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Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7332, pp. 105 - 110
Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced pluripotent stem cells (PSCs) into... 
VIVO | NEUROGENIN-3 | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | ENDODERM | DEFINED CONDITIONS | GENERATION | SPECIFICATION | FATE | EFFICIENT DIFFERENTIATION | ENDOCRINE-CELLS | Body Patterning - drug effects | Intestines - drug effects | Wnt Proteins - pharmacology | Embryonic Stem Cells - cytology | Humans | Endoderm - embryology | Intestines - embryology | Organogenesis - drug effects | Intestines - anatomy & histology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Endoderm - cytology | Fibroblast Growth Factor 4 - pharmacology | Cell Culture Techniques | Culture Media - chemistry | Induced Pluripotent Stem Cells - cytology | Basic Helix-Loop-Helix Transcription Factors - genetics | Induced Pluripotent Stem Cells - drug effects | Cells, Cultured | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Microvilli - drug effects | Activins - pharmacology | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Endoderm - drug effects | Culture Media - pharmacology | Morphogenesis - drug effects | Wnt3 Protein | Wnt3A Protein | Intestines - cytology | Physiological aspects | Intestines | Genetic aspects | Health aspects | Endoderm | Stem cells | Proteins | Studies | posterior endoderm | intestine | FGF | transplantation | colon | drug transport | Wnt | progenitor cell
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 07/2007, Volume 582, Issue 1, pp. 379 - 392
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 34, pp. 14037 - 14042
The soil bacterium Bacillus thuringiensis (Bt) is the most successfully used biopesticide in agriculture, and its insecticidal protein genes are the primary... 
Larvae | Midgut | Bacillus thuringiensis | Genes | Proteomics | Cadherins | Toxins | Transgenic insects | Insect genetics | Microvilli | HELICOVERPA-ARMIGERA | HELIOTHIS-VIRESCENS LARVAE | GENE | PLUTELLA-XYLOSTELLA | FIELD | MULTIDISCIPLINARY SCIENCES | INSECT RESISTANCE | DELTA-ENDOTOXIN | LEPIDOPTERA | BINDING | BT CROPS | Gene Expression Regulation, Enzymologic - drug effects | Transcription, Genetic - drug effects | Bacillus thuringiensis - chemistry | Molecular Weight | Genes, Insect - genetics | Insecticide Resistance - genetics | Molecular Sequence Data | Gene Expression Profiling | RNA, Messenger - metabolism | Moths - genetics | Bacterial Proteins - toxicity | Digestive System - drug effects | Larva - drug effects | Protein Binding - drug effects | Hemolysin Proteins - toxicity | Insecticide Resistance - drug effects | Larva - genetics | Insect Proteins - metabolism | Genetic Linkage | Digestive System - metabolism | Electrophoresis, Polyacrylamide Gel | RNA, Messenger - genetics | Insect Proteins - genetics | CD13 Antigens - metabolism | Microvilli - drug effects | Animals | CD13 Antigens - genetics | Microvilli - metabolism | Brassica - parasitology | Moths - enzymology | Endotoxins - toxicity | Moths - drug effects | Evolutionary biology | Aminopeptidases | Physiological aspects | Genetic aspects | Research | Moths | Biological Sciences
Journal Article
Journal Article
Toxicon, ISSN 0041-0101, 08/2016, Volume 118, pp. 13 - 20
Cyanobacterial blooms caused by water eutrophication have become a worldwide problem. Microcystins (MCs), especially microcystin-LR (MC-LR), released during... 
Fish | Pathological damage | Immunity | Recovery | Microcystin-LR | RAINBOW-TROUT | MUCOSAL IMMUNITY | BIOCHEMICAL-CHARACTERIZATION | ANION TRANSPORTING POLYPEPTIDES | IMMUNE-RELATED GENES | CTENOPHARYNGODON-IDELLA | CARASSIUS-AURATUS | CARP CYPRINUS-CARPIO | INFLAMMATORY-BOWEL-DISEASE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TROUT ONCORHYNCHUS-MYKISS | Intestinal Mucosa - metabolism | Spleen - immunology | Bacterial Toxins - toxicity | Gills - immunology | Spleen - drug effects | RNA, Messenger - metabolism | Intestinal Mucosa - drug effects | Immunity, Mucosal - drug effects | Inflammation Mediators - agonists | Gills - drug effects | Osmolar Concentration | Gills - ultrastructure | Intestinal Mucosa - immunology | Inflammation Mediators - metabolism | Zebrafish Proteins - agonists | Drug Resistance | Microscopy, Electron, Scanning | Immunity, Innate - drug effects | Intestinal Mucosa - ultrastructure | Zebrafish Proteins - metabolism | Gills - metabolism | Microvilli - immunology | Zebrafish | Random Allocation | Microcystins - toxicity | Organ Specificity | Spleen - ultrastructure | Gene Expression Regulation - drug effects | Microvilli - drug effects | Animals | Water Pollutants, Chemical - toxicity | Microvilli - metabolism | Microvilli - ultrastructure | Spleen - metabolism | Zebrafish Proteins - genetics | Chromatin | RNA | Transforming growth factors | Gene expression | Analysis | Eutrophication | Index Medicus | Spleen | Intestines | Blooms | Exposure | Damage
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 12/2016, Volume 20, Issue 6, pp. 716 - 730
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0199412
Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon... 
HYPERPLASTIC POLYPS | STEM-CELLS | IN-VITRO | TGF-BETA | MULTIDISCIPLINARY SCIENCES | HISTOGENESIS | MICE | CRYPT FISSION | FACTOR RECEPTOR | INTESTINAL EPITHELIAL-CELLS | COLORECTAL ADENOMAS | Biomarkers - metabolism | Cell Line | Cell Survival - drug effects | Receptors, Notch - metabolism | Mice, Inbred C57BL | Spheroids, Cellular - metabolism | Colon - drug effects | Culture Media, Conditioned - pharmacology | Spheroids, Cellular - cytology | Myofibroblasts - drug effects | Stem Cells - metabolism | Wnt Proteins - metabolism | Myofibroblasts - metabolism | Microvilli - drug effects | Animals | Microvilli - metabolism | Organoids - growth & development | Signal Transduction - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Organoids - drug effects | Colon - growth & development | Feeder Cells - cytology | Stem Cells - drug effects | Spheroids, Cellular - drug effects | Analysis | Cellular control mechanisms | Stem cells | Fibroblasts | Polyposis, Familial | Genetic aspects | Research | Cell culture | Wnt protein | Mesenchyme | Transforming growth factor-b | Stem cell transplantation | Biology | Small intestine | Proteins | Ultrafiltration | Epidermal growth factor | Organoids | Intestine | Rodents | Physiology | Colon | Conditioning | Growth factors | Medical research | Bone morphogenetic protein 4 | Epidermal growth factor receptors | Trypsin | Inhibitors | Crypts | Notch protein | Mutation
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, p. e0205994
This study investigated the effect of enteral administration of obestatin on the development of small intestine, as well as oxidative stress markers and... 
CELLS | REPAIR | PROTEIN | GENE | GHRELIN | DNA | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | STRESS | EXPRESSION | Intestinal Mucosa - metabolism | Ghrelin - administration & dosage | Rats, Wistar | Body Weight - drug effects | Gene Expression Profiling | RNA, Messenger - metabolism | Intestinal Mucosa - drug effects | Intestinal Mucosa - growth & development | Peptides - metabolism | Cyclooxygenase 2 - genetics | Animals, Suckling | Intestine, Small - growth & development | Female | Microvilli - enzymology | Stomach - drug effects | DNA Repair - drug effects | Adiposity - drug effects | RNA, Messenger - genetics | Ghrelin - pharmacology | Enteral Nutrition | Gene Expression Regulation - drug effects | Microvilli - drug effects | Ghrelin - blood | Animals | Intestine, Small - drug effects | Cyclooxygenase 2 - metabolism | Intestine, Small - metabolism | Body mass index | Rats as laboratory animals | Gastrointestinal system | Body weight | Development and progression | Genetic aspects | Health aspects | Oxidative stress | Peptides | Epithelial cells | Mucosa | Biochemistry | Remodeling | Small intestine | Suckling behavior | Proteins | Toxicology | Rodents | Physiology | Life sciences | Deoxyribonucleic acid--DNA | Euthanasia | Stomach | Nutrition | Markers | Rats | MAP kinase | Saline solutions | Gene expression | Studies | Body mass | Protein kinase | Deoxyribonucleic acid
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 12/2017, Volume 390, Issue 12, pp. 1271 - 1284
Therapeutic use of cisplatin (CP), an effective anticancer drug, is limited by dose dependent nephrotoxicity. Thymoquinone (TQ), the major Nigella sativa seed... 
Neurosciences | Biomedicine | Nigella sativa | Thymoquinone | Pharmacology/Toxicology | Antioxidant | Nephrotoxicity | Cisplatin | NIGELLA-SATIVA OIL | FLAXSEED OIL | OXIDATIVE STRESS | INTESTINE | SUPPLEMENTATION | GLUTATHIONE | RENAL TOXICITY | PHARMACOLOGY & PHARMACY | INDUCED NEPHROTOXICITY | CARBOHYDRATE-METABOLISM | Carbohydrate Metabolism - drug effects | Kidney Cortex - drug effects | Rats, Wistar | Kidney - enzymology | Body Weight - drug effects | Lysosomes - enzymology | Male | Antineoplastic Agents - toxicity | Kidney - metabolism | Cisplatin - toxicity | Kidney Diseases - chemically induced | Antineoplastic Agents - pharmacology | Cisplatin - antagonists & inhibitors | Kidney Medulla - pathology | Microvilli - enzymology | Lysosomes - drug effects | Kidney - drug effects | Oxidation-Reduction | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Kidney Medulla - drug effects | Rats | Kidney Cortex - pathology | Benzoquinones - pharmacology | Microvilli - drug effects | Animals | Oxidative Stress - drug effects | Energy Metabolism - drug effects | Antioxidants | Antimitotic agents | Enzymes | Medical research | Urea | Physiological aspects | Medicine, Experimental | Islamic schools | Carbohydrate metabolism | Dosage and administration | Antineoplastic agents | Urine | Creatinine | Carbohydrates | Energy metabolism | Syngeneic grafts | Oral administration | Metabolism | Recovery | Anticancer properties | Rodents | Renal cortex | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 12, pp. 4707 - 4712
Journal Article