | Biomarkers, Tumor - metabolism | Female | Myeloid Cells - drug effects | Neoadjuvant Therapy | Neoplasm, Residual - immunology | Antineoplastic Agents - pharmacology | T-Lymphocytes - pathology | Cytotoxicity, Immunologic - drug effects | Lymphocytes, Tumor-Infiltrating - drug effects | Breast Neoplasms - drug therapy | Cell Movement - drug effects | Phenotype | Lymphocytes, Tumor-Infiltrating - pathology | Breast Neoplasms - pathology | Lymphocyte Activation - drug effects | Antigens, Differentiation, Myelomonocytic - metabolism | Leukocytes - drug effects | T-Lymphocytes - immunology | Myeloid Cells - pathology | Lymphocytes, Tumor-Infiltrating - immunology | Physiological aspects | Development and progression | Health aspects | Immunohistochemistry | Leucocytes | Biomarkers | T cell receptors | Index Medicus | Biological Sciences
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2016, Volume 375, Issue 4, pp. 323 - 334
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2012, Volume 21, Issue 3, pp. 418 - 429
Pancreatic ductal adenocarcinomas (PDAs) are characterized by a robust fibroinflammatory response. We show here that this desmoplastic reaction generates... 
INTERSTITIAL FLUID PRESSURE | SOLID TUMORS | ONCOLOGY | COMPARING STANDARD PANCREATICODUODENECTOMY | HUMAN OSTEOSARCOMA XENOGRAFTS | RANDOMIZED-TRIAL | HEAD ADENOCARCINOMA | TUMOR VASCULATURE | EXTENDED LYMPHADENECTOMY | CANCER | BLOOD-PRESSURE | CELL BIOLOGY | Adenocarcinoma - pathology | Cell Adhesion Molecules - administration & dosage | Stromal Cells - pathology | Pancreatic Neoplasms - blood supply | Deoxycytidine - pharmacology | Hyaluronic Acid - physiology | Polyethylene Glycols - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Stromal Cells - drug effects | Hyaluronoglucosaminidase - administration & dosage | Drug Evaluation, Preclinical | Hyaluronoglucosaminidase - therapeutic use | Tumor Microenvironment - drug effects | Animals, Genetically Modified | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Microvessels - drug effects | Adenocarcinoma - drug therapy | Carcinoma, Pancreatic Ductal - pathology | Extracellular Fluid - drug effects | Polyethylene Glycols - administration & dosage | Adenocarcinoma - blood supply | Hyaluronoglucosaminidase - pharmacology | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hyaluronic Acid - metabolism | Mice | Carcinoma, Pancreatic Ductal - blood supply | Cell Adhesion Molecules - therapeutic use | Deoxycytidine - analogs & derivatives | Enzymes | Medical colleges | Care and treatment | Glycosaminoglycans | Oncology, Experimental | Research | Chemotherapy | Universities and colleges | Drug therapy | Hyaluronic acid | Public health | Tumors | Cancer | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2014, Volume 4, Issue 1, pp. 4871 - 4871
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 31 - 44
Polarization of tumor-associated macrophages (TAMs) to a proangiogenic/immune-suppressive (M2-like) phenotype and abnormal, hypoperfused vessels are hallmarks... 
Clodronic Acid - pharmacology | Gene Expression - genetics | Dendritic Cells - immunology | Humans | Pregnancy Proteins - genetics | Microvessels - pathology | Pregnancy Proteins - metabolism | Chemotactic Factors - metabolism | Neoplasm Metastasis - immunology | Antibodies - immunology | Neovascularization, Pathologic - immunology | Macrophages, Peritoneal - drug effects | Macrophages - pathology | Neoplasms - blood supply | Down-Regulation - genetics | Mice, Knockout | Macrophages - metabolism | Neoplasms - immunology | Cell Line, Tumor | Placenta Growth Factor | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Macrophages, Peritoneal - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - pathology | Gene Expression - drug effects | Regional Blood Flow - genetics | Dendritic Cells - pathology | Culture Media, Conditioned - pharmacology | Lung Neoplasms - pathology | Hypoxia - metabolism | Neovascularization, Pathologic - pathology | Regional Blood Flow - drug effects | Transfection | Lung Neoplasms - secondary | Neoplasms - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Lung Neoplasms - genetics | Microvessels - ultrastructure | Cytokines - metabolism | Mice, Inbred C57BL | Microvessels - drug effects | Pregnancy Proteins - immunology | Antibodies - pharmacology | Proteins - genetics | Neoplasm Metastasis - genetics | Hypoxia - genetics | Lung Neoplasms - immunology | Animals | Proteins - metabolism | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Macrophages - drug effects | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Proteins - pharmacology | Neoplasms - pathology | Endothelial Cells - drug effects | Index Medicus
Journal Article
MOLECULAR NEUROBIOLOGY, ISSN 0893-7648, 05/2016, Volume 53, Issue 4, pp. 2451 - 2467
Elevated plasma total homocysteine (Hcy) level is associated with an increased risk of Alzheimer's disease (AD). During transsulfuration pathways, Hcy is... 
Cerebrovascular pathology | COGNITIVE PERFORMANCE | NEUROSCIENCES | MATRIX METALLOPROTEINASES | INDUCED MEMORY IMPAIRMENT | RISK-FACTOR | Blood-brain barrier dysfunction | RECEPTOR TRAFFICKING | MATRIX-METALLOPROTEINASE-9 | RAT-BRAIN | Homocysteine | Alzheimer's disease | PLASMA HOMOCYSTEINE | EXPRESSION | Dementia | Memory - drug effects | Glial Fibrillary Acidic Protein - genetics | Cadherins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Blood-Brain Barrier - physiopathology | Claudin-5 - metabolism | Microvessels - pathology | Male | Synapses - pathology | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Antigens, CD - genetics | Alzheimer Disease - pathology | Antigens, CD - metabolism | Matrix Metalloproteinase 9 - metabolism | Cadherins - genetics | Synapses - drug effects | Alzheimer Disease - physiopathology | Hydrogen Sulfide - pharmacology | Cerebrovascular Circulation - drug effects | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Alzheimer Disease - drug therapy | Microvessels - drug effects | Claudin-5 - genetics | Cystathionine beta-Synthase - metabolism | Permeability | Blood-Brain Barrier - drug effects | Nerve Tissue Proteins - genetics | Blood-Brain Barrier - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Blood-Brain Barrier - pathology | Hydrogen Sulfide - therapeutic use | Intercellular Adhesion Molecule-1 - metabolism | Animals | Intercellular Adhesion Molecule-1 - genetics | Avoidance Learning - drug effects | Alzheimer Disease - genetics | Dizocilpine Maleate - pharmacology | Hydrogen sulfide | Methyl aspartate | Brain | RNA | Neurons | Intermediate filament proteins | Index Medicus | cerebrovascular pathology | dementia | blood brain barrier dysfunction
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e68451 - e68451
Journal Article