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1. Puerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors Expression
by Peng, Jing-Hua and Cui, Tuan and Huang, Fu and Chen, Liang and Zhao, Yu and Xu, Lin and Xu, Li-Li and Feng, Qin and Hu, Yi-Yang
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 03/2013, Volume 344, Issue 3, pp. 646 - 654
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Tight Junctions - genetics | Isoflavones - pharmacology | Male | Alanine Transaminase - blood | Alcohol-Related Disorders - genetics | Antigens, CD - genetics | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Liver Diseases, Alcoholic - drug therapy | Zonula Occludens-1 Protein - metabolism | Neutrophil Infiltration - drug effects | Disease Models, Animal | Tight Junctions - drug effects | Tight Junctions - metabolism | Zonula Occludens-1 Protein - genetics | Fatty Liver - metabolism | Portal Vein - metabolism | Liver - metabolism | Rats | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 2 - metabolism | Neutrophil Infiltration - genetics | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Fatty Liver - drug therapy | Triglycerides - metabolism | Microvilli - genetics | Aspartate Aminotransferases - blood | Diet | Microvilli - metabolism | Receptors, Immunologic - genetics | Intestines - drug effects | Tumor Necrosis Factor-alpha - metabolism | Liver - enzymology | Intestines - metabolism | Acute-Phase Proteins - genetics | Alcohol-Related Disorders - drug therapy | Lipopolysaccharide Receptors - metabolism | Alcohol-Related Disorders - metabolism | Liver Diseases, Alcoholic - genetics | Receptors, Immunologic - biosynthesis | Kupffer Cells - metabolism | Endotoxins - metabolism | Fatty Liver - genetics | Portal Vein - drug effects | Acute-Phase Proteins - metabolism | Endotoxins - genetics | gamma-Glutamyltransferase - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Liver Diseases, Alcoholic - metabolism | Kupffer Cells - drug effects | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Microvilli - drug effects | Endotoxins - antagonists & inhibitors | Animals | Carrier Proteins - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Lipopolysaccharide Receptors - genetics | Receptors, Immunologic - metabolism
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2. Full Text Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3
by Vogel, Georg F and Klee, Katharina M.C and Janecke, Andreas R and Müller, Thomas and Hess, Michael W and Huber, Lukas A
The Journal of cell biology, ISSN 0021-9525, 11/2015, Volume 211, Issue 3, pp. 587 - 604
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Glucose Transporter Type 5 - metabolism | Epithelial Cells - metabolism | Vesicular Transport Proteins - metabolism | Humans | R-SNARE Proteins - metabolism | Munc18 Proteins - metabolism | Malabsorption Syndromes - metabolism | Exocytosis - physiology | Myosin Heavy Chains - metabolism | Sodium-Hydrogen Exchangers - metabolism | Epithelial Cells - physiology | Mutation - physiology | Mucolipidoses - metabolism | HEK293 Cells | Cell Membrane - metabolism | Caco-2 Cells | Microvilli - pathology | rab GTP-Binding Proteins - metabolism | Cell Line | Myosin Type V - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Microvilli - metabolism | Qa-SNARE Proteins - metabolism | Cell Line, Tumor | Cell Polarity - physiology | Signal Transduction - physiology | Sodium-Hydrogen Exchanger 3 | Gene mutations | Cellular control mechanisms | Genetic aspects | Exocytosis | Properties | Observations | Molecular motors (Biochemistry) | Genomes | Mutation | Newborn babies | Cellular biology | Index Medicus | s
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3. Full Text Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2
by Oliver J. Mace and Julie Affleck and Nick Patel and George L. Kellett
The Journal of Physiology, ISSN 0022-3751, 07/2007, Volume 582, Issue 1, pp. 379 - 392
Neurosciences | Physiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Glucose Transporter Type 2 - agonists | Intestinal Mucosa - metabolism | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | Calcium - metabolism | Enterocytes - metabolism | Sucrose - analogs & derivatives | Intestinal Absorption - drug effects | Sucrose - pharmacology | Type C Phospholipases - metabolism | Male | Glucose Transporter Type 2 - metabolism | Intestinal Mucosa - drug effects | Jejunum - metabolism | Dose-Response Relationship, Drug | Intestinal Mucosa - cytology | Jejunum - drug effects | Phospholipase C beta | Time Factors | Isoenzymes - metabolism | Thiazines - pharmacology | Transducin - metabolism | Jejunum - cytology | Receptors, G-Protein-Coupled - drug effects | Paneth Cells - metabolism | Sweetening Agents - pharmacology | Rats | Microvilli - drug effects | Animals | Enterocytes - drug effects | Microvilli - metabolism | Signal Transduction - drug effects | Paneth Cells - drug effects | Perfusion | Glucose - metabolism | Saccharin - pharmacology | Index Medicus | Alimentary
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4. Full Text Organizing cell renewal in the intestine: stem cells, signals and combinatorial control
by Crosnier, Cécile and Lewis, Julian and Stamataki, Despina
Nature reviews. Genetics, ISSN 1471-0056, 05/2006, Volume 7, Issue 5, pp. 349 - 359
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Brain - cytology | Skin - cytology | Cell Proliferation | Signal Transduction | Receptors, Notch - metabolism | Skin - metabolism | Intestines - embryology | Intestines - metabolism | Stem Cells - cytology | Drosophila Proteins - metabolism | Stem Cells - metabolism | Wnt Proteins - metabolism | Brain - metabolism | Bone Morphogenetic Proteins - metabolism | Animals | Microvilli - metabolism | Models, Biological | Bone Marrow - metabolism | Cell Division | Cell Differentiation | Membrane Proteins - metabolism | Intestines - cytology | Index Medicus
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5. Full Text MYO5B and bile salt export pump contribute to cholestatic liver disorder in microvillous inclusion disease
by Girard, Muriel and Lacaille, Florence and Verkarre, Virginie and Mategot, Raphael and Feldmann, Gerard and Grodet, Alain and Sauvat, Frédérique and Irtan, Sabine and Davit‐Spraul, Anne and Jacquemin, Emmanuel and Ruemmele, Frank and Rainteau, Dominique and Goulet, Olivier and Colomb, Virginie and Chardot, Christophe and Henrion‐Caude, Alexandra and Debray, Dominique
Hepatology (Baltimore, Md.), ISSN 0270-9139, 07/2014, Volume 60, Issue 1, pp. 301 - 310
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Cholestasis - genetics | Cholestasis - metabolism | Enterocytes - metabolism | Humans | Child, Preschool | Myosin Heavy Chains - genetics | Hepatocytes - pathology | Infant | Male | rab GTP-Binding Proteins - genetics | Hepatocytes - metabolism | Malabsorption Syndromes - metabolism | Myosin Heavy Chains - metabolism | Endosomes - metabolism | Mucolipidoses - metabolism | Diarrhea, Infantile - metabolism | Female | Enterocytes - pathology | Microvilli - pathology | rab GTP-Binding Proteins - metabolism | Myosin Type V - metabolism | Diarrhea, Infantile - pathology | Bile Acids and Salts - metabolism | Mucolipidoses - genetics | Endosomes - pathology | Malabsorption Syndromes - genetics | Cholestasis - pathology | Homozygote | Microvilli - genetics | Mucolipidoses - pathology | Myosin Type V - genetics | Microvilli - metabolism | Biopsy | Heterozygote | Diarrhea, Infantile - genetics | Malabsorption Syndromes - pathology | Liver | Mutation | Bile | Index Medicus
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6. Full Text Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCα‐dependent manner
by Zhao, Luqing and Bartnikas, Thomas and Chu, Xiangpeng and Klein, Janet and Yun, Chris and Srinivasan, Shanthi and He, Peijian
The FASEB journal, ISSN 0892-6638, 03/2019, Volume 33, Issue 3, pp. 3549 - 3561
HIF2α ubiquitination | diabetes | iron uptake | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Protein Kinase C-alpha - metabolism | Humans | Middle Aged | Male | Mice, Transgenic - metabolism | Iron - metabolism | Hyperglycemia - metabolism | Transcription Factors - metabolism | Animals | Microvilli - metabolism | Duodenum - metabolism | Glucose - metabolism | Adult | Aged | Biological Transport - physiology | Membrane Proteins - metabolism | Mice | Ubiquitination - physiology | Diabetes Mellitus, Experimental - metabolism | Index Medicus | Research
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7. Full Text LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
by Alegre-Abarrategui, Javier and Christian, Helen and Lufino, Michele M.P and Mutihac, Ruxandra and Venda, Lara Lourenço and Ansorge, Olaf and Wade-Martins, Richard
Human molecular genetics, ISSN 0964-6906, 11/2009, Volume 18, Issue 21, pp. 4022 - 4034
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Diverse techniques | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | RNA, Small Interfering - genetics | Immunoprecipitation | Caveolae - ultrastructure | Membrane Microdomains - metabolism | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | Immunoblotting | Green Fluorescent Proteins - genetics | Autophagy | Membrane Microdomains - ultrastructure | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Microscopy, Immunoelectron | Brain - metabolism | Transfection | Endosomes - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Green Fluorescent Proteins - metabolism | Caveolae - metabolism | Protein-Serine-Threonine Kinases - genetics | Parkinson Disease - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Microvilli - metabolism | Microvilli - ultrastructure | Protein Binding | Recombinant Fusion Proteins - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus
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8. Full Text Evidence for a causal link between adaptor protein PDZK1 downregulation and Na+/H+ exchanger NHE3 dysfunction in human and murine colitis
by Yeruva, Sunil and Yeruva, Sunil and Chodisetti, Giriprakash and Chodisetti, Giriprakash and Luo, Min and Luo, Min and Chen, Mingmin and Chen, Mingmin and Cinar, Ayhan and Cinar, Ayhan and Ludolph, Lisa and Ludolph, Lisa and Lünnemann, Maria and Lünnemann, Maria and Goldstein, Julia and Goldstein, Julia and Singh, Anurag Kumar and Singh, Anurag Kumar and Riederer, Brigitte and Riederer, Brigitte and Bachmann, Oliver and Bachmann, Oliver and Bleich, Andre and Bleich, Andre and Gereke, Markus and Gereke, Markus and Bruder, Dunja and Bruder, Dunja and Hagen, Susan and Hagen, Susan and He, Peijian and He, Peijian and Yun, Chris and Yun, Chris and Seidler, Ursula and Seidler, Ursula
Pflügers Archiv, ISSN 0031-6768, 8/2015, Volume 467, Issue 8, pp. 1795 - 1807
Inflammatory bowel disease | Biomedicine | Sodium absorption | Human Physiology | Intestinal inflammation | pH regulation | Electrolyte transport | Life Sciences & Biomedicine | Physiology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Dextran Sulfate | Ileum - pathology | Enterocytes - metabolism | Colitis - genetics | Humans | Ileitis - chemically induced | Tumor Necrosis Factor-alpha - genetics | Ileum - metabolism | Colitis - pathology | Intracellular Signaling Peptides and Proteins - metabolism | Mice, 129 Strain | RNA, Messenger - metabolism | Ileitis - pathology | Sodium-Hydrogen Exchangers - metabolism | DNA-Binding Proteins - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Transfection | RNA Interference | Colitis - chemically induced | Inflammation Mediators - metabolism | Interleukin-10 - metabolism | Sodium-Hydrogen Exchangers - genetics | Enterocytes - pathology | Ileitis - metabolism | Retrospective Studies | Intracellular Signaling Peptides and Proteins - genetics | Disease Models, Animal | Caco-2 Cells | Colon - pathology | Down-Regulation | DNA-Binding Proteins - genetics | Colon - metabolism | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Microvilli - metabolism | Biopsy | Interleukin-10 - genetics | Colitis - metabolism | Ileitis - genetics | Sodium-Hydrogen Exchanger 3 | Index Medicus | Molecular and Cellular Mechanisms of Disease
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